Qualite De Levaluation De La Toxicite De Limmunotherapie Dans Les Essais De Phase 3 En Oncologie

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Peritoneal Carcinomatosis from Ovarian Cancer

Author : Konstantinos N. Chatzigeorgiou
Publisher : Nova Science Publishers
ISBN 13 :
Total Pages : 234 pages
Book Rating : 4.:/5 ( download)

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Book Synopsis Peritoneal Carcinomatosis from Ovarian Cancer by : Konstantinos N. Chatzigeorgiou

Download or read book Peritoneal Carcinomatosis from Ovarian Cancer written by Konstantinos N. Chatzigeorgiou and published by Nova Science Publishers. This book was released on 2005 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ovarian cancer is the most common cause of death among all gynecological neoplasms. Ovarian epithelial cancer represents approximately 90% of all ovarian malignant tumours. The most usual pattern of spread and probably the earliest kind of metastasis of ovarian cancer is intraperitoneal spread, caused by apoptosis of viable cancer cells, even in cases where the ovarian surface has no visible rupture. Approximately 70% to 75% of all ovarian cancers are being diagnosed with peritoneal carcinomatosis and ascites in advanced stages III and IV. Peritoneal carcinomatosis from ovarian cancer may occur either concomitantly with the primary tumour or as a recurrence pattern of spread. Standard treatment consists of surgical debulking and postoperative systemic chemotherapy. Response rates to first-line chemotherapy with platinum/taxane combinations are high, about 70-80%, but the vast majority of patients will relapse. Peritoneal seeding is a major cause of surgical treatment failure among those patients, even after optimal debulking. However, progressing ovarian cancer tends to remain within the peritoneal cavity or, better-expressed, ovarian cancer is a cancer of the peritoneum. The administration of cytotoxic agents directly into the peritoneal cavity as treatment for malignancy was initially evaluated more than 40 years ago. Over the past two decades regional therapy of ovarian cancer has evolved from just an interesting pharmacokinetic concept into a viable management option for women with advanced disease. Several authors, and among them some of the world's leading experts on this field present the current knowledge and their experience on peritoneal carcinomatosis from ovarian cancer.

Handbook of Psychiatry in Palliative Medicine

Author : Harvey Max Chochinov
Publisher :
ISBN 13 : 0195301072
Total Pages : 591 pages
Book Rating : 4.1/5 (953 download)

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Book Synopsis Handbook of Psychiatry in Palliative Medicine by : Harvey Max Chochinov

Download or read book Handbook of Psychiatry in Palliative Medicine written by Harvey Max Chochinov and published by . This book was released on 2009 with total page 591 pages. Available in PDF, EPUB and Kindle. Book excerpt: Psychiatric, or psychosocial, palliative care has transformed palliative medicine. Palliation that neglects psychosocial dimensions of patient and family experience fails to meet contemporary standards of comprehensive palliative care. While a focus on somatic issues has sometimes overshadowed attention to psychological, existential, and spiritual end-of-life challenges, the past decade has seen an all encompassing, multi-disciplinary approach to care for the dying take hold. Written by internationally known psychiatry and palliative care experts, the Handbook of Psychiatry in Palliative Medicine is an essential reference for all providers of palliative care, including psychiatrists, psychologists, mental health counselors, oncologists, hospice workers, and social workers.

Critical Care Nursing

Author : Linda Diann Urden
Publisher : Saunders
ISBN 13 :
Total Pages : 1242 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis Critical Care Nursing by : Linda Diann Urden

Download or read book Critical Care Nursing written by Linda Diann Urden and published by Saunders. This book was released on 2010 with total page 1242 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focusing on critical care nursing, this full-color text provides an examination of the important aspects of critical care nursing. It is organized in ten units around alterations in body systems.

Handbook of Biomedical Imaging

Author : Nikos Paragios
Publisher : Springer
ISBN 13 : 9781489977755
Total Pages : 0 pages
Book Rating : 4.9/5 (777 download)

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Book Synopsis Handbook of Biomedical Imaging by : Nikos Paragios

Download or read book Handbook of Biomedical Imaging written by Nikos Paragios and published by Springer. This book was released on 2016-10-05 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers a unique guide to the entire chain of biomedical imaging, explaining how image formation is done, and how the most appropriate algorithms are used to address demands and diagnoses. It is an exceptional tool for radiologists, research scientists, senior undergraduate and graduate students in health sciences and engineering, and university professors.

Phase I Cancer Clinical Trials

Author : Elizabeth A. Eisenhauer
Publisher : Oxford University Press, USA
ISBN 13 : 0199359016
Total Pages : 369 pages
Book Rating : 4.1/5 (993 download)

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Book Synopsis Phase I Cancer Clinical Trials by : Elizabeth A. Eisenhauer

Download or read book Phase I Cancer Clinical Trials written by Elizabeth A. Eisenhauer and published by Oxford University Press, USA. This book was released on 2014-06 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: Phase I trials are a critical first step in the study of novel cancer therapeutic approaches. As this title is the only comprehensive book on this topic, it is a useful resource for oncology trainees or specialists interested in understanding cancer drug development. New to this edition are chapters on Phase 0 Trials and Immunotherapeutics, and updated information on the process, pitfalls, and logistics of Phase I Trials.

Focal Therapy in Prostate Cancer

Author : Hashim Uddin Ahmed
Publisher : John Wiley & Sons
ISBN 13 : 1405196491
Total Pages : 213 pages
Book Rating : 4.4/5 (51 download)

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Book Synopsis Focal Therapy in Prostate Cancer by : Hashim Uddin Ahmed

Download or read book Focal Therapy in Prostate Cancer written by Hashim Uddin Ahmed and published by John Wiley & Sons. This book was released on 2011-12-27 with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book comprehensively reviews the potential of focal therapy and discusses why the changing face of prostate cancer warrants a change in the way we treat men with the disease. It deals with the mechanisms by which disease can be localized within the gland and then the different technologies used for focal ablation. Bringing together eminent contributors in one accessible reference, this book introduces focal therapy to all urologists, oncologists, and radiologists who are involved in the treatment of men with prostate cancer.

Gene Therapy of the Central Nervous System: From Bench to Bedside

Author : Michael G. Kaplitt
Publisher : Gulf Professional Publishing
ISBN 13 : 9780123976321
Total Pages : 380 pages
Book Rating : 4.9/5 (763 download)

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Book Synopsis Gene Therapy of the Central Nervous System: From Bench to Bedside by : Michael G. Kaplitt

Download or read book Gene Therapy of the Central Nervous System: From Bench to Bedside written by Michael G. Kaplitt and published by Gulf Professional Publishing. This book was released on 2006 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: Few areas of biomedical research provide greater opportunities to capitalize upon the revolution in genomics and molecular biology than gene therapy. This is particularly true for the brain and nervous system, where gene transfer has become a key technology for basic research and has recently been translated to human therapy in several landmark clinical trials. Gene Therapy in the Brain: From Bench to Bedside represents the definitive volume on this subject. Edited by two pioneers of neurological gene therapy, this volume contains contributions by leaders who helped to create the field as well as those who are expanding the promise of gene therapy for the future of basic and clinical neuroscience. Drawing upon this extensive collective experience, this book provides clear and informative reviews on a variety of subjects which would be of interest to anyone who is currently using or contemplating exploring gene therapy for neurobiological applications. Basic gene transfer technologies are discussed, with particular emphases upon novel vehicles, immunological issues and the role of gene therapy in stem cells. Numerous research applications are reviewed, particularly in complex fields such as behavioral neurobiology. Several preclinical areas are also covered which are likely to translate into clinical studies in the near future, including epilepsy, pain and amyotrophic lateral sclerosis. Among the most exciting advances in recent years has been the use of neurological gene therapy in human clinical trials, including Parkinson's disease, Canavan disease and Batten disease. Finally, readers will find "insider" information on technological and regulatory issues which can often limit effective translation of even the most promising idea into clinical use. This work provides up-to-date information and key insights into those gene therapy issues which are important to both scientists and clinicians focusing upon the brain and central nervous system.

The Patient Will See You Now

Author : Eric Topol
Publisher : Basic Books
ISBN 13 : 0465094473
Total Pages : 386 pages
Book Rating : 4.4/5 (65 download)

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Book Synopsis The Patient Will See You Now by : Eric Topol

Download or read book The Patient Will See You Now written by Eric Topol and published by Basic Books. This book was released on 2016-10-25 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: The essential guide by one of America's leading doctors to how digital technology enables all of us to take charge of our health A trip to the doctor is almost a guarantee of misery. You'll make an appointment months in advance. You'll probably wait for several hours until you hear "the doctor will see you now"-but only for fifteen minutes! Then you'll wait even longer for lab tests, the results of which you'll likely never see, unless they indicate further (and more invasive) tests, most of which will probably prove unnecessary (much like physicals themselves). And your bill will be astronomical. In The Patient Will See You Now, Eric Topol, one of the nation's top physicians, shows why medicine does not have to be that way. Instead, you could use your smartphone to get rapid test results from one drop of blood, monitor your vital signs both day and night, and use an artificially intelligent algorithm to receive a diagnosis without having to see a doctor, all at a small fraction of the cost imposed by our modern healthcare system. The change is powered by what Topol calls medicine's "Gutenberg moment." Much as the printing press took learning out of the hands of a priestly class, the mobile internet is doing the same for medicine, giving us unprecedented control over our healthcare. With smartphones in hand, we are no longer beholden to an impersonal and paternalistic system in which "doctor knows best." Medicine has been digitized, Topol argues; now it will be democratized. Computers will replace physicians for many diagnostic tasks, citizen science will give rise to citizen medicine, and enormous data sets will give us new means to attack conditions that have long been incurable. Massive, open, online medicine, where diagnostics are done by Facebook-like comparisons of medical profiles, will enable real-time, real-world research on massive populations. There's no doubt the path forward will be complicated: the medical establishment will resist these changes, and digitized medicine inevitably raises serious issues surrounding privacy. Nevertheless, the result-better, cheaper, and more human health care-will be worth it. Provocative and engrossing, The Patient Will See You Now is essential reading for anyone who thinks they deserve better health care. That is, for all of us.

Management of Portal Hypertension

Author : Peter Malfertheiner
Publisher : S. Karger AG (Switzerland)
ISBN 13 : 9783805579476
Total Pages : 0 pages
Book Rating : 4.5/5 (794 download)

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Book Synopsis Management of Portal Hypertension by : Peter Malfertheiner

Download or read book Management of Portal Hypertension written by Peter Malfertheiner and published by S. Karger AG (Switzerland). This book was released on 2005 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Digestive Diseases provides an update and progress report on the management of patients presenting with complications of portal hypertension. If interventional radiological and endoscopic as well as pharmacological treatment options fail, liver transplantation is the ultimate rescue which relieves portal hypertension, prevents variceal re-bleeding, and prevents ascites and encephalopathy by restoring liver function. The complex issues involved in the management of portal hypertension are presented in this publication in a complete and clear way, providing a wealth of information for the clinician.

Cancer Basics

Author : Julia Eggert
Publisher :
ISBN 13 : 9781890504908
Total Pages : 0 pages
Book Rating : 4.5/5 (49 download)

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Book Synopsis Cancer Basics by : Julia Eggert

Download or read book Cancer Basics written by Julia Eggert and published by . This book was released on 2010 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: From the foundations of cancer to issues of survivorship, this book provides all the details and information needed to gain a true understanding of the 'basics' of cancer.

Chemical Analysis

Author : Francis Rouessac
Publisher : John Wiley & Sons
ISBN 13 : 1118681878
Total Pages : 494 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Chemical Analysis by : Francis Rouessac

Download or read book Chemical Analysis written by Francis Rouessac and published by John Wiley & Sons. This book was released on 2013-05-06 with total page 494 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completely revised and updated, Chemical Analysis: Second Edition is an essential introduction to a wide range of analytical techniques and instruments. Assuming little in the way of prior knowledge, this text carefully guides the reader through the more widely used and important techniques, whilst avoiding excessive technical detail. Provides a thorough introduction to a wide range of the most important and widely used instrumental techniques Maintains a careful balance between depth and breadth of coverage Includes examples, problems and their solutions Includes coverage of latest developments including supercritical fluid chromatography and capillary electrophoresis

Major Problems in Developmental Biology

Author : Michael Locke
Publisher : Elsevier
ISBN 13 : 0323151132
Total Pages : 421 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis Major Problems in Developmental Biology by : Michael Locke

Download or read book Major Problems in Developmental Biology written by Michael Locke and published by Elsevier. This book was released on 2012-12-02 with total page 421 pages. Available in PDF, EPUB and Kindle. Book excerpt: Major Problems in Developmental Biology contains the proceedings of the 25th Symposium of the Society for Developmental Biology, held in Haverford, Pennsylvania, in June 1966. The papers explore some of the major problems in developmental biology, particularly those relating to cell differentiation, movements, and death; patterning; and intercellular regulation in plants. Organized into 11 chapters, this book begins with an overview of the growth and development of developmental biology as a scientific discipline, with emphasis on the role of the Society for Developmental Biology, and in particular its symposia, in the emergence of the field. The book then discusses the intra- and extracellular factors impinging upon the nucleus and regulating cell differentiation. Some chapters focus on the dynamics of determination in cell systems of insects, morphogenetic movements of animal cells, and patterns at the cell and tissue levels. The reader is also introduced to the correlations between protein structure and function in relation to cell dynamics and differentiation, along with the physiological, biochemical, and molecular biological aspects of intercellular regulation in plants and the role of cell surface in carcinogenesis. The book concludes by suggesting directions for research into the ontogeny of behavior. This book is a valuable source of information for developmental biologists.

Encyclopedia of AIDS

Author : Thomas J. Hope
Publisher :
ISBN 13 : 9781461496106
Total Pages : pages
Book Rating : 4.4/5 (961 download)

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Book Synopsis Encyclopedia of AIDS by : Thomas J. Hope

Download or read book Encyclopedia of AIDS written by Thomas J. Hope and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Biohydrogen

Author : Kuan-Yeow Show
Publisher : Elsevier Inc. Chapters
ISBN 13 : 0128083638
Total Pages : 39 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Biohydrogen by : Kuan-Yeow Show

Download or read book Biohydrogen written by Kuan-Yeow Show and published by Elsevier Inc. Chapters. This book was released on 2013-06-11 with total page 39 pages. Available in PDF, EPUB and Kindle. Book excerpt: In combating global warming and other environmental issues over the use of fossil fuels, extensive research has been focusing on developing hydrogen production from biological processes. Biohydrogen is considered a promising future biofuel because of its intrinsic clean and high-energy content properties and the way it is produced. In addition to being produced through environmentally friendly biological means, its conversion to energy yields only pure water, which is an ideal energy carrier in reducing greenhouse gas emissions from fossil fuel combustion. Unlike other well-developed biofuels such as bioethanol and biodiesel, biohydrogen production is still in the early stage of development. A variety of technologies are being developed for biohydrogen production. This chapter presents a review of the state-of-the-art and perspectives of bioprocess design for biohydrogen production research in the context of pathways, microorganisms, metabolic flux analysis, process design, and reactor system. Challenges and prospects of biohydrogen production are also outlined.

Human Anatomy

Author : Giuseppe Anastasi
Publisher :
ISBN 13 : 9788870517897
Total Pages : 0 pages
Book Rating : 4.5/5 (178 download)

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Book Synopsis Human Anatomy by : Giuseppe Anastasi

Download or read book Human Anatomy written by Giuseppe Anastasi and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Spine Oncology

Author : Onder Ofluoglu
Publisher : Clinics: Orthopedics
ISBN 13 : 9781437705140
Total Pages : 0 pages
Book Rating : 4.7/5 (51 download)

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Book Synopsis Spine Oncology by : Onder Ofluoglu

Download or read book Spine Oncology written by Onder Ofluoglu and published by Clinics: Orthopedics. This book was released on 2009 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Every Clinics issue brings you todayÆs best thinking on the challenges you face. Whether you purchase these issues individually, or order a personal subscription (which includes online access to current and past issues at www.theclinics.com), the Clinics offer you an efficient way to update your know howàone issue at a time. Book jacket.

Discover Biology

Author : Michael Lee Cain
Publisher : Sunderland, Mass. : Sinauer Associates
ISBN 13 : 9780393940558
Total Pages : 800 pages
Book Rating : 4.9/5 (45 download)

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Book Synopsis Discover Biology by : Michael Lee Cain

Download or read book Discover Biology written by Michael Lee Cain and published by Sunderland, Mass. : Sinauer Associates. This book was released on 2002 with total page 800 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thoroughly revised and updated, Discover Biology, Second Edition, presents the essential concepts of modern biology in a text designed specifically for nonmajors. The authors emphasize a level of detail appropriate for nonmajors, freeing instructors to focus on the scientific issues-HIV, global climate change, DNA fingerprinting, genetic engineering, cancer-that students read about in the paper, vote on in elections, and face in their daily lives. With two new chapters, refined pedagogy and art programs, and a powerful ancillary package, Discover Biology, Second Edition, is the best choice for the nonmajors introductory course.