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Protein Engineering And Design
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Book Synopsis Protein Engineering and Design by : Sheldon J. Park
Download or read book Protein Engineering and Design written by Sheldon J. Park and published by CRC Press. This book was released on 2009-09-25 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: Experimental protein engineering and computational protein design are broad but complementary strategies for developing proteins with altered or novel structural properties and biological functions. By describing cutting-edge advances in both of these fields, Protein Engineering and Design aims to cultivate a synergistic approach to protein science
Book Synopsis Protein Engineering and Design by : Paul R. Carey
Download or read book Protein Engineering and Design written by Paul R. Carey and published by Elsevier. This book was released on 1996-06-21 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: The design and production of novel peptides and proteins occupy pivotal positions in science and technology and will continue to do so in the 21st century. Protein Engineering and Design outlines the rapid advances in computer-based modeling, protein engineering, and methods needed for protein and peptide preparation and characterization. This indispensable reference lays the groundwork for understanding this multidisciplinary activity while providing an introduction for researchers and students to the field of protein design. Introduces and defines the techniques involved in protein engineering and design Provides a concise overview of key technologies involved and demonstrates their contributions to the specialized design and production of novel proteins and peptides
Book Synopsis Protein Engineering by : Huimin Zhao
Download or read book Protein Engineering written by Huimin Zhao and published by John Wiley & Sons. This book was released on 2021-08-23 with total page 41 pages. Available in PDF, EPUB and Kindle. Book excerpt: A one-stop reference that reviews protein design strategies to applications in industrial and medical biotechnology Protein Engineering: Tools and Applications is a comprehensive resource that offers a systematic and comprehensive review of the most recent advances in the field, and contains detailed information on the methodologies and strategies behind these approaches. The authors—noted experts on the topic—explore the distinctive advantages and disadvantages of the presented methodologies and strategies in a targeted and focused manner that allows for the adaptation and implementation of the strategies for new applications. The book contains information on the directed evolution, rational design, and semi-rational design of proteins and offers a review of the most recent applications in industrial and medical biotechnology. This important book: Covers technologies and methodologies used in protein engineering Includes the strategies behind the approaches, designed to help with the adaptation and implementation of these strategies for new applications Offers a comprehensive and thorough treatment of protein engineering from primary strategies to applications in industrial and medical biotechnology Presents cutting edge advances in the continuously evolving field of protein engineering Written for students and professionals of bioengineering, biotechnology, biochemistry, Protein Engineering: Tools and Applications offers an essential resource to the design strategies in protein engineering and reviews recent applications.
Book Synopsis A Practical Guide to Protein Engineering by : Tuck Seng Wong
Download or read book A Practical Guide to Protein Engineering written by Tuck Seng Wong and published by Springer Nature. This book was released on 2020-10-29 with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook introduces readers in an accessible and engaging way to the nuts and bolts of protein expression and engineering. Various case studies illustrate each step from the early sequence searches in online databases over plasmid design and molecular cloning techniques to protein purification and characterization. Furthermore, readers are provided with practical tips to successfully pursue a career as a protein engineer. With protein engineering being a fundamental technique in almost all molecular biology labs, the book targets advanced undergraduates and graduate students working in molecular biology, biotechnology and related scientific fields.
Book Synopsis Protein Engineering by : Mallorie N. Sheehan
Download or read book Protein Engineering written by Mallorie N. Sheehan and published by Nova Science Publishers. This book was released on 2013-07 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Protein engineering is the process of developing useful or valuable proteins. It is a young discipline, with much research currently taking place into the understanding of protein folding and protein recognition for protein design principles. There are two general strategies for protein engineering. The first is known as rational design, in which the scientist uses detailed knowledge of the structure and function of the protein to make desired changes. The second strategy is known as directed evolution and this is where random mutagenesis is applied to a protein, and a selection regime is used to pick out variants that have the desired qualities. This book presents and reviews important data on protein engineering, such as application of engineered proteins and cell adhesive surfaces as scaffolds or other biomedical devices which has the potential to promote tissue repair and regeneration for a wide variety of tissues including bone and skin.
Book Synopsis Medicinal Protein Engineering by : Yury E. Khudyakov
Download or read book Medicinal Protein Engineering written by Yury E. Khudyakov and published by CRC Press. This book was released on 2008-12-01 with total page 584 pages. Available in PDF, EPUB and Kindle. Book excerpt: An All-Inclusive Review of the Achievements and Trends in the Fast-Growing Protein Engineering Field From humble beginnings like making fire for mere survival, engineering now steadfastly penetrates all aspects of our lives and even life itself at the molecular level. Protein engineering is a molecular biological discipline focused on designing and constructing novel proteins with desired properties. The currently limited understanding of the relationship between protein structure and function greatly hinders rational protein design. However, despite great challenges, protein engineering has become a major molecular discipline with a large array of successful applications to many complex medicinal problems. Medicinal Protein Engineering sheds light on this largely unchartered field, covering major strategies for engineering of proteins with predetermined biological properties. It discusses computational approaches to protein design and experimental approaches to protein construction. This volume also explores the tight connection between protein and genetic engineering. It moves researchers beyond experimental protein construction and theoretical protein design to the medicinal applications of engineered proteins. Examines Medicinal Applications of Protein Engineering for the Diagnosis, Treatment, and Prevention of Diseases Focusing on the application of protein engineering to medicine, this seminal work outlines the appropriate techniques for studying protein properties and building mathematical engineering models of novel vaccines, diagnostic reagents, and therapeutic treatments. As a truly comprehensive assessment of the medical protein engineering research available and its future implications for disease control and prevention, this is an indispensable reference for biological researchers in this groundbreaking field.
Book Synopsis Computational Protein Design by : Ilan Samish
Download or read book Computational Protein Design written by Ilan Samish and published by Humana. This book was released on 2016-12-03 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim this volume is to present the methods, challenges, software, and applications of this widespread and yet still evolving and maturing field. Computational Protein Design, the first book with this title, guides readers through computational protein design approaches, software and tailored solutions to specific case-study targets. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Computational Protein Design aims to ensure successful results in the further study of this vital field.
Book Synopsis Concepts in Protein Engineering and Design by : Paul Wrede
Download or read book Concepts in Protein Engineering and Design written by Paul Wrede and published by de Gruyter. This book was released on 1994 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: No detailed description available for "Concepts in Protein Engineering and Design".
Book Synopsis Protein Engineering Techniques by : Krishna Mohan Poluri
Download or read book Protein Engineering Techniques written by Krishna Mohan Poluri and published by Springer. This book was released on 2016-11-12 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt: This brief provides a broad overview of protein-engineering research, offering a glimpse of the most common experimental methods. It also presents various computational programs with applications that are widely used in directed evolution, computational and de novo protein design. Further, it sheds light on the advantages and pitfalls of existing methodologies and future perspectives of protein engineering techniques.
Book Synopsis Engineering the Genetic Code by : Nediljko Budisa
Download or read book Engineering the Genetic Code written by Nediljko Budisa and published by John Wiley & Sons. This book was released on 2006-05-12 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ability to introduce non-canonical amino acids in vivo has greatly expanded the repertoire of accessible proteins for basic research and biotechnological application. Here, the different methods and strategies to incorporate new or modified amino acids are explained in detail, including a lot of practical advice for first-time users of this powerful technique. Novel applications in protein biochemistry, genomics, biotechnology and biomedicine made possible by the expansion of the genetic code are discussed and numerous examples are given. Essential reading for all molecular life scientists who want to stay ahead in their research.
Book Synopsis Protein Engineering Protocols by : Kristian Müller
Download or read book Protein Engineering Protocols written by Kristian Müller and published by Springer Science & Business Media. This book was released on 2007-10-26 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: Protein engineering is a fascinating mixture of molecular biology, protein structure analysis, computation, and biochemistry, with the goal of developing useful or valuable proteins. Protein Engineering Protocols will consider the two general, but not mutually exclusive, strategies for protein engineering. The first is known as rational design, in which the scientist uses detailed knowledge of the structure and function of the protein to make desired changes. The s- ond strategy is known as directed evolution. In this case, random mutagenesis is applied to a protein, and selection or screening is used to pick out variants that have the desired qualities. By several rounds of mutation and selection, this method mimics natural evolution. An additional technique known as DNA shuffling mixes and matches pieces of successful variants to produce better results. This process mimics recombination that occurs naturally during sexual reproduction. The first section of Protein Engineering Protocols describes rational p- tein design strategies, including computational methods, the use of non-natural amino acids to expand the biological alphabet, as well as impressive examples for the generation of proteins with novel characteristics. Although procedures for the introduction of mutations have become routine, predicting and und- standing the effects of these mutations can be very challenging and requires profound knowledge of the system as well as protein structures in general.
Book Synopsis Protein Engineering by : Uwe T. Bornscheuer
Download or read book Protein Engineering written by Uwe T. Bornscheuer and published by Humana Press. This book was released on 2017-10-30 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume details basic and advanced protocols for both stages of protein engineering: the library design phase and the identification of improved variants by screening and selection. Chapters focus on enzyme engineering using rational and semi-rational approaches. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Protein Engineering: Methods and Protocols aims to aid scientists in the planning and performance of their experiments. The chapter 'Functional Analysis of Membrane Proteins Produced by Cell-Free Translation' is open access under a CC BY 4.0 license via link.springer.com.
Book Synopsis Concepts in Protein Engineering and Design by : Paul Wrede
Download or read book Concepts in Protein Engineering and Design written by Paul Wrede and published by Walter de Gruyter GmbH & Co KG. This book was released on 2020-10-12 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: No detailed description available for "Concepts in Protein Engineering and Design".
Book Synopsis Protein Engineering For Industrial Biotechnology by : Lilia Alberghina
Download or read book Protein Engineering For Industrial Biotechnology written by Lilia Alberghina and published by CRC Press. This book was released on 2003-09-02 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: Protein engineering has proved to be one of the more fruitful technological approaches in biotechnology, being both very powerful and able to generate valuable intellectual property. This book aims to present examples in which the application of protein engineering has successfully solved problems arising in industrial biotechnology. There is a section on its use to enhance purification of recombinant proteins. The use of protein engineering to modify the activity or the stability of industrial enzymes from lipases to proteases, from carboxypeptidases to glucanases and glucosidases, and from pectin modifying enzymes to enzymes able to degrade recalcitrant compounds is extensively covered. It is shown how areas as diverse as agrofood technology, fine chemistry, detergents, bioremediation and biosensors receive significant contributions from protein and solvent engineering. The application of protein engineering to health care is also covered, from the development of new vaccines to new potential therapeutic proteins. A specific notation is given to protein engineering in the development of target molecules for drug discovery. International in scope, the many contributions are drawn from academia and industry. The text should be of interest to students and researchers in industrial biotechnology as well as to everybody interested in basic research in protein structure, molecular genetics, bio-organic chemistry, biochemistry, agrobiotechnology, pharmaceutical sciences and medicine.
Download or read book Protein Design written by Raphael Guerois and published by Humana. This book was released on 2006-06-01 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Protein Design: Methods and Applications presents the most up-to-date protein design and engineering strategies so that readers can undertake their own projects with a maximum chance of success. The authors present integrated computational approaches that require various degrees of computational complexity, and the major accomplishments that have been achieved in the design and structural characterization of helical peptides and proteins.
Book Synopsis Protein Engineering by : Mallorie N. Sheehan
Download or read book Protein Engineering written by Mallorie N. Sheehan and published by . This book was released on 2013 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Protein Engineering by : Jeffrey L. Cleland
Download or read book Protein Engineering written by Jeffrey L. Cleland and published by Wiley-Liss. This book was released on 1996-02-07 with total page 558 pages. Available in PDF, EPUB and Kindle. Book excerpt: PROTEIN ENGINEERING Principles and Practice Edited by JEFFREY L. CLELAND CHARLES S. CRAIK Proteins are involved in every aspect of life-structure, motion, catalysis, recognition and regulation. Protein Engineering: Principles and Practice provides a basic framework for understanding both proteins and protein engineering. This comprehensive book covers general, yet essential knowledge required for successful protein engineering, including everything from the fundamentals to modifying existing proteins and developing new proteins. The book begins by introducing the main concepts of protein engineering, including: understanding protein conformation, comprehending the relationship between protein composition and structure, and potential methods for predicting a protein's conformation. Other major subjects addressed are: * Using different host cell expression systems to produce specific proteins * Protein folding * Structure and function of proteins in relation to drug design * Construction of synthetic metal binding sites in proteins * Manufacture of tissue plasminogen activator * Generation of therapeutic antibodies This broad range of topics provides a solid foundation in protein engineering and supplies readers with knowledge essential to the design and production of proteins. Of primary interest to protein scientists-both students and researchers, in academia as well as industry-Protein Engineering is also extremely useful to chemical engineers, protein chemists, biochemists, and pharmaceutical chemists.
