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Recent Advances In Pancreatitis
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Book Synopsis Recent Advances in Pancreatitis by : Qiang Yan
Download or read book Recent Advances in Pancreatitis written by Qiang Yan and published by BoD – Books on Demand. This book was released on 2022-02-02 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pancreatitis is a common disease of the digestive system with a high mortality and complication rate. This book provides a comprehensive discussion of the anatomy and physiology of the pancreas, acute and chronic pancreatitis, and minimally invasive treatment in pancreatitis. The target audience comprises scholars and specialists in the field.
Book Synopsis Recent advances in Pancreatology by : Atsushi Masamune
Download or read book Recent advances in Pancreatology written by Atsushi Masamune and published by Frontiers E-books. This book was released on 2014-11-19 with total page 70 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pancreatic diseases include intractable ones including acute and chronic pancreatitis, and pancreatic cancer. In recent years, great advances have been made in the field of pancreatology, including the pathogenesis, diagnostic modalities, and development of novel therapeutic interventions. It has been established that pancreatic stellate cells play a pivotal role in the development of pancreatic fibrosis in chronic pancreatitis as well as in pancreatic cancer known as desmoplastic reaction. Although it might be still controversial, accumulating evidence has shown that interaction between pancreatic stellate cells-cancer cells contribute to the progression of pancreatic cancer through the increased proliferation and migration, and production of cytokines and extracellular matrix components. In addition, pancreatic stellate cells lead to the resistance to chemotherapy and radiation therapy. Pancreatic stellate cells attract the researchers as a novel therapeutic target of pancreatic cancer. Genetic studies have shown that mutations in the trypsin-related genes such as cationic trypsinogen (PRSS1) gene and the serine protease inhibitor, Kazal type 1 (SPINK1) gene are associated with pancreatitis. In general, each of these factors appears to limit trypsin activation or enhance inactivation, and is believed to increase intrapancreatic trypsin activity and predispose to pancreatitis when the gene is mutated. These results have supported a concept that pancreatic protease/anti-protease plays pivotal roles in the pathogenesis of pancreatitis. In addition, genetic studies focusing on phenotypic variances would provide us with important information how genetic variants would affect the phenotypic variances. Autophagy is an intracellular bulk degradation system in which cytoplasmic components are directed to the lysosome/vacuole by a membrane-mediated process. Recent studies have highlighted a role of autophagy in acute pancreatitis. Using a conditional knockout mouse that lacks the autophagy-related (Atg) gene Atg5 in the pancreatic acinar cells, autophagy exerts a detrimental effect in pancreatic acinar cells by activation of trypsinogen to trypsin. A theory in which autophagy accelerates trypsinogen activation by lysosomal hydrolases under acidic conditions, thus triggering acute pancreatitis in its early stage. The epithelial-mesenchymal transition is a developmental process that allows a polarized epithelial cell to undergo multiple biochemical changes that enable it to assume a mesenchymal phenotype. The phenotype associated with epithelial-mesenchymal transition includes enhanced migratory capacity, invasiveness, elevated resistance to apoptosis, and greatly increased production of extracellular matrix components. In addition to its role in development, tissue regeneration, and fibrosis, epithelial-mesenchymal transition is now considered as a critical process in cancer progression. Induction of epithelial-mesenchymal transition in cancer cells results in the acquisition of invasive and metastatic properties. Epithelial-mesenchymal transition could be an important mechanism in the progression of pancreatic cancer and its poor prognosis. Autoimmune pancreatitis is a unique form of pancreatitis in which autoimmune mechanisms are suspected to be involved in the pathogenesis. There is accumulating study to deal with this new disease concept. In addition to these topics, we have selected several topics in pancreatology, focusing on recent studies increasingly deepening our knowledge in both basic and clinical researches.
Book Synopsis Recent Advances in Pancreas - ECAB - E-Book by : Nageshwar Reddy
Download or read book Recent Advances in Pancreas - ECAB - E-Book written by Nageshwar Reddy and published by Elsevier Health Sciences. This book was released on 2014-12-12 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent Advances in Pancreas - ECAB - E-Book
Book Synopsis Pancreatitis and Its Complications by : Chris E. Forsmark
Download or read book Pancreatitis and Its Complications written by Chris E. Forsmark and published by Springer Science & Business Media. This book was released on 2007-10-27 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diseases of the pancreas have been extremely difficult to study. Until relatively recently, the pancreas was viewed by surgeons as an organ to be avoided, given its deep retroperitoneal location and the sometimes severe consequences of manipulation. Similar difficulties have plagued careful study of the pancreas. In humans, only inf- quently have we had the opportunity to evaluate the evolution of d- eases of the pancreas; instead, we are confronted with end-stage chronic pancreatitis or acute pancreatitis with extensive necrosis of the gland. Within the past decade, revolutionary techniques in molecular biology, genetics, and animal models have begun to give us dramatic new insights into pancreatic disease. Coupled with these advances has been a slow but steady progress in the development of our clinical tools for diagnosing and treating pancreatic diseases. These advances place us on the threshold of a much more complete understanding of pancreatic diseases, opening up new opportunities for novel therapies and preventive measures. Pancreatitis and Its Complications brings together many of the world’s experts in pancreatic diseases. These “pancreatologists” include basic scientists, endoscopists, gastroenterologists, and surgeons. The ch- ters have been organized to provide a comprehensive discussion of acute and chronic pancreatitis, with up-to-date discussions of pat- physiology, epidemiology, diagnostic strategies, treatment, and c- plications of disease. It is hoped that this text will serve as a useful reference for clinicians as well as provide a clinical background for scientists with an interest in pancreatic or related diseases.
Book Synopsis Pancreatitis Research Advances by : William C. Langley
Download or read book Pancreatitis Research Advances written by William C. Langley and published by Nova Publishers. This book was released on 2007 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pancreatitis is an inflammation of the pancreas. The pancreas secretes digestive enzymes into the small intestine through a tube called the pancreatic duct. These enzymes help digest fats, proteins, and carbohydrates in food. The pancreas also releases the hormones insulin and glucagon into the bloodstream. These hormones help the body use the glucose it takes from food for energy. Normally, digestive enzymes do not become active until they reach the small intestine, where they begin digesting food. But if these enzymes become active inside the pancreas, they start 'digesting' the pancreas itself. Acute pancreatitis occurs suddenly and lasts for a short period of time and usually resolves. Chronic pancreatitis does not resolve itself and results in a slow destruction of the pancreas. In severe cases, bleeding, tissue damage, and infection may occur. Pseudocysts, accumulations of fluid and tissue debris, may also develop. And enzymes and toxins may enter the bloodstream, injuring the heart, lungs, and kidneys, or other organs. This new book presents the latest research from around the world in this field.
Book Synopsis Pancreatic Diseases—Advances in Research and Treatment: 2012 Edition by :
Download or read book Pancreatic Diseases—Advances in Research and Treatment: 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-26 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pancreatic Diseases—Advances in Research and Treatment: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Pancreatic Diseases. The editors have built Pancreatic Diseases—Advances in Research and Treatment: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Pancreatic Diseases in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Pancreatic Diseases—Advances in Research and Treatment: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Download or read book Pancreatology written by Juan Iovanna and published by Springer Science & Business Media. This book was released on 2009-07-15 with total page 97 pages. Available in PDF, EPUB and Kindle. Book excerpt: Basic research discusses the implication of pancreatic stress protein in acute pancreatitis and pancreatic cancer and their possible role as therapeutic targets. Also, very original results show the unexpected role of lipids as mediators during acute pancreatitis. Gene screening strategies allow the detection of the genes responsbile for gemcitabine resistance of pancreatic cancer cells. They lead to the selection of several target genes, in order to suppress the resistance of cells to gemcitabine treatment. The mechanism by which tetrahydrocannabinol is anti-tumoral in pancreatic cancer cells is presented and the use of THC as a promising new therapeutic agent is discussed. Genetic data are shown concerning hundreds of families with hereditary chronic pancreatitis and their possible role in the pathogenesis of the disease. Another very original study addresses the prevention and treatment of pancreatic diseases with diat. In clinical research, convincing data about the use of endoscopic sphicterotomy in the management of acute bilary pancreatitis is presented, based on the experience of a Center highly specialized in pancreatic diseases.
Download or read book Chronic Pancreatitis written by and published by . This book was released on 2006 with total page 115 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Pancreatic Cancer and Chronic Pancreatitis by : Shailesh Vinayak Shrikhande
Download or read book Pancreatic Cancer and Chronic Pancreatitis written by Shailesh Vinayak Shrikhande and published by . This book was released on 2006 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Clinical Pancreatology for Practising Gastroenterologists and Surgeons by : Juan Enrique Dominguez-Munoz
Download or read book Clinical Pancreatology for Practising Gastroenterologists and Surgeons written by Juan Enrique Dominguez-Munoz and published by John Wiley & Sons. This book was released on 2021-03-17 with total page 752 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical Pancreatology Since the book Clinical Pancreatology for Practising Gastroenterologists and Surgeons was first published sixteen years ago, the knowledge and clinical management of pancreatic diseases have developed markedly. Thanks to the development of the translational research and the from bench to bedside concept, much progress from the lab has been applied to clinical practice. In addition, several highly relevant clinical trials published over the last years have resulted in the update and optimisation of clinical guidelines. A new and validated classification of severity and complications of acute pancreatitis is firmly rooted in clinical practice and has been the basis for the development of minimally invasive approaches to pancreatic necrosis. The etiopathogenic knowledge of chronic pancreatitis and other pancreatopaties, like that associated with diabetes mellitus, has developed significantly. Especially important has been the development of the field of cystic pancreatic tumours, which has been reflected in the publication of several guidelines and consensus reports over the last few years. Most research efforts have focused on pancreatic cancer, which have led and will further lead to a significant increase in the therapeutic armamentarium against this devastating disease. Finally, many newly published studies have changed the concept, causes, clinical relevance, diagnosis and treatment of exocrine pancreatic insufficiency. This new edition of Clinical Pancreatology for Practising Gastroenterologists and Surgeons has enjoyed the collaboration of the world’s leading experts in each of the areas of clinical pancreatology with the aim of facilitating gastroenterologists, surgeons, oncologists, internists, nutritionists, diabetologists, paediatricians, radiologists, pathologists and other specialists in their decision making when facing patients with pancreatic diseases in their daily clinical practice. All in all, this book supplies an indispensable update of the relevant aspects of clinical pancreatology.
Book Synopsis Pancreatitis: Advances in Research and Treatment: 2011 Edition by :
Download or read book Pancreatitis: Advances in Research and Treatment: 2011 Edition written by and published by ScholarlyEditions. This book was released on 2012-01-09 with total page 43 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pancreatitis: Advances in Research and Treatment: 2011 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Pancreatitis in a compact format. The editors have built Pancreatitis: Advances in Research and Treatment: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Pancreatitis in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Pancreatitis: Advances in Research and Treatment: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Book Synopsis Pancreatitis—Advances in Research and Treatment: 2012 Edition by :
Download or read book Pancreatitis—Advances in Research and Treatment: 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-26 with total page 56 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pancreatitis—Advances in Research and Treatment: 2012 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Pancreatitis in a concise format. The editors have built Pancreatitis—Advances in Research and Treatment: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Pancreatitis in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Pancreatitis—Advances in Research and Treatment: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Download or read book Pancreatitis written by David B. Adams and published by John Wiley & Sons. This book was released on 2017-02-02 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pancreatitis: medical and surgical management provides gastroenterologists and GI surgeons, both fully qualified and in training, with a focused, evidence-based approach to the most exciting developments in the diagnosis and clinical management of pancreatitis. Focusing mainly on the rapidly changing and innovative medical and surgical strategies to manage the disease, new surgical procedures such as endoscopic biliary intervention and minimally invasive necrosectomy to exciting new medical therapies like Antiprotease, Lexipafant, probiotics and enzyme treatment are all discussed. Full colour throughout, with over 250 colour illustrations and with reference to the latest clinical guidelines from the AGA, ACG and UEGW at all times, it is an essential consultation tool for all those managing patients with this increasingly common condition.
Book Synopsis IgG4-Related Sclerosing Cholangitis by : Terumi Kamisawa
Download or read book IgG4-Related Sclerosing Cholangitis written by Terumi Kamisawa and published by Springer. This book was released on 2018-07-31 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book aims to raise awareness of IgG4-related sclerosing cholangitis among practicing physicians and to equip readers with a sound understanding of the principles of diagnosis and treatment. Clinical, serological, and histopathological features are clearly described and imaging appearances on all relevant modalities are illustrated, covering the bile duct and other involved organs. Differential diagnosis from other diseases, including primary sclerosing cholangitis and cholangiocarcinoma, is precisely explained. Information is then presented on all significant current and emerging therapeutic strategies, including steroids, immunosuppressive drugs, and rituximab. Finally, attention is drawn to significant prognostic features. While IgG4-related sclerosing cholangitis is now a widely acknowledged condition, most practitioners are still liable to misdiagnose it owing to a lack of familiarity with its presenting features. This book should help to rectify the situation and will be an asset for all who may encounter the disease in clinical practice.
Book Synopsis Pancreatic Disease by : Colin D. Johnson
Download or read book Pancreatic Disease written by Colin D. Johnson and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 461 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pancreatic Disease: Towards the Year 2000 provides a clear picture of the current research activity in pancreatic disease and its related basic science. Experts currently contributing to advances in understanding and treatment have provided concise and clear reviews of their subject. Each contribution summarises the relevant literature and describes recent advances whilst highlighting those areas where current research will impinge on clinical practice in the next few years. The reader will find in this book all the latest material related to pancreatic disease, cancer, acute and chronic pancreatitis and a number of other topics including transplantation and the relationship between endocrine and exocrine disease and cystic fibrosis. The book will supplement existing texts and will be of value to practising specialists who deal with pancreatic disease as well as specialist trainees in surgery and medical gastroenterology.
Book Synopsis Pancreatitis: Advances in Pathobiology, Diagnosis and Treatment by : R.W. Ammann
Download or read book Pancreatitis: Advances in Pathobiology, Diagnosis and Treatment written by R.W. Ammann and published by Falk Symposium. This book was released on 2006-04-13 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of the Falk Symposium 143 held in Freiburg, Germany, October 14-15, 2004
Book Synopsis Pancreatic Disease by : Colin D. Johnson
Download or read book Pancreatic Disease written by Colin D. Johnson and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 365 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pancreatic Disease gives an up-to-date picture of recent advances in the field and developing areas where progress can be expected in the near future. Four main areas are covered: acute pancreatitis, chronic pancreatitis, malignant disease and basic sciences. Chapters are included on imaging, pancreatic disease in childhood and pancreatic transplantation. The distinguished contributors include internationally known names in all the specialties covered. Established specialists in pancreatic disease - whether medical, surgical or radiological - will find the book an important reference source for current thinking and practice regarding all aspects of the investigation and management of patients with inflammatory and malignant disease of the pancreas. It will also provide residents, particularly those preparing for examinations, with a clear grasp of the advancing areas of knowledge in pancreatic disease that is not available from larger texts.
