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Author : Francisco Ciruela
Publisher : Frontiers Media SA
ISBN 13 : 283252575X
Total Pages : 187 pages
Book Rating : 4.8/5 (325 download)
Download or read book Purinergic pharmacology, volume II written by Francisco Ciruela and published by Frontiers Media SA. This book was released on 2023-06-07 with total page 187 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Harry Majewski
Publisher : EOLSS Publications
ISBN 13 : 184826254X
Total Pages : 428 pages
Book Rating : 4.8/5 (482 download)
Download or read book Pharmacology - Volume II written by Harry Majewski and published by EOLSS Publications. This book was released on 2009-10-29 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmacology is a component of Encyclopedia of Biological, Physiological and Health Sciences in the global Encyclopedia of Life Support Systems (EOLSS), which is an integrated compendium of twenty one Encyclopedias. Pharmacology is the study of the actions of chemicals on the body and most usually it is defined as chemicals that can have a therapeutic action to treat disease. Since it looks at the interaction between chemicals and body systems pharmacology utilizes the basic disciplines of chemistry, biochemistry, physiology, pathology and microbiology in its practice. Pharmacology is a foundation science for pharmacy which is the rational prescribing of drugs to treat disease and the foundation science for toxicology which is the study of the toxic actions of chemicals on the body. The two volumes are organized in groups of chapters as follows: The first group of chapters discuss pharmacological principles and these include chapters on Pharmacodynamics; Pharmacokinetics, Neuropharmacology, Autonomic Pharmacology and Clinical Pharmacology. The second group of chapters discusses the processes of Drug discovery and the Safety requirements for drugs to be used therapeutically and include Drug Discovery and Safety Pharmacology assessment. The largest group of chapters discuss different therapeutic areas and include Cardiovascular and renal pharmacology; Endocrine pharmacology; Neuropsychopharmacology; Pulmonary Pharmacology; Gastrointestinal pharmacology; Poisons venoms and toxins; Drugs on skeletal muscle; the Pharmacotherapy of inflammation; Reproductive pharmacology; Pain pharmacology and analgesia. The final group of chapters discuss new approaches and include Pharmacogenetics and pharmacogenomics; Immunopharmacology and Gene therapy. These two volumes are aimed at the following a wide spectrum of audiences from the merely curious to those seeking in-depth knowledge: University and College students Educators, Professional practitioners, Research personnel and Policy analysts, managers, and decision makers and NGOs.
Author : Francesco Clementi
Publisher : John Wiley & Sons
ISBN 13 : 1118768590
Total Pages : 784 pages
Book Rating : 4.1/5 (187 download)
Download or read book General and Molecular Pharmacology written by Francesco Clementi and published by John Wiley & Sons. This book was released on 2015-07-01 with total page 784 pages. Available in PDF, EPUB and Kindle. Book excerpt: With a focus on functional relationships between drugs and their targets, this book covers basic and general pharmacology, from a cellular and molecular perspective, with particular attention to the mechanisms of drug action – the fundamental basis for proper clinical use- without neglecting clinical application, toxicology and pharmacokinetics. • Covers cell and molecular pharmacology, bringing together current research on regulation of drug targets, at a level appropriate for advanced undergrad and graduate students • Discusses the relevance of pharmacokinetics and drug development for the clinical application of drugs • Presents material from the perspective of drug targets and interaction, the theoretical basis of drug action analysis, and drug properties • Focuses on structure-function relationships of drug targets – informing about their biochemical and physiologic functions and experimental and clinical pathways for drug discovery and development • Has a companion website that offers a host of resources: short additional chapters about methodology, topics at the forefront of research, and all figures and tables from the book
Author : James M. Ritter
Publisher : Elsevier Health Sciences
ISBN 13 : 0702074462
Total Pages : 809 pages
Book Rating : 4.7/5 (2 download)
Download or read book Rang & Dale's Pharmacology written by James M. Ritter and published by Elsevier Health Sciences. This book was released on 2018-11-04 with total page 809 pages. Available in PDF, EPUB and Kindle. Book excerpt: World-renowned coverage of today's pharmacology at your fingertips - Keeps you up-to-date with new information in this fast-changing field, including significantly revised coverage of CNS drugs, cognitive enhancers, anti-infectives, biologicals/biopharmaceuticals, lifestyle drugs, and more. - Includes access to unique features, including more than 100 brand new chapter-specific multiple-choice questions and 6 new cases for immediate self-assessment. - Features a color-coded layout for faster navigation and cross-referencing. - Clarifies complex concepts with Key Points boxes, Clinical Uses boxes and full-color illustrations throughout.
Author : Robson Faria
Publisher : BoD – Books on Demand
ISBN 13 : 1789845343
Total Pages : 112 pages
Book Rating : 4.7/5 (898 download)
Download or read book Receptors P1 and P2 as Targets for Drug Therapy in Humans written by Robson Faria and published by BoD – Books on Demand. This book was released on 2020-03-11 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book aims to provide a brief update on the functions of purinergic receptors in various systems, in addition to the signaling pathway activated to mediate these functions. We address the influence of hypoxia by modulating the activity of these receptors under physiological and pathophysiological conditions. Additionally, we describe the mechanisms of induction of pain and inflammation in different systems. Finally, the book discusses some of the main bioinformatics tools currently used to improve or discover new prototypes capable of selectively acting on these receptors with estimated parameters of satisfactory solubility and toxicity for possible commercial implementation.
Author : Francisco Ciruela
Publisher : Frontiers Media SA
ISBN 13 : 2889459470
Total Pages : 852 pages
Book Rating : 4.8/5 (894 download)
Download or read book Purinergic Pharmacology written by Francisco Ciruela and published by Frontiers Media SA. This book was released on 2019-08-16 with total page 852 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Leslie Iversen
Publisher : Oxford University Press
ISBN 13 : 0195380533
Total Pages : 568 pages
Book Rating : 4.1/5 (953 download)
Download or read book Introduction to Neuropsychopharmacology written by Leslie Iversen and published by Oxford University Press. This book was released on 2009 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt: The text ranges from drugs that affect the mood and behavior to hypnotics, narcotics, anticonvulsants, and analgesics, as well as a variety of drugs that affect the autonomic nervous system and psychoactive drugs used for non-medical reasons - nicotine, alcohol, opiates, psychostimulants and cannabis."--BOOK JACKET.
Author :
Publisher : Academic Press
ISBN 13 : 0123855330
Total Pages : 558 pages
Book Rating : 4.1/5 (238 download)
Download or read book Pharmacology of Purine and Pyrimidine Receptors written by and published by Academic Press. This book was released on 2011-07-13 with total page 558 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is an overview of the fast-moving field of purinergic signalling through adenosine and ATP receptors. - Authors are the leading authorities in their fields - Subject matter is important for understanding tissue protection - Subject matter is of intense interest for new drug development
Author : Maria P. Abracchio
Publisher : Springer Science & Business Media
ISBN 13 : 3642569218
Total Pages : 459 pages
Book Rating : 4.6/5 (425 download)
Download or read book Purinergic and Pyrimidinergic Signalling II written by Maria P. Abracchio and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 459 pages. Available in PDF, EPUB and Kindle. Book excerpt: Physiological, pharmacological and molecular biological data generated over the past three decades have demonstrated the existence of two major families of extracellular receptors, the P1, a family of four G-protein coupled receptors and the P2, a family of at least 12 receptors responsive to purine (ATP, ADP) and pyrimidine (UTP) nucleotides through which adenosine and ATP can function as extracellular messengers. The present two-part volume represents an integrated compendium of invited chapters by leading researchers in the area focusing on advances in the understanding of purinergic and pyrimidinergic signaling systems, their role(s) in tissue function and pathophysiology and advances in developing potential new medications based on the modulation of P1 and P2 receptor signaling processes. The volumes will thus provide the reader with a topical, comprehensive and integrated overview of this important area.
Author :
Publisher : Elsevier
ISBN 13 : 0080490972
Total Pages : 531 pages
Book Rating : 4.0/5 (84 download)
Download or read book Extracellular Nucleotides and Nucleosides: Release, Receptors, and Physiological & Pathophysiological Effects written by and published by Elsevier. This book was released on 2003-09-10 with total page 531 pages. Available in PDF, EPUB and Kindle. Book excerpt: Purinergic receptors are proteins that bind ATP as their extracellular ligand. Once thought only as an intracellular molecule that provides energy, ATP is also now considered an essential autocrine/paracrine agonist that acts extracellularly within tissues and tissue microenvironments. Receptors for ATP and its metabolites, so-called "purinergic receptors," are essential membrane receptors that transduce the extracellular signal carried by ATP. Many cell types or tissues express multiple types of these receptors, often on the same cell. This volume will cover the history and overall impact of extracellular ATP signaling, methods to detect ATP release and signaling, the molecular and cell biology of purinergic receptors, the pharmacology of purinergic receptors, the ion channel biophysics and biochemistry of P2X purinergic receptor channels, and the physiology and pathophysiology of purinergic receptors.Key Features* Organized and written by world-renowned experts* Covers state-of-the-art experimental methods* Has broad appeal to basic and clinical scientists, the biotch industry and pharmaceutical research companies
Author : Hans Vogel
Publisher : Springer Science & Business Media
ISBN 13 : 3540714200
Total Pages : 2118 pages
Book Rating : 4.5/5 (47 download)
Download or read book Drug Discovery and Evaluation: Pharmacological Assays written by Hans Vogel and published by Springer Science & Business Media. This book was released on 2007-10-30 with total page 2118 pages. Available in PDF, EPUB and Kindle. Book excerpt: The new edition of this successful reference offers both cutting-edge and classic pharmacological methods. Thoroughly revised and expanded to two volumes, it offers an updated selection of the most frequently used assays for reliably detecting the pharmacological effects of potential drugs. Every chapter has been updated, and numerous assays have been added. Each of the more than 1,000 assays comprises a detailed protocol outlining purpose and rationale, and a critical assessment of the results and their pharmacological and clinical relevance.
Author : Kenneth L. Davis
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 9780781728379
Total Pages : 1964 pages
Book Rating : 4.7/5 (283 download)
Download or read book Neuropsychopharmacology written by Kenneth L. Davis and published by Lippincott Williams & Wilkins. This book was released on 2002 with total page 1964 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thoroughly updated and completely reorganized for a sharper clinical focus, the Fifth Edition of this world-renowned classic synthesizes the latest advances in basic neurobiology, biological psychiatry, and clinical neuropsychopharmacology. The book establishes a critical bridge connecting new discoveries in molecular and cellular biology, genetics, and neuroimaging with the etiology, diagnosis, and treatment of all neuropsychiatric disorders. Nine sections focus on specific groups of disorders, covering clinical course, genetics, neurobiology, neuroimaging, and current and emerging therapeutics. Four sections cover neurotransmitter and signal transduction, emerging methods in molecular biology and genetics, emerging imaging technologies and their psychiatric applications, and drug discovery and evaluation. Compatibility: BlackBerry(R) OS 4.1 or Higher / iPhone/iPod Touch 2.0 or Higher /Palm OS 3.5 or higher / Palm Pre Classic / Symbian S60, 3rd edition (Nokia) / Windows Mobile(TM) Pocket PC (all versions) / Windows Mobile Smartphone / Windows 98SE/2000/ME/XP/Vista/Tablet PC
Author : Alex S. Evers
Publisher : Cambridge University Press
ISBN 13 : 1139497022
Total Pages : 2902 pages
Book Rating : 4.1/5 (394 download)
Download or read book Anesthetic Pharmacology written by Alex S. Evers and published by Cambridge University Press. This book was released on 2011-03-10 with total page 2902 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years our understanding of molecular mechanisms of drug action and interindividual variability in drug response has grown enormously. Meanwhile, the practice of anesthesiology has expanded to the preoperative environment and numerous locations outside the OR. Anesthetic Pharmacology: Basic Principles and Clinical Practice, 2nd edition, is an outstanding therapeutic resource in anesthesia and critical care: Section 1 introduces the principles of drug action, Section 2 presents the molecular, cellular and integrated physiology of the target organ/functional system and Section 3 reviews the pharmacology and toxicology of anesthetic drugs. The new Section 4, Therapeutics of Clinical Practice, provides integrated and comparative pharmacology and the practical application of drugs in daily clinical practice. Edited by three highly acclaimed academic anesthetic pharmacologists, with contributions from an international team of experts, and illustrated in full colour, this is a sophisticated, user-friendly resource for all practitioners providing care in the perioperative period.
Author : Derek J. Chadwick
Publisher : John Wiley & Sons
ISBN 13 : 0470514914
Total Pages : 346 pages
Book Rating : 4.4/5 (75 download)
Download or read book P2 Purinoceptors written by Derek J. Chadwick and published by John Wiley & Sons. This book was released on 2008-04-30 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many different pathological conditions are currently under investigation as therapeutic targets of purines including cancer, cardiovascular conditions, behavioural disorders, inflammation, immunoregulation, and neuroendocrine function. This book draws together research on all aspects of P2 purinoceptors and discusses their use in different therapeutic areas.
Author : Gonzalo E. Yevenes
Publisher : Frontiers Media SA
ISBN 13 : 2889663981
Total Pages : 377 pages
Book Rating : 4.8/5 (896 download)
Download or read book Celebrating 40 Years of the Chilean Society of Pharmacology written by Gonzalo E. Yevenes and published by Frontiers Media SA. This book was released on 2021-01-19 with total page 377 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Geoffrey Burnstock
Publisher : Springer Science & Business Media
ISBN 13 : 3642288634
Total Pages : 724 pages
Book Rating : 4.6/5 (422 download)
Download or read book Purinergic Signalling and the Nervous System written by Geoffrey Burnstock and published by Springer Science & Business Media. This book was released on 2012-06-05 with total page 724 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the first 20 years that followed the purinergic signalling hypothesis in 1972, most scientists were sceptical about its validity, largely because ATP was so well established as an intracellular molecule involved in cell biochemistry and it seemed unlikely that such a ubiquitous molecule would act as an extracellular signalling molecule. However, after the receptors for ATP and adenosine were cloned and characterized in the early 1990s and ATP was established as a synaptic transmitter in the brain and sympathetic ganglia, the tide turned. More recently it has become clear that ATP is involved in long-term (trophic) signalling in cell proliferation, differentiation and death, in development and regeneration, as well as in short-term signalling in neurotransmission and secretion. Also, important papers have been published showing the molecular structure of P2X receptors in primitive animals like Amoeba and Schistosoma, as well as green algae. This has led to the recognition of the widespread nature of the purinergic signalling system in most cell types and to a rapid expansion of the field, including studies of the pathophysiology as well as physiology and exploration of the therapeutic potential of purinergic agents. In two books, Geoffrey Burnstock and Alexej Verkhratsky have aimed at drawing together the massive and diverse body of literature on purinergic signalling. The topic of this first book is purinergic signalling in the peripheral and central nervous systems and in the individual senses. In a second book the authors focus on purinergic signalling in non-excitable cells, including those of the airways, kidney, pancreas, endocrine glands and blood vessels. Diseases related to these systems are also considered.
Author : Stefan Offermanns
Publisher : Springer Science & Business Media
ISBN 13 : 3540389164
Total Pages : 1515 pages
Book Rating : 4.5/5 (43 download)
Download or read book Encyclopedia of Molecular Pharmacology written by Stefan Offermanns and published by Springer Science & Business Media. This book was released on 2008-08-14 with total page 1515 pages. Available in PDF, EPUB and Kindle. Book excerpt: An essential text, this is a fully updated second edition of a classic, now in two volumes. It provides rapid access to information on molecular pharmacology for research scientists, clinicians and advanced students. With the A-Z format of over 2,000 entries, around 350 authors provide a complete reference to the area of molecular pharmacology. The book combines the knowledge of classic pharmacology with the more recent approach of the precise analysis of the molecular mechanisms by which drugs exert their effects. Short keyword entries define common acronyms, terms and phrases. In addition, detailed essays provide in-depth information on drugs, cellular processes, molecular targets, techniques, molecular mechanisms, and general principles.
