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Prostaglandins And The Kidney
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Book Synopsis Prostaglandins and the Kidney by : Michael Dunn
Download or read book Prostaglandins and the Kidney written by Michael Dunn and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: In June, 1981, we conducted a two day international symposium in Rome devoted to original scientific presentations on arachidonic acid metabolism in the kidney. Scientists from 20 countries were represented either in the general scientific program or in the poster presentation. This book does not represent the proceedings of this international gathering, but rather the edited manuscripts specifically prepared as sum maries of the scientific presentations. We feel that the timeliness and originality of the contributions as well as the need for a compilation of existing work on prosta glandins, thromboxane, and the kidney warrant this publication. The meetings would have been impossible without the generous and substantial support of the Italian government, the National Institutes of Health, United States Public Health Service, and Merck Sharp & Dohme International. Supplementary support was also received from Ciba Geigy S. p. A., Ente Fiuggi, Farmitalia Carlo Erba S. p. A., Glaxo Laboratori S. p. A., Hoechst Italia S. p. A., Leo Pharmaceutical Products, Pfizer Italiana S. p. A., Sigm? Tau S. p. A., Squibb S. p. A., The Upjohn Company, Wellcome Italia S. p. A., and Burroughs Wellcome Company. The efficient organization of the symposium was largely attributable to the superb efforts of Elisabeth Mutschlechner and Miki Scarinci of C.K. International, Rome. Linda Goldberg provided expert and invaluable editorial and secretarial assistance in the organization of this book. The book is divided into four major sections comprising: I.
Book Synopsis Prostaglandins and the Kidney by : Richard Horton
Download or read book Prostaglandins and the Kidney written by Richard Horton and published by S. Karger AG (Switzerland). This book was released on 1981 with total page 104 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Prostaglandins in Cardiovascular and Renal Functions by : A. Scriabine
Download or read book Prostaglandins in Cardiovascular and Renal Functions written by A. Scriabine and published by Springer. This book was released on 1980-10-31 with total page 530 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Renal Prostaglandins by : James B. Lee
Download or read book Renal Prostaglandins written by James B. Lee and published by . This book was released on 1977 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Prostaglandins and Kidney Function by : Ernst Oliw
Download or read book Prostaglandins and Kidney Function written by Ernst Oliw and published by . This book was released on 1979 with total page 66 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Essential Clinical Anesthesia by : Charles Vacanti
Download or read book Essential Clinical Anesthesia written by Charles Vacanti and published by Cambridge University Press. This book was released on 2011-07-11 with total page 1191 pages. Available in PDF, EPUB and Kindle. Book excerpt: The clinical practice of anesthesia has undergone many advances in the past few years, making this the perfect time for a new state-of-the-art anesthesia textbook for practitioners and trainees. The goal of this book is to provide a modern, clinically focused textbook giving rapid access to comprehensive, succinct knowledge from experts in the field. All clinical topics of relevance to anesthesiology are organized into 29 sections consisting of more than 180 chapters. The print version contains 166 chapters that cover all of the essential clinical topics, while an additional 17 chapters on subjects of interest to the more advanced practitioner can be freely accessed at www.cambridge.org/vacanti. Newer techniques such as ultrasound nerve blocks, robotic surgery and transesophageal echocardiography are included, and numerous illustrations and tables assist the reader in rapidly assimilating key information. This authoritative text is edited by distinguished Harvard Medical School faculty, with contributors from many of the leading academic anesthesiology departments in the United States and an introduction from Dr S. R. Mallampati. This book is your essential companion when preparing for board review and recertification exams and in your daily clinical practice.
Book Synopsis Clinical Nephrotoxins by : Marc E. de Broe
Download or read book Clinical Nephrotoxins written by Marc E. de Broe and published by Springer Science & Business Media. This book was released on 2007-05-08 with total page 719 pages. Available in PDF, EPUB and Kindle. Book excerpt: To you the reader, the joy of discovery begins, for We continue in our goal of providing a text which us the job is done. In this edition, we have corrected is useful, not only to the clinician, but of equal interest past deficiencies, added new topics, expanded infor- to the investigator. The selection of content has been mation regarding the pediatric age group, provided directed at topics of current interest rather than those up to date (March 2003) references, while remaining of historic contribution. We have stressed the cont- true to our concept of a multi-national author book. bution of cell biology and pathophysiology, were it We continue to believe that scientific information is an exists, believing it provides both a better understa- international commodity whose interpretation and ap- ing of toxic injury when known, and a rational dir- plication are strongly influenced by both the cultural tion for therapy and prevention. and ethnic background of the observer. The oppor- nity to share in the rich diversity of the international We are encouraged by the accumulation of rec- scientific community remains a fundamental goal of nized risk factors, which allow pre-treatment strati- this endeavor. To participate as equals leads to mu- cation of our patients’ relative risk and allow us to - tual respect and peer appreciation. The sharing of in- cus our preventative techniques on the individuals tellectual resources fostered by this effort should and most likely to gain the greatest benefit.
Book Synopsis Rheumatology and the Kidney by : Dwomoa Adu
Download or read book Rheumatology and the Kidney written by Dwomoa Adu and published by OUP Oxford. This book was released on 2012-04-05 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covering all aspects of the many rheumatologic disorders associated with renal disease, including pathogenesis, clinical features and treatment, Rheumatology and the Kidney brings together the available information in an accessible and practical way, with a particular focus on evidence-based patient management. Part of the Oxford Clinical Nephrology Series, and featuring chapters from a team of international experts, this new edition has been completely updated since publication of the first edition in 2001 and now contains more tables and figures to make the information more accessible. Completely updated since publication of the first edition in 2001, and with more illustrations, this book brings together the available information on the many rheumatologic disorders associated with renal disease in an accessible and practical way, with a particular focus on evidence-based patient management.
Book Synopsis Prostaglandins as a Factor in the Short Term Renal Response to Unilateral Nephrectomy by : Dale Ann Hartupee
Download or read book Prostaglandins as a Factor in the Short Term Renal Response to Unilateral Nephrectomy written by Dale Ann Hartupee and published by . This book was released on 1978 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Silva's Diagnostic Renal Pathology by : Xin J. Zhou
Download or read book Silva's Diagnostic Renal Pathology written by Xin J. Zhou and published by Cambridge University Press. This book was released on 2017-03-02 with total page 691 pages. Available in PDF, EPUB and Kindle. Book excerpt: An algorithmic approach to interpreting renal pathology, updated in light of recent advances in understanding and new classification schemes.
Book Synopsis Neural Control of Renal Function by : Ulla Kopp
Download or read book Neural Control of Renal Function written by Ulla Kopp and published by Morgan & Claypool Publishers. This book was released on 2011 with total page 99 pages. Available in PDF, EPUB and Kindle. Book excerpt: The kidney is innervated with efferent sympathetic nerve fibers reaching the renal vasculature, the tubules, the juxtaglomerular granular cells, and the renal pelvic wall. The renal sensory nerves are mainly found in the renal pelvic wall. Increases in efferent renal sympathetic nerve activity reduce renal blood flow and urinary sodium excretion by activation of α1-adrenoceptors and increase renin secretion rate by activation of β1-adrenoceptors. In response to normal physiological stimulation, changes in efferent renal sympathetic nerve activity contribute importantly to homeostatic regulation of sodium and water balance. The renal mechanosensory nerves are activated by stretch of the renal pelvic tissue produced by increases in renal pelvic tissue of a magnitude that may occur during increased urine flow rate. Activation of the sensory nerves elicits an inhibitory renorenal reflex response consisting of decreases in efferent renal sympathetic nerve activity leading to natriuresis. Increasing efferent sympathetic nerve activity increases afferent renal nerve activity which, in turn, decreases efferent renal sympathetic nerve activity by activation of the renorenal reflexes. Thus, activation of the afferent renal nerves buffers changes in efferent renal sympathetic nerve activity in the overall goal of maintaining sodium balance. In pathological conditions of sodium retention, impairment of the inhibitory renorenal reflexes contributes to an inappropriately increased efferent renal sympathetic nerve activity in the presence of sodium retention. In states of renal disease or injury, there is a shift from inhibitory to excitatory reflexes originating in the kidney. Studies in essential hypertensive patients have shown that renal denervation results in long-term reduction in arterial pressure, suggesting an important role for the efferent and afferent renal nerves in hypertension. Table of Contents: Part I: Efferent Renal Sympathetic Nerves / Introduction / Neuroanatomy / Neural Control of Renal Hemodynamics / Neural Control of Renal Tubular Function / Neural Control of Renin Secretion Rate / Part II: Afferent Renal Sensory Nerves / Introduction / Neuroanatomy / Renorenal Reflexes / Mechanisms Involved in the Activation of Afferent Renal Sensory Nerves / Part III: Pathophysiological States / Efferent Renal Sympathetic Nerves / Afferent Renal Sensory Nerves / Conclusions / References
Book Synopsis Oxford Textbook of Endocrinology and Diabetes by : John A.H. Wass
Download or read book Oxford Textbook of Endocrinology and Diabetes written by John A.H. Wass and published by Oxford University Press, USA. This book was released on 2011-07-28 with total page 2158 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in its second edition, the Oxford Textbook of Endocrinology and Diabetes is a fully comprehensive, evidence-based, and highly-valued reference work combining basic science with clinical guidance, and providing first rate advice on diagnosis and treatment.
Download or read book Itch written by E. Carstens and published by CRC Press. This book was released on 2014-02-25 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in itch research have elucidated differences between itch and pain but have also blurred the distinction between them. There is a long debate about how somatic sensations including touch, pain, itch, and temperature sensitivity are encoded by the nervous system. Research suggests that each sensory modality is processed along a fixed, direct-line communication system from the skin to the brain. Itch: Mechanisms and Treatment presents a timely update on all aspects of itch research and the clinical treatment of itch that accompanies many dermatological conditions including psoriasis, neuropathic itch, cutaneous t-cells lymphomas, and systemic diseases such as kidney and liver disease and cancer. Composed of contributions from distinguished researchers around the world, the book explores topics such as: Neuropathic itch Peripheral neuronal mechanism of itch The role of PAR-2 in neuroimmune communication and itch Mrgprs as itch receptors The role of interleukin-31 and oncostatin M in itch and neuroimmune communication Spinal coding of itch and pain Spinal microcircuits and the regulation of itch Examining new findings on cellular and molecular mechanisms, the book is a compendium of the most current research on itch, its prevalence in society, and the problems associated with treatment.
Book Synopsis Selective COX-2 Inhibitors by : Sir John R. Vane
Download or read book Selective COX-2 Inhibitors written by Sir John R. Vane and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 153 pages. Available in PDF, EPUB and Kindle. Book excerpt: The mainstay of therapy for rheumatoid disease is the non-steroid antiinflammatory drugs (NSAIDs), despite their inherent gastrointestinal toxicity and ability to cause renal damage in susceptible patients. The theory that the beneficial and toxic effects of NSAIDs stem from a reduction in prostanoid production through inhibition of cyclooxygenase implied that particular toxicities were inevitable with NSAIDs and would always be correlated with efficacy. However, over the years, it became apparent that at therapeutic doses, some NSAIDs had greater toxic side-effects than others, a fact not explained by the general theory. A significant clarification arose from the discovery that there are two distinct isoforms of COX, a constitutive enzyme (COX-I) responsible for the production of prostanoids necessary for platelet aggregation and protection of the gastric mucosa and kidney; and an inducible enzyme (COX-2) that is newly synthesized at sites of tissue damage and produces prostaglandins that manifest pathological effects. It became clear that different NSAIDs had greater or lesser effects on COX-I when used in therapeutic doses, explaining the variation in side-effects. ' The elucidation of the crystal structure of these different enzymes and the skills of medicinal chemists have led to the synthesis of new chemicals with a selectivity for the inducible enzyme, and thus with therapeutic efficacy without those toxic effects result ing from inhibition of the constitutive enzyme.
Book Synopsis Prostaglandin D2 Synthase by : Louis Ragolia
Download or read book Prostaglandin D2 Synthase written by Louis Ragolia and published by . This book was released on 2007-01-01 with total page 209 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nearly a decade after first learning of this remarkable protein, Prostaglandin D2 Synthase continues to amaze me with its ever-growing array of novel functions. Prostaglandin D2 Synthase- A Multitude of Biological Functions reveals several of the most recent and interesting aspects of this protein and is divided into five parts: In Part I, Ko Fujimori examines the structure and regulation of the lipocalin-type prostaglandin D2 synthase (L-PGDS) gene; Takashi Inui then explains the folding and unfolding mechanisms of the protein while an evolutionary analysis of L-PGDS is provided by Hisako Ichihara, Kei-ichi Kuma, Yoshihiro Urade, and Hiroyuki Toh; Yoshihiro Urade and Kosuke Aritake then introduce some novel properties associated with L-PGDS. In Part II, reproductive and fetal aspects of L-PGDS are provided by Zeng-Ming Yang, Murray Mitchell, Rachel J. A. Helliwell, Mhoyra Fraser, and Jeffrey A. Keelan. Vascular aspects of L-PGDS are provided in Part III by Louis Ragolia, who exposes the role of L-PGDS in insulin resistance, inflammation and atherosclerosis and introduces the concept of L-PGDS as a vital hub to the metabolic syndrome; Maria Luigia Fazia, Andrea Mezzetti, and Francesco Cipollone, examine the expression and role of L-PGDS in atherothrombosis; Yoshikazu Miwa and Toshiyuki Sasaguri, discusses its role as a vasoprotective factor; and Hideyuki Negoro examines the role of endogenous prostaglandin D2 in the pathogenesis of cardiovascular injuries. In Part IV Masako Taniike and Ikuko Mohri examine the pathophysiological role of L-PGDS in neurological disorders while Atsushi Hiraoka characterizes the various isoforms found in cerebrospinal fluid. Finally, the association to cancer is discussed in Part V by Abhijit Banerjee, who examines L-PGDS in Cancer Progression. It is my desire that this book will both expose and inspire those unfamiliar with the vast and complex actions of this extraordinary protein, and foster additional research on a protein which I believe holds great promise for therapeutic disease intervention. I would like to express my deep gratitude to all of the contributing authors for providing their individual expertise and perspective to help construct this book. I would also like to thank Dr. S. G. Pandalai and Research Signpost for the invitation and agreement to publish this compilation. Finally, I would like to thank Winthrop University Hospital s Board of Directors for their continued support and commitment to basic research.
Book Synopsis Prostaglandins by : Jerome S. Tannenbaum
Download or read book Prostaglandins written by Jerome S. Tannenbaum and published by . This book was released on 1980 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Prostaglandins and the Kidney by : Michael Dunn
Download or read book Prostaglandins and the Kidney written by Michael Dunn and published by . This book was released on 2014-01-15 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt:
