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Quantitative Neuroscience
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Book Synopsis Quantitative Neuroscience by : Panos M. Pardalos
Download or read book Quantitative Neuroscience written by Panos M. Pardalos and published by Springer Science & Business Media. This book was released on 2013-12-01 with total page 263 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in the field of signal processing, nonlinear dynamics, statistics, and optimization theory, combined with marked improvement in instrumenta tion and development of computers systems, have made it possible to apply the power of mathematics to the task of understanding the human brain. This verita ble revolution already has resulted in widespread availability of high resolution neuroimaging devices in clinical as well as research settings. Breakthroughs in functional imaging are not far behind. Mathematical tech niques developed for the study of complex nonlinear systems and chaos already are being used to explore the complex nonlinear dynamics of human brain phys iology. Global optimization is being applied to data mining expeditions in an effort to find knowledge in the vast amount of information being generated by neuroimaging and neurophysiological investigations. These breakthroughs in the ability to obtain, store and analyze large datasets offer, for the first time, exciting opportunities to explore the mechanisms underlying normal brain func tion as well as the affects of diseases such as epilepsy, sleep disorders, movement disorders, and cognitive disorders that affect millions of people every year. Ap plication of these powerful tools to the study of the human brain requires, by necessity, collaboration among scientists, engineers, neurobiologists and clini cians. Each discipline brings to the table unique knowledge, unique approaches to problem solving, and a unique language.
Book Synopsis Quantitative Neuroscience by : Panos M. Pardalos
Download or read book Quantitative Neuroscience written by Panos M. Pardalos and published by Springer Science & Business Media. This book was released on 2004-01-31 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in the field of signal processing, nonlinear dynamics, statistics, and optimization theory, combined with marked improvement in instrumenta tion and development of computers systems, have made it possible to apply the power of mathematics to the task of understanding the human brain. This verita ble revolution already has resulted in widespread availability of high resolution neuroimaging devices in clinical as well as research settings. Breakthroughs in functional imaging are not far behind. Mathematical tech niques developed for the study of complex nonlinear systems and chaos already are being used to explore the complex nonlinear dynamics of human brain phys iology. Global optimization is being applied to data mining expeditions in an effort to find knowledge in the vast amount of information being generated by neuroimaging and neurophysiological investigations. These breakthroughs in the ability to obtain, store and analyze large datasets offer, for the first time, exciting opportunities to explore the mechanisms underlying normal brain func tion as well as the affects of diseases such as epilepsy, sleep disorders, movement disorders, and cognitive disorders that affect millions of people every year. Ap plication of these powerful tools to the study of the human brain requires, by necessity, collaboration among scientists, engineers, neurobiologists and clini cians. Each discipline brings to the table unique knowledge, unique approaches to problem solving, and a unique language.
Book Synopsis An Introductory Course in Computational Neuroscience by : Paul Miller
Download or read book An Introductory Course in Computational Neuroscience written by Paul Miller and published by MIT Press. This book was released on 2018-10-09 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: A textbook for students with limited background in mathematics and computer coding, emphasizing computer tutorials that guide readers in producing models of neural behavior. This introductory text teaches students to understand, simulate, and analyze the complex behaviors of individual neurons and brain circuits. It is built around computer tutorials that guide students in producing models of neural behavior, with the associated Matlab code freely available online. From these models students learn how individual neurons function and how, when connected, neurons cooperate in a circuit. The book demonstrates through simulated models how oscillations, multistability, post-stimulus rebounds, and chaos can arise within either single neurons or circuits, and it explores their roles in the brain. The book first presents essential background in neuroscience, physics, mathematics, and Matlab, with explanations illustrated by many example problems. Subsequent chapters cover the neuron and spike production; single spike trains and the underlying cognitive processes; conductance-based models; the simulation of synaptic connections; firing-rate models of large-scale circuit operation; dynamical systems and their components; synaptic plasticity; and techniques for analysis of neuron population datasets, including principal components analysis, hidden Markov modeling, and Bayesian decoding. Accessible to undergraduates in life sciences with limited background in mathematics and computer coding, the book can be used in a “flipped” or “inverted” teaching approach, with class time devoted to hands-on work on the computer tutorials. It can also be a resource for graduate students in the life sciences who wish to gain computing skills and a deeper knowledge of neural function and neural circuits.
Book Synopsis Quantitative Methods in Neuroscience by : Stephen M. Evans
Download or read book Quantitative Methods in Neuroscience written by Stephen M. Evans and published by . This book was released on 2004 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stereology is a valuable tool for neuroscientists, allowing them to obtain 3-Dimensional information from 2-Dimensional measurements made on appropriately sampled sections (usually obtained from histological sections or MRI/CT/PET scans). This 3-D information is invaluable in correlatingstructural/functional relationships in the pursuit of far greater understanding of the function of the central nervous system. However, in carrying out such measurements, often based on limited data sets, there is a risk of experimenter bias. An important feature of modern design based stereology isto be aware of potential sources of bias and eliminate them during the data collection. With many of the major neuroscience journals now insisting that quantitative data be presented, there is a greater need than ever for neuroscientists to understand the theory and practice behind quantitativemethods, such as those offered by stereology. Quantitative Methods in Neuroscience is a cookbook of stereological methods written especially for neuroscientists. It provides clear and accessible advice about when and when not to use stereology. Throughout the book, the emphasis is on practical guidance, rather than discussions and formulae.Written by leading scientists in the field of stereology, with a Foreword by D.C. Sterio, the book will be a valuable introduction to these methods for neuroscientists, and all those involved in development of new drug programmes.
Book Synopsis Computational Neuroscience and Cognitive Modelling by : Britt Anderson
Download or read book Computational Neuroscience and Cognitive Modelling written by Britt Anderson and published by SAGE. This book was released on 2014-01-08 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: "For the neuroscientist or psychologist who cringes at the sight of mathematical formulae and whose eyes glaze over at terms like differential equations, linear algebra, vectors, matrices, Bayes’ rule, and Boolean logic, this book just might be the therapy needed." - Anjan Chatterjee, Professor of Neurology, University of Pennsylvania "Anderson provides a gentle introduction to computational aspects of psychological science, managing to respect the reader’s intelligence while also being completely unintimidating. Using carefully-selected computational demonstrations, he guides students through a wide array of important approaches and tools, with little in the way of prerequisites...I recommend it with enthusiasm." - Asohan Amarasingham, The City University of New York This unique, self-contained and accessible textbook provides an introduction to computational modelling neuroscience accessible to readers with little or no background in computing or mathematics. Organized into thematic sections, the book spans from modelling integrate and firing neurons to playing the game Rock, Paper, Scissors in ACT-R. This non-technical guide shows how basic knowledge and modern computers can be combined for interesting simulations, progressing from early exercises utilizing spreadsheets, to simple programs in Python. Key Features include: Interleaved chapters that show how traditional computing constructs are simply disguised versions of the spread sheet methods. Mathematical facts and notation needed to understand the modelling methods are presented at their most basic and are interleaved with biographical and historical notes for contex. Numerous worked examples to demonstrate the themes and procedures of cognitive modelling. An excellent text for postgraduate students taking courses in research methods, computational neuroscience, computational modelling, cognitive science and neuroscience. It will be especially valuable to psychology students.
Book Synopsis Computational Neuroscience for Advancing Artificial Intelligence: Models, Methods and Applications by : Alonso, Eduardo
Download or read book Computational Neuroscience for Advancing Artificial Intelligence: Models, Methods and Applications written by Alonso, Eduardo and published by IGI Global. This book was released on 2010-11-30 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This book argues that computational models in behavioral neuroscience must be taken with caution, and advocates for the study of mathematical models of existing theories as complementary to neuro-psychological models and computational models"--
Book Synopsis Computational Vision by : Hanspeter A. Mallot
Download or read book Computational Vision written by Hanspeter A. Mallot and published by MIT Press. This book was released on 2000 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text provides an introduction to computational aspects of early vision, in particular, color, stereo, and visual navigation. It integrates approaches from psychophysics and quantitative neurobiology, as well as theories and algorithms from machine vision and photogrammetry. When presenting mathematical material, it uses detailed verbal descriptions and illustrations to clarify complex points. The text is suitable for upper-level students in neuroscience, biology, and psychology who have basic mathematical skills and are interested in studying the mathematical modeling of perception.
Book Synopsis Dynamical Systems in Neuroscience by : Eugene M. Izhikevich
Download or read book Dynamical Systems in Neuroscience written by Eugene M. Izhikevich and published by MIT Press. This book was released on 2010-01-22 with total page 459 pages. Available in PDF, EPUB and Kindle. Book excerpt: Explains the relationship of electrophysiology, nonlinear dynamics, and the computational properties of neurons, with each concept presented in terms of both neuroscience and mathematics and illustrated using geometrical intuition. In order to model neuronal behavior or to interpret the results of modeling studies, neuroscientists must call upon methods of nonlinear dynamics. This book offers an introduction to nonlinear dynamical systems theory for researchers and graduate students in neuroscience. It also provides an overview of neuroscience for mathematicians who want to learn the basic facts of electrophysiology. Dynamical Systems in Neuroscience presents a systematic study of the relationship of electrophysiology, nonlinear dynamics, and computational properties of neurons. It emphasizes that information processing in the brain depends not only on the electrophysiological properties of neurons but also on their dynamical properties. The book introduces dynamical systems, starting with one- and two-dimensional Hodgkin-Huxley-type models and continuing to a description of bursting systems. Each chapter proceeds from the simple to the complex, and provides sample problems at the end. The book explains all necessary mathematical concepts using geometrical intuition; it includes many figures and few equations, making it especially suitable for non-mathematicians. Each concept is presented in terms of both neuroscience and mathematics, providing a link between the two disciplines. Nonlinear dynamical systems theory is at the core of computational neuroscience research, but it is not a standard part of the graduate neuroscience curriculum—or taught by math or physics department in a way that is suitable for students of biology. This book offers neuroscience students and researchers a comprehensive account of concepts and methods increasingly used in computational neuroscience. An additional chapter on synchronization, with more advanced material, can be found at the author's website, www.izhikevich.com.
Book Synopsis Encyclopedia of Computational Neuroscience by : Dieter Jaeger
Download or read book Encyclopedia of Computational Neuroscience written by Dieter Jaeger and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Advanced Data Analysis in Neuroscience by : Daniel Durstewitz
Download or read book Advanced Data Analysis in Neuroscience written by Daniel Durstewitz and published by Springer. This book was released on 2017-09-15 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is intended for use in advanced graduate courses in statistics / machine learning, as well as for all experimental neuroscientists seeking to understand statistical methods at a deeper level, and theoretical neuroscientists with a limited background in statistics. It reviews almost all areas of applied statistics, from basic statistical estimation and test theory, linear and nonlinear approaches for regression and classification, to model selection and methods for dimensionality reduction, density estimation and unsupervised clustering. Its focus, however, is linear and nonlinear time series analysis from a dynamical systems perspective, based on which it aims to convey an understanding also of the dynamical mechanisms that could have generated observed time series. Further, it integrates computational modeling of behavioral and neural dynamics with statistical estimation and hypothesis testing. This way computational models in neuroscience are not only explanatory frameworks, but become powerful, quantitative data-analytical tools in themselves that enable researchers to look beyond the data surface and unravel underlying mechanisms. Interactive examples of most methods are provided through a package of MatLab routines, encouraging a playful approach to the subject, and providing readers with a better feel for the practical aspects of the methods covered. "Computational neuroscience is essential for integrating and providing a basis for understanding the myriads of remarkable laboratory data on nervous system functions. Daniel Durstewitz has excellently covered the breadth of computational neuroscience from statistical interpretations of data to biophysically based modeling of the neurobiological sources of those data. His presentation is clear, pedagogically sound, and readily useable by experts and beginners alike. It is a pleasure to recommend this very well crafted discussion to experimental neuroscientists as well as mathematically well versed Physicists. The book acts as a window to the issues, to the questions, and to the tools for finding the answers to interesting inquiries about brains and how they function." Henry D. I. Abarbanel Physics and Scripps Institution of Oceanography, University of California, San Diego “This book delivers a clear and thorough introduction to sophisticated analysis approaches useful in computational neuroscience. The models described and the examples provided will help readers develop critical intuitions into what the methods reveal about data. The overall approach of the book reflects the extensive experience Prof. Durstewitz has developed as a leading practitioner of computational neuroscience. “ Bruno B. Averbeck
Book Synopsis Computational Neuroscience by : Erik De Schutter
Download or read book Computational Neuroscience written by Erik De Schutter and published by CRC Press. This book was released on 2000-11-22 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Designed primarily as an introduction to realistic modeling methods, Computational Neuroscience: Realistic Modeling for Experimentalists focuses on methodological approaches, selecting appropriate methods, and identifying potential pitfalls. The author addresses varying levels of complexity, from molecular interactions within single neurons to the
Book Synopsis Neural Engineering by : Chris Eliasmith
Download or read book Neural Engineering written by Chris Eliasmith and published by MIT Press. This book was released on 2003 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: A synthesis of current approaches to adapting engineering tools to the study of neurobiological systems.
Author :Wanpracha Chaovalitwongse Publisher :Springer Science & Business Media ISBN 13 :0387886303 Total Pages :330 pages Book Rating :4.3/5 (878 download)
Book Synopsis Computational Neuroscience by : Wanpracha Chaovalitwongse
Download or read book Computational Neuroscience written by Wanpracha Chaovalitwongse and published by Springer Science & Business Media. This book was released on 2010-07-03 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume includes contributions from diverse disciplines including electrical engineering, biomedical engineering, industrial engineering, and medicine, bridging a vital gap between the mathematical sciences and neuroscience research. Covering a wide range of research topics, this volume demonstrates how various methods from data mining, signal processing, optimization and cutting-edge medical techniques can be used to tackle the most challenging problems in modern neuroscience.
Book Synopsis Computational Neuroscience by : James M. Bower
Download or read book Computational Neuroscience written by James M. Bower and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 897 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume includes papers presented at the Fifth Annual Computational Neurosci ence meeting (CNS*96) held in Boston, Massachusetts, July 14 - 17, 1996. This collection includes 148 of the 234 papers presented at the meeting. Acceptance for mceting presenta tion was based on the peer review of preliminary papers originally submitted in May of 1996. The papers in this volume represent final versions of this work submitted in January of 1997. As represented by this volume, computational neuroscience continues to expand in quality, size and breadth of focus as increasing numbers of neuroscientists are taking a computational approach to understanding nervous system function. Defining computa tional neuroscience as the exploration of how brains compute, it is clear that there is al most no subject or area of modern neuroscience research that is not appropriate for computational studies. The CNS meetings as well as this volume reflect this scope and di versity.
Download or read book Computational Neuroscience written by and published by Academic Press. This book was released on 2014-02-18 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: Progress in Molecular Biology and Translational Science provides a forum for discussion of new discoveries, approaches, and ideas in molecular biology. It contains contributions from leaders in their fields and abundant references. This volume brings together different aspects of, and approaches to, molecular and multi-scale modeling, with applications to a diverse range of neurological diseases. Mathematical and computational modeling offers a powerful approach for examining the interaction between molecular pathways and ionic channels in producing neuron electrical activity. It is well accepted that non-linear interactions among diverse ionic channels can produce unexpected neuron behavior and hinder a deep understanding of how ion channel mutations bring about abnormal behavior and disease. Interactions with the diverse signaling pathways activated by G protein coupled receptors or calcium influx adds an additional level of complexity. Modeling is an approach to integrate myriad data sources into a cohesive and quantitative model in order to evaluate hypotheses about neuron function. In particular, a validated model developed using in vitro data allows simulations of the response to in vivo like spatio-temporal patterns of synaptic input. Incorporating molecular signaling pathways into an electrical model, allows a greater range of models to be developed, ones that can predict the response to pharmaceuticals, many of which target neuromodulator pathways. Contributions from leading authorities Informs and updates on all the latest developments in the field
Book Synopsis Computational Neuroscience by : Jianfeng Feng
Download or read book Computational Neuroscience written by Jianfeng Feng and published by CRC Press. This book was released on 2003-10-20 with total page 649 pages. Available in PDF, EPUB and Kindle. Book excerpt: How does the brain work? After a century of research, we still lack a coherent view of how neurons process signals and control our activities. But as the field of computational neuroscience continues to evolve, we find that it provides a theoretical foundation and a set of technological approaches that can significantly enhance our understanding.
Book Synopsis Computational Neuroscience: Trends in Research 2004 by : E. De Schutter
Download or read book Computational Neuroscience: Trends in Research 2004 written by E. De Schutter and published by Elsevier. This book was released on 2004-06-26 with total page 1260 pages. Available in PDF, EPUB and Kindle. Book excerpt: The CNS meetings bring together computational neuroscientists representing many different fields and backgrounds as well as many different experimental preparations and theoretical approaches. The papers published here range from pure experimental neurobiology, to neuro-ethology, mathematics, physics, and engineering. In all cases the research described is focused on understanding how nervous systems compute. The actual subjects of the research include a highly diverse number of preparations, modeling approaches and analysis techniques. Accordingly, this volume reflects the breadth and depth of current research in computational neuroscience taking place throughout the world.
