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R Programming For Bioinformatics
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Book Synopsis R Programming for Bioinformatics by : Robert Gentleman
Download or read book R Programming for Bioinformatics written by Robert Gentleman and published by CRC Press. This book was released on 2008-07-14 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Due to its data handling and modeling capabilities as well as its flexibility, R is becoming the most widely used software in bioinformatics. R Programming for Bioinformatics explores the programming skills needed to use this software tool for the solution of bioinformatics and computational biology problems.Drawing on the author's first-hand exper
Book Synopsis Introduction to Bioinformatics with R by : Edward Curry
Download or read book Introduction to Bioinformatics with R written by Edward Curry and published by CRC Press. This book was released on 2020-11-02 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: In biological research, the amount of data available to researchers has increased so much over recent years, it is becoming increasingly difficult to understand the current state of the art without some experience and understanding of data analytics and bioinformatics. An Introduction to Bioinformatics with R: A Practical Guide for Biologists leads the reader through the basics of computational analysis of data encountered in modern biological research. With no previous experience with statistics or programming required, readers will develop the ability to plan suitable analyses of biological datasets, and to use the R programming environment to perform these analyses. This is achieved through a series of case studies using R to answer research questions using molecular biology datasets. Broadly applicable statistical methods are explained, including linear and rank-based correlation, distance metrics and hierarchical clustering, hypothesis testing using linear regression, proportional hazards regression for survival data, and principal component analysis. These methods are then applied as appropriate throughout the case studies, illustrating how they can be used to answer research questions. Key Features: · Provides a practical course in computational data analysis suitable for students or researchers with no previous exposure to computer programming. · Describes in detail the theoretical basis for statistical analysis techniques used throughout the textbook, from basic principles · Presents walk-throughs of data analysis tasks using R and example datasets. All R commands are presented and explained in order to enable the reader to carry out these tasks themselves. · Uses outputs from a large range of molecular biology platforms including DNA methylation and genotyping microarrays; RNA-seq, genome sequencing, ChIP-seq and bisulphite sequencing; and high-throughput phenotypic screens. · Gives worked-out examples geared towards problems encountered in cancer research, which can also be applied across many areas of molecular biology and medical research. This book has been developed over years of training biological scientists and clinicians to analyse the large datasets available in their cancer research projects. It is appropriate for use as a textbook or as a practical book for biological scientists looking to gain bioinformatics skills.
Book Synopsis Bioinformatics and Computational Biology Solutions Using R and Bioconductor by : Robert Gentleman
Download or read book Bioinformatics and Computational Biology Solutions Using R and Bioconductor written by Robert Gentleman and published by Springer Science & Business Media. This book was released on 2005-12-29 with total page 478 pages. Available in PDF, EPUB and Kindle. Book excerpt: Full four-color book. Some of the editors created the Bioconductor project and Robert Gentleman is one of the two originators of R. All methods are illustrated with publicly available data, and a major section of the book is devoted to fully worked case studies. Code underlying all of the computations that are shown is made available on a companion website, and readers can reproduce every number, figure, and table on their own computers.
Book Synopsis R Bioinformatics Cookbook by : Dan MacLean
Download or read book R Bioinformatics Cookbook written by Dan MacLean and published by Packt Publishing Ltd. This book was released on 2019-10-11 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over 60 recipes to model and handle real-life biological data using modern libraries from the R ecosystem Key FeaturesApply modern R packages to handle biological data using real-world examplesRepresent biological data with advanced visualizations suitable for research and publicationsHandle real-world problems in bioinformatics such as next-generation sequencing, metagenomics, and automating analysesBook Description Handling biological data effectively requires an in-depth knowledge of machine learning techniques and computational skills, along with an understanding of how to use tools such as edgeR and DESeq. With the R Bioinformatics Cookbook, you’ll explore all this and more, tackling common and not-so-common challenges in the bioinformatics domain using real-world examples. This book will use a recipe-based approach to show you how to perform practical research and analysis in computational biology with R. You will learn how to effectively analyze your data with the latest tools in Bioconductor, ggplot, and tidyverse. The book will guide you through the essential tools in Bioconductor to help you understand and carry out protocols in RNAseq, phylogenetics, genomics, and sequence analysis. As you progress, you will get up to speed with how machine learning techniques can be used in the bioinformatics domain. You will gradually develop key computational skills such as creating reusable workflows in R Markdown and packages for code reuse. By the end of this book, you’ll have gained a solid understanding of the most important and widely used techniques in bioinformatic analysis and the tools you need to work with real biological data. What you will learnEmploy Bioconductor to determine differential expressions in RNAseq dataRun SAMtools and develop pipelines to find single nucleotide polymorphisms (SNPs) and IndelsUse ggplot to create and annotate a range of visualizationsQuery external databases with Ensembl to find functional genomics informationExecute large-scale multiple sequence alignment with DECIPHER to perform comparative genomicsUse d3.js and Plotly to create dynamic and interactive web graphicsUse k-nearest neighbors, support vector machines and random forests to find groups and classify dataWho this book is for This book is for bioinformaticians, data analysts, researchers, and R developers who want to address intermediate-to-advanced biological and bioinformatics problems by learning through a recipe-based approach. Working knowledge of R programming language and basic knowledge of bioinformatics are prerequisites.
Book Synopsis Modern Statistics for Modern Biology by : SUSAN. HUBER HOLMES (WOLFGANG.)
Download or read book Modern Statistics for Modern Biology written by SUSAN. HUBER HOLMES (WOLFGANG.) and published by Cambridge University Press. This book was released on 2018 with total page 407 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Computational Genomics with R by : Altuna Akalin
Download or read book Computational Genomics with R written by Altuna Akalin and published by CRC Press. This book was released on 2020-12-16 with total page 463 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational Genomics with R provides a starting point for beginners in genomic data analysis and also guides more advanced practitioners to sophisticated data analysis techniques in genomics. The book covers topics from R programming, to machine learning and statistics, to the latest genomic data analysis techniques. The text provides accessible information and explanations, always with the genomics context in the background. This also contains practical and well-documented examples in R so readers can analyze their data by simply reusing the code presented. As the field of computational genomics is interdisciplinary, it requires different starting points for people with different backgrounds. For example, a biologist might skip sections on basic genome biology and start with R programming, whereas a computer scientist might want to start with genome biology. After reading: You will have the basics of R and be able to dive right into specialized uses of R for computational genomics such as using Bioconductor packages. You will be familiar with statistics, supervised and unsupervised learning techniques that are important in data modeling, and exploratory analysis of high-dimensional data. You will understand genomic intervals and operations on them that are used for tasks such as aligned read counting and genomic feature annotation. You will know the basics of processing and quality checking high-throughput sequencing data. You will be able to do sequence analysis, such as calculating GC content for parts of a genome or finding transcription factor binding sites. You will know about visualization techniques used in genomics, such as heatmaps, meta-gene plots, and genomic track visualization. You will be familiar with analysis of different high-throughput sequencing data sets, such as RNA-seq, ChIP-seq, and BS-seq. You will know basic techniques for integrating and interpreting multi-omics datasets. Altuna Akalin is a group leader and head of the Bioinformatics and Omics Data Science Platform at the Berlin Institute of Medical Systems Biology, Max Delbrück Center, Berlin. He has been developing computational methods for analyzing and integrating large-scale genomics data sets since 2002. He has published an extensive body of work in this area. The framework for this book grew out of the yearly computational genomics courses he has been organizing and teaching since 2015.
Book Synopsis Bioinformatics Data Skills by : Vince Buffalo
Download or read book Bioinformatics Data Skills written by Vince Buffalo and published by "O'Reilly Media, Inc.". This book was released on 2015-07 with total page 538 pages. Available in PDF, EPUB and Kindle. Book excerpt: Learn the data skills necessary for turning large sequencing datasets into reproducible and robust biological findings. With this practical guide, youâ??ll learn how to use freely available open source tools to extract meaning from large complex biological data sets. At no other point in human history has our ability to understand lifeâ??s complexities been so dependent on our skills to work with and analyze data. This intermediate-level book teaches the general computational and data skills you need to analyze biological data. If you have experience with a scripting language like Python, youâ??re ready to get started. Go from handling small problems with messy scripts to tackling large problems with clever methods and tools Process bioinformatics data with powerful Unix pipelines and data tools Learn how to use exploratory data analysis techniques in the R language Use efficient methods to work with genomic range data and range operations Work with common genomics data file formats like FASTA, FASTQ, SAM, and BAM Manage your bioinformatics project with the Git version control system Tackle tedious data processing tasks with with Bash scripts and Makefiles
Book Synopsis A Primer for Computational Biology by : Shawn T. O'Neil
Download or read book A Primer for Computational Biology written by Shawn T. O'Neil and published by . This book was released on 2017-12-21 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Primer for Computational Biology aims to provide life scientists and students the skills necessary for research in a data-rich world. The text covers accessing and using remote servers via the command-line, writing programs and pipelines for data analysis, and provides useful vocabulary for interdisciplinary work. The book is broken into three parts: Introduction to Unix/Linux: The command-line is the "natural environment" of scientific computing, and this part covers a wide range of topics, including logging in, working with files and directories, installing programs and writing scripts, and the powerful "pipe" operator for file and data manipulation. Programming in Python: Python is both a premier language for learning and a common choice in scientific software development. This part covers the basic concepts in programming (data types, if-statements and loops, functions) via examples of DNA-sequence analysis. This part also covers more complex subjects in software development such as objects and classes, modules, and APIs. Programming in R: The R language specializes in statistical data analysis, and is also quite useful for visualizing large datasets. This third part covers the basics of R as a programming language (data types, if-statements, functions, loops and when to use them) as well as techniques for large-scale, multi-test analyses. Other topics include S3 classes and data visualization with ggplot2.
Book Synopsis Bioinformatics Algorithms by : Phillip Compeau
Download or read book Bioinformatics Algorithms written by Phillip Compeau and published by . This book was released on 1986-06 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioinformatics Algorithms: an Active Learning Approach is one of the first textbooks to emerge from the recent Massive Online Open Course (MOOC) revolution. A light-hearted and analogy-filled companion to the authors' acclaimed online course (http://coursera.org/course/bioinformatics), this book presents students with a dynamic approach to learning bioinformatics. It strikes a unique balance between practical challenges in modern biology and fundamental algorithmic ideas, thus capturing the interest of students of biology and computer science students alike.Each chapter begins with a central biological question, such as "Are There Fragile Regions in the Human Genome?" or "Which DNA Patterns Play the Role of Molecular Clocks?" and then steadily develops the algorithmic sophistication required to answer this question. Hundreds of exercises are incorporated directly into the text as soon as they are needed; readers can test their knowledge through automated coding challenges on Rosalind (http://rosalind.info), an online platform for learning bioinformatics.The textbook website (http://bioinformaticsalgorithms.org) directs readers toward additional educational materials, including video lectures and PowerPoint slides.
Book Synopsis Introductory Statistics with R by : Peter Dalgaard
Download or read book Introductory Statistics with R written by Peter Dalgaard and published by Springer Science & Business Media. This book was released on 2008-06-27 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an elementary-level introduction to R, targeting both non-statistician scientists in various fields and students of statistics. The main mode of presentation is via code examples with liberal commenting of the code and the output, from the computational as well as the statistical viewpoint. Brief sections introduce the statistical methods before they are used. A supplementary R package can be downloaded and contains the data sets. All examples are directly runnable and all graphics in the text are generated from the examples. The statistical methodology covered includes statistical standard distributions, one- and two-sample tests with continuous data, regression analysis, one-and two-way analysis of variance, regression analysis, analysis of tabular data, and sample size calculations. In addition, the last four chapters contain introductions to multiple linear regression analysis, linear models in general, logistic regression, and survival analysis.
Book Synopsis R for Data Science by : Hadley Wickham
Download or read book R for Data Science written by Hadley Wickham and published by "O'Reilly Media, Inc.". This book was released on 2016-12-12 with total page 521 pages. Available in PDF, EPUB and Kindle. Book excerpt: Learn how to use R to turn raw data into insight, knowledge, and understanding. This book introduces you to R, RStudio, and the tidyverse, a collection of R packages designed to work together to make data science fast, fluent, and fun. Suitable for readers with no previous programming experience, R for Data Science is designed to get you doing data science as quickly as possible. Authors Hadley Wickham and Garrett Grolemund guide you through the steps of importing, wrangling, exploring, and modeling your data and communicating the results. You'll get a complete, big-picture understanding of the data science cycle, along with basic tools you need to manage the details. Each section of the book is paired with exercises to help you practice what you've learned along the way. You'll learn how to: Wrangle—transform your datasets into a form convenient for analysis Program—learn powerful R tools for solving data problems with greater clarity and ease Explore—examine your data, generate hypotheses, and quickly test them Model—provide a low-dimensional summary that captures true "signals" in your dataset Communicate—learn R Markdown for integrating prose, code, and results
Book Synopsis Metaprogramming in R by : Thomas Mailund
Download or read book Metaprogramming in R written by Thomas Mailund and published by Apress. This book was released on 2017-06-01 with total page 106 pages. Available in PDF, EPUB and Kindle. Book excerpt: Learn how to manipulate functions and expressions to modify how the R language interprets itself. This book is an introduction to metaprogramming in the R language, so you will write programs to manipulate other programs. Metaprogramming in R shows you how to treat code as data that you can generate, analyze, or modify. R is a very high-level language where all operations are functions and all functions are data that can be manipulated. This book shows you how to leverage R's natural flexibility in how function calls and expressions are evaluated, to create small domain-specific languages to extend R within the R language itself. What You'll Learn Find out about the anatomy of a function in R Look inside a function call Work with R expressions and environments Manipulate expressions in R Use substitutions Who This Book Is For Those with at least some experience with R and certainly for those with experience in other programming languages.
Book Synopsis Python for Biologists by : Martin Jones
Download or read book Python for Biologists written by Martin Jones and published by Createspace Independent Publishing Platform. This book was released on 2013 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: Python for biologists is a complete programming course for beginners that will give you the skills you need to tackle common biological and bioinformatics problems.
Book Synopsis Bioinformatics with R Cookbook by : Paurush Praveen
Download or read book Bioinformatics with R Cookbook written by Paurush Praveen and published by . This book was released on 2014 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is an easy-to-follow, stepwise guide to handle real life Bioinformatics problems. Each recipe comes with a detailed explanation to the solution steps. A systematic approach, coupled with lots of illustrations, tips, and tricks will help you as a reader grasp even the trickiest of concepts without difficulty. This book is ideal for computational biologists and bioinformaticians with basic knowledge of R programming, bioinformatics and statistics. If you want to understand various critical concepts needed to develop your computational models in Bioinformatics, then this book is for you.
Book Synopsis R for Medicine and Biology by : Paul D. Lewis
Download or read book R for Medicine and Biology written by Paul D. Lewis and published by Jones & Bartlett Learning. This book was released on 2009-05-08 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: R is quickly becoming the number one choice for users in the fields of biology, medicine, and bioinformatics as their main means of storing, processing, sharing, and analyzing biomedical data. R for Medicine and Biology is a step-by-step guide through the use of the statistical environment R, as used in a biomedical domain. Ideal for healthcare professionals, scientists, informaticists, and statistical experts, this resource will provide even the novice programmer with the tools necessary to process and analyze their data using the R environment. Introductory chapters guide readers in how to obtain, install, and become familiar with R and provide a clear introduction to the programming language using numerous worked examples. Later chapters outline how R can be used, not just for biomedical data analysis, but also as an environment for the processing, storing, reporting, and sharing of data and results. The remainder of the book explores areas of R application to common domains of biomedical informatics, including imaging, statistical analysis, data mining/modeling, pathology informatics, epidemiology, clinical trials, and metadata usage. R for Medicine and Biology will provide you with a single desk reference for the R environment and its many capabilities.
Book Synopsis Mastering Machine Learning with R by : Cory Lesmeister
Download or read book Mastering Machine Learning with R written by Cory Lesmeister and published by Packt Publishing Ltd. This book was released on 2015-10-28 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Master machine learning techniques with R to deliver insights for complex projects About This Book Get to grips with the application of Machine Learning methods using an extensive set of R packages Understand the benefits and potential pitfalls of using machine learning methods Implement the numerous powerful features offered by R with this comprehensive guide to building an independent R-based ML system Who This Book Is For If you want to learn how to use R's machine learning capabilities to solve complex business problems, then this book is for you. Some experience with R and a working knowledge of basic statistical or machine learning will prove helpful. What You Will Learn Gain deep insights to learn the applications of machine learning tools to the industry Manipulate data in R efficiently to prepare it for analysis Master the skill of recognizing techniques for effective visualization of data Understand why and how to create test and training data sets for analysis Familiarize yourself with fundamental learning methods such as linear and logistic regression Comprehend advanced learning methods such as support vector machines Realize why and how to apply unsupervised learning methods In Detail Machine learning is a field of Artificial Intelligence to build systems that learn from data. Given the growing prominence of R—a cross-platform, zero-cost statistical programming environment—there has never been a better time to start applying machine learning to your data. The book starts with introduction to Cross-Industry Standard Process for Data Mining. It takes you through Multivariate Regression in detail. Moving on, you will also address Classification and Regression trees. You will learn a couple of “Unsupervised techniques”. Finally, the book will walk you through text analysis and time series. The book will deliver practical and real-world solutions to problems and variety of tasks such as complex recommendation systems. By the end of this book, you will gain expertise in performing R machine learning and will be able to build complex ML projects using R and its packages. Style and approach This is a book explains complicated concepts with easy to follow theory and real-world, practical applications. It demonstrates the power of R and machine learning extensively while highlighting the constraints.
Book Synopsis Python Programming for Biology by : Tim J. Stevens
Download or read book Python Programming for Biology written by Tim J. Stevens and published by Cambridge University Press. This book was released on 2015-02-12 with total page 721 pages. Available in PDF, EPUB and Kindle. Book excerpt: Do you have a biological question that could be readily answered by computational techniques, but little experience in programming? Do you want to learn more about the core techniques used in computational biology and bioinformatics? Written in an accessible style, this guide provides a foundation for both newcomers to computer programming and those interested in learning more about computational biology. The chapters guide the reader through: a complete beginners' course to programming in Python, with an introduction to computing jargon; descriptions of core bioinformatics methods with working Python examples; scientific computing techniques, including image analysis, statistics and machine learning. This book also functions as a language reference written in straightforward English, covering the most common Python language elements and a glossary of computing and biological terms. This title will teach undergraduates, postgraduates and professionals working in the life sciences how to program with Python, a powerful, flexible and easy-to-use language.
