Prostaglandins And Leukotrienes In Gastrointestinal Diseases

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Prostaglandins and Leukotrienes in Gastrointestinal Diseases

Author : W. Domschke
Publisher : Springer Science & Business Media
ISBN 13 : 3642733166
Total Pages : 523 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis Prostaglandins and Leukotrienes in Gastrointestinal Diseases by : W. Domschke

Download or read book Prostaglandins and Leukotrienes in Gastrointestinal Diseases written by W. Domschke and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 523 pages. Available in PDF, EPUB and Kindle. Book excerpt: In OCtober 1986, recognized authorities from a variety of disciplines met in Lisbon, Portugal, to review recent knowledge on eicosanoids - i. e., prostaglandins, throm boxane A , and leukotrienes - and their role in gastrointestinal diseases. 2 Briefly, in the stomach endogenous as well as exogenous prostaglandins may mediate cytoprotective actions in that they stimulate gastric mucus production, bicar bonate secretion and cellular regeneration while providing adequate mucosal blood flow. In contrast, thromboxane A2 by vasoconstriction may act as an ulcerogenic substance. Diarrheal states may be associated with prostaglandins of types E and F as they are capable to enhance intestinal water and electrolyte secretions. In chronic in flammatory bowel disease, mucosal synthesis of leukotrienes was found to be increased more markedly than that of prostaglandins suggesting that leukotrienes may have a major part in the pathogenesis of that disease. In this volume, which is an elaborated collection of the papers given on occasion of the above-mentioned symposium, the facts and problems associated with prostanoid substances are dealt with in four sections on 1. biochemistry, biology and pharmacology of eicosanoids, 2. physiologic and pathophysiologic aspects, 3. established therapeutic implications, and 4. treatment perspectives. We believe that the publication of these contributions by leading workers in the given fields provides a comprehensive and up-to-date appraisal of the role of eicosanoids in gastrointestinal diseases, and it is hoped that this volume will be of value to both basic scientists and practicing clinicians.

Prostaglandins and Leukotrienes in Gastrointestinal Diseases

Author : Wolfram Domschke
Publisher : Springer Verlag
ISBN 13 : 9780387187440
Total Pages : 332 pages
Book Rating : 4.1/5 (874 download)

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Book Synopsis Prostaglandins and Leukotrienes in Gastrointestinal Diseases by : Wolfram Domschke

Download or read book Prostaglandins and Leukotrienes in Gastrointestinal Diseases written by Wolfram Domschke and published by Springer Verlag. This book was released on 1988 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Advances in Prostaglandin, Leukotriene, and other Bioactive Lipid Research

Author : Zeliha Yazici
Publisher : Springer Science & Business Media
ISBN 13 : 1441991948
Total Pages : 240 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Advances in Prostaglandin, Leukotriene, and other Bioactive Lipid Research by : Zeliha Yazici

Download or read book Advances in Prostaglandin, Leukotriene, and other Bioactive Lipid Research written by Zeliha Yazici and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume, the Proceedings of the 12th International Conference on Advances in Prostaglandin, Leukotriene and Other Bioactive Lipid Research: Basic Science and Clinical Applications, held August 25-29, 2002, in Istanbul, Turkey, discusses advances in bioactive lipid research with special attention to cancer, cardiovascular diseases, gastrointestinal diseases and respiratory diseases. Specific topics covered include the role of leukotrienes and lipoxins in inflammation, the cytochrome P450 pathway, the genetics and genomics of bioactive lipids, lipid peroxidation, apoptosis, angiogenesis, isoprostanes, receptors and inhibitors, cyclooxygenase and lipoxygenase pathways and inhibitors, prostaglandin synthases and receptor signaling, phospholipases and inhibitors.

Eicosanoids and the Gastrointestinal Tract

Author : K. Hillier
Publisher :
ISBN 13 : 9789400912823
Total Pages : 232 pages
Book Rating : 4.9/5 (128 download)

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Book Synopsis Eicosanoids and the Gastrointestinal Tract by : K. Hillier

Download or read book Eicosanoids and the Gastrointestinal Tract written by K. Hillier and published by . This book was released on 1988-04-30 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Motility of the Digestive Tract

Author : Martin Wienbeck
Publisher : Raven Press (ID)
ISBN 13 :
Total Pages : 648 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Motility of the Digestive Tract by : Martin Wienbeck

Download or read book Motility of the Digestive Tract written by Martin Wienbeck and published by Raven Press (ID). This book was released on 1982 with total page 648 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Endogenous Mediators of Gastrointestinal Damage

Author : John L. Wallace
Publisher : CRC Press
ISBN 13 : 084934574X
Total Pages : 236 pages
Book Rating : 4.8/5 (493 download)

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Book Synopsis Endogenous Mediators of Gastrointestinal Damage by : John L. Wallace

Download or read book Endogenous Mediators of Gastrointestinal Damage written by John L. Wallace and published by CRC Press. This book was released on 1989-09-30 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text helps the reader determine whether or not the gastrointestinal mucosa ulcerates can be viewed as a balance between aggressive factors present in the lumen and the mucosal defence system. Several of these aggressive factors, such as acid, bile and pepsin, are endogenous substances. Similarly, several endogenous substances exert control over mucosal blood flow and secretion and thus are important mediators of mucosal defence. In this volume, experts in this field have contributed chapters on some of the most important of these endogenous mediators, including histamine, prostaglandins, leukotrienes and platelet-activating factor. The potential contribution of these mediators to gastrointestinal disease has been assessed. Also discussed is the role these mediators play in gastrointestinal side effects of drugs (i.e. non-steroidal anti-inflammatory drugs). Also covered are the mechanisms of action of endogenous mediators relative to the the drugs used clinically for the treatment of maladies of the digestive system. This volume will be of interest to the basic scientist, the clinical investigator and to students of pathophysiology and medicine.

Eicosanoids in Inflammatory Conditions of the Lung, Skin and Joints

Author : M.K. Church
Publisher : Springer
ISBN 13 : 9789401070706
Total Pages : 240 pages
Book Rating : 4.0/5 (77 download)

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Book Synopsis Eicosanoids in Inflammatory Conditions of the Lung, Skin and Joints by : M.K. Church

Download or read book Eicosanoids in Inflammatory Conditions of the Lung, Skin and Joints written by M.K. Church and published by Springer. This book was released on 2011-10-12 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: The original series, Advances in Prostaglandin Research, edited by Sultan M. M. Karim, was published by MTP Press in three volumes in 1975 and 1976. A glance at those books illustrates the progress that has been made since then. The thromboxanes were mentioned twice (first publication 1975) and prostacyclin not once (first publication 1976); leukotrienes were only on the horizon. The amazing generation of research data in the last 10-15 years has given new, broad insights into many areas, including asthma, inflammation, renal, cardiovascular and gastrointestinal diseases and in reproduction, and has led in some instances to real clinical benefit. This series, Advances in Eicosanoid Research, reflects the current understanding of prostaglandins, thromboxanes and leukotrienes. The aim is to provide an introductory background to each topic and the most up-to-date information available. Although each book stands alone, the eicosanoids cut across many boundaries in their basic actions; selected chapters from each book in the series will provide illuminating and productive information for all readers which will advance their education and research. In the production of this series, I must acknowledge with pleasure my collaboration with editors and authors and the patient endeavours of Dr Michael Brewis and the staff at MTP Press.

Eicosanoids and Reproduction

Author : K. Hillier
Publisher : Springer
ISBN 13 : 9789401079433
Total Pages : 256 pages
Book Rating : 4.0/5 (794 download)

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Book Synopsis Eicosanoids and Reproduction by : K. Hillier

Download or read book Eicosanoids and Reproduction written by K. Hillier and published by Springer. This book was released on 2011-10-14 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: The original series, Advances in Prostaglandin Research, edited by Sultan M. M. Karim, was published by MTP Press in three volumes in 1975 and 1976. A glance at those books illustrates the progress that has been made since then. The thromboxanes were mentioned twice (first publication 1975) and prostacyclin not once (first publication 1976); leukotrienes were only on the horizon. The amazing generation of research data in the last 10-15 years has given new, broad insights into many areas, including asthma, inflammation, renal, cardiovascular and gastrointestinal diseases and in reproduction, and has led in some instances to real clinical benefit. This series, Advances in Eicosanoid Research, reflects the current understanding of prostaglandins , thromboxanes and leukotrienes. The aim is to provide an introductory background to each topic and the most up-to-date information available. Although each book stands alone, the eicosanoids cut across many boundaries in their basic actions; selected chapters from each book in the series will provide illuminating and productive information for all readers which will advance their education and research. In the production of this series, I must acknowledge with pleasure my collaboration with editors and authors and the patient endeavours of Dr Michael Brewis and the staff at MTP Press. KEITH HlLUER University of Southampton England ix Preface This book is an appraisal of areas in human reproduction where eicosanoid studies (prostaglandins, leukotrienes and thromboxanes) are contributing to physiological and pathological awareness and clinical advances.

The Role of Prostaglandins and Leukotrienes in the Physiology and Pathology of the Digestive Tract

Author :
Publisher :
ISBN 13 :
Total Pages : 102 pages
Book Rating : 4.:/5 (923 download)

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Book Synopsis The Role of Prostaglandins and Leukotrienes in the Physiology and Pathology of the Digestive Tract by :

Download or read book The Role of Prostaglandins and Leukotrienes in the Physiology and Pathology of the Digestive Tract written by and published by . This book was released on 2000 with total page 102 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Special Issue

Author :
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (641 download)

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Book Synopsis Special Issue by :

Download or read book Special Issue written by and published by . This book was released on 2000 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cooperation of Liver Cells in Health and Disease

Author : Z. Kmiec
Publisher : Springer Science & Business Media
ISBN 13 : 3642565530
Total Pages : 154 pages
Book Rating : 4.6/5 (425 download)

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Book Synopsis Cooperation of Liver Cells in Health and Disease by : Z. Kmiec

Download or read book Cooperation of Liver Cells in Health and Disease written by Z. Kmiec and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is only during the last decade that the functions of sinusoidal endothelial cells, Kupffer cells, hepatic stellate cells, pit cells and other intrahepatic lymphocytes have been better understood. The development of methods for isolation and co-culturing various types of liver cells has established that they communicate and cooperate via secretion of various intercellular mediators. This monograph summarizes multiple data that suggest the important role of cellular cross-talk for the functions of both normal and diseased liver. Special features of the book include concise presentation of the majority of detailed data in 19 tables. Original schemes allow for the clear illustration of complicated intercellular relationships. This is the first ever presentation of the newly emerging field of liver biology, which is important for hepatic function in health and disease and opens new avenues for therapeutic interventions.

The Role of Prostaglandins and Leukotrienes in the Physiology Ad Pathology of the Digestive Tract

Author :
Publisher :
ISBN 13 :
Total Pages : 101 pages
Book Rating : 4.:/5 (632 download)

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Book Synopsis The Role of Prostaglandins and Leukotrienes in the Physiology Ad Pathology of the Digestive Tract by :

Download or read book The Role of Prostaglandins and Leukotrienes in the Physiology Ad Pathology of the Digestive Tract written by and published by . This book was released on 2000 with total page 101 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Eicosanoids in the Cardiovascular and Renal Systems

Author : P.V. Halushka
Publisher : Springer
ISBN 13 : 9789401070713
Total Pages : 272 pages
Book Rating : 4.0/5 (77 download)

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Book Synopsis Eicosanoids in the Cardiovascular and Renal Systems by : P.V. Halushka

Download or read book Eicosanoids in the Cardiovascular and Renal Systems written by P.V. Halushka and published by Springer. This book was released on 2011-10-01 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: The original series, Advances in Prostaglandin Research, edited by Sultan M. M. Karim, was published by MTP Press in three volumes in 1975 and 1976. A glance at those books illustrates the progress that has been made since then. The thromboxanes were mentioned twice (first publication 1975) and prostacyclin not once (first publication 1976); leukotrienes were only on the horizon. The amazing generation of research data in the last 10-15 years has given new, broad insights into many areas, including asthma, inflammation, renaL cardiovascular and gastrointestinal diseases and in reproduction, and has led in some instances to real clinical benefit. This series, Advances in Eicosanoid Research, reflects the current understanding of prostaglandins, thromboxanes and leukotrienes. The aim is to provide an introductory background to each topic and the most up-to-date information available. Although each book stands alone, the eicosanoids cut across many boundaries in their basic actions; selected chapters from each book in the series will provide illuminating and productive information for all readers which will advance their education and research. In the production of this series, I must acknowledge with pleasure my collaboration with editors and authors and the patient endeavours of Dr Michael Brewis and the staff at MTP Press.

The Eicosanoids

Author : Peter Curtis-Prior
Publisher : John Wiley & Sons
ISBN 13 : 047002061X
Total Pages : 654 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis The Eicosanoids by : Peter Curtis-Prior

Download or read book The Eicosanoids written by Peter Curtis-Prior and published by John Wiley & Sons. This book was released on 2004-07-16 with total page 654 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive reference work, updated from the first edition, brings together the knowledge and expertise of contributors from around the world. It includes new topics such as prostaglandin synthetase enzyme, new synthetic eicosanoids, innovative analytical methods, the influence of cytokines in the regulation of synthesis and actions, newer eicosanoids that influence the cardiovascular system, and newly discovered roles in reproduction and interactions with nitric oxide. This book satisfies a surge of interest in prostaglandins—NSAIDS (e.g. aspirin) are the biggest selling drugs of all time, and the field has been refreshed by the advent of new types (selective COX-2 inhibitors, anti-leukotiene drugs).

Introduction to Basics of Pharmacology and Toxicology

Author : Abialbon Paul
Publisher : Springer Nature
ISBN 13 : 9813360097
Total Pages : 1156 pages
Book Rating : 4.8/5 (133 download)

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Book Synopsis Introduction to Basics of Pharmacology and Toxicology by : Abialbon Paul

Download or read book Introduction to Basics of Pharmacology and Toxicology written by Abialbon Paul and published by Springer Nature. This book was released on 2021-03-13 with total page 1156 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explains the pharmacological relationships between the various systems in the human body. It offers a comprehensive overview of the pharmacology concerning the autonomic, central, and peripheral nervous systems. Presenting up-to-date information on chemical mediators and their significance, it highlights the therapeutic aspects of several diseases affecting the cardiovascular, renal, respiratory, gastrointestinal, endocrinal, and hematopoietic systems. The book also includes drug therapy for microbial and neoplastic diseases. It also comprises sections on immunopharmacology, dermatological, and ocular pharmacology providing valuable insights into these emerging and recent topics. Covering the diverse groups of drugs acting on different systems, the book reviews their actions, clinical uses, adverse effects, interactions, and subcellular mechanisms of action. It is divided into 11 parts, subdivided into several chapters that evaluate the basic pharmacological principles that govern the different types of body systems. This book is intended for academicians, researchers, and clinicians in industry and academic institutions in pharmaceutical, pharmacological sciences, pharmacy, medical sciences, physiology, neurosciences, biochemistry, molecular biology and other allied health sciences.

Inflammation, 4 Volume Set

Author : Jean-Marc Cavaillon
Publisher : John Wiley & Sons
ISBN 13 : 3527338993
Total Pages : 1818 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Inflammation, 4 Volume Set by : Jean-Marc Cavaillon

Download or read book Inflammation, 4 Volume Set written by Jean-Marc Cavaillon and published by John Wiley & Sons. This book was released on 2018-02-20 with total page 1818 pages. Available in PDF, EPUB and Kindle. Book excerpt: The leading reference on this topic of increasing medical relevance is unique in offering unparalleled coverage. The editors are among the most respected researchers in inflammation worldwide and here have put together a prestigious team of contributors. Starting with the molecular basis of inflammation, from cytokines via the innate immune system to the different kinds of inflammatory cells, they continue with the function of inflammation in infectious disease before devoting a large section to the relationship between inflammation and chronic diseases. The book concludes with wound and tissue healing and options for therapeutic interventions. A must have for clinicians and biomedical researchers alike.

Drug Development

Author : Timothy S. Gaginella
Publisher : Springer Science & Business Media
ISBN 13 : 1592592023
Total Pages : 323 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Drug Development by : Timothy S. Gaginella

Download or read book Drug Development written by Timothy S. Gaginella and published by Springer Science & Business Media. This book was released on 1999-09-01 with total page 323 pages. Available in PDF, EPUB and Kindle. Book excerpt: The application of molecular techniques to gastroenterology continues to yield important advances in the development of drugs to treat gastrointestinal disorders. Important new drugs have emerged through the collaborative and complementary efforts of basic scientists, clinicians, and clinical researchers in academia and the pharmaceutical industry. The challenge has been exciting, with a few surprises along the way. Consider peptic ulcer disease as an example. The discovery of H receptors and the availability of potent and 2 selective H-receptor antagonists signaled the beginning of a new era 2 in the treatment of gastric hypersecretory states and peptic ulcers. Introduction of proton pump inhibitors offered another therapeutic option. Though H-receptor antagonists and proton pump inhibitors 2 are important and useful drugs, the discovery of the link between H. pylori infection and peptic ulcer disease has led to even more effective pharmacotherapeutic regimens. Our intent in Drug Development: Molecular Targets for GI Diseases is to bring together hands-on experts to review promising areas of gastrointestinal pharmacology. The contemporary topics covered, from a mechanistic viewpoint, are relevant to gastrointestinal inflammation and motility disorders. Authoritative opinions are offered on both future research directions and potential applications for new therapies.