Read Books Online and Download eBooks, EPub, PDF, Mobi, Kindle, Text Full Free.
Quantitative Mri Of The Spinal Cord
Download Quantitative Mri Of The Spinal Cord full books in PDF, epub, and Kindle. Read online Quantitative Mri Of The Spinal Cord ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Book Synopsis Quantitative MRI of the Spinal Cord by : Julien Cohen-Adad
Download or read book Quantitative MRI of the Spinal Cord written by Julien Cohen-Adad and published by Academic Press. This book was released on 2014-01-16 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: Quantitative MRI of the Spinal Cord is the first book focused on quantitative MRI techniques with specific application to the human spinal cord. This work includes coverage of diffusion-weighted imaging, magnetization transfer imaging, relaxometry, functional MRI, and spectroscopy. Although these methods have been successfully used in the brain for the past 20 years, their application in the spinal cord remains problematic due to important acquisition challenges (such as small cross-sectional size, motion, and susceptibility artifacts). To date, there is no consensus on how to apply these techniques; this book reviews and synthesizes state-of-the-art methods so users can successfully apply them to the spinal cord. Quantitative MRI of the Spinal Cord introduces the theory behind each quantitative technique, reviews each theory’s applications in the human spinal cord and describes its pros and cons, and suggests a simple protocol for applying each quantitative technique to the spinal cord. Chapters authored by international experts in the field of MRI of the spinal cord Contains “cooking recipes —examples of imaging parameters for each quantitative technique—designed to aid researchers and clinicians in using them in practice Ideal for clinical settings
Book Synopsis High Resolution Quantitative MRI in a Non-Surgical Model of Spinal Cord Injury by : Wendy K. Oakden
Download or read book High Resolution Quantitative MRI in a Non-Surgical Model of Spinal Cord Injury written by Wendy K. Oakden and published by . This book was released on 2015 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Magnetic resonance imaging (MRI) is very sensitive to the presence of damage resulting from injury or disease, but often lacks specificity. Quantitative MRI can significantly increase the specificity in the presence of pathology but must be validated, often using an animal model, for each type of injury or disease. In the case of spinal cord injury (SCI) most models are difficult to image, either due to the location of the injury, or as a result of damage to surrounding tissues resulting from invasive surgical procedures. This thesis describes a non-surgical model of rat SCI which uses MR guided focused ultrasound and microbubbles to create an injury the cervical spinal cord which is optimal for performing quantitative MRI, and compares it with other models of SCI using MRI, histology, and immunohistochemistry. It also describes the difficulties encountered when implementing the quantitative T2 (qT2) MR sequence at the very high resolution required to image the rat spinal cord, the limitations on the qT2 sequence due to the presence of diffusion, and how the effects of diffusion were minimized. Using the new SCI model and qT2 sequence, qT2 and diffusion data were acquired at 24 hours, 1 week, and 2 weeks following SCI, and the quantitative MRI parameters were correlated with histology. The increased specificity gained using quantitative MRI will increase the information available at each timepoint, reducing both the variability and cost of longitudinal studies aimed at developing treatments for SCI.
Book Synopsis Quantitative MRI for Measuring Myelin Content in Human Spinal Cord by : Marco Battiston
Download or read book Quantitative MRI for Measuring Myelin Content in Human Spinal Cord written by Marco Battiston and published by . This book was released on 2018 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis MULTIPARAMETRIC MRI OF THE PEDIATRIC SPINAL CORD by : Shiva Shahrampour
Download or read book MULTIPARAMETRIC MRI OF THE PEDIATRIC SPINAL CORD written by Shiva Shahrampour and published by . This book was released on 2023 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Quantitative magnetic resonance imaging (MRI) measurements of the pediatric spinal cord is important for both diagnostic and treatment planning. In recent years several quantitative MRI (qMRI) techniques that have been developed and tested to measure functional and structural information of the spinal cord tissue and microstructure. Several of the existing structural and functional imaging biomarkers (i.e., diffusion tensor imaging (DTI)) have demonstrated potential for providing microstructural information about the spinal cord. However, due to the lack of a standard anatomical template of the pediatric spinal cord, quantification of the spinal cord tissue has been challenging. Therefore, one of the goals of this work is to develop and test tools for quantification as well as the creation of a standard structural template of the typically developing (TD) pediatric spinal cord. This will allow automated measurement of normative values of the spinal cord cross-sectional area (SCCSA) at various levels of the spinal cord. Furthermore, to examine the white matter (WM) microstructure of the pediatric cord we developed a processing pipeline for the atlas-based generation of TD pediatric spinal cord WM tracts. This will facilitate the measurements of normative diffusion values for various WM tracts.A group of 30 TD subjects (age range of 6-17 years old (12.38 ±2.81)), who had no evidence of spinal cord injury or pathology were recruited. We utilized a multiparametric MRI protocol, including high-resolution T2-w structural and diffusion-weighted MRI images to scan the subjects on a 3T MRI scanner. The diffusion data were acquired using a novel iFOV DTI sequence. For quantification, a post-processing pipeline was utilized to generate the structural pediatric template. Next, WM tracts were generated using an atlas-based approach, and diffusion metrics (FA, MD, RD and AD) were quantified in 34 tracts identified in the processing pipeline. Normative SCCSA and DTI diffusion indices were generated for the TD population. Lastly, we demonstrated that DTI indices (i.e. FA) can be a predictive measure of components of the clinical test for spinal cord injury, as well as an indicator of the white matter tracts integrity. Therefore, in the final step of this work, we expanded our quantitative analysis to look at the microstructural and macrostructural changes in 15 children with chronic spinal cord injury (SCI) (AIS A-D, mean age of 12.8 ± 3.1 years). This included measurements of SCCSA, diffusion metrics and T2* WM/GM ratio of various white matter tracts in the patient population. We also examined the relationships between all the metrics and the ISNCSCI clinical scores in SCI subjects. We then compared these measurements between the TD and SCI patients to evaluate the diagnostic utility of these techniques and biomarkers. Statistically significant difference was observed between the two populations in the studied metrics. The results show that the proposed techniques may have the potential to be used as surrogate biomarkers for the quantification of the injured spinal cord. Keywords: diffusion tensor imaging, typically developing, spinal cord injury, spinal cord cross-sectional area, fractional anisotropy, mean diffusivity, axial diffusivity, radial diffusivity.
Book Synopsis Quantitative Magnetic Resonance Imaging by : Nicole Seiberlich
Download or read book Quantitative Magnetic Resonance Imaging written by Nicole Seiberlich and published by Academic Press. This book was released on 2020-11-18 with total page 1094 pages. Available in PDF, EPUB and Kindle. Book excerpt: Quantitative Magnetic Resonance Imaging is a ‘go-to’ reference for methods and applications of quantitative magnetic resonance imaging, with specific sections on Relaxometry, Perfusion, and Diffusion. Each section will start with an explanation of the basic techniques for mapping the tissue property in question, including a description of the challenges that arise when using these basic approaches. For properties which can be measured in multiple ways, each of these basic methods will be described in separate chapters. Following the basics, a chapter in each section presents more advanced and recently proposed techniques for quantitative tissue property mapping, with a concluding chapter on clinical applications. The reader will learn: The basic physics behind tissue property mapping How to implement basic pulse sequences for the quantitative measurement of tissue properties The strengths and limitations to the basic and more rapid methods for mapping the magnetic relaxation properties T1, T2, and T2* The pros and cons for different approaches to mapping perfusion The methods of Diffusion-weighted imaging and how this approach can be used to generate diffusion tensor maps and more complex representations of diffusion How flow, magneto-electric tissue property, fat fraction, exchange, elastography, and temperature mapping are performed How fast imaging approaches including parallel imaging, compressed sensing, and Magnetic Resonance Fingerprinting can be used to accelerate or improve tissue property mapping schemes How tissue property mapping is used clinically in different organs Structured to cater for MRI researchers and graduate students with a wide variety of backgrounds Explains basic methods for quantitatively measuring tissue properties with MRI - including T1, T2, perfusion, diffusion, fat and iron fraction, elastography, flow, susceptibility - enabling the implementation of pulse sequences to perform measurements Shows the limitations of the techniques and explains the challenges to the clinical adoption of these traditional methods, presenting the latest research in rapid quantitative imaging which has the possibility to tackle these challenges Each section contains a chapter explaining the basics of novel ideas for quantitative mapping, such as compressed sensing and Magnetic Resonance Fingerprinting-based approaches
Book Synopsis Multiparametric Quantitative MRI of the Cervical Spinal Cord to Measure Microstructure and Tissue Injury by : Allan Russell Martin
Download or read book Multiparametric Quantitative MRI of the Cervical Spinal Cord to Measure Microstructure and Tissue Injury written by Allan Russell Martin and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: An array of spinal cord (SC) quantitative MRI (qMRI) techniques can measure aspects of microstructure and tissue injury. This research develops a clinically feasible multiparametric MRI protocol, including diffusion tensor imaging (DTI) fractional anisotropy (FA), magnetization transfer ratio (MTR), and measurement of SC cross-sectional area (CSA). A novel biomarker of white matter (WM) injury is also introduced, normalizing T2*WI WM signal intensity by grey matter (T2*WI WM/GM). A study of 40 healthy subjects establishes methods, normalization procedures, normative values, and reliability. 58 patients with degenerative cervical myelopathy (DCM) are studied, showing significant differences in 10 metrics. Combining these measures using multivariate methods overcomes the limitations of each technique, achieving good diagnostic accuracy and clinical correlation. T2*WI WM/GM shows strong potential as a novel biomarker, comparing favourably with established biomarkers FA and MTR. Our study of healthy subjects identifies an alarming rate of asymptomatic SC compression (ASCC) at 50%. Objective criteria and automated shape analysis are developed to create a new definition of SC compression, and qMRI demonstrates significant tissue injury in this group. This finding suggests the potential for pre-symptomatic diagnosis of DCM and other spinal pathologies. Finally, a longitudinal study compares multiparametric qMRI with clinical measures for monitoring disease progression in DCM, indicating that modified Japanese Orthopedic Association (mJOA) score is insensitive to detect progression, whereas qMRI showed tissue progression more often than comprehensive clinical assessments. These results suggest that natural history studies employing mJOA underestimate progression, due to neuroplasticity and behavioural adaptation. Combined qMRI and clinical data are now being used to inform surgical decision-making for individual patients. Reliable multiparametric assessment of SC microstructure is possible using clinically suitable methods. This approach shows strong clinical utility for individual patients, including good diagnostic accuracy, correlations with impairment, detection of tissue injury in asymptomatic individuals, and detection of progressive tissue injury in DCM patients.
Book Synopsis Multi-parametric Magnetic Resonance Imaging of the Spinal Cord at 9.4T by : Tung-Lin Wu
Download or read book Multi-parametric Magnetic Resonance Imaging of the Spinal Cord at 9.4T written by Tung-Lin Wu and published by . This book was released on 2018 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Quantitative MRI of the Brain by : Mara Cercignani
Download or read book Quantitative MRI of the Brain written by Mara Cercignani and published by CRC Press. This book was released on 2018-01-12 with total page 782 pages. Available in PDF, EPUB and Kindle. Book excerpt: Building on the success of the first edition of this book, the winner of the 2004 British Medical Association Radiology Medical Book Competition, Quantitative MRI of the Brain: Principles of Physical Measurement gives a unique view on how to use an MRI machine in a new way. Used as a scientific instrument it can make measurements of a myriad of physical and biological quantities in the human brain and body. For each small tissue voxel, non-invasive information monitors how tissue changes with disease and responds to treatment. The book opens with a detailed exposition of the principles of good practice in quantification, including fundamental concepts, quality assurance, MR data collection and analysis and improved study statistical power through minimised instrumental variation. There follow chapters on 14 specific groups of quantities: proton density, T1, T2, T2*, diffusion, advanced diffusion, magnetisation transfer, CEST, 1H and multi-nuclear spectroscopy, DCE-MRI, quantitative fMRI, arterial spin-labelling and image analysis, and finally a chapter on the future of quantification. The physical principles behind each quantity are stated, followed by its biological significance. Practical techniques for measurement are given, along with pitfalls and examples of clinical applications. This second edition of this indispensable 'how to' manual of quantitative MR shows the MRI physicist and research clinician how to implement these techniques on an MRI scanner to understand more about the biological processes in the patient and physiological changes in healthy controls. Although focussed on the brain, most techniques are applicable to characterising tissue in the whole body. This book is essential reading for anyone who wants to use the gamut of modern quantitative MRI methods to measure the effects of disease, its progression, and its response to treatment. Features: The first edition was awarded the book prize for Radiology by the British Medical Association in 2004 Written by an authority in the field: Professor Tofts has an international reputation for quantification in MRI Gives specific ‘how to’ information for implementation of MRI measurement sequence techniques
Book Synopsis Quantitative MRI of the Brain by : Paul Tofts
Download or read book Quantitative MRI of the Brain written by Paul Tofts and published by John Wiley & Sons. This book was released on 2003 with total page 678 pages. Available in PDF, EPUB and Kindle. Book excerpt: A 'how to' manual of quantitative MR, essential for anyone who wants to use the gamut of modern quantitative methods to measure the effects of neurological diseases, its progression and its response to treatment. It is also designed for research-minded radiologists, neurologists and MRI physicists who are considering undertaking quantitative work, as well as those already in the field.
Book Synopsis Development and Application of Quantitative MRI Methods for Assessing White Matter Integrity in the Mouse Brain by : Jonathan Thiessen
Download or read book Development and Application of Quantitative MRI Methods for Assessing White Matter Integrity in the Mouse Brain written by Jonathan Thiessen and published by . This book was released on 2012 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Magnetic Resonance Imaging of the Brain and Spine by : Scott W. Atlas
Download or read book Magnetic Resonance Imaging of the Brain and Spine written by Scott W. Atlas and published by Lippincott Williams & Wilkins. This book was released on 2009 with total page 1976 pages. Available in PDF, EPUB and Kindle. Book excerpt: Established as the leading textbook on imaging diagnosis of brain and spine disorders, Magnetic Resonance Imaging of the Brain and Spine is now in its Fourth Edition. This thoroughly updated two-volume reference delivers cutting-edge information on nearly every aspect of clinical neuroradiology. Expert neuroradiologists, innovative renowned MRI physicists, and experienced leading clinical neurospecialists from all over the world show how to generate state-of-the-art images and define diagnoses from crucial clinical/pathologic MR imaging correlations for neurologic, neurosurgical, and psychiatric diseases spanning fetal CNS anomalies to disorders of the aging brain. Highlights of this edition include over 6,800 images of remarkable quality, more color images, and new information using advanced techniques, including perfusion and diffusion MRI and functional MRI. A companion Website will offer the fully searchable text and an image bank.
Book Synopsis Quantitative Spinal Cord MRI in Radiologically Isolated Syndrome by :
Download or read book Quantitative Spinal Cord MRI in Radiologically Isolated Syndrome written by and published by . This book was released on 2018 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Structural, Quantitative and Functional MRI for the Study of Demyelinating Diseases of the Spinal Cord by : Romina Mariano
Download or read book Structural, Quantitative and Functional MRI for the Study of Demyelinating Diseases of the Spinal Cord written by Romina Mariano and published by . This book was released on 2020 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Magnetic Resonance Spectroscopy in Multiple Sclerosis by : M. Filippi
Download or read book Magnetic Resonance Spectroscopy in Multiple Sclerosis written by M. Filippi and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent years have witnessed dramatic advances in the development and use of magnetic resonance imaging (MRI) techniques that can provide quantitative measures with some degree of pathological specificity for the heterogeneous substrates of multiple sclerosis (MS). Magnetic resonance spectroscopy (MRS) is one of the most promising of these techniques. Thanks to MRS, axonal damage is no longer considered an end-stage phenomenon typical of only the most destructive lesions and the most unfortunate cases, but rather as a major component of the MS pathology of lesions and normal-appearing white matter at all the phases of the disease. This new concept is rapidly changing our understanding of MS pathophysiology and, as a consequence, the therapeutic strategies to modify the disease course favorably. Many of the authors have pionereed the use of MRS in MS, thus contributing to the foundation of the "axonal hypothesis".
Book Synopsis Diseases of the Brain, Head and Neck, Spine 2020–2023 by : Juerg Hodler
Download or read book Diseases of the Brain, Head and Neck, Spine 2020–2023 written by Juerg Hodler and published by Springer Nature. This book was released on 2020-02-14 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book offers an essential overview of brain, head and neck, and spine imaging. Over the last few years, there have been considerable advances in this area, driven by both clinical and technological developments. Written by leading international experts and teachers, the chapters are disease-oriented and cover all relevant imaging modalities, with a focus on magnetic resonance imaging and computed tomography. The book also includes a synopsis of pediatric imaging. IDKD books are rewritten (not merely updated) every four years, which means they offer a comprehensive review of the state-of-the-art in imaging. The book is clearly structured and features learning objectives, abstracts, subheadings, tables and take-home points, supported by design elements to help readers navigate the text. It will particularly appeal to general radiologists, radiology residents, and interventional radiologists who want to update their diagnostic expertise, as well as clinicians from other specialties who are interested in imaging for their patient care.
Book Synopsis Quantitative Magnetic Resonance Imaging of the Lumbar Spine by : Norbert Boos (Chirurg.)
Download or read book Quantitative Magnetic Resonance Imaging of the Lumbar Spine written by Norbert Boos (Chirurg.) and published by . This book was released on 1997 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis MR Imaging in White Matter Diseases of the Brain and Spinal Cord by : Massimo Filippi
Download or read book MR Imaging in White Matter Diseases of the Brain and Spinal Cord written by Massimo Filippi and published by Springer Science & Business Media. This book was released on 2005-12-29 with total page 463 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent decades, the use of neuroimaging techniques has resulted in outstanding progress in the diagnosis and management of neurological diseases, and this is particularly true of those diseases that affect the white matter of the brain and spinal cord. This book, written by internationally acclaimed experts, comprises a series of comprehensive and up-to-date reviews on the use of MR imaging in these major neurological conditions. The diverse available MR techniques, such as magnetization transfer MRI, diffusion-weighted MRI, MR spectroscopy, functional MRI, cell-specific MRI, perfusion MRI, and microscopic imaging with ultra-high field MRI, offer an extraordinarily powerful means of gaining fundamental in vivo insights into disease processes. The strengths and weaknesses of all these techniques in the study of multiple sclerosis and other relevant diseases are extensively considered. After an introductory section on neuroimaging technology, subsequent sections address disorders of myelination, demyelinating diseases, immune-mediated disorders, and white matter disorders related to aging and other conditions. This book provides a valuable summary of the state of the art in the field, and defines important areas for future research.
