Quality Assurance In The Era Of Individualized Medicine

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Quality Assurance in the Era of Individualized Medicine

Author : Moumtzoglou, Anastasius S.
Publisher : IGI Global
ISBN 13 : 1799823911
Total Pages : 346 pages
Book Rating : 4.7/5 (998 download)

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Book Synopsis Quality Assurance in the Era of Individualized Medicine by : Moumtzoglou, Anastasius S.

Download or read book Quality Assurance in the Era of Individualized Medicine written by Moumtzoglou, Anastasius S. and published by IGI Global. This book was released on 2019-11-29 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is a significant deficiency among contemporary medicine practices reflected by experts making medical decisions for a large proportion of the population for which no or minimal data exists. Fortunately, our capacity to procure and apply such information is rapidly rising. As medicine becomes more individualized, the implementation of health IT and data interoperability become essential components to delivering quality healthcare. Quality Assurance in the Era of Individualized Medicine is a collection of innovative research on the methods and utilization of digital readouts to fashion an individualized therapy instead of a mass-population-directed strategy. While highlighting topics including assistive technologies, patient management, and clinical practices, this book is ideally designed for health professionals, doctors, nurses, hospital management, medical administrators, IT specialists, data scientists, researchers, academicians, and students.

Registries for Evaluating Patient Outcomes

Author : Agency for Healthcare Research and Quality/AHRQ
Publisher : Government Printing Office
ISBN 13 : 1587634333
Total Pages : 385 pages
Book Rating : 4.5/5 (876 download)

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Book Synopsis Registries for Evaluating Patient Outcomes by : Agency for Healthcare Research and Quality/AHRQ

Download or read book Registries for Evaluating Patient Outcomes written by Agency for Healthcare Research and Quality/AHRQ and published by Government Printing Office. This book was released on 2014-04-01 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: This User’s Guide is intended to support the design, implementation, analysis, interpretation, and quality evaluation of registries created to increase understanding of patient outcomes. For the purposes of this guide, a patient registry is an organized system that uses observational study methods to collect uniform data (clinical and other) to evaluate specified outcomes for a population defined by a particular disease, condition, or exposure, and that serves one or more predetermined scientific, clinical, or policy purposes. A registry database is a file (or files) derived from the registry. Although registries can serve many purposes, this guide focuses on registries created for one or more of the following purposes: to describe the natural history of disease, to determine clinical effectiveness or cost-effectiveness of health care products and services, to measure or monitor safety and harm, and/or to measure quality of care. Registries are classified according to how their populations are defined. For example, product registries include patients who have been exposed to biopharmaceutical products or medical devices. Health services registries consist of patients who have had a common procedure, clinical encounter, or hospitalization. Disease or condition registries are defined by patients having the same diagnosis, such as cystic fibrosis or heart failure. The User’s Guide was created by researchers affiliated with AHRQ’s Effective Health Care Program, particularly those who participated in AHRQ’s DEcIDE (Developing Evidence to Inform Decisions About Effectiveness) program. Chapters were subject to multiple internal and external independent reviews.

Improving Healthcare Quality in Europe Characteristics, Effectiveness and Implementation of Different Strategies

Author : OECD
Publisher : OECD Publishing
ISBN 13 : 9264805907
Total Pages : 447 pages
Book Rating : 4.2/5 (648 download)

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Book Synopsis Improving Healthcare Quality in Europe Characteristics, Effectiveness and Implementation of Different Strategies by : OECD

Download or read book Improving Healthcare Quality in Europe Characteristics, Effectiveness and Implementation of Different Strategies written by OECD and published by OECD Publishing. This book was released on 2019-10-17 with total page 447 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume, developed by the Observatory together with OECD, provides an overall conceptual framework for understanding and applying strategies aimed at improving quality of care. Crucially, it summarizes available evidence on different quality strategies and provides recommendations for their implementation. This book is intended to help policy-makers to understand concepts of quality and to support them to evaluate single strategies and combinations of strategies.

Precision Medicine and Artificial Intelligence

Author : Michael Mahler
Publisher : Academic Press
ISBN 13 : 032385432X
Total Pages : 302 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis Precision Medicine and Artificial Intelligence by : Michael Mahler

Download or read book Precision Medicine and Artificial Intelligence written by Michael Mahler and published by Academic Press. This book was released on 2021-03-12 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: Precision Medicine and Artificial Intelligence: The Perfect Fit for Autoimmunity covers background on artificial intelligence (AI), its link to precision medicine (PM), and examples of AI in healthcare, especially autoimmunity. The book highlights future perspectives and potential directions as AI has gained significant attention during the past decade. Autoimmune diseases are complex and heterogeneous conditions, but exciting new developments and implementation tactics surrounding automated systems have enabled the generation of large datasets, making autoimmunity an ideal target for AI and precision medicine. More and more diagnostic products utilize AI, which is also starting to be supported by regulatory agencies such as the Food and Drug Administration (FDA). Knowledge generation by leveraging large datasets including demographic, environmental, clinical and biomarker data has the potential to not only impact the diagnosis of patients, but also disease prediction, prognosis and treatment options. - Allows the readers to gain an overview on precision medicine for autoimmune diseases leveraging AI solutions - Provides background, milestone and examples of precision medicine - Outlines the paradigm shift towards precision medicine driven by value-based systems - Discusses future applications of precision medicine research using AI - Other aspects covered in the book include regulatory insights, data analytics and visualization, types of biomarkers as well as the role of the patient in precision medicine

Quality Control of Cellular Protein in Neurodegenerative Disorders

Author : Uddin, Md. Sahab
Publisher : IGI Global
ISBN 13 : 1799813185
Total Pages : 515 pages
Book Rating : 4.7/5 (998 download)

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Book Synopsis Quality Control of Cellular Protein in Neurodegenerative Disorders by : Uddin, Md. Sahab

Download or read book Quality Control of Cellular Protein in Neurodegenerative Disorders written by Uddin, Md. Sahab and published by IGI Global. This book was released on 2020-02-14 with total page 515 pages. Available in PDF, EPUB and Kindle. Book excerpt: Protein misfolding and aggregation are hallmarks of several neurodegenerative proteinopathies. Though multiple factors like aging, oxidative stress, mitochondrial dysfunction, proteotoxic insults, genetic inconsistency, etc. are responsible for the dysfunction of the neuronal protein quality control system, targeting protein quality control has become an auspicious approach to halt the propagation of neurodegeneration. Quality Control of Cellular Protein in Neurodegenerative Disorders provides diverse aspects exploring the role of the protein quality control in neurodegenerative disorders and potential therapeutic strategies to combat the development and propagation of neurodegeneration. Featuring coverage on a broad range of topics such as molecular chaperones, protein misfolding, and stress signaling, this book is ideally designed for neurobiologists, neuropsychologists, neurophysiologists, medical professionals, neuropathologists, researchers, academicians, students, and practitioners engaged in studies of the protein quality control system in neuronal cells.

Convergence of Population Health Management, Pharmacogenomics, and Patient-Centered Care

Author : Moumtzoglou, Anastasius S.
Publisher : IGI Global
ISBN 13 :
Total Pages : 578 pages
Book Rating : 4.3/5 (693 download)

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Book Synopsis Convergence of Population Health Management, Pharmacogenomics, and Patient-Centered Care by : Moumtzoglou, Anastasius S.

Download or read book Convergence of Population Health Management, Pharmacogenomics, and Patient-Centered Care written by Moumtzoglou, Anastasius S. and published by IGI Global. This book was released on 2024-09-27 with total page 578 pages. Available in PDF, EPUB and Kindle. Book excerpt: The current healthcare framework, often characterized by standardized treatments and one-size-fits-all approaches, falls short in addressing the unique genetic compositions, lifestyles, and environmental factors that influence individual patient outcomes. This gap necessitates a radical reevaluation of healthcare practices, from reshaping infrastructure to redefining the roles of patients and doctors. The challenges are formidable, requiring critical reflection and bold initiatives to overcome obstacles and pave the way for a future where patient-centered care seamlessly integrates with population health management, leveraging data, technology, ethics, and collaboration for a global healthcare revolution. Convergence of Population Health Management, Pharmacogenomics, and Patient-Centered Care is a book that unveils a comprehensive exploration of solutions and pathways towards this transformative vision. This comprehensive guide is tailored for academic scholars, healthcare professionals, and students navigating the landscape of personalized medicine, population health management, and the digitalization of healthcare. Authored by leading experts, the book aims to serve as a compendium of terms, definitions, and in-depth explanations of key concepts. Its objectives include supporting students in understanding healthcare domains, aiding healthcare professionals in meeting patient needs, assisting patients in deriving more benefits from their healthcare, and guiding e-health systems' designers and managers in grounding practices on the science of individuality.

Crossing the Quality Chasm

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309132967
Total Pages : 359 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Crossing the Quality Chasm by : Institute of Medicine

Download or read book Crossing the Quality Chasm written by Institute of Medicine and published by National Academies Press. This book was released on 2001-07-19 with total page 359 pages. Available in PDF, EPUB and Kindle. Book excerpt: Second in a series of publications from the Institute of Medicine's Quality of Health Care in America project Today's health care providers have more research findings and more technology available to them than ever before. Yet recent reports have raised serious doubts about the quality of health care in America. Crossing the Quality Chasm makes an urgent call for fundamental change to close the quality gap. This book recommends a sweeping redesign of the American health care system and provides overarching principles for specific direction for policymakers, health care leaders, clinicians, regulators, purchasers, and others. In this comprehensive volume the committee offers: A set of performance expectations for the 21st century health care system. A set of 10 new rules to guide patient-clinician relationships. A suggested organizing framework to better align the incentives inherent in payment and accountability with improvements in quality. Key steps to promote evidence-based practice and strengthen clinical information systems. Analyzing health care organizations as complex systems, Crossing the Quality Chasm also documents the causes of the quality gap, identifies current practices that impede quality care, and explores how systems approaches can be used to implement change.

Progress and Challenges in Precision Medicine

Author : Mukesh Verma
Publisher : Academic Press
ISBN 13 : 0128095024
Total Pages : 346 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Progress and Challenges in Precision Medicine by : Mukesh Verma

Download or read book Progress and Challenges in Precision Medicine written by Mukesh Verma and published by Academic Press. This book was released on 2016-12-22 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: Progress and Challenges in Precision Medicine presents an insightful overview to the myriad factors of personalized and precision medicine. The availability of the human genome, large amounts of data on individual genetic variations, environmental interactions, influence of lifestyle, and cutting-edge tools and technologies for big-data analysis have led to the age of personalized and precision medicine. Bringing together a global range of experts on precision medicine, this book collects previously scattered information into one concise volume which covers the most important developments so far in precision medicine and also suggests the most likely avenues for future development. The book includes clinical information, informatics, public policy implications, and information on case studies. It is a useful reference and background work for students, researchers, and clinicians working in the biomedical and medical fields, as well as policymakers in the health sciences. - Provides an overview of the growing field of precision medicine - Contains chapters from geographically diverse experts in their field - Explores important aspects of precision medicine, including applications, ethics, and development

Digital Identity in the New Era of Personalized Medicine

Author : Vasiliu-Feltes, Ingrid
Publisher : IGI Global
ISBN 13 : 179988967X
Total Pages : 290 pages
Book Rating : 4.7/5 (998 download)

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Book Synopsis Digital Identity in the New Era of Personalized Medicine by : Vasiliu-Feltes, Ingrid

Download or read book Digital Identity in the New Era of Personalized Medicine written by Vasiliu-Feltes, Ingrid and published by IGI Global. This book was released on 2022-11-18 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: Within the past decade, we have witnessed an increased adoption of emerging technologies as well as the exponential pace of scientific discoveries within all industries. The level of digital innovation and digital transformation experienced in healthcare and life sciences has been markedly accelerated by the COVID-19 pandemic. There is a new sense of urgency to design and develop a new global health ecosystem that is more suitable for the digital era and future generations. Deploying precision medicine solutions that can redefine the way we diagnose and treat disease, as well as shift the focus towards a customized human-centered approach, such as those offered by personalized medicine, can be a viable sustainable model. Digital Identity in the New Era of Personalized Medicine highlights the latest trends in precision medicine and the important role digital identity plays in upholding ethical values, safeguarding human rights, and practicing responsible personalized medicine. It provides an overview of the current healthcare legal and regulatory landscapes as well as some of the major challenges and opportunities we face in this digital, virtual, and precision medicine-powered era. Covering topics such as data-centric compliance, global health, and identity management, this book is an essential resource for doctors, healthcare administration, academicians, clinicians, health and bio-tech executives, researchers, medical professionals, medical engineers, medical students, and government officials looking for a resource that addresses challenges in healthcare including trust, privacy, data integrity, and ownership.

Quality of Healthcare in the Aftermath of the COVID-19 Pandemic

Author : Moumtzoglou, Anastasius
Publisher : IGI Global
ISBN 13 : 1799891992
Total Pages : 403 pages
Book Rating : 4.7/5 (998 download)

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Book Synopsis Quality of Healthcare in the Aftermath of the COVID-19 Pandemic by : Moumtzoglou, Anastasius

Download or read book Quality of Healthcare in the Aftermath of the COVID-19 Pandemic written by Moumtzoglou, Anastasius and published by IGI Global. This book was released on 2021-12-10 with total page 403 pages. Available in PDF, EPUB and Kindle. Book excerpt: The COVID-19 pandemic has put massive stress on healthcare professionals’ formal training, their creed to do no harm, and the patient safety movement. COVID-19 affects all aspects of daily life and healthcare’s organizational culture and values. Healthcare institutions experience absenteeism, change in commerce patterns, and interrupted supply/delivery in this context. It has also revealed the extensive amounts of data needed for population health management, as well as the opportunities afforded by mainstreaming telehealth and virtual care capabilities, thus making the implementation of health IT essential in the post-pandemic era. Quality of Healthcare in the Aftermath of the COVID-19 Pandemic clarifies how healthcare professionals might provide their services differently than treating a patient through its vicinity with multiple providers. It examines the notion that healthcare education requires a pack of healthcare workers from varied educational backgrounds and training levels for the nuances of a disease. Covering topics such as blockchain technology, power density analysis, and supply chain, this book is a valuable resource for undergraduate and extended degree program students, graduate students of healthcare quality and health services management, healthcare managers, health professionals, researchers, professors, and academicians.

Ethical Counselling and Medical Decision-Making in the Era of Personalised Medicine

Author : Giovanni Boniolo
Publisher : Springer
ISBN 13 : 3319276905
Total Pages : 129 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis Ethical Counselling and Medical Decision-Making in the Era of Personalised Medicine by : Giovanni Boniolo

Download or read book Ethical Counselling and Medical Decision-Making in the Era of Personalised Medicine written by Giovanni Boniolo and published by Springer. This book was released on 2016-02-20 with total page 129 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers an overview of the main questions arising when biomedical decision-making intersects ethical decision-making. It reports on two ethical decision-making methodologies, one addressing the patients, the other physicians. It shows how patients’ autonomous choices can be empowered by increasing awareness of ethical deliberation, and at the same time it supports healthcare professionals in developing an ethical sensitivity, which they can apply in their daily practice. The book highlights the importance and relevance of practicing bioethics in the age of personalized medicine. It presents concrete cases studies dealing with cancer and genetic diseases, where difficult decisions need to be made by all the parties involved: patients, physicians and families. Decisions concern not only diagnostic procedures and treatments, but also moral values, religious beliefs and ways of seeing life and death, thus adding further layers of complexity to biomedical decision-making. This book, which is strongly rooted in the philosophical tradition, features non-directive counseling and patient-centeredness. It provides a concise yet comprehensive and practice-oriented guide to decision-making in modern healthcare.

Ethnomedicinal Plant Use and Practice in Traditional Medicine

Author : Akash,
Publisher : IGI Global
ISBN 13 : 1799813215
Total Pages : 380 pages
Book Rating : 4.7/5 (998 download)

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Book Synopsis Ethnomedicinal Plant Use and Practice in Traditional Medicine by : Akash,

Download or read book Ethnomedicinal Plant Use and Practice in Traditional Medicine written by Akash, and published by IGI Global. This book was released on 2020-03-13 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traditional medicinal knowledge, especially the use of ethnomedicinal plants in developing countries, has been passed down for generations. Today, however, scientists are poised to combine traditional medicinal plants and modern drug discoveries to further develop essential products that have followed the leads of indigenous cures used for centuries. Ethnomedicinal Plant Use and Practice in Traditional Medicine provides emerging research exploring the theoretical and practical aspects of indigenous knowledge and therapeutic potential within ethnobotany. Featuring coverage on a broad range of topics such as drug discovery, traditional knowledge, and herbal medicine, this book is ideally designed for doctors, healers, medical professionals, ethnobotanists, naturalists, academicians, researchers, and students interested in current research on the medical use and applications of natural-based resources.

Handbook of Research on Prenatal, Postnatal, and Early Childhood Development

Author : Aral, Neriman
Publisher : IGI Global
ISBN 13 : 1799829545
Total Pages : 470 pages
Book Rating : 4.7/5 (998 download)

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Book Synopsis Handbook of Research on Prenatal, Postnatal, and Early Childhood Development by : Aral, Neriman

Download or read book Handbook of Research on Prenatal, Postnatal, and Early Childhood Development written by Aral, Neriman and published by IGI Global. This book was released on 2020-03-20 with total page 470 pages. Available in PDF, EPUB and Kindle. Book excerpt: Child development comprises children’s cognitive, linguistic, motor, social and emotional development, communication, and self-care skills. Understanding developmental periods means that possible problems or roadblocks can be planned for or prevented. Knowledge of child development is necessary for achieving educational goals and is integral to promoting children’s healthy and timely development. The Handbook of Research on Prenatal, Postnatal, and Early Childhood Development is an essential scholarly reference source that compiles critical findings on children’s growth periods and characteristics as well as the principles that affect their development. Covering a wide range of topics such as at-risk children, early intervention, and support programs, this book is ideally designed for child development specialists, pediatricians, educators, program developers, administrators, psychologists, researchers, academicians, and students. Additionally, the book provides insight and support to health professionals working in various disciplines in the field of child development and health.

Prediction in Medicine: The Impact of Machine Learning on Healthcare

Author : Neeta Verma
Publisher : Bentham Science Publishers
ISBN 13 : 9815305131
Total Pages : 339 pages
Book Rating : 4.8/5 (153 download)

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Book Synopsis Prediction in Medicine: The Impact of Machine Learning on Healthcare by : Neeta Verma

Download or read book Prediction in Medicine: The Impact of Machine Learning on Healthcare written by Neeta Verma and published by Bentham Science Publishers. This book was released on 2024-10-11 with total page 339 pages. Available in PDF, EPUB and Kindle. Book excerpt: Prediction in Medicine: The Impact of Machine Learning on Healthcare explores the transformative power of advanced data analytics and machine learning in healthcare. This comprehensive guide covers predictive analysis, leveraging electronic health records (EHRs) and wearable devices to optimize patient care and healthcare planning. Key topics include disease diagnosis, risk assessment, and precision medicine advancements in cardiovascular health and hypertension management. The book also addresses challenges in interpreting clinical data and navigating ethical considerations. It examines the role of AI in healthcare emergencies and infectious disease management, highlighting the integration of diverse data sources like medical imaging and genomic data. Prediction in Medicine is essential for students, researchers, healthcare professionals, and general readers interested in the future of healthcare and technological innovation.

Quality Assurance in Healthcare Service Delivery, Nursing and Personalized Medicine: Technologies and Processes

Author : Lazakidou, Athina
Publisher : IGI Global
ISBN 13 : 1613501218
Total Pages : 301 pages
Book Rating : 4.6/5 (135 download)

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Book Synopsis Quality Assurance in Healthcare Service Delivery, Nursing and Personalized Medicine: Technologies and Processes by : Lazakidou, Athina

Download or read book Quality Assurance in Healthcare Service Delivery, Nursing and Personalized Medicine: Technologies and Processes written by Lazakidou, Athina and published by IGI Global. This book was released on 2011-09-30 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: Quality of life is difficult to define and even more difficult to measure; as such, outcomes from nursing in continuing care are not easily articulated. Quality Assurance in Healthcare Service Delivery, Nursing and Personalized Medicine: Technologies and Processes offers a framework for measuring quality of service in the healthcare industry as it pertains to nursing, with insight into how new technologies and the design of personalized medicine have improved quality of care and quality of life. Assessment and feedback are a vital part of developing and designing personalized medicine, and this book details case studies and the latest research in the field of healthcare service delivery assessment. In addition to describing assessment methodology, the book is also a compendium of the latest research into new medical technologies.

Transitioning Healthcare Support in Developing Countries From the US to China: Emerging Research and Opportunities

Author : Eyombo, Leo
Publisher : IGI Global
ISBN 13 : 179984451X
Total Pages : 135 pages
Book Rating : 4.7/5 (998 download)

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Book Synopsis Transitioning Healthcare Support in Developing Countries From the US to China: Emerging Research and Opportunities by : Eyombo, Leo

Download or read book Transitioning Healthcare Support in Developing Countries From the US to China: Emerging Research and Opportunities written by Eyombo, Leo and published by IGI Global. This book was released on 2021-05-21 with total page 135 pages. Available in PDF, EPUB and Kindle. Book excerpt: In terms of healthcare, in both the People’s Republic of China and the United States there have been dramatic changes within the past 60 years. The PRC has evolved to be a superpower and a major player in the international healthcare development arena whereas the USA has struggled to maintain its image as a major builder of soft diplomacy. When it comes to delivering healthcare, Africa is a continent with many developing countries with individualized needs that calls for individualized healthcare plans, and both the PRC and USA have struggled with this relationship. The PRC on one hand has had social conflict with the average African, which has been detrimental to relations, the USA on the other hand, has reduced international development funds and has been in a healthcare crisis of its own. Due to these changes, Africa has essentially become the last battleground for soft power with healthcare being the measuring tool. Transitioning Healthcare Support in Developing Countries From the US to China: Emerging Research and Opportunities explores the history of healthcare in Africa from the 1960s to the COVID-19 (Coronavirus) Pandemic in 2020. This book examines the relationship between the People’s Republic of China (PRC) and the United States of America (USA) in providing healthcare services to Africa and documents the struggles and areas of both success and failure in doing so. The chapters cover issues such as racism in PRC residing in Africa and the USA’s struggle with coronavirus. This book is ideal for government officials, medical personnel, policymakers, international agencies, practitioners, stakeholders, researchers, academicians, and students interested in the relations and healthcare delivery between both the USA and PRC to Africa.

Finding What Works in Health Care

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309164257
Total Pages : 267 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Finding What Works in Health Care by : Institute of Medicine

Download or read book Finding What Works in Health Care written by Institute of Medicine and published by National Academies Press. This book was released on 2011-07-20 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: Healthcare decision makers in search of reliable information that compares health interventions increasingly turn to systematic reviews for the best summary of the evidence. Systematic reviews identify, select, assess, and synthesize the findings of similar but separate studies, and can help clarify what is known and not known about the potential benefits and harms of drugs, devices, and other healthcare services. Systematic reviews can be helpful for clinicians who want to integrate research findings into their daily practices, for patients to make well-informed choices about their own care, for professional medical societies and other organizations that develop clinical practice guidelines. Too often systematic reviews are of uncertain or poor quality. There are no universally accepted standards for developing systematic reviews leading to variability in how conflicts of interest and biases are handled, how evidence is appraised, and the overall scientific rigor of the process. In Finding What Works in Health Care the Institute of Medicine (IOM) recommends 21 standards for developing high-quality systematic reviews of comparative effectiveness research. The standards address the entire systematic review process from the initial steps of formulating the topic and building the review team to producing a detailed final report that synthesizes what the evidence shows and where knowledge gaps remain. Finding What Works in Health Care also proposes a framework for improving the quality of the science underpinning systematic reviews. This book will serve as a vital resource for both sponsors and producers of systematic reviews of comparative effectiveness research.