Targeted Protein Degradation

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Author :
Publisher : Humana
ISBN 13 : 9781071616642
Total Pages : 351 pages
Book Rating : 4.6/5 (166 download)

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Book Synopsis Targeted Protein Degradation by : Angela M. Cacace

Download or read book Targeted Protein Degradation written by Angela M. Cacace and published by Humana. This book was released on 2021-08-26 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains a collection of innovative techniques for studying targeted protein degradation. Chapters guide readers through heterobifunctional proteolysis-targeting chimeras (PROTACs) approaches, E3 ligase, E3 ligase-induced ubiquitylation, proteomic approaches, novel degrader molecules, molecular glue, and stabilize binding interaction between a target and E3 ubiquitin ligase. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Targeted Protein Degradation: Methods and Protocols aims to ensure successful results in this emerging field of drug discovery.

Portable Chemical Sensors

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Publisher : Springer Science & Business Media
ISBN 13 : 9400728727
Total Pages : 350 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Portable Chemical Sensors by : Dimitrios P. Nikolelis

Download or read book Portable Chemical Sensors written by Dimitrios P. Nikolelis and published by Springer Science & Business Media. This book was released on 2012-02-02 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biosensors are making a large impact in environmental, food, biomedical, and other applications. In comparison to standard analytical detection methods, such as minimal sample preparation and handling, they offer advantages including real time detection, rapid detection of the analytes of concern, use of non-skilled personnel, and portability. The aim of this book is to focus on research related to the rapid detection of agents and weapons of bioterrorism and provide a comprehensive review of the research topics most pertinent to advancing devices applicable to the rapid real-time detection of toxicants such as microbes, pathogens, toxins, or nerve gases. The ongoing war on terrorism and the rising security concerns are driving the need for newer faster biosensors against bio-warfare agents for both military and civil defence applications. The volume brings together contributions from the most eminent international researchers in the field, covering various aspects of work not so far published in any scientific journal and often going beyond the “state of art “ . Readers of these review articles will learn new technological schemes that can lead to the construction of devices that will minimize the risk of bio-terrorism.

The Facts on File Dictionary of Biotechnology and Genetic Engineering

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Author :
Publisher : Checkmark Books
ISBN 13 : 9780816042746
Total Pages : 228 pages
Book Rating : 4.0/5 (427 download)

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Book Synopsis The Facts on File Dictionary of Biotechnology and Genetic Engineering by : Mark L. Steinberg

Download or read book The Facts on File Dictionary of Biotechnology and Genetic Engineering written by Mark L. Steinberg and published by Checkmark Books. This book was released on 2001 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: Defines more than 1900 terms, and serves the research needs of both the student and the advanced researcher.

Clinical Laboratory Chemistry

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Publisher : Pearson
ISBN 13 : 013441358X
Total Pages : 672 pages
Book Rating : 4.1/5 (344 download)

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Book Synopsis Clinical Laboratory Chemistry by : Robert Sunheimer

Download or read book Clinical Laboratory Chemistry written by Robert Sunheimer and published by Pearson. This book was released on 2017-04-24 with total page 672 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the eBook of the printed book and may not include any media, website access codes, or print supplements that may come packaged with the bound book. Specifically designed for use in Clinical Chemistry courses in clinical laboratory technician/medical laboratory technician (CLT/MLT) and clinical laboratory science/medical technology (CLS/MT) education programs. A reader-friendly introduction that focuses on the essential analytes CLT/MLT and CLS/MT students will use in the lab Clinical Laboratory Chemistry is a part of Pearson’s Clinical Laboratory Science series of textbooks, which is designed to balance theory and application in an engaging and useful way. Highly readable, the book concentrates on clinically significant analyses students are likely to encounter in the lab. The combination of detailed technical information and real-life case studies helps learners envision themselves as members of the health care team, providing the laboratory services specific to chemistry that assist in patient care. The book’s fundamental approach and special features allow students to analyze and synthesize information, and better understand the ever-evolving nature of clinical chemistry. The Second Edition has been streamlined and updated to include four new chapters covering safety, pediatrics, geriatrics, and nutrition; real-life mini cases; new figures and photographs; updated sources and citations; and a complete teaching and learning package.

Molecular Embryology

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1592592708
Total Pages : 752 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Molecular Embryology by : Paul T. Sharpe

Download or read book Molecular Embryology written by Paul T. Sharpe and published by Springer Science & Business Media. This book was released on 2008-02-02 with total page 752 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most people have some interest in embryos; this probably results, in part, from their interest in understanding the biological origins of themselves and their offspring and, increasingly, concerns about how environmental change such as pollution might affect human development. Obviously, et- cal considerations preclude experimental studies of human embryos and, c- sequently, the developmental biologist has turned to other species to examine this process. Fortunately, the most significant conclusion to be drawn from the experimental embryology of the last two decades is the manner in which orthologous or closely related molecules are deployed to mediate similar - velopmental processes in both vertebrates and invertebrates. The molecular mechanisms regulating processes fundamental to most animals, such as axial patterning or axon guidance, are frequently conserved during evolution. (It is now widely believed that the differences between phyla and classes are the result of new genes, arising mostly by duplication and divergence of extant sequences, regulating the appearance of derived characters. ) Other vertebrates are obviously most likely to use the same devel- mental mechanisms as humans and, within the vertebrate subphylum, the - parent degree of conservation of developmental mechanism is considerable. It has long been recognized that particular vertebrate species offer either d- tinct advantages in investigating particular stages of development or are - pecially amenable to particular manipulations. No single animal can provide all the answers because not all types of experiments can be carried out on a single species.

Flow Analysis with Spectrophotometric and Luminometric Detection

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Author :
Publisher : Elsevier
ISBN 13 : 0123859247
Total Pages : 483 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis Flow Analysis with Spectrophotometric and Luminometric Detection by : Elias A. G. Zagatto

Download or read book Flow Analysis with Spectrophotometric and Luminometric Detection written by Elias A. G. Zagatto and published by Elsevier. This book was released on 2012-01-05 with total page 483 pages. Available in PDF, EPUB and Kindle. Book excerpt: Machine generated contents note: 1. Introduction 2. Historical view 3. Fundamentals 4. Interaction of radiation with the flowing sample 5. Flow analysers 6. Instrumentation 7. Special strategies for flow manipulation 8. Sample handling.

Sample Introduction Systems in ICPMS and ICPOES

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Author :
Publisher : Newnes
ISBN 13 : 0444594833
Total Pages : 588 pages
Book Rating : 4.4/5 (445 download)

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Book Synopsis Sample Introduction Systems in ICPMS and ICPOES by : Diane Beauchemin

Download or read book Sample Introduction Systems in ICPMS and ICPOES written by Diane Beauchemin and published by Newnes. This book was released on 2020-03-15 with total page 588 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sample Introduction Systems in ICPMS and ICPOES provides an in-depth analysis of sample introduction strategies, including flow injection analysis and less common techniques, such as arc/spark ablation and direct sample insertion. The book critically evaluates what has been accomplished so far, along with what can be done to extend the capabilities of the technique for analyses of any type of sample, such as aqueous, gaseous or solid. The latest progress made in fields, such as FIA, ETV, LC-ICP-MS and CE-ICP-MS is included and critically discussed. The book addresses problems related to the optimization of the system, peak dispersion and calibration and automatization. - Provides contributions from recognized experts that give credibility to each chapter as a reference source - Presents a single source, providing the big picture for ICPMS and ICPOES - Covers theory, methods, selected applications and discrete sampling techniques - Includes access to core data for practical work, comparison of results and decision-making

Flow Analysis with Atomic Spectrometric Detectors

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Author :
Publisher : Elsevier
ISBN 13 : 0080531709
Total Pages : 489 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Flow Analysis with Atomic Spectrometric Detectors by : A. Sanz-Medel

Download or read book Flow Analysis with Atomic Spectrometric Detectors written by A. Sanz-Medel and published by Elsevier. This book was released on 1999-02-25 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: Flow Analysis (FA) offers a very convenient and fast approach to enhance and automate 'preliminary steps' of analysis (sample dissolution, pretreatments, preconcentrations, etc.) for atomic spectrometric detectors (ASD). Moreover, flow manifolds can ease the well-known problem of sample introduction/presentation to atomisers or even expand the classical scope of atomic/elemental information, characterizing atomic spectrometry, into the realm of molecules and metal-compounds analysis (e.g. by resorting to coupled separation techniques). All these facts could explain both the extraordinary interest for research and the great importance for practical problem-solving achieved nowadays by FA-ASD.On the threshold of the new millennium when plasma emission and mass spectrometry are so important and popular, the editor considered it timely to produce a book which covers all present atomic detectors and techniques where FA has been or can be advantageously employed. The book has been conceived in three separate parts:Part I gives the fundamental, instrumentation and potential of FIA as a most versatile sample presentation/introduction system for atomic spectrometry.Part II provides a modern account of fundamentals, possibilities and applications offered by flow analysis to atomic spectrometry for on-line sample pretreatments, separations and preconcentrations.Part III deals with applications of FA-ASD combinations to analytical problem-solving in most varied fields and situations.This monograph integrates the most popular aspects of FIA, its new developments for sample on-line treatments and on-line non-chromatographic and chromatographic separations (all typical 'flow analysis') in connection with all branches of analytical atomic spectrometry. Thus, academics, researchers and routine users of analytical atomic spectrometry will find this book invaluable.

Hydrocarbons and Air Pollution

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Author :
Publisher :
ISBN 13 :
Total Pages : 1212 pages
Book Rating : 4.3/5 ( download)

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Book Synopsis Hydrocarbons and Air Pollution by : Air Pollution Technical Information Center

Download or read book Hydrocarbons and Air Pollution written by Air Pollution Technical Information Center and published by . This book was released on 1970 with total page 1212 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Fundamentals and Analytical Applications of Multiway Calibration

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Author :
Publisher : Elsevier
ISBN 13 : 0444635378
Total Pages : 612 pages
Book Rating : 4.4/5 (446 download)

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Book Synopsis Fundamentals and Analytical Applications of Multiway Calibration by :

Download or read book Fundamentals and Analytical Applications of Multiway Calibration written by and published by Elsevier. This book was released on 2015-08-10 with total page 612 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fundamentals and Analytical Applications of Multi-Way Calibration presents researchers with a set of effective tools they can use to obtain the maximum information from instrumental data. It includes the most advanced techniques, methods, and algorithms related to multi-way calibration and the ways they can be applied to solve actual analytical problems. This book provides a comprehensive coverage of the main aspects of multi-way analysis, including fundamentals and selected applications of chemometrics that can resolve complex analytical chemistry problems through the use of multi-way calibration. Includes the most advanced techniques, methods, and algorithms related to multi-way calibration and the ways they can be applied to solve actual analytical problems Presents researchers with a set of effective tools they can use to obtain the maximum information from instrumental data Provides comprehensive coverage of the main aspects of multi-way analysis, including fundamentals and selected applications of chemometrics

Flow-injection Analysis

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Author :
Publisher :
ISBN 13 :
Total Pages : 426 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Flow-injection Analysis by : Miguel Valcárcel Cases

Download or read book Flow-injection Analysis written by Miguel Valcárcel Cases and published by . This book was released on 1987 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Handbook of Industrial and Hazardous Wastes Treatment

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Author :
Publisher : CRC Press
ISBN 13 : 9780203026519
Total Pages : 1368 pages
Book Rating : 4.0/5 (265 download)

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Book Synopsis Handbook of Industrial and Hazardous Wastes Treatment by : Lawrence K. Wang

Download or read book Handbook of Industrial and Hazardous Wastes Treatment written by Lawrence K. Wang and published by CRC Press. This book was released on 2004-06-29 with total page 1368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presenting effective, practicable strategies modeled from ultramodern technologies and framed by the critical insights of 78 field experts, this vastly expanded Second Edition offers 32 chapters of industry- and waste-specific analyses and treatment methods for industrial and hazardous waste materials-from explosive wastes to landfill leachate to w

Frontiers in Biosensorics I

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 9783764354756
Total Pages : 302 pages
Book Rating : 4.3/5 (547 download)

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Book Synopsis Frontiers in Biosensorics I by : F.W. Scheller

Download or read book Frontiers in Biosensorics I written by F.W. Scheller and published by Springer Science & Business Media. This book was released on 1996-12-01 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume I provides an in-depth discussion of the most recent developments of crucical biosensor components. It concentrates on the interface between the analyte phase and the detector, namely, the implementation of novel recognition elements, including nucleic acids, and of leading-edge technology in the construction of responsive thin layers. Thus, the reader can obtain a foretaste of achievable future progress in the field.

Biogenic Nano-Particles and their Use in Agro-ecosystems

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Author :
Publisher : Springer Nature
ISBN 13 : 981152985X
Total Pages : 610 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Biogenic Nano-Particles and their Use in Agro-ecosystems by : Mansour Ghorbanpour

Download or read book Biogenic Nano-Particles and their Use in Agro-ecosystems written by Mansour Ghorbanpour and published by Springer Nature. This book was released on 2020-03-20 with total page 610 pages. Available in PDF, EPUB and Kindle. Book excerpt: Several nano-scale devices have emerged that are capable of analysing plant diseases, nutrient deficiencies and any other ailments that may affect food security in agro-ecosystems. It has been envisioned that smart delivery systems can be developed and utilised for better management of agricultural ecosystems. These systems could exhibit beneficial, multi-functional characteristics, which could be used to assess and also control habitat-imposed stresses to crops. Nanoparticle-mediated smart delivery systems can control the delivery of nutrients or bioactive and/or pesticide molecules in plants. It has been suggested that nano-particles in plants might help determine their nutrient status and could also be used as cures in agro-ecosystems. Further, to enhance soil and crop productivity, nanotechnology has been used to create and deliver nano fertilizers, which can be defined as nano-particles that directly help supply nutrients for plant growth and soil productivity. Nano-particles can be absorbed onto clay networks, leading to improved soil health and more efficient nutrient use by crops. Additionally, fertilizer particles can be coated with nano-particles that facilitate slow and steady release of nutrients, reducing loss of nutrients and enhancing their efficiency in agri-crops. Although the use of nanotechnology in agro-ecosystems is still in its early stages and needs to be developed further, nano-particle-mediated delivery systems are promising solutions for the successful management of agri-ecosystems. In this context, the book offers insights into nanotechnology in agro-ecosystems with reference to biogenic nanoparticles. It highlights the: • occurrence and diversity of Biogenic Nanoparticles • mechanistic approach involved in the synthesis of biogenic nanoparticles • synthesis of nanoparticles using photo-activation, and their fate in the soil ecosystem • potential applications of nanoparticles in agricultural systems • application and biogenic synthesis of gold nanoparticles and their characterization • impact of biogenic nanoparticles on biotic stress to plants • mechanistic approaches involved in the antimicrobial effects and cytotoxicity of biogenic nanoparticles • role of biogenic nanoparticles in plant diseases management • relevance of biological synthesized nanoparticles in the longevity of agricultural crops • design and synthesis of nano-biosensors for monitoring pollutants in water, soil and plant systems • applications of nanotechnology in agriculture with special refer to soil, water and plant sciences A useful resource for postgraduate and research students in the field of plant and agricultural sciences, it is also of interest to researchers working in nano and biotechnology.

Whole Genome Amplification

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Author :
Publisher : Methods Express (Paperback)
ISBN 13 :
Total Pages : 224 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Whole Genome Amplification by : Simon Hughes

Download or read book Whole Genome Amplification written by Simon Hughes and published by Methods Express (Paperback). This book was released on 2005 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: Whole genome amplification generates microgram quantities of genomic DNA starting from a sample of as little as a few femtograms and so is a vital technique when sample material is limited, as well as for high-throughput assays. Whole Genome Amplification: Methods Expressis a comprehensive up-to-date laboratory manual for this key technique. It provides detailed step-by-step protocols as well as hints and tips for success and troubleshooting, taking readers through all aspects of whole genome amplification. This book is an essential practical guide for any researcher currently using PCR for genomic amplification or who wishes to do so in future.

Industrial Waste Treatment

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Author :
Publisher : Elsevier
ISBN 13 : 0080471080
Total Pages : 586 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Industrial Waste Treatment by : Nelson Leonard Nemerow

Download or read book Industrial Waste Treatment written by Nelson Leonard Nemerow and published by Elsevier. This book was released on 2010-07-27 with total page 586 pages. Available in PDF, EPUB and Kindle. Book excerpt: Taking the reader through the history of industrial waste treatment and directing them toward a new path of best practice, Industrial Waste Treatment illustrates how current treatment techniques are affected by regulatory and economic constraints, scientific knowledge and tolerances. This book provides the reader with the basis for a more effective method of waste treatment which is sustainable and supportive of industrial improvements. Overall, it provides valuable information for planners, industrial, civil and environmental engineers and government officials for a better understanding of current practices and regulatory history and how these factors relate to the ability to complete environmental solutions to industrial waste problems. - Provides environmental history from a professional/technical point-of-view as a basis for total solutions engineering - Includes sustainable practice necessary for the 21st Century - Thoroughly explores industry and environmental regulations over the past 150 years

Radical Encounters

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Author :
Publisher : Bold Strokes Books Inc
ISBN 13 : 1602822492
Total Pages : 258 pages
Book Rating : 4.6/5 (28 download)

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Book Synopsis Radical Encounters by : Radclyffe

Download or read book Radical Encounters written by Radclyffe and published by Bold Strokes Books Inc. This book was released on 2009-02-17 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: Award-winning erotica and romance writer Radclyffe explores the outer reaches of desire and the shifting gender terrain beyond butch-femme: an initiate tests her limits in a men’s leather bar, a construction worker gets a special treat during her noon break, a porn star tells…and shows…all, a femme instructs her straight girlfriends in the fine art of fellatio, and twenty more radically erotic encounters.