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Author : Stephen Robert Bloom
Publisher : Saunders Limited.
ISBN 13 :
Total Pages : 216 pages
Book Rating : 4.3/5 (91 download)
Download or read book Radioimmunoassay of Gut Regulatory Peptides written by Stephen Robert Bloom and published by Saunders Limited.. This book was released on 1982 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : David R. Brown
Publisher : Springer Science & Business Media
ISBN 13 : 3642778143
Total Pages : 463 pages
Book Rating : 4.6/5 (427 download)
Download or read book Gastrointestinal Regulatory Peptides written by David R. Brown and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 463 pages. Available in PDF, EPUB and Kindle. Book excerpt: The most comprehensive and conceptual one-volume treatment of this field available and the first to emphasize the cellular and molecular aspects of gut peptide biology. Authored by an array of internationally distinguished scientists, it deals with issues of peptide localization and biosynthesis in gastrointestinal cells, mechanisms of peptide release and inactivation and the nature of peptide receptors. The breadth and readability make it an invaluable reference source for scientists in all disciplines interested in any aspect of brain-gut peptides.
Author : J.M. Polak
Publisher : Birkhäuser
ISBN 13 : 3034891369
Total Pages : 419 pages
Book Rating : 4.0/5 (348 download)
Download or read book Regulatory Peptides written by J.M. Polak and published by Birkhäuser. This book was released on 2013-03-07 with total page 419 pages. Available in PDF, EPUB and Kindle. Book excerpt: J. M. Polak and S. R. Bloom For some time Experientia has published, as a unique feature, interdis ciplinary multi-author reviews, giving a comprehensive overview of sub jects regarded as 'growing edges' of science. The enthusiasm shown by the readers was contagious and thus it was felt necessary to compile a special volume dealing with the novel aspects of regulatory peptides. This book covers some of the growing areas in regulatory peptide research and, although it is based on the original volume of Experientia, it is expanded and updated. The topic of 'regulatory peptides' is relatively young and has grown at an unprecedented pace, from the embryonic conception of 'gut hor mones' or 'brain neuropeptides' some 15 years ago to the realisation that these active pep tides are found, almost without exception, in every part of l8 23 the body in all vertebrate and many invertebrate species • Why the term 'regulatory peptides'? It represents a convenient label encompassing both the active peptides present in nerves, which are re leased as (putative) neurotransmitters, and those in endocrine cells, which act locally or at a distance as circulating hormones, these being the l8 main components of the so-called diffuse neuroendocrine or APUD 17 system • Morphological studies support this physiological viewpoint.
Author : Enrique Blázquez
Publisher : S. Karger AG (Switzerland)
ISBN 13 :
Total Pages : 252 pages
Book Rating : 4.3/5 (91 download)
Download or read book Gut Regulatory Peptides written by Enrique Blázquez and published by S. Karger AG (Switzerland). This book was released on 1987 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Susanne Holmgren
Publisher : Springer Science & Business Media
ISBN 13 : 9400908350
Total Pages : 502 pages
Book Rating : 4.4/5 (9 download)
Download or read book The Comparative Physiology of Regulatory Peptides written by Susanne Holmgren and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: Strictly speaking, the term regulatory peptides may include any peptide which has a regulatory function in any organism. In recent years, how ever, the term has come to mean those originally classified as brain-gut peptides. The peptides initially defined as those belonging to the brain gut axis had a dual location in neurones of the brain and endocrine cells of the gut. We now include a number of neuropeptides found in the autonomic nervous system of the gut, the cardiovascular system and other systems. To many scientists comparative physiology means comparison of the mechanisms of certain functions in the rat, the guinea-pig, the cat and maybe some other mammal. If the philosophy is that man is the centre of the universe and other mammals can be used as 'models' of man, this may well be the most useful way to study the functions of the human being, without actually chopping somebody up. However, with a some what wider perspective on life, it is easy to see the importance of a full understanding of the function of all living organisms, in its own right as well as a link in the evolution towards individuals able to survive and reproduce in very different environments. The importance of com parative studies in all living organisms cannot be emphasized too much. It has been the ambition with this book to treat all animals as equally important.
Author : Christopher P. Price
Publisher : Springer
ISBN 13 : 1349112348
Total Pages : 665 pages
Book Rating : 4.3/5 (491 download)
Download or read book Principles and Practice of Immunoassay written by Christopher P. Price and published by Springer. This book was released on 1991-06-18 with total page 665 pages. Available in PDF, EPUB and Kindle. Book excerpt: Each chapter of this book aims to explore the basic physical and chemical principles involved in the immunoassay techniques discussed. The book also looks at the optimization and limitations of methodology and concludes with a brief overview of the application of the performance of the technology.
Author : Paul J. Marangos
Publisher : Elsevier
ISBN 13 : 0323152805
Total Pages : 384 pages
Book Rating : 4.3/5 (231 download)
Download or read book Brain Receptor Methodologies Pt A written by Paul J. Marangos and published by Elsevier. This book was released on 2012-12-02 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain Receptor Methodologies, Part A, General Methods and Concepts: Amines and Acetylcholine provides information pertinent to neurotransmitter and neuromodulator receptors in brain. This book explores the methodologies that can used to address several basic and clinical problems. Organized into two sections encompassing 18 chapters, this book starts with an overview of the receptor concept, which can be validated from indirect evidence obtained in studies of the quantitative aspects of drug antagonism. This text then examines the radioligand–receptor binding interactions. Other chapters consider immunocytochemistry, which has a primary role in determining the precise distribution of regulatory peptides to neural and endocrine elements of the diffuse neuroendocrine system. The final chapter discusses the use of the radioligand binding procedure for the study of muscarinic receptors, which has expanded the area of muscarinic receptor pharmacology. Biochemists, pharmacologists, physiologists, and researchers engaged in the fields of neurobiology and neuroscience will find this book extremely useful.
Author : Guoqiao Li
Publisher : Academic Press
ISBN 13 : 0128132116
Total Pages : 738 pages
Book Rating : 4.1/5 (281 download)
Download or read book Artemisinin-Based and Other Antimalarials written by Guoqiao Li and published by Academic Press. This book was released on 2017-11-28 with total page 738 pages. Available in PDF, EPUB and Kindle. Book excerpt: Artemisinin-Based and Other Antimalarials: Detailed Account of Studies by Chinese Scientists Who Discovered and Developed Them provides a historical and scientific background of the discovery and development of artemisinin, artemisinin derivatives, combination drugs and related chemicals. It is a historical document, a scientific treatise, and a fascinating description of innovative research on new drug development that is carried out under extremely difficult conditions. The book also includes detailed experiments, physical-chemical procedures, practical methodologies and clinical trials. It is a valuable reference for students and researchers in the fields of scientific history, medicine, pharmaceutical science, chemistry, pharmacology and toxicology. - Presents details of all stages of drug development, including in vitro experiment, animal exploratory studies, animal tests for toxicity, safety and efficacy followed by stages I, II, III and IV, safety and efficacy in human volunteers and patients with malaria - Provides many physical-chemical laboratory procedures, such as NMR, MS, HPLC and X-ray diffraction used in drug development - Includes practical methodology of clinical trials from many research centers and countries to demonstrate the importance of this discovery
Author : Morris Green
Publisher : Academic Press
ISBN 13 : 0323140467
Total Pages : 309 pages
Book Rating : 4.3/5 (231 download)
Download or read book The Role of the Gastrointestinal Tract in Nutrient Delivery written by Morris Green and published by Academic Press. This book was released on 2012-12-02 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Role of the Gastrointestinal Tract in Nutrient Delivery contains the proceedings of the third annual Bristol-Myers Symposium on Nutrition Research, held on December 1-2, 1983 in Washington, D.C. Contributors focus on the knowledge and research findings concerning the role of the gastrointestinal tract in nutrient delivery. This text is organized into 15 chapters and addresses topics such as gastrointestinal motility; hormonal regulation of growth and function; the mechanisms of digestion and absorption; and the diverse effects of intestinal contents on nutrient absorption and antigenic response. The discussion begins with an overview of the gastrointestinal tract, with emphasis on factors that affect the growth of gastrointestinal mucosa and the implications for nutrition. This book then turns to kinetic and biochemical parameters related to the development of several diseases of the gastrointestinal tract. The reader is also introduced to the basic aspects of organization of the systems in which peptides act as regulators of digestion; the role of endogenous prostaglandins in the gastrointestinal tract; and gastric secretion. A chapter on the age-related functions of digestive tract organs concludes the book. This book will be of value to physicians and scientists as well as students and researchers who have an interest in the crucial role of the gastrointestinal tract in converting food into the nutrients the body uses to sustain its functions.
Author : National Library of Medicine (U.S.)
Publisher :
ISBN 13 :
Total Pages : 1956 pages
Book Rating : 4.F/5 ( download)
Download or read book Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on with total page 1956 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : G Rosselin
Publisher : World Scientific
ISBN 13 : 9814550787
Total Pages : 670 pages
Book Rating : 4.8/5 (145 download)
Download or read book Vasoactive Intestinal Peptides Pituitary Adenylate Cyclase Activating Polypeptide And Related Regulatory Peptides: From Molecular Biology To Clinical Applications written by G Rosselin and published by World Scientific. This book was released on 1994-06-21 with total page 670 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the most up-to-date information on the ever-growing class of peptides with high biological activity, which function as hormones or neurotransmitters and have analogous structures. These peptides include the Vasoactive Intestinal Peptide (VIP), the Pituitary Adenylate Cyclase-Activating Polypeptides (PACAP 38 and PACAP 27), the Peptide Histidyl-Isoleucylamide and the Histidyl-Methionine Peptide (PHI and PHM), Helodermin, Helospectin, the Growth Hormone Releasing Factor (GRF), Glucagon, the Glucagon-like Peptides I and II, Oxyntomodulin, Glicentin and Secretin.Selection, organization and special subject matter: The contributors to this volume who are leading experts in their fields, present a valuable synopsis of the significant research in the transduction of the peptide signals, and how it helps to maintain the essential environment for cellular functions and adaptation. Contributions are organized around the molecular systems involved in the normal and altered functions of the central nervous system, the endocrine systems and cellular proliferation. In addition, the book identifies potential sites to be targeted for drug design and therapeutic development in the domain of biosynthesis, inflammation and cardiovascular and digestive diseases.This book draws together information from widely-scattered literature and thus obviates the need for time-consuming research on the part of the readers. It is aimed at an international audience of pharmacologists, physiologists, clinical investigators, biochemists and researchers.
Author : John Lynn
Publisher : Butterworth-Heinemann
ISBN 13 : 1483193829
Total Pages : 596 pages
Book Rating : 4.4/5 (831 download)
Download or read book Surgical Endocrinology written by John Lynn and published by Butterworth-Heinemann. This book was released on 2013-10-22 with total page 596 pages. Available in PDF, EPUB and Kindle. Book excerpt: Surgical Endocrinology presents the fundamentals and practical application of the subject matter. It discusses the molecular background and physiology of the endocrine systems. It addresses the legal aspects of endocrine surgery such as duty of care, and breach of such duty. Some of the topics covered in the book are the principles of endocrine surgery; molecular structures of organisms; physiology of endocrine system; multiple endocrine neoplasia and molecular genetics; non-surgical management of pituitary tumors; assay formulations and automation technology; syndrome of ectopic hormone production; and anesthesia for pituitary surgery. The classifications of endocrine problems for pregnant women are fully covered. The definition and symptoms of thyrotoxicosis are discussed in detail. The text describes in depth the different histological imaging methods. The anatomy and surgery of anterior pituitary are completely presented. A chapter is devoted to the classification of pituitary adenomas and other tumours. The book can provide useful information to surgeons, doctors, students, and researchers.
Author : Seiji Nishino
Publisher : Springer Science & Business Media
ISBN 13 : 1592599508
Total Pages : 390 pages
Book Rating : 4.5/5 (925 download)
Download or read book The Orexin/Hypocretin System written by Seiji Nishino and published by Springer Science & Business Media. This book was released on 2007-11-22 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: Impairment of orexin/hypocretin signaling causes narcolepsy-cataplexy in animals and humans. Most human narcolepsy-cataplexy cases are associated with orexin/hypocretin ligand deficiency, which can be detected clinically using cerebrospinal orexin/hypocretin measures and may lead to future treatments with orexin/hypocretin replacement therapy. In The Orexin/Hypocretin System: Physiology and Pathophysiology, leading researchers and clinicians review these exciting developments to set the stage for further research on the loss of orexin/hypocretin neurons in humans, regulation of sleep and wakefulness by the orexin/hypocretin system, and the role of the orexin/hypocretin system in many other physiological processes, including feeding, autonomic regulation, and neuroendocrine regulation. Topics of interest include an assessment of the functions and the physiology of orexin/hypocretin, its pathophysiology in human narcolepsy-cataplexy, and possible pharmacological treatments. The authors also introduce several experimental methods for orexin/hypocretin research, and, using multidisciplinary approaches, explain their uses and limitations. Authoritative and state-of-the-art, The Orexin/Hypocretin System: Physiology and Pathophysiology will aid scientists in the search for novel bioactive peptides and their receptors, as well as novel physiological insights and opportunities for the clinical treatment of not only narcolepsy, but also a broad range of diseases associated with endocrine, feeding, and body weight regulation.
Author : Viktor Mutt
Publisher : Academic Press
ISBN 13 : 1483215539
Total Pages : 556 pages
Book Rating : 4.4/5 (832 download)
Download or read book Gastrointestinal Hormones written by Viktor Mutt and published by Academic Press. This book was released on 2013-10-22 with total page 556 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Metabolic Disorders, Volume 11: Gastrointestinal Hormones covers the developments in the study of gastrointestinal (GI) hormones. The book discusses the cytochemical techniques in work with GI hormones; the general aspects and problems for the radioimmunoassays of GI hormones in the 80s; and the response of the GI hormone system to the pathological changes. The text also describes the evolutional aspects of GI hormones; the cell membrane receptors for secretagogues on pancreatic acinar cells; and the synthesis of GI hormones using organic chemical or recombinant DNA techniques. Gastrin is reviewed with regard to its forms and fragments in tissues, circulating components during post- and perisecretory processing, cellular origins and distribution, actions and structure-function relations, metabolic disposal, nervous and chemical control for its release, and its role in human pathology. The book further tackles the chemical, anatomical, and biological studies on gastrin-releasing peptides, as well as the physiological actions of gastric inhibitory polypeptide. Discussions about the vasoactive intestinal peptide, incretin, enteroglucagon, neuropeptide Y, peptide HI, galanin, cholecystokinin-58, neuropeptide K, peptide YY, motilin, somatostatin-28, neurotensin, substance P, and opioid peptides are also encompassed. The text concludes by looking into the investigations on the structure and function of the head activator in hydra and in mammals. Molecular biologists, endocrinologists, histochemists, physiologists, and those involved in the research about GI hormones will find the book invaluable.
Author : John H. Walsh
Publisher : Raven Press (ID)
ISBN 13 :
Total Pages : 904 pages
Book Rating : 4.3/5 (91 download)
Download or read book Gut Peptides written by John H. Walsh and published by Raven Press (ID). This book was released on 1994 with total page 904 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides a comprehensive approach to gastrointestinal hormones, for clinicians and scientists who are interested in hormonal regulation of the gastrointestinal tract. The first section discusses general issues related to peptides as messengers, including receptors and signal transduction and control of gene expression. The second section presents the biochemical and physiological features of the gastrointestinal hormones and neuropeptides. The third section integrates these peptides into physiological and pathophysiological regulatory pathways of the gut. Annotation copyright by Book News, Inc., Portland, OR
Author : Klaus Havemann
Publisher : Springer Science & Business Media
ISBN 13 : 3642825338
Total Pages : 307 pages
Book Rating : 4.6/5 (428 download)
Download or read book Peptide Hormones in Lung Cancer written by Klaus Havemann and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: The incidence of lung cancer has reached epidemic proportions throughout the civilized world. One indication of the dimensions of this problem is that in the United States lung cancer has become the leading cause of cancer death in women as well as men. In 1912 there was a "nearly complete consensus of opinion that primary malignant neoplasms of the lung (were one) of the rarest forms of disease," according to Adler. By 1937, however, it had become clear that the incidence of lung cancer was increasing significantly; this increase has been progressive ever since. It is now well known that some lung cancers give rise to a variety of hormones which, at times, produce clinical manifestations. The association of hormone production with a "nonendocrine" tumor raises many questions, the answers to which may shed some light on the etiology of this prevalent form of cancer. This fascinating prob lem has stimulated a wide variety of studies in both the clinical and the basic sciences. A number of the more recent studies in this field were discussed at the International Symposium on Peptide Hor mones and Lung Cancer held in Marburg, West Germany, on June 18-20, 1984. This volume contains the papers that were pre sented on this occasion.
Author :
Publisher : Academic Press
ISBN 13 : 0128127368
Total Pages : 2370 pages
Book Rating : 4.1/5 (281 download)
Download or read book Encyclopedia of Pharmacy Practice and Clinical Pharmacy written by and published by Academic Press. This book was released on 2019-06-28 with total page 2370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Encyclopedia of Pharmacy Practice and Clinical Pharmacy, Three Volume Set covers definitions, concepts, methods, theories and applications of clinical pharmacy and pharmacy practice. It highlights why and how this field has a significant impact on healthcare. The work brings baseline knowledge, along with the latest, most cutting-edge research. In addition, new treatments, algorithms, standard treatment guidelines, and pharmacotherapies regarding diseases and disorders are also covered. The book's main focus lies on the pharmacy practice side, covering pharmacy practice research, pharmacovigilance, pharmacoeconomics, social and administrative pharmacy, public health pharmacy, pharmaceutical systems research, the future of pharmacy, and new interventional models of pharmaceutical care. By providing concise expositions on a broad range of topics, this book is an excellent resource for those seeking information beyond their specific areas of expertise. This outstanding reference is essential for anyone involved in the study of pharmacy practice. Provides a ‘one-stop’ resource for access to information written by world-leading scholars in the field Meticulously organized, with articles split into three clear sections, it is the ideal resource for students, researchers and professionals to find relevant information Contains concise and accessible chapters that are ideal as an authoritative introduction for non-specialists and readers from the undergraduate level upwards Includes multimedia options, such as hyperlinked references and further readings, cross-references and videos
