Protein Biosynthesis In Eukaryotes

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Protein Biosynthesis in Eukaryotes

Author : R. Perez-Bercoff
Publisher : Springer
ISBN 13 : 9781468441260
Total Pages : 501 pages
Book Rating : 4.4/5 (412 download)

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Book Synopsis Protein Biosynthesis in Eukaryotes by : R. Perez-Bercoff

Download or read book Protein Biosynthesis in Eukaryotes written by R. Perez-Bercoff and published by Springer. This book was released on 2012-07-01 with total page 501 pages. Available in PDF, EPUB and Kindle. Book excerpt: vi The word ppotein, coined one and a half century ago from the 1TpOTE:toa ("proteios" = of primary importance), underlines the "primary importance" ascribed to proteins from the time they were described as biochemical entities. But the unmatched compl~xity of the process involved in their biosynthesis was (understandably) overlooked. Indeed, protein biosynthesis was supposed to be nothing more than the reverse of protein degradation, and the same enzymes known to split a protein into its constituent amino acids were thought to be able, under adequate conditions, to reconstitute the peptide bond. This oversimplified view persisted for more than 50 years: It was just in 1940 that Borsook and Dubnoff examined the thermodynamical aspects of the process, and concluded that protein synthesis could not be the reverse of protein degradation, such an "uphill task being thermody namically impossible ••• • " The next quarter of a century witnessed the unravelling of the basic mechanisms of protein biosynthesis, a predictable aftermath of the Copernican revolution in biology which followed such dramatic de velopments as the discovery of the nature of the genetic material, the double helical structure· of DNA, and the determination of the ge netic code. Our present understanding of the sophisticated mechan isms of regulation and control is a relatively novel acquisition, and recent studies have shed some light into the structure and organi zation of the eukaryotic gene.

Molecular Biology of the Cell

Author :
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

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Book Synopsis Molecular Biology of the Cell by :

Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Protein Synthesis and Ribosome Structure

Author : Knud H. Nierhaus
Publisher : John Wiley & Sons
ISBN 13 : 9783527306381
Total Pages : 608 pages
Book Rating : 4.3/5 (63 download)

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Book Synopsis Protein Synthesis and Ribosome Structure by : Knud H. Nierhaus

Download or read book Protein Synthesis and Ribosome Structure written by Knud H. Nierhaus and published by John Wiley & Sons. This book was released on 2004-10-15 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt: Knud Nierhaus, who has studied the ribosome for more than 30 years, has assembled here the combined efforts of several scientific disciplines into a uniform picture of the largest enzyme complex found in living cells, finally resolving many decades-old questions in molecular biology. In so doing he considers virtually all aspects of ribosome structure and function -- from the molecular mechanism of different ribosomal ribozyme activities to their selective inhibition by antibiotics, from assembly of the core particle to the regulation of ribosome component synthesis. The result is a premier resource for anyone with an interest in ribosomal protein synthesis, whether in the context of molecular biology, biotechnology, pharmacology or molecular medicine.

Human Biochemistry

Author : Gerald Litwack
Publisher : Academic Press
ISBN 13 : 032391053X
Total Pages : 883 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Human Biochemistry by : Gerald Litwack

Download or read book Human Biochemistry written by Gerald Litwack and published by Academic Press. This book was released on 2021-11-28 with total page 883 pages. Available in PDF, EPUB and Kindle. Book excerpt: **Selected for Doody's Core Titles® 2024 in Biochemistry** Human Biochemistry, Second Edition provides a comprehensive, pragmatic introduction to biochemistry as it relates to human development and disease. Here, Gerald Litwack, award-wining researcher and longtime teacher, discusses the biochemical aspects of organ systems and tissue, cells, proteins, enzymes, insulins and sugars, lipids, nucleic acids, amino acids, polypeptides, steroids, and vitamins and nutrition, among other topics. Fully updated to address recent advances, the new edition features fresh discussions on hypothalamic releasing hormones, DNA editing with CRISPR, new functions of cellular prions, plant-based diet and nutrition, and much more. Grounded in problem-driven learning, this new edition features clinical case studies, applications, chapter summaries, and review-based questions that translate basic biochemistry into clinical practice, thus empowering active clinicians, students and researchers. - Presents an update on a past edition winner of the 2018 Most Promising New Textbook (College) Award (Texty) from the Textbook and Academic Authors Association and the PROSE Award of the Association of American Publishers - Provides a fully updated resource on current research in human and medical biochemistry - Includes clinical case studies, applications, chapter summaries and review-based questions - Adopts a practice-based approach, reflecting the needs of both researchers and clinically oriented readers

Brain Neurotrauma

Author : Firas H. Kobeissy
Publisher : CRC Press
ISBN 13 : 1466565993
Total Pages : 718 pages
Book Rating : 4.4/5 (665 download)

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Book Synopsis Brain Neurotrauma by : Firas H. Kobeissy

Download or read book Brain Neurotrauma written by Firas H. Kobeissy and published by CRC Press. This book was released on 2015-02-25 with total page 718 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the contribution from more than one hundred CNS neurotrauma experts, this book provides a comprehensive and up-to-date account on the latest developments in the area of neurotrauma including biomarker studies, experimental models, diagnostic methods, and neurotherapeutic intervention strategies in brain injury research. It discusses neurotrauma mechanisms, biomarker discovery, and neurocognitive and neurobehavioral deficits. Also included are medical interventions and recent neurotherapeutics used in the area of brain injury that have been translated to the area of rehabilitation research. In addition, a section is devoted to models of milder CNS injury, including sports injuries.

Biology for AP ® Courses

Author : Julianne Zedalis
Publisher :
ISBN 13 : 9781947172401
Total Pages : 1923 pages
Book Rating : 4.1/5 (724 download)

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Book Synopsis Biology for AP ® Courses by : Julianne Zedalis

Download or read book Biology for AP ® Courses written by Julianne Zedalis and published by . This book was released on 2017-10-16 with total page 1923 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biology for AP® courses covers the scope and sequence requirements of a typical two-semester Advanced Placement® biology course. The text provides comprehensive coverage of foundational research and core biology concepts through an evolutionary lens. Biology for AP® Courses was designed to meet and exceed the requirements of the College Board’s AP® Biology framework while allowing significant flexibility for instructors. Each section of the book includes an introduction based on the AP® curriculum and includes rich features that engage students in scientific practice and AP® test preparation; it also highlights careers and research opportunities in biological sciences.

The Eukaryotic Ribosome

Author : Heinz Bielka
Publisher : Walter de Gruyter GmbH & Co KG
ISBN 13 : 3112729757
Total Pages : 340 pages
Book Rating : 4.1/5 (127 download)

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Book Synopsis The Eukaryotic Ribosome by : Heinz Bielka

Download or read book The Eukaryotic Ribosome written by Heinz Bielka and published by Walter de Gruyter GmbH & Co KG. This book was released on 1982-12-31 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: No detailed description available for "The Eukaryotic Ribosome".

Regulatory Nascent Polypeptides

Author : Koreaki Ito
Publisher : Springer
ISBN 13 : 4431550526
Total Pages : 313 pages
Book Rating : 4.4/5 (315 download)

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Book Synopsis Regulatory Nascent Polypeptides by : Koreaki Ito

Download or read book Regulatory Nascent Polypeptides written by Koreaki Ito and published by Springer. This book was released on 2014-08-19 with total page 313 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights a new paradigm of translation control by regulatory nascent polypeptides, which is integrated into cellular regulatory systems. Translation lies in the hub of the central dogma of biology, in which the genetic information in the forms of 4-letter sentences is translated into 20-letter sentences: sequences of amino acids that constitute proteins, the functional molecules of life. The process involves a huge number of chemical reactions as well as physical movements of the ribosome along a messenger RNA and takes, on average, tens of seconds in prokaryotes and a few minutes in eukaryotes. Detailed knowledge about the progression of translation, called "elongation", only recently started to accumulate. Newly synthesized and growing polypeptides, called nascent polypeptides, can interact with the intra-ribosomal conduit, called the ribosomal exit tunnel, when they have some specific amino acid sequences, called "an arrest sequence". Such interaction leads to a halt in the elongation reaction. Resulting stalling of the ribosome on messenger RNA can affect the secondary structure and/or localization of the message in the cell, consequently leading to biological outputs such as elevation or reduction of a gene product. This book provides a first collection of knowledge focused on regulatory nascent polypeptides, which have been studied recently using diverse organisms including bacteria, plants, and animals. Readers will be impressed by a new paradigm showing that proteins can function even during the course of their biosynthesis and that the ribosome, the "factory" of protein production, interacts with and inspects its products to adjust the speed of completion of each product. Moreover, regulatory nascent polypeptides can sense or monitor physiological states of the cell and modulate its ability to arrest translation. Living organisms use such intricate control mechanisms of translational speed to regulate gene expression. This book will be a useful addition for established scientists while inspiring students and young scientists to gain deeper insights into the processes of expression of genetic information.

Antimicrobial Chemotherapy

Author : Roger Finch
Publisher : OUP Oxford
ISBN 13 : 0191628654
Total Pages : 409 pages
Book Rating : 4.1/5 (916 download)

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Book Synopsis Antimicrobial Chemotherapy by : Roger Finch

Download or read book Antimicrobial Chemotherapy written by Roger Finch and published by OUP Oxford. This book was released on 2012-01-05 with total page 409 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antimicrobial agents are essential for the treatment of life-threatening infections and for managing the burden of minor infections in the community. In addition, they play a key role in organ and bone marrow transplantation, cancer chemotherapy, artificial joint and heart valve surgery. Unlike other classes of medicines, they are vulnerable to resistance from mutations in target microorganisms, and their adverse effects may extend to other patients (increased risk of cross-infection). As a consequence, there is a constant requirement for new agents, as well as practices that ensure the continued effective prescribing of licensed agents. Public awareness and concerns about drug resistant organisms has led to widespread publicity and political action in the UK, Europe and worldwide. The control of drug resistance and the implementation of good prescribing practice are now legal requirements in the UK as a result of the UK Health Act (2008). These fundamental changes underscore the need for a thorough understanding of the advantages and risks associated with specific antibiotic choices. This sixth edition of Antimicrobial Chemotherapy continues to be a valuable resource for undergraduates and graduates requiring a thorough grounding in the scientific basis and clinical application of these drugs. This new edition is updated to include the most recently licensed agents, notably in the treatment of viral infections including HIV/AIDS, and contains new guidance on prescribing practice and infection control practices that limit the development and spread of resistant organisms.

Systems Biology of Cancer

Author : Sam Thiagalingam
Publisher : Cambridge University Press
ISBN 13 : 0521493390
Total Pages : 597 pages
Book Rating : 4.5/5 (214 download)

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Book Synopsis Systems Biology of Cancer by : Sam Thiagalingam

Download or read book Systems Biology of Cancer written by Sam Thiagalingam and published by Cambridge University Press. This book was released on 2015-04-09 with total page 597 pages. Available in PDF, EPUB and Kindle. Book excerpt: An overview of the current systems biology-based knowledge and the experimental approaches for deciphering the biological basis of cancer.

Biomembranes

Author : Lionel A. Manson
Publisher : Springer
ISBN 13 : 9780306398025
Total Pages : 304 pages
Book Rating : 4.3/5 (98 download)

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Book Synopsis Biomembranes by : Lionel A. Manson

Download or read book Biomembranes written by Lionel A. Manson and published by Springer. This book was released on 1971-01-10 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains the contributions to a symposium held at Gatlinburg, Tennessee, under the auspices of the Oak Ridge National Laboratory, in April, 1971. In the past, these proceedings had appeared as a supplement to the Journal of Cellular Physiology. Due to the nature of the subject ma terial and the relevance of the topic of the symposium to the readers of BIOMEMBRANES, it was agreed by the organizers of the symposium to publish the contributions of the partici pants as a separate volume in BIOMEMBRANES. It had been originally envisaged that, from time to time, the proceedings of a conference whose subject matter was directly related to the scope of this series would be included. The proceedings are being published exactly as they have been submitted to the Editor without the usual editorial re V1S10n. This is being done to increase the speed of publica tion. For the same rOeason, no indices have been provided since the time needed to prepare an adequate subject index would have unnecessarily delayed publication. Included in the proceedings are short reports of a number of workshops that were held during the conference. The editor has received excellent cooperation from both the organizers of the conference and the several contributors to this volume. If the experiment is a success, it is thanks to their promptness.

Cellular Mechanics and Biophysics

Author : Claudia Tanja Mierke
Publisher : Springer Nature
ISBN 13 : 3030585328
Total Pages : 919 pages
Book Rating : 4.0/5 (35 download)

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Book Synopsis Cellular Mechanics and Biophysics by : Claudia Tanja Mierke

Download or read book Cellular Mechanics and Biophysics written by Claudia Tanja Mierke and published by Springer Nature. This book was released on 2020-10-30 with total page 919 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on the mechanical properties of cells, discussing the basic concepts and processes in the fields of immunology, biology, and biochemistry. It introduces and explains state-of-the-art biophysical methods and examines the role of mechanical properties in the cell/protein interaction with the connective tissue microenvironment. The book presents a unique perspective on cellular mechanics and biophysics by combining the mechanical, biological, physical, biochemical, medical, and immunological views, highlighting the importance of the mechanical properties of cells and biophysical measurement methods. The book guides readers through the complex and growing field of cellular mechanics and biophysics, connecting and discussing research findings from different fields such as biology, cell biology, immunology, physics, and medicine. Featuring suggestions for further reading throughout and addressing a wide selection of biophysical topics, this book is an indispensable guide for graduate and advanced undergraduate students in the fields of cellular mechanics and biophysics.

Translation In Eukaryotes

Author : Hans Trachsel
Publisher : CRC Press
ISBN 13 : 9780849388163
Total Pages : 438 pages
Book Rating : 4.3/5 (881 download)

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Book Synopsis Translation In Eukaryotes by : Hans Trachsel

Download or read book Translation In Eukaryotes written by Hans Trachsel and published by CRC Press. This book was released on 1991-07-24 with total page 438 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents an up-to-date review of the mechanisms and regulation of translation in eukaryotes. Topics covered include the basic biochemical reactions of translation initiation, elongation and termination, and the regulation of these reactions under different physiological conditions and in virus-infected cells. The book belongs on the shelf of everyone interested in translation in eukaryotes, including students and researchers requiring comprehensive overviews of most aspects of translation and instructors who want to cover these topics at an advanced level.

Ribosomes Structure, Function, and Dynamics

Author : Marina V. Rodnina
Publisher : Springer Science & Business Media
ISBN 13 : 3709102154
Total Pages : 428 pages
Book Rating : 4.7/5 (91 download)

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Book Synopsis Ribosomes Structure, Function, and Dynamics by : Marina V. Rodnina

Download or read book Ribosomes Structure, Function, and Dynamics written by Marina V. Rodnina and published by Springer Science & Business Media. This book was released on 2011-12-10 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ribosome is a macromolecular machine that synthesizes proteins with a high degree of speed and accuracy. Our present understanding of its structure, function and dynamics is the result of six decades of research. This book collects over 40 articles based on the talks presented at the 2010 Ribosome Meeting, held in Orvieto, Italy, covering all facets of the structure and function of the ribosome. New high-resolution crystal structures of functional ribosome complexes and cryo-EM structures of translating ribosomes are presented, while partial reactions of translation are examined in structural and mechanistic detail, featuring translocation as a most dynamic process. Mechanisms of initiation, both in bacterial and eukaryotic systems, translation termination, and novel details of the functions of the respective factors are described. Structure and interactions of the nascent peptide within, and emerging from, the ribosomal peptide exit tunnel are addressed in several articles. Structural and single-molecule studies reveal a picture of the ribosome exhibiting the energy landscape of a processive Brownian machine. The collection provides up-to-date reviews which will serve as a source of essential information for years to come.

Cell Biology by the Numbers

Author : Ron Milo
Publisher : Garland Science
ISBN 13 : 1317230698
Total Pages : 400 pages
Book Rating : 4.3/5 (172 download)

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Book Synopsis Cell Biology by the Numbers by : Ron Milo

Download or read book Cell Biology by the Numbers written by Ron Milo and published by Garland Science. This book was released on 2015-12-07 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Top 25 CHOICE 2016 Title, and recipient of the CHOICE Outstanding Academic Title (OAT) Award. How much energy is released in ATP hydrolysis? How many mRNAs are in a cell? How genetically similar are two random people? What is faster, transcription or translation?Cell Biology by the Numbers explores these questions and dozens of others provid

Mitochondria and Anaerobic Energy Metabolism in Eukaryotes

Author : William F. Martin
Publisher : Walter de Gruyter GmbH & Co KG
ISBN 13 : 3110612410
Total Pages : 269 pages
Book Rating : 4.1/5 (16 download)

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Book Synopsis Mitochondria and Anaerobic Energy Metabolism in Eukaryotes by : William F. Martin

Download or read book Mitochondria and Anaerobic Energy Metabolism in Eukaryotes written by William F. Martin and published by Walter de Gruyter GmbH & Co KG. This book was released on 2020-12-07 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mitochondria are sometimes called the powerhouses of eukaryotic cells, because mitochondria are the site of ATP synthesis in the cell. ATP is the universal energy currency, it provides the power that runs all other life processes. Humans need oxygen to survive because of ATP synthesis in mitochondria. The sugars from our diet are converted to carbon dioxide in mitochondria in a process that requires oxygen. Just like a fire needs oxygen to burn, our mitochondria need oxygen to make ATP. From textbooks and popular literature one can easily get the impression that all mitochondria require oxygen. But that is not the case. There are many groups of organismsm known that make ATP in mitochondria without the help of oxygen. They have preserved biochemical relicts from the early evolution of eukaryotic cells, which took place during times in Earth history when there was hardly any oxygen avaiable, certainly not enough to breathe. How the anaerobic forms of mitochondria work, in which organisms they occur, and how the eukaryotic anaerobes that possess them fit into the larger picture of rising atmospheric oxygen during Earth history are the topic of this book.

Comprehensive and Molecular Phytopathology

Author : Yuri Dyakov
Publisher : Elsevier
ISBN 13 : 0080469337
Total Pages : 497 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Comprehensive and Molecular Phytopathology by : Yuri Dyakov

Download or read book Comprehensive and Molecular Phytopathology written by Yuri Dyakov and published by Elsevier. This book was released on 2007-01-09 with total page 497 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers a collection of information on successive steps of molecular 'dialogue' between plants and pathogens. It additionally presents data that reflects intrinsic logic of plant-parasite interactions. New findings discussed include: host and non-host resistance, specific and nonspecific elicitors, elicitors and suppressors, and plant and animal immunity. This book enables the reader to understand how to promote or prevent disease development, and allows them to systematize their own ideas of plant-pathogen interactions.* Offers a more extensive scope of the problem as compared to other books in the market* Presents data to allow consideration of host-parasite relationships in dynamics and reveals interrelations between pathogenicity and resistance factors* Discusses beneficial plant-microbe interactions and practical aspects of molecular investigations of plant-parasite relationships* Compares historical study of common and specific features of plant immunity with animal immunity