Protein Arrays

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Protein Arrays

Author : Eric Fung
Publisher : Springer Science & Business Media
ISBN 13 : 1592597599
Total Pages : 279 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Protein Arrays by : Eric Fung

Download or read book Protein Arrays written by Eric Fung and published by Springer Science & Business Media. This book was released on 2008-02-03 with total page 279 pages. Available in PDF, EPUB and Kindle. Book excerpt: Protein Arrays: Methods and Protocols is an introduction to protein array technology and its application to the multiplexed detection of proteins. Although protein array technology has some roots in gene array technology, it can only be described as a distant relative. Unlike DNA, with its established rules of base pairing, and therefore predictable biochemical behavior, proteins are rich with diversity. Proteins can be large or small, compact or extended, basic or acidic, hydrophobic or hydrophilic, and so on. Just as importantly, their behavior is determined by the environment in which they reside, and so the composition of the buffer in which experiments are performed has a dramatic impact on the outcome of the experiment. Thus, if the goal is to simultaneously measure the expression of a large number of proteins, these variables must be addressed. Not to be deterred, scientists have created a variety of solutions to successfully detect and ch- acterize multiple proteins simultaneously. It is the intent of this volume to introduce to the reader a set of technological solutions to the diversity problem as well as to provide the reader with some examples of practical applications of these technologies.

Protein Microarray Technology

Author : Dev Kambhampati
Publisher : Wiley-Blackwell
ISBN 13 :
Total Pages : 284 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Protein Microarray Technology by : Dev Kambhampati

Download or read book Protein Microarray Technology written by Dev Kambhampati and published by Wiley-Blackwell. This book was released on 2004-03 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: Protein microarrays soon will become one of the major tools for realizing the goals of drug discovery research in the post-genome era. The book is aimed at life science researchers and scientists working in drug and pharma industry.

Reverse Phase Protein Arrays

Author : Tesshi Yamada
Publisher : Springer Nature
ISBN 13 : 9813297557
Total Pages : 264 pages
Book Rating : 4.8/5 (132 download)

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Book Synopsis Reverse Phase Protein Arrays by : Tesshi Yamada

Download or read book Reverse Phase Protein Arrays written by Tesshi Yamada and published by Springer Nature. This book was released on 2019-12-09 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides practical guidance on all aspects of reverse phase protein array (RPPA) technology, which permits the quantification of protein levels in cell or tissue lysates. In addition, the latest results are presented from laboratories across the world where experts are successfully running the challenging RPPA data platform. After an introductory chapter by the inventor of the RPPA technique, the demanding task of lysate preparation is explained. Subsequent chapters review printing platforms and analytical platforms and discuss antibody screening in detail. The role of RPPA data in integrative analyses is thoroughly examined, and the various applications of RPPA, for example to identify molecular targeting drugs or evaluate cancer drug efficacy, are discussed with reference to the latest knowledge. It is hoped that the book will foster the implementation of RPPA by documenting the practical details of the technology and by revealing its great potential. It will be of high value for researchers who plan to build an RPPA platform in their institute and for researchers, clinicians, and companies who use RPPA through collaboration with an existing RPPA facility.

Protein Arrays, Biochips and Proteomics

Author : Joanna S. Albala
Publisher : CRC Press
ISBN 13 : 9780203911129
Total Pages : 444 pages
Book Rating : 4.9/5 (111 download)

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Book Synopsis Protein Arrays, Biochips and Proteomics by : Joanna S. Albala

Download or read book Protein Arrays, Biochips and Proteomics written by Joanna S. Albala and published by CRC Press. This book was released on 2003-08-20 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: From disease marker identification to accelerated drug development, Protein Arrays, Biochips, and Proteomics offers a detailed overview of current and emerging trends in the field of array-based proteomics. This reference focuses on innovations in protein microarrays and biochips, mass spectrometry, high-throughput protein expression, protein-prote

Protein Microarrays for Disease Analysis

Author : Rodrigo Barderas
Publisher : Humana
ISBN 13 : 9781071615614
Total Pages : 282 pages
Book Rating : 4.6/5 (156 download)

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Book Synopsis Protein Microarrays for Disease Analysis by : Rodrigo Barderas

Download or read book Protein Microarrays for Disease Analysis written by Rodrigo Barderas and published by Humana. This book was released on 2021-07-11 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume focuses on protein analysis, and covers a wide array of uses of protein microarray for disease analysis. The chapters in this book discuss different stages of protein microarrays from their construction to their use, including different types of protein microarrays such as recombinant proteins, antibody, phage, and NAPPA protein microarrays, in planar format or in solution via beads arrays. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and cutting-edge, Protein Microarrays for Disease Analysis: Methods and Protocols is a valuable resource for graduate and post-doctoral fellows interested in protein microarrays, as well as senior researchers interested in gaining more insight into this developing field.

Exploration and Analysis of DNA Microarray and Protein Array Data

Author : Dhammika Amaratunga
Publisher : John Wiley & Sons
ISBN 13 : 0470317965
Total Pages : 270 pages
Book Rating : 4.4/5 (73 download)

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Book Synopsis Exploration and Analysis of DNA Microarray and Protein Array Data by : Dhammika Amaratunga

Download or read book Exploration and Analysis of DNA Microarray and Protein Array Data written by Dhammika Amaratunga and published by John Wiley & Sons. This book was released on 2009-09-25 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: A cutting-edge guide to the analysis of DNA microarray data Genomics is one of the major scientific revolutions of this century, and the use of microarrays to rapidly analyze numerous DNA samples has enabled scientists to make sense of mountains of genomic data through statistical analysis. Today, microarrays are being used in biomedical research to study such vital areas as a drug’s therapeutic value–or toxicity–and cancer-spreading patterns of gene activity. Exploration and Analysis of DNA Microarray and Protein Array Data answers the need for a comprehensive, cutting-edge overview of this important and emerging field. The authors, seasoned researchers with extensive experience in both industry and academia, effectively outline all phases of this revolutionary analytical technique, from the preprocessing to the analysis stage. Highlights of the text include: A review of basic molecular biology, followed by an introduction to microarrays and their preparation Chapters on processing scanned images and preprocessing microarray data Methods for identifying differentially expressed genes in comparative microarray experiments Discussions of gene and sample clustering and class prediction Extension of analysis methods to protein array data Numerous exercises for self-study as well as data sets and a useful collection of computational tools on the authors’ Web site make this important text a valuable resource for both students and professionals in the field.

Supramolecular Structure and Function 7

Author : Greta Pifat-Mrzljak
Publisher : Springer Science & Business Media
ISBN 13 : 1461513634
Total Pages : 238 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Supramolecular Structure and Function 7 by : Greta Pifat-Mrzljak

Download or read book Supramolecular Structure and Function 7 written by Greta Pifat-Mrzljak and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume represents a collection of lectures delivered by outstanding specialists in the fields of biophysics and of related scientific disciplines th during the 7 International Summer School on Biophysics held in Rovinj, Croatia from 14 to 25 September 2000 under the title "Super molecular Structure and Function ". This scientific-educational event was organized by the Ruder Boskovic Institute ofZagreb, Croatia with substantial material and intellectual support of a number of national and international institutions including the Croatian Biophysical Society (CBS), the International Union of Pure and Applied Biophysics (IUPAB), the International Centre for Genetic Engineering and Biotechnology (ICGEB) and the UNESCO Venice Office - Regional Office for Science and Technology for Europe (UVO-ROSTE). The seventh edition of the series of International Summer Schools on Biophysics, which was started in 198I, attracted more than 120 young researchers and post-graduate students coming from 27 countries of Europe, Asia, Africa and Latin America. Twenty-five outstanding experts in pure and applied biophysics presented the most advanced knowledge ofthis very interdisciplinary area of science during their lectures and round tables. It was commonly acknowledge that the Summer School achieved great success and fully reached its objectives. The success of the Rovinj Summer School was also due to the constantly growing attention being paid by scientific communities to younger generations of scientists, thanks also to the major outcomes of the World Conference on Science "Science for the Twenty-first Century: A New Commitment" held by UNESCO and ICSU in Budapest, Hungary in June 1999.

Microarray Technology in Practice

Author : Steve Russell
Publisher : Academic Press
ISBN 13 : 0080919766
Total Pages : 460 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Microarray Technology in Practice by : Steve Russell

Download or read book Microarray Technology in Practice written by Steve Russell and published by Academic Press. This book was released on 2008-11-21 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using chips composed of thousands of spots, each with the capability of holding DNA molecules corresponding to a given gene, DNA microarray technology has enabled researchers to measure simultaneously gene expression across the genome. As with other large-scale genomics approaches, microarray technologies are broadly applicable across disciplines of life and biomedical sciences, but remain daunting to many researchers. This guide is designed to demystify the technology and inform more biologists about this critically important experimental technique. - Cohesive overview of the technology and available platforms, followed by detailed discussion of experimental design and analysis of microarray experiments - Up-to-date description of normalization methods and current methods for sample amplification and labeling - Deep focus on oligonucleotide design, printing, labeling and hybridization, data acquisition, normalization, and meta-analysis - Additional uses of microarray technology such as ChIP (chromatin immunoprecipitation) with hybridization to DNA arrays, microarray-based comparative genomic hybridization (CGH), and cell and tissue arrays

Proteomics for Biological Discovery

Author : Timothy D. Veenstra
Publisher : John Wiley & Sons
ISBN 13 : 0470007737
Total Pages : 361 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Proteomics for Biological Discovery by : Timothy D. Veenstra

Download or read book Proteomics for Biological Discovery written by Timothy D. Veenstra and published by John Wiley & Sons. This book was released on 2006-06-12 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by recognized experts in the study of proteins, Proteomics for Biological Discovery begins by discussing the emergence of proteomics from genome sequencing projects and a summary of potential answers to be gained from proteome-level research. The tools of proteomics, from conventional to novel techniques, are then dealt with in terms of underlying concepts, limitations and future directions. An invaluable source of information, this title also provides a thorough overview of the current developments in post-translational modification studies, structural proteomics, biochemical proteomics, microfabrication, applied proteomics, and bioinformatics relevant to proteomics. Presents a comprehensive and coherent review of the major issues faced in terms of technology development, bioinformatics, strategic approaches, and applications Chapters offer a rigorous overview with summary of limitations, emerging approaches, questions, and realistic future industry and basic science applications Discusses higher level integrative aspects, including technical challenges and applications for drug discovery Accessible to the novice while providing experienced investigators essential information Proteomics for Biological Discovery is an essential resource for students, postdoctoral fellows, and researchers across all fields of biomedical research, including biochemistry, protein chemistry, molecular genetics, cell/developmental biology, and bioinformatics.

Proteomic and Metabolomic Approaches to Biomarker Discovery

Author : Haleem J. Issaq
Publisher : Academic Press
ISBN 13 : 0123947952
Total Pages : 489 pages
Book Rating : 4.1/5 (239 download)

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Book Synopsis Proteomic and Metabolomic Approaches to Biomarker Discovery by : Haleem J. Issaq

Download or read book Proteomic and Metabolomic Approaches to Biomarker Discovery written by Haleem J. Issaq and published by Academic Press. This book was released on 2013-05-20 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proteomic and Metabolomic Approaches to Biomarker Discovery demonstrates how to leverage biomarkers to improve accuracy and reduce errors in research. Disease biomarker discovery is one of the most vibrant and important areas of research today, as the identification of reliable biomarkers has an enormous impact on disease diagnosis, selection of treatment regimens, and therapeutic monitoring. Various techniques are used in the biomarker discovery process, including techniques used in proteomics, the study of the proteins that make up an organism, and metabolomics, the study of chemical fingerprints created from cellular processes. Proteomic and Metabolomic Approaches to Biomarker Discovery is the only publication that covers techniques from both proteomics and metabolomics and includes all steps involved in biomarker discovery, from study design to study execution. The book describes methods, and presents a standard operating procedure for sample selection, preparation, and storage, as well as data analysis and modeling. This new standard effectively eliminates the differing methodologies used in studies and creates a unified approach. Readers will learn the advantages and disadvantages of the various techniques discussed, as well as potential difficulties inherent to all steps in the biomarker discovery process. A vital resource for biochemists, biologists, analytical chemists, bioanalytical chemists, clinical and medical technicians, researchers in pharmaceuticals, and graduate students, Proteomic and Metabolomic Approaches to Biomarker Discovery provides the information needed to reduce clinical error in the execution of research. - Describes the use of biomarkers to reduce clinical errors in research - Includes techniques from a range of biomarker discoveries - Covers all steps involved in biomarker discovery, from study design to study execution

Cell-Free Protein Expression

Author : W. Antoni Kudlicki
Publisher : CRC Press
ISBN 13 : 1498713297
Total Pages : 243 pages
Book Rating : 4.4/5 (987 download)

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Book Synopsis Cell-Free Protein Expression by : W. Antoni Kudlicki

Download or read book Cell-Free Protein Expression written by W. Antoni Kudlicki and published by CRC Press. This book was released on 2007-11-27 with total page 243 pages. Available in PDF, EPUB and Kindle. Book excerpt: Following its inception in the 1950s, cell-free protein synthesis made a tremendous impact on the basic life sciences. The use of cell-free systems was key to understanding molecular mechanisms underlying one of the most complicated processes found in nature: protein translation. Since this time, aggressive cutting-edge research and stiff commerica

Molecular Analysis and Structure Determination of Two-dimensional and Helical Protein Arrays

Author : Sammy Joseph Farah
Publisher :
ISBN 13 :
Total Pages : 390 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Molecular Analysis and Structure Determination of Two-dimensional and Helical Protein Arrays by : Sammy Joseph Farah

Download or read book Molecular Analysis and Structure Determination of Two-dimensional and Helical Protein Arrays written by Sammy Joseph Farah and published by . This book was released on 2002 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Microarray Methods and Protocols

Author : Robert S. Matson
Publisher : CRC Press
ISBN 13 : 1420046667
Total Pages : 247 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Microarray Methods and Protocols by : Robert S. Matson

Download or read book Microarray Methods and Protocols written by Robert S. Matson and published by CRC Press. This book was released on 2009-01-20 with total page 247 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Step-by-Step Guide to Present and Future Uses of Microarray TechnologyMicroarray technology continues to evolve, taking on a variety of forms. From the spotting of cDNA and the in situ synthesis of oligonucleotide arrays now come microarrays comprising proteins, carbohydrates, drugs, tissues, and cells. With contributions from microarray experts

Microarrays

Author : Jang B. Rampal
Publisher : Springer Science & Business Media
ISBN 13 : 1588295893
Total Pages : 923 pages
Book Rating : 4.5/5 (882 download)

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Book Synopsis Microarrays by : Jang B. Rampal

Download or read book Microarrays written by Jang B. Rampal and published by Springer Science & Business Media. This book was released on 2007-07-27 with total page 923 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microarray Technology, Volumes 1 and 2, present information in designing and fabricating arrays and binding studies with biological analytes while providing the reader with a broad description of microarray technology tools and their potential applications. The first volume deals with methods and protocols for the preparation of microarrays. The second volume details applications and data analysis, which is important in analyzing the enormous data coming out of microarray experiments. Among the topics discussed in Volume 1: Synthesis Methods, are matrices in the synthesis of microarrays, array optimization processes, array-based comparative genomic hybridization, 60-mer oligonucleotide probes, bifunctional reagents NTMTA and NTPAC, and high density arrays using digital microarray synthesis platforms. Other topics include multiplex ligation-dependent probe amplification (MLPA), hybridization conditions in situ-synthesized oligo arrays, peptide arrays, high density replication tools (HDRT), protocols for the quantification of oligo hybridization, glyco-bead arrays, and an investigation into the emerging nano technology. Microarray Technology, Volumes 1 and 2, provide ample information to all levels of scientists from novice to those intimately familiar with array technology.

Medical Sciences - Volume II

Author : A. Wojtezak
Publisher : EOLSS Publications
ISBN 13 : 1848262841
Total Pages : 598 pages
Book Rating : 4.8/5 (482 download)

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Book Synopsis Medical Sciences - Volume II by : A. Wojtezak

Download or read book Medical Sciences - Volume II written by A. Wojtezak and published by EOLSS Publications. This book was released on 2009-08-10 with total page 598 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medical Sciences is a component of Encyclopedia of Biological, Physiological and Health Sciences in the global Encyclopedia of Life Support Systems (EOLSS), which is an integrated compendium of twenty one Encyclopedias. This 2-volume set contains several chapters, each of size 5000-30000 words, with perspectives, applications and extensive illustrations. It carries state-of-the-art knowledge in the fields of Medical Sciences and is aimed, by virtue of the several applications, at the following five major target audiences: University and College Students, Educators, Professional Practitioners, Research Personnel and Policy Analysts, Managers, and Decision Makers and NGOs.

Molecular Biology

Author : David P. Clark
Publisher : Elsevier
ISBN 13 : 0128132892
Total Pages : 1019 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Molecular Biology by : David P. Clark

Download or read book Molecular Biology written by David P. Clark and published by Elsevier. This book was released on 2018-11-02 with total page 1019 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Biology, Third Edition, provides a thoroughly revised, invaluable resource for college and university students in the life sciences, medicine and related fields. This esteemed text continues to meet the needs of students and professors by offering new chapters on RNA, genome defense, and epigenetics, along with expanded coverage of RNAi, CRISPR, and more ensuring topical content for a new class of students. This volume effectively introduces basic concepts that are followed by more specific applications as the text evolves.Moreover, as part of the Academic Cell line of textbooks, this book contains research passages that shine a spotlight on current experimental work reported in Cell Press articles. These articles form the basis of case studies found in the associated online study guide that is designed to tie current topics to the scientific community. - Winner of a 2020 Textbook Excellence Award (College) (Texty) from the Textbook and Academic Authors Association - Contains new chapters on non-coding RNA, genome defense, epigenetics and epigenomics - Features new and expanded coverage of RNAi, CRISPR, genome editing, giant viruses and proteomics - Provides an ancillary package with updated PowerPoint slide images

Immunoassay and Other Bioanalytical Techniques

Author : Jeanette M. van Emon
Publisher : CRC Press
ISBN 13 : 1420020692
Total Pages : 532 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Immunoassay and Other Bioanalytical Techniques by : Jeanette M. van Emon

Download or read book Immunoassay and Other Bioanalytical Techniques written by Jeanette M. van Emon and published by CRC Press. This book was released on 2016-04-19 with total page 532 pages. Available in PDF, EPUB and Kindle. Book excerpt: Taking an interdisciplinary approach that emphasizes the adaptability of immunochemical and related bioanalytical methods to a variety of matrices, Immunoassay and Other Bioanalytical Techniques describes the strength and the versatility of these methods in a wide range of environmental and biological measurement applications. With contribut