Protein Structural Biology In Biomedical Research

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Protein Structural Biology in Biomedical Research, Part A

Author : C. Woodward
Publisher : Elsevier
ISBN 13 : 0080877052
Total Pages : 361 pages
Book Rating : 4.0/5 (88 download)

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Book Synopsis Protein Structural Biology in Biomedical Research, Part A by : C. Woodward

Download or read book Protein Structural Biology in Biomedical Research, Part A written by C. Woodward and published by Elsevier. This book was released on 1998-01-16 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent advances in protein structural biology, coupled with new developments in human genetics, have opened the door to understanding the molecular basis of many metabolic, physiological, and developmental processes in human biology. Medical pathologies, and their chemical therapies, are increasingly being described at the molecular level. For single-gene diseases, and some multi-gene conditions, identification of highly correlated genes immediately leads to identification of covalent structures of the actual chemical agents of the disease, namely the protein gene products. Once the primary sequence of a protein is ascertained, structural biologists work to determine its three-dimensional, biologically active structure, or to predict its probable fold and/or function by comparison to the data base of known protein structures. Similarly, three-dimensional structures of proteins produced by microbiological pathogens are the subject of intense study, for example, the proteins necessary for maturation of the human HIV virus. Once the three-dimensional structure of a protein is known or predicted, its function, as well as potential binding sites for drugs that inhibit its function, become tractable questions. The medical ramifications of the burgeoning results of protein structural biology, from gene replacement therapy to "rational" drug design, are well recognized by researchers in biomedical areas, and by a significant proportion of the general population. The purpose of this book is to introduce biomedical scientists to important areas of protein structural biology, and to provide an insightful orientation to the primary literature that shapes the field in each subject. The chapters in this volume cover aspects of protein structural biology which have led to the recognition of fundamental relationships between protein structure and function.

Protein Structural Biology in Biomedical Research

Author :
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (382 download)

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Download or read book Protein Structural Biology in Biomedical Research written by and published by . This book was released on 1997 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Protein Structural Biology in Biomedical Research

Author :
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (91 download)

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Download or read book Protein Structural Biology in Biomedical Research written by and published by . This book was released on 1997 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Protein Structural Biology in Biomedical Research

Author :
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (382 download)

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Protein Structural Biology in Biomedical Research, Part A

Author : C. Woodward
Publisher : Elsevier Science
ISBN 13 : 9780762302833
Total Pages : 626 pages
Book Rating : 4.3/5 (28 download)

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Book Synopsis Protein Structural Biology in Biomedical Research, Part A by : C. Woodward

Download or read book Protein Structural Biology in Biomedical Research, Part A written by C. Woodward and published by Elsevier Science. This book was released on 1998-01-30 with total page 626 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent advances in protein structural biology, coupled with new developments in human genetics, have opened the door to understanding the molecular basis of many metabolic, physiological, and developmental processes in human biology. Medical pathologies, and their chemical therapies, are increasingly being described at the molecular level. For single-gene diseases, and some multi-gene conditions, identification of highly correlated genes immediately leads to identification of covalent structures of the actual chemical agents of the disease, namely the protein gene products. Once the primary sequence of a protein is ascertained, structural biologists work to determine its three-dimensional, biologically active structure, or to predict its probable fold and/or function by comparison to the data base of known protein structures. Similarly, three-dimensional structures of proteins produced by microbiological pathogens are the subject of intense study, for example, the proteins necessary for maturation of the human HIV virus. Once the three-dimensional structure of a protein is known or predicted, its function, as well as potential binding sites for drugs that inhibit its function, become tractable questions. The medical ramifications of the burgeoning results of protein structural biology, from gene replacement therapy to "rational" drug design, are well recognized by researchers in biomedical areas, and by a significant proportion of the general population. The purpose of this book is to introduce biomedical scientists to important areas of protein structural biology, and to provide an insightful orientation to the primary literature that shapes the field in each subject. The chapters in this volume cover aspects of protein structural biology which have led to the recognition of fundamental relationships between protein structure and function.

Protein Structural Biology in Biomedical Research

Author :
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (382 download)

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Book Synopsis Protein Structural Biology in Biomedical Research by :

Molecular Biology of The Cell

Author : Bruce Alberts
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

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Book Synopsis Molecular Biology of The Cell by : Bruce Alberts

Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Advances in Molecular and Cell Biology

Author : E. Edward Bittar
Publisher :
ISBN 13 :
Total Pages : 337 pages
Book Rating : 4.:/5 (113 download)

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Book Synopsis Advances in Molecular and Cell Biology by : E. Edward Bittar

Download or read book Advances in Molecular and Cell Biology written by E. Edward Bittar and published by . This book was released on 1997 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent advances in protein structural biology, coupled with new developments in human genetics, have opened the door to understanding the molecular basis of many metabolic, physiological, and developmental processes in human biology. Medical pathologies, and their chemical therapies, are increasingly being described at the molecular level. For single-gene diseases, and some multi-gene conditions, identification of highly correlated genes immediately leads to identification of covalent structures of the actual chemical agents of the disease, namely the protein gene products. Once the primary sequence of a protein is ascertained, structural biologists work to determine its three-dimensional, biologically active structure, or to predict its probable fold and/or function by comparison to the data base of known protein structures. Similarly, three-dimensional structures of proteins produced by microbiological pathogens are the subject of intense study, for example, the proteins necessary for maturation of the human HIV virus. Once the three-dimensional structure of a protein is known or predicted, its function, as well as potential binding sites for drugs that inhibit its function, become tractable questions. The medical ramifications of the burgeoning results of protein structural biology, from gene replacement therapy to "rational" drug design, are well recognized by researchers in biomedical areas, and by a significant proportion of the general population. The purpose of this book is to introduce biomedical scientists to important areas of protein structural biology, and to provide an insightful orientation to the primary literature that shapes the field in each subject. The chapters in this volume cover aspects of protein structural biology which have led to the recognition of fundamental relationships between protein structure and function.

Computational Structural Biology

Author : Torsten Schwede
Publisher : World Scientific
ISBN 13 : 9812778780
Total Pages : 790 pages
Book Rating : 4.8/5 (127 download)

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Book Synopsis Computational Structural Biology by : Torsten Schwede

Download or read book Computational Structural Biology written by Torsten Schwede and published by World Scientific. This book was released on 2008 with total page 790 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a comprehensive introduction to Landau-Lifshitz equations and Landau-Lifshitz-Maxwell equations, beginning with the work by Yulin Zhou and Boling Guo in the early 1980s and including most of the work done by this Chinese group led by Zhou and Guo since. The book focuses on aspects such as the existence of weak solutions in multi dimensions, existence and uniqueness of smooth solutions in one dimension, relations with harmonic map heat flows, partial regularity and long time behaviors. The book is a valuable reference book for those who are interested in partial differential equations, geometric analysis and mathematical physics. It may also be used as an advanced textbook by graduate students in these fields.

Computational Structural Biology

Author : Manuel Claude Peitsch
Publisher : World Scientific
ISBN 13 : 9812778772
Total Pages : 790 pages
Book Rating : 4.8/5 (127 download)

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Book Synopsis Computational Structural Biology by : Manuel Claude Peitsch

Download or read book Computational Structural Biology written by Manuel Claude Peitsch and published by World Scientific. This book was released on 2008 with total page 790 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work covers the impact of computational structural biology on protein structure prediction methods, macromolecular function and protein design, and key methods in drug discovery. It also addresses the computational challenges of experimental approaches in structural biology.

Proteins

Author : Jia-huai Wang
Publisher : Elsevier
ISBN 13 : 0323999506
Total Pages : 0 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Proteins by : Jia-huai Wang

Download or read book Proteins written by Jia-huai Wang and published by Elsevier. This book was released on 2024-09-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proteins: A Structural Biology Perspective covers basic concepts of protein science that is illustrated by practical examples. The book will help biologists bear in mind that to investigate the molecular mechanism of the biological system they have been working on, one should always seek the answer from structural perspective. The book also helps structural biologists and students in the structure field to be aware that a protein structure is a beautiful result of the long molecular evolution. The book focuses on two points: from genomic perspective and from protein-protein interaction view of protein structures. Features some basic concepts of protein science as illustrated by practical examples Helps biologists bear in mind that to investigate the molecular mechanism of the biological system they have been working on, one should always seek the answer from structural perspective Aids structural biologists and students in the structure field to be aware of the structure of proteins Focuses on two points: From a genomic perspective and from a protein-protein interaction view of protein structures

Exploring Protein Structure: Principles and Practice

Author : Tim Skern
Publisher : Springer
ISBN 13 : 3319768581
Total Pages : 255 pages
Book Rating : 4.3/5 (197 download)

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Book Synopsis Exploring Protein Structure: Principles and Practice by : Tim Skern

Download or read book Exploring Protein Structure: Principles and Practice written by Tim Skern and published by Springer. This book was released on 2018-07-04 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook introduces the basics of protein structure and logically explains how to use online software to explore the information in protein structure databases. Readers will find easily understandable, step-by step exercises and video-trainings to support them in grasping the fundamental concepts. After reading this book, readers will have the skills required to independently explore and analyze macromolecular structures, will be versed in extracting information from protein databases and will be able to visualize protein structures using specialized software and on-line algorithms. This book is written for advanced undergraduates and PhD students wishing to use information from structural biology in their assignments and research and will be a valuable source of information for all those interested in applied and theoretical aspects of structural biology.

Protein Structure

Author : Daniel Chasman
Publisher : CRC Press
ISBN 13 : 0824748166
Total Pages : 534 pages
Book Rating : 4.8/5 (247 download)

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Book Synopsis Protein Structure by : Daniel Chasman

Download or read book Protein Structure written by Daniel Chasman and published by CRC Press. This book was released on 2003-03-18 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text offers in-depth perspectives on every aspect of protein structure identification, assessment, characterization, and utilization, for a clear understanding of the diversity of protein shapes, variations in protein function, and structure-based drug design. The authors cover numerous high-throughput technologies as well as computational methods to study protein structures and residues. A valuable reference, this book reflects current trends in the effort to solve new structures arising from genome initiatives, details methods to detect and identify errors in the prediction of protein structural models, and outlines challenges in the conversion of routine processes into high-throughput platforms.

Structural Biology and Functional Genomics

Author : E. Morton Bradbury
Publisher : Springer Science & Business Media
ISBN 13 : 9401146314
Total Pages : 311 pages
Book Rating : 4.4/5 (11 download)

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Book Synopsis Structural Biology and Functional Genomics by : E. Morton Bradbury

Download or read book Structural Biology and Functional Genomics written by E. Morton Bradbury and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomedical research will be revolutionised by the current efforts to sequence the human genome and the genomes of model organisms. Of the newly sequenced genes, 50% code for proteins of unknown functions, while as little as 5% of sequences in mammalian genomes code for proteins. New, genome-wide approaches are needed to draw together the knowledge that is emerging simultaneously in a number of fields of genome research. This volume is a high-level survey of the newly emerging concepts of structural biology and functional genomics for biologists, biochemists and medical researchers interested in genome research. Topics included are chromosome and chromatin organisation, novel DNA and RNA structures, DNA flexibility, supercoiling, prediction of protein functions, strategies for large scale structural analysis, and computer modelling.

Advances in Protein Molecular and Structural Biology Methods

Author : Timir Tripathi
Publisher : Academic Press
ISBN 13 : 0323902650
Total Pages : 716 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Advances in Protein Molecular and Structural Biology Methods by : Timir Tripathi

Download or read book Advances in Protein Molecular and Structural Biology Methods written by Timir Tripathi and published by Academic Press. This book was released on 2022-01-14 with total page 716 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Protein Molecular and Structural Biology Methods offers a complete overview of the latest tools and methods applicable to the study of proteins at the molecular and structural level. The book begins with sections exploring tools to optimize recombinant protein expression and biophysical techniques such as fluorescence spectroscopy, NMR, mass spectrometry, cryo-electron microscopy, and X-ray crystallography. It then moves towards computational approaches, considering structural bioinformatics, molecular dynamics simulations, and deep machine learning technologies. The book also covers methods applied to intrinsically disordered proteins (IDPs)followed by chapters on protein interaction networks, protein function, and protein design and engineering. It provides researchers with an extensive toolkit of methods and techniques to draw from when conducting their own experimental work, taking them from foundational concepts to practical application. Presents a thorough overview of the latest and emerging methods and technologies for protein study Explores biophysical techniques, including nuclear magnetic resonance, X-ray crystallography, and cryo-electron microscopy Includes computational and machine learning methods Features a section dedicated to tools and techniques specific to studying intrinsically disordered proteins

Structural Genomics and High Throughput Structural Biology

Author : Michael Sundstrom
Publisher : CRC Press
ISBN 13 : 0849361435
Total Pages : 304 pages
Book Rating : 4.8/5 (493 download)

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Book Synopsis Structural Genomics and High Throughput Structural Biology by : Michael Sundstrom

Download or read book Structural Genomics and High Throughput Structural Biology written by Michael Sundstrom and published by CRC Press. This book was released on 2005-08-23 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: Researchers in structural genomics continue to search for biochemical and cellular functions of proteins as well as the ways in which proteins assemble into functional pathways and networks using either experimental or computational approaches. Based on the experience of leading international experts, Structural Genomics and High Throughput Stru

Protein Structure and Modeling

Author : Natalya Kurochkina
Publisher : Springer
ISBN 13 : 9811366012
Total Pages : 276 pages
Book Rating : 4.8/5 (113 download)

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Book Synopsis Protein Structure and Modeling by : Natalya Kurochkina

Download or read book Protein Structure and Modeling written by Natalya Kurochkina and published by Springer. This book was released on 2019-06-04 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book will consider principles of the organization of protein molecules, the relationships between primary, secondary, and tertiary structure, the determinants of protein conformation, and the applications of structure determination and structure modeling in biomedical research.