Radical Sam Enzymes Involved In Tetrapyrrole Biosynthesis And Insertion

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Radical SAM Enzymes Involved in Tetrapyrrole Biosynthesis and Insertion

Author : Gunhild Layer
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (138 download)

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Book Synopsis Radical SAM Enzymes Involved in Tetrapyrrole Biosynthesis and Insertion by : Gunhild Layer

Download or read book Radical SAM Enzymes Involved in Tetrapyrrole Biosynthesis and Insertion written by Gunhild Layer and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Abstract: The anaerobic biosyntheses of heme, heme d1, and bacteriochlorophyll all require the action of radical SAM enzymes. During heme biosynthesis in some bacteria, coproporphyrinogen III dehydrogenase (CgdH) catalyzes the decarboxylation of two propionate side chains of coproporphyrinogen III to the corresponding vinyl groups of protoporphyrinogen IX. Its solved crystal structure was the first published structure for a radical SAM enzyme. In bacteria, heme is inserted into enzymes by the cytoplasmic heme chaperone HemW, a radical SAM enzyme structurally highly related to CgdH. In an alternative heme biosynthesis route found in archaea and sulfate-reducing bacteria, the two radical SAM enzymes AhbC and AhbD catalyze the removal of two acetate groups (AhbC) or the decarboxylation of two propionate side chains (AhbD). NirJ, a close homologue of AhbC, is required for propionate side chain removal during the formation of heme d1 in some denitrifying bacteria. Biosynthesis of the fifth ring (ring E) of all chlorophylls is based on an unusual six-electron oxidative cyclization step. The sophisticated conversion of Mg-protoporphyrin IX monomethylester to protochlorophyllide is facilitated by an oxygen-independent cyclase termed BchE, which is a cobalamin-dependent radical SAM enzyme. Most of the radical SAM enzymes involved in tetrapyrrole biosynthesis were recognized as such by Sofia et al. in 2001 ( Nucleic Acids Res. 2001, 29, 1097−1106) and were biochemically characterized thereafter. Although much has been achieved, the challenging tetrapyrrole substrates represent a limiting factor for enzyme/substrate cocrystallization and the ultimate elucidation of the corresponding enzyme mechanisms

Structure and Function of Enzymes Involved in Tetrapyrrole Biosynthesis

Author : Ilka Ursula Heinemann
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (244 download)

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Book Synopsis Structure and Function of Enzymes Involved in Tetrapyrrole Biosynthesis by : Ilka Ursula Heinemann

Download or read book Structure and Function of Enzymes Involved in Tetrapyrrole Biosynthesis written by Ilka Ursula Heinemann and published by . This book was released on 2007 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Biosynthesis of Tetrapyrroles

Author : P. M. Jordan
Publisher :
ISBN 13 : 9780444803030
Total Pages : 0 pages
Book Rating : 4.8/5 (3 download)

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Book Synopsis Biosynthesis of Tetrapyrroles by : P. M. Jordan

Download or read book Biosynthesis of Tetrapyrroles written by P. M. Jordan and published by . This book was released on 1991 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Biological Inorganic Chemistry

Author : Robert R. Crichton
Publisher : Elsevier
ISBN 13 : 0080556221
Total Pages : 383 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Biological Inorganic Chemistry by : Robert R. Crichton

Download or read book Biological Inorganic Chemistry written by Robert R. Crichton and published by Elsevier. This book was released on 2007-12-11 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: The importance of metals in biology, the environment and medicine has become increasingly evident over the last twenty five years. The study of the multiple roles of metal ions in biological systems, the rapidly expanding interface between inorganic chemistry and biology constitutes the subject called Biological Inorganic Chemistry. The present text, written by a biochemist, with a long career experience in the field (particularly iron and copper) presents an introduction to this exciting and dynamic field. The book begins with introductory chapters, which together constitute an overview of the concepts, both chemical and biological, which are required to equip the reader for the detailed analysis which follows. Pathways of metal assimilation, storage and transport, as well as metal homeostasis are dealt with next. Thereafter, individual chapters discuss the roles of sodium and potassium, magnesium, calcium, zinc, iron, copper, nickel and cobalt, manganese, and finally molybdenum, vanadium, tungsten and chromium. The final three chapters provide a tantalising view of the roles of metals in brain function, biomineralization and a brief illustration of their importance in both medicine and the environment.Relaxed and agreeable writing style. The reader will not only fiind the book easy to read, the fascinating anecdotes and footnotes will give him pegs to hang important ideas on.Written by a biochemist. Will enable the reader to more readily grasp the biological and clinical relevance of the subject.Many colour illustrations. Enables easier visualization of molecular mechanismsWritten by a single author. Ensures homgeneity of style and effective cross referencing between chapters

Encyclopedia of Biological Chemistry

Author :
Publisher : Academic Press
ISBN 13 : 0123786312
Total Pages : 3223 pages
Book Rating : 4.1/5 (237 download)

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Book Synopsis Encyclopedia of Biological Chemistry by :

Download or read book Encyclopedia of Biological Chemistry written by and published by Academic Press. This book was released on 2013-01-08 with total page 3223 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 4-volume Encyclopedia of Biological Chemistry, Second Edition, represents the current state of a dynamic and crucial field of study. The Encyclopedia pulls together over 500 articles that help define and explore contemporary biochemistry, with content experts carefully chosen by the Editorial Board to assure both breadth and depth in its coverage. Editors-In-Chief William J. Lennarz and M. Daniel Lane have crafted a work that proceeds from the acknowledgement that understanding every living process-from physiology, to immunology, and genetics-is impossible without a grasp on the basic chemistry that provides its underpinning. Each article in the work provides an up-to-date snapshot of a given topic, written by experts, as well as suggestions for further readings for students and researcher wishing to go into greater depth. Available on-line via SciVerse ScienceDirect, the functionality of the Encyclopedia will provide easy linking to referenced articles, electronic searching, as well an online index and glossary to aid comprehension and searchability. This 4-volume set, thoroughly up-to-date and comprehensive, expertly captures this fast-moving field Curated by two esteemed editors-in-chief and an illustrious team of editors and contributors, representing the state of the field Suggestions for further readings offer researchers and students avenues for deeper exploration; a wide-ranging glossary aids comprehension

Advances in Bacterial Respiratory Physiology

Author : Robert K. Poole
Publisher : Academic Press
ISBN 13 : 0123944236
Total Pages : 350 pages
Book Rating : 4.1/5 (239 download)

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Book Synopsis Advances in Bacterial Respiratory Physiology by : Robert K. Poole

Download or read book Advances in Bacterial Respiratory Physiology written by Robert K. Poole and published by Academic Press. This book was released on 2012-12-05 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Microbial Physiology is one of the most successful and prestigious series from Academic Press, an imprint of Elsevier. It publishes topical and important reviews, interpreting physiology to include all material that contributes to our understanding of how microorganisms and their component parts work. First published in 1967, it is now in its 61st volume. The Editors have always striven to interpret microbial physiology in the broadest context and have never restricted the contents to "traditional” views of whole cell physiology. Now edited by Professor Robert Poole, University of Sheffield, Advances in Microbial Physiology continues to be an influential and very well reviewed series. Contributions from leading authorities Informs and updates on all the latest developments in the field

Prokaryotic Metabolism and Physiology

Author : Byung Hong Kim
Publisher : Cambridge University Press
ISBN 13 : 1107171733
Total Pages : 509 pages
Book Rating : 4.1/5 (71 download)

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Book Synopsis Prokaryotic Metabolism and Physiology by : Byung Hong Kim

Download or read book Prokaryotic Metabolism and Physiology written by Byung Hong Kim and published by Cambridge University Press. This book was released on 2019-05-16 with total page 509 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extensive and up-to-date review of key metabolic processes in bacteria and archaea and how metabolism is regulated under various conditions.

The Porphyrin Handbook

Author : Karl Kadish
Publisher : Elsevier
ISBN 13 : 0080923860
Total Pages : 272 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis The Porphyrin Handbook by : Karl Kadish

Download or read book The Porphyrin Handbook written by Karl Kadish and published by Elsevier. This book was released on 2012-12-02 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Porphyrin Handbook, Volume 12: The Iron and Cobalt Pigments: Biosynthesis, Structure, and Degradation provides information pertinent to every aspect of the chemistry, synthesis, spectroscopy, and structure of phthalocyanines. This book presents the biochemical and clinical aspects of genetically transmitted or drug-induced diseases associated with errors in heme metabolism. Organized into eight chapters, this volume begins with an overview of the comparison of regulatory principles in animal and plant tetrapyrrole biosynthesis. This text then examines the biology and medical implications of porphyrin systems. Other chapters consider the transformation of hemes into bile pigments, the organic synthesis of bilins, and the pathways of degradation of chlorophyll in senescent plants. This book discusses as well the biosynthesis of porphyrins, vitamin B12, and chlorophylls. The final chapter deals with genome sequencing projects that provide sources of genes encoding the enzymes needed for the synthesis of the intermediates. This book is a valuable resource for research scientists, engineers, and clinicians.

The Purple Phototrophic Bacteria

Author : C.N. Hunter
Publisher : Springer Science & Business Media
ISBN 13 : 1402088159
Total Pages : 1013 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis The Purple Phototrophic Bacteria by : C.N. Hunter

Download or read book The Purple Phototrophic Bacteria written by C.N. Hunter and published by Springer Science & Business Media. This book was released on 2008-10-11 with total page 1013 pages. Available in PDF, EPUB and Kindle. Book excerpt: Here is a comprehensive survey of all aspects of these fascinating bacteria, metabolically the most versatile organisms on Earth. It compiles 48 chapters written by leading experts, who highlight the huge progress made in studies of these bacteria since 1995.

Photosynthesis

Author : Julian J. Eaton-Rye
Publisher : Springer Science & Business Media
ISBN 13 : 940071579X
Total Pages : 874 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Photosynthesis by : Julian J. Eaton-Rye

Download or read book Photosynthesis written by Julian J. Eaton-Rye and published by Springer Science & Business Media. This book was released on 2011-11-04 with total page 874 pages. Available in PDF, EPUB and Kindle. Book excerpt: “Photosynthesis: Plastid Biology, Energy Conversion and Carbon Assimilation” was conceived as a comprehensive treatment touching on most of the processes important for photosynthesis. Most of the chapters provide a broad coverage that, it is hoped, will be accessible to advanced undergraduates, graduate students, and researchers looking to broaden their knowledge of photosynthesis. For biologists, biochemists, and biophysicists, this volume will provide quick background understanding for the breadth of issues in photosynthesis that are important in research and instructional settings. This volume will be of interest to advanced undergraduates in plant biology, and plant biochemistry and to graduate students and instructors wanting a single reference volume on the latest understanding of the critical components of photosynthesis.

Pseudomonas

Author : Juan-Luis Ramos
Publisher : Springer Science & Business Media
ISBN 13 : 1441990887
Total Pages : 750 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Pseudomonas by : Juan-Luis Ramos

Download or read book Pseudomonas written by Juan-Luis Ramos and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 750 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pseudomonas comprises three volumes covering the biology of pseudomonads in a wide context, including the niches they inhabit, the taxonomic relations among members of this group, the molecular biology of gene expression in different niches and under different environmental conditions, the analysis of virulence traits in plants, animals and human pathogens as well as the determinants that make some strains useful for biotechnological applications and promotion of plant growth. There has been growing interest in pseudomonads and a particular urge to understand the biology underlying the complex metabolism of these ubiquitous microbes. These bacteria are capable of colonizing a wide range of niches, including the soil, the plant rhizosphere and phylosphere, and animal tissues; more recently they have attracted attention because of their capacity to form biofilms, a characteristic with potentially important medical and environmental implications. The three volumes cover the following topics: - Taxonomy, - Genomics, - Life styles, - Cell Architecture, - Virulence, - Regulation, - Macromolecules, - Alternative Respiratory Substrates, - Catabolism and Biotransformations. Pseudomonas will be of use to all researchers working on these bacteria, particularly those studying microbiology, plant crops, pathogenesis, and chemical engineering. Advanced students in biology, medicine and agronomy will also find these three volumes a valuable reference during their studies.

ABC Proteins

Author : I Barry Holland
Publisher : Elsevier
ISBN 13 : 0080481876
Total Pages : 672 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis ABC Proteins by : I Barry Holland

Download or read book ABC Proteins written by I Barry Holland and published by Elsevier. This book was released on 2003-01-07 with total page 672 pages. Available in PDF, EPUB and Kindle. Book excerpt: ABC Proteins is an in-depth, up-to-date analysis of all that is known about the subject to date. It discusses and compares evolution, biology and mechanism of action of all known ABC proteins, including the first structural studies as well as clinical implications. It will be useful to anyone trying to stay abreast of the latest findings. This book is sure to become a classic and will regularly be updated. - Phylogeny and Evoloution of ABC Transporters - Fundamental Aspects of the Mechanism of Action of ABC Transporters - Prokaryote ABC Transporters - Non-Mammalian Transporters - Multidrug Transporters - ABC Transporters, Physiological Roles and Human Disease - Full color throughout

The Porphyrin Handbook: The iron and cobalt pigments : biosynthesis, structure, and degradation

Author :
Publisher :
ISBN 13 :
Total Pages : 280 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis The Porphyrin Handbook: The iron and cobalt pigments : biosynthesis, structure, and degradation by :

Download or read book The Porphyrin Handbook: The iron and cobalt pigments : biosynthesis, structure, and degradation written by and published by . This book was released on 2000 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Essential Microbiology

Author : Stuart Hogg
Publisher : John Wiley & Sons
ISBN 13 : 1119978912
Total Pages : 534 pages
Book Rating : 4.1/5 (199 download)

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Book Synopsis Essential Microbiology by : Stuart Hogg

Download or read book Essential Microbiology written by Stuart Hogg and published by John Wiley & Sons. This book was released on 2013-06-10 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: Essential Microbiology 2nd Edition is a fully revised comprehensive introductory text aimed at students taking a first course in the subject. It provides an ideal entry into the world of microorganisms, considering all aspects of their biology (structure, metabolism, genetics), and illustrates the remarkable diversity of microbial life by devoting a chapter to each of the main taxonomic groupings. The second part of the book introduces the reader to aspects of applied microbiology, exploring the involvement of microorganisms in areas as diverse as food and drink production, genetic engineering, global recycling systems and infectious disease. Essential Microbiology explains the key points of each topic but avoids overburdening the student with unnecessary detail. Now in full colour it makes extensive use of clear line diagrams to clarify sometimes difficult concepts or mechanisms. A companion web site includes further material including MCQs, enabling the student to assess their understanding of the main concepts that have been covered. This edition has been fully revised and updated to reflect the developments that have occurred in recent years and includes a completely new section devoted to medical microbiology. Students of any life science degree course will find this a concise and valuable introduction to microbiology.

Contemporary Aspects of Boron: Chemistry and Biological Applications

Author : Hijazi Abu Ali
Publisher : Elsevier
ISBN 13 : 0080457738
Total Pages : 631 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Contemporary Aspects of Boron: Chemistry and Biological Applications by : Hijazi Abu Ali

Download or read book Contemporary Aspects of Boron: Chemistry and Biological Applications written by Hijazi Abu Ali and published by Elsevier. This book was released on 2005-09-07 with total page 631 pages. Available in PDF, EPUB and Kindle. Book excerpt: Contemporary Aspects of Boron: Chemistry and Biological Applications highlights the biological activity and applications of boron containing compounds. The authors' specific approach surveys general features of the subject, while exploring new and novel strategies for preparing certain chemical and natural boron products that are of significant substance in medicinal chemistry. For example, cancer treatment is one of the most important issues related to such products. In addition to contributing to the development of new drugs by addressing biological applications in medicinal and industrial fields, the book provides a comprehensive review of the most relevant components that comprise the pharmaceutical, medicinal and environmental applications of boron containing compounds.* Timely and comprehensive * Provides new insights to active researchers in the field * Presents concepts and methods in simple scientific terms

The Smallest Biomolecules: Diatomics and their Interactions with Heme Proteins

Author : Abhik Ghosh
Publisher : Elsevier
ISBN 13 : 0080556329
Total Pages : 627 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis The Smallest Biomolecules: Diatomics and their Interactions with Heme Proteins by : Abhik Ghosh

Download or read book The Smallest Biomolecules: Diatomics and their Interactions with Heme Proteins written by Abhik Ghosh and published by Elsevier. This book was released on 2011-10-13 with total page 627 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is not a book on NO biology, nor about hemoglobin, nor about heme-based sensors per se. Of course, it covers all these topics and more, but above all, it aims at providing a truly multidisciplinary perspective of heme-diatomic interactions. The overarching goal is to build bridges among disciplines, to bring about a meeting of minds. The contributors to this book hail from diverse university departments and disciplines – chemistry, biochemistry, molecular biology, microbiology, zoology, physics, medicine and surgery, bringing with them very different views of heme-diatomic interactions. The hope is that the juxtaposition of this diversity will lead to increased exchanges of ideas, approaches, and techniques across traditional disciplinary boundaries. The authors represent a veritable Who's Who of heme protein research and include John Olson, Tom Spiro, Walter Zumft, F. Ann Walker, Teizo Kitagawa, W. Robert Scheidt, Pat Farmer, Marie-Alda Gilles-Gonzalez, and many other equally distinguished scientists. - Extremely distinguished list of authors - Multidisciplinary character – equally suitable for chemists and biochemists - Covers the hottest topics in heme protein research: sensors, NO biology, new roles of hemoglobin, etc.

Biomolecular EPR Spectroscopy

Author : Wilfred Raymond Hagen
Publisher : CRC Press
ISBN 13 : 1420059580
Total Pages : 264 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Biomolecular EPR Spectroscopy by : Wilfred Raymond Hagen

Download or read book Biomolecular EPR Spectroscopy written by Wilfred Raymond Hagen and published by CRC Press. This book was released on 2008-12-22 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive, Up-to-Date Coverage of Spectroscopy Theory and its Applications to Biological SystemsAlthough a multitude of books have been published about spectroscopy, most of them only occasionally refer to biological systems and the specific problems of biomolecular EPR (bioEPR). Biomolecular EPR Spectroscopy provides a practical introduction t