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Project Ranch Hand 2 An Epidemiologic Investigation Of Health Effects In Air Force Personnel Following Exposure To Herbicides Baseline Mortality Study Results
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Book Synopsis Project RANCH HAND 2. An Epidemiologic Investigation of Health Effects in Air Force Personnel Following Exposure to Herbicides. Baseline Mortality Study Results by :
Download or read book Project RANCH HAND 2. An Epidemiologic Investigation of Health Effects in Air Force Personnel Following Exposure to Herbicides. Baseline Mortality Study Results written by and published by . This book was released on 1983 with total page 71 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1979 the United States Air Force (USAF) made the commitment to Congress and to the White House to conduct an epidemiologic study of the possible health effects from chemical exposure in Air Force personnel who conducted aerial herbicide dissemination missions in Vietnam (operation RANCH HAND). The purpose of this epidemiologic investigation is to determine whether long-term health effects exist and can be attributed to occupational exposure to herbicides. This study uses a matched cohort design in a nonconcurrent prospective setting, incorporating mortality, morbidity, and follow-up studies. The purpose of this report is to present the baseline mortality study results. As of December 31, 1982, 50 Ranch hand and 250 comparison subjects had died (certified on/before April 27, 1983). Data analysis showed that the mortality experience of the Ranch Hand group is nearly identical to that of this comparison group. However, this mortality report can in no way be regarded as conclusively negative since the study population may not yet have reached the latency period. Subsequent mortality reports will include additional analyses and will be updated annually for the next 20 years.
Book Synopsis Air Force Health Study (Project RANCH HAND II). An Epidemiologic Investigation of Health Effects in Air Force Personnel Following Exposure to Herbicides. Baseline Morbidity Study Results by : George D. Lathrop
Download or read book Air Force Health Study (Project RANCH HAND II). An Epidemiologic Investigation of Health Effects in Air Force Personnel Following Exposure to Herbicides. Baseline Morbidity Study Results written by George D. Lathrop and published by . This book was released on 1984 with total page 363 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1979 the United States Air Force (USAF) made the commitment to Congress and to the White House to conduct an epidemiologic study of the possible health effects from chemical exposure in Air Force personnel who conducted aerial herbicide dissemination missions in Vietnam (Operation RANCH HAND). The purpose of this epidemiologic investigation is to determine whether long-term health effects exist and can be attributed to occupational exposure to herbicides. This study uses a matched cohort design in a noncurrent prospective setting, incorporating mortality, morbidity, and follow-up studies. This report presents the results of health information on 2706 Ranch Handers and comparison individuals obtained by questionnaire and 2269 Ranch Handers and comparison individuals undergoing an extensive physical examination. This baseline report concludes that there is insufficient evidence to support a cause and effect relationship between herbicide exposure and adverse health in the Ranch Hand group at this time. The study has disclosed numerous medical findings, mostly of a minor or undetermined nature, that require detailed follow-up. In full context, the baseline study results should be viewed as reassuring to the Ranch Handers and to their families at this time.
Book Synopsis Project Ranch Hand II. An Epidemiologic Investigation of Health Effects in Air Force Personnel Following Exposure to Herbicides. Mortality Update 1984 by : William H. Wolfe
Download or read book Project Ranch Hand II. An Epidemiologic Investigation of Health Effects in Air Force Personnel Following Exposure to Herbicides. Mortality Update 1984 written by William H. Wolfe and published by . This book was released on 1984 with total page 55 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of the Ranch Hand II Study is to determine whether individuals involved in the aerial spraying of herbicides in Vietnam during the Ranch Hand operation have experienced increased deaths as a result of their participation in that program. The baseline mortality study was released in June 1983, and the baseline morbidity study in February 1984. Neither study demonstrated health effects that could be conclusively attributed to herbicide or dioxin exposure. The present study report describes the second mortality analyses. Deaths in the 1256 Ranch Hand and 6171 comparison subjects were determined. As of 31 December 1983, 54 Ranch Hand and 265 comparison subjects had died. Extensive statistical analyses were accomplished, as detailed in the report, to compare the death experience in the Ranch Hand population with the comparison group. In addition, death experience in these groups was compared to the 1978 U.S. White Male Mortality Experience, the 1978 Department of Defense Nondisability Retired Life Table, the mortality experience of the West Point Class of 1956, the USAF active duty personnel, and the active U.S. Civil Service population. The current mortality analyses did not reveal any statistically significant differences in mortality between the exposed and comparison groups. Continued mortality surveillance is recommended, since the study groups are still relatively young and healthy.
Book Synopsis Project Ranch Hand II. An Epidemiologic Investigation of Health Effects in Air Force Personnel Following Exposure to Herbicides. Mortality Update - 1985 by : William H. Wolfe
Download or read book Project Ranch Hand II. An Epidemiologic Investigation of Health Effects in Air Force Personnel Following Exposure to Herbicides. Mortality Update - 1985 written by William H. Wolfe and published by . This book was released on 1985 with total page 50 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of the Air Force Health Study is to determine whether individuals involved in the aerial spraying of herbicides in Vietnam during the Ranch Hand operation have experienced increased deaths as a result of their participation in that program. The Baseline Mortality Report was released in June 1983, the Baseline Morbidity Report in February 1984, and the first follow-up mortality study in December 1984. Neither study demonstrated health effects that could be conclusively attributed to herbicide or dioxin exposure. The present report describes the third mortality analyses. Deaths in the 1257 Ranch Hand and 6171 comparison subjects were determined. As of 31 December 1984, 55 Ranch Hand and 285 comparison subjects had died. Death certificates were obtained on all subjects. The current mortality analyses did not reveal any statistically significant differences in mortality between the exposed and comparison groups. Continued mortality surveillance is recommended since the study groups are still relatively young and healthy. While sufficient time may have elapsed for some clinically significant conditions to occur, additional time is necessary for other conditions to develop which may possibly be attributable to herbicide exposure. At this time, however, there is no evidence of increased mortality as a result of herbicide exposure in individuals who performed a Ranch Hand spray operations in Vietnam. Keywords: Epidemiologic investigation.
Book Synopsis An Epidemiologic Investigation of Health Effects in Air Force Personnel Following Exposure to Herbicides: Mortality Update - 1986 by : William H. Wolfe
Download or read book An Epidemiologic Investigation of Health Effects in Air Force Personnel Following Exposure to Herbicides: Mortality Update - 1986 written by William H. Wolfe and published by . This book was released on 1986 with total page 12 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of this study is to determine whether those individuals involved in spraying herbicides in Vietnam during the Ranch Hand operation have experienced any adverse health effects as a result of their participation in that program. The study is designed to evaluate both the mortality (death) and morbidity (disease) in these individuals over a 20 year period beginning in 1982. The baseline mortality report was released in June 1983 and the baseline morbidity report in February 1984. Follow-up mortality reports were released in 1984 and 1985. This study has so far failed to demonstrate health effects which can be conclusively attributed to herbicide or dioxin exposure. This report summary statistics only for cumulative deaths occurring up to 31 Dec 1985. These data were not statistically analyzed since the 4 Ranch Hand and 27 Comparison deaths since the last report would not alter the results of the last analysis. As of 31 Dec 1985, 59 Ranch Hand and 312 comparison subjects had died. The small number of deaths since the last analysis suggests that the findings of the last report are still valid: there are no overall statistically significant differences between the Ranch Handers and their matched comparisons as regards mortality. Continued mortality surveillance is recommended, since these study groups are still relatively young and healthy. While sufficient time may have elapsed for some clinically significant condition to occur, additional time is necessary for other conditions, which may possibly be attributable to herbicide exposure, to develop.
Book Synopsis An Epidemiologic Investigation of Health Effects in Air Force Personnel Following Exposure to Herbicides by : William H. Wolfe
Download or read book An Epidemiologic Investigation of Health Effects in Air Force Personnel Following Exposure to Herbicides written by William H. Wolfe and published by . This book was released on 1989 with total page 40 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis An Epidemiologic Investigation of Health Effects in Air Force Personnel Following Exposure to Herbicides by :
Download or read book An Epidemiologic Investigation of Health Effects in Air Force Personnel Following Exposure to Herbicides written by and published by . This book was released on 1995 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report represents the results from an epidemiologic study to determine whether adverse health effects attributable to Herbicide Orange exist in Vietnam veterans who participated in Operation Ranch Hand. Data were analyzed for 12 clinical areas. The analysis focused on group differences between the exposed (Ranch Hand) and unexposed (Comparison) cohorts, as well as on the association of each health-related endpoint with extrapolated initial and current serum dioxin levels. Findings in this report reveal a consistent relationship between dioxin and body fat that was initially noted in the analysis of the 1987 examination results. Cholesterol and the cholesterol to HDL ratio were found to be associated with current serum dioxin levels. Evidence for a possible association between glucose intolerance, impaired insulin production, and dioxin exposure was revealed, but cause and effect remain to be established. Also revealed was a significant association between selected peripheral pulses and dioxin exposure, and a significant difference in self-perceived health status between Ranch Hands and Comparisons (although possible due to bias). Other health endpoints revealed no consistent patterns within or across clinical areas that were suggestive of health detriment due to dioxin exposure.
Book Synopsis An Epidemiologic Investigation of Health Effects in Air Force Personnel Following Exposure to Herbicides. Volume 2. First Followup Examination Results by : G. D. Lathrop
Download or read book An Epidemiologic Investigation of Health Effects in Air Force Personnel Following Exposure to Herbicides. Volume 2. First Followup Examination Results written by G. D. Lathrop and published by . This book was released on 1987 with total page 459 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report represent the result of the health assessment of the 1,016 Ranch Hands and the 1,293 Comparisons who participated in the 1985 followup examination of the Air Force health Study. The purpose of the study is to determine whether long-term health effects exist and can be attributed to occupational exposure to herbicides. The results show a subtle but consistent narrowing of medical differences between the two groups since the Baseline study in 1982, however, the Ranch Hands continue to manifest slightly more minor adverse health conditions than the Comparisons. Continued surveillance of these groups is indicated. The report concludes that there is not sufficient evidence to implicate a causal relationship between herbicide exposure and adverse health in the Ranch Hand group. Keywords: Epidemiologic investigation, Phenoxy herbicides, Herbicide orange, Dioxin, Morbidity, Health surveys, Air Force health study.
Book Synopsis The Air Force Health Study: An Epidemiologic Investigation of Health Effects in Air Force Personnel Following Exposure to Herbicides. Mortality Update 1996 by :
Download or read book The Air Force Health Study: An Epidemiologic Investigation of Health Effects in Air Force Personnel Following Exposure to Herbicides. Mortality Update 1996 written by and published by . This book was released on 1996 with total page 33 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of the Air Force Health Study is to determine whether those individuals involved in the spraying of herbicides in Vietnam during the Ranch Hand operation have experienced any adverse health effects as a result of their participation in that program. The study is designed to evaluate both the mortality (death) and morbidity (disease) in these individuals over a 20-year period beginning in 1982. The Baseline Mortality Report was released in June 1983, the Baseline Morbidity Report in February 1984. Follow-up mortality reports were released in 1984, 1985, 1986, 1989, 1991, 1993 and 1994. This study has not demonstrated health effects which can be conclusively attributed to herbicide or dioxin exposure. In summary, the overall all-cause mortality experience of the Ranch Hands is not significantly different from that expected. As of 31 December 1993, 118 (9.4%) of the 1261 Ranch Hands have died; the expected number of deaths is 119.95. The observed and expected numbers of deaths among all Ranch Hands were not significantly different for accidental deaths, suicides and deaths caused by malignant neoplasms and circulatory system diseases. However, there were borderline significant increased numbers of Ranch Hand deaths due to circulatory system diseases in nonflying enlisted Ranch Hands. In contrast to previous reports, deaths caused by digestive disease and deaths due to ill-defined and unknown causes in enlisted flyers are no longer significantly increased.
Book Synopsis An Epidemiologic Investigation of Health Effects in Air Force Personnel Following Exposure to Herbicides. Mortality Update - 1989 by :
Download or read book An Epidemiologic Investigation of Health Effects in Air Force Personnel Following Exposure to Herbicides. Mortality Update - 1989 written by and published by . This book was released on 1989 with total page 131 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of the Air Force Health Study is to determine whether those individuals involved in the spraying of herbicides in Vietnam during the Ranch Hand operation have experienced any adverse health effects as a result of their participation in that program. The study is designed to evaluate both the mortality (death) and morbidity (disease) in these individuals over a 20-year period beginning in 1982. The Baseline Mortality Report was released in June 1983, the Baseline Morbidity Report in February 1984. Follow-up mortality reports were released in 1984, 1985, and 1986. This study has not demonstrated health effects which can be conclusively attributed the overall cumulative mortality of the Ranch Hands remains statistically indistinguishable from that of both their matched Comparisons and the entire Comparison population, although there is a statistically significant increasing trend in post-1983 death rates among Ranch Hand flying officers and statistically significant increase in Ranch hand digestive system deaths relative to the Comparison population; These findings are not suggestive of a herbicide effect. Ranch Hands are equivalent to all Comparisons in cumulative accidental malignant neoplasm and circulatory system mortality. Keywords: Epidemiology, Toxicity.
Book Synopsis An Epidemiologic Investigation of Health Effects in Air Force Personnel by : Royce Moser
Download or read book An Epidemiologic Investigation of Health Effects in Air Force Personnel written by Royce Moser and published by . This book was released on 198? with total page 62 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis An Epidemiologic Investigation of Health Effects in Air Force Personnel Following Exposure to Herbicides by : USAF School of Aerospace Medicine. Epidemiology Division
Download or read book An Epidemiologic Investigation of Health Effects in Air Force Personnel Following Exposure to Herbicides written by USAF School of Aerospace Medicine. Epidemiology Division and published by . This book was released on 1987 with total page 52 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis ˜Anœ epidemiologic investigation of health effects in air force personnel following exposure to herbicides by :
Download or read book ˜Anœ epidemiologic investigation of health effects in air force personnel following exposure to herbicides written by and published by . This book was released on 1984 with total page 46 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis An Epidemiologic Investigation of Health Effects in Air Force Personnel Following Exposure to Herbicides. Mortality Update 1993 by :
Download or read book An Epidemiologic Investigation of Health Effects in Air Force Personnel Following Exposure to Herbicides. Mortality Update 1993 written by and published by . This book was released on 1993 with total page 37 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of the Air Force Health Study is to determine whether those individuals involved in the spraying of herbicides in Vietnam during the Ranch Hand operation have experienced any adverse health effects as a result of their participation in that program. The study is designed to evaluate both the mortality (death) and morbidity (disease) in these individuals over a 20-year period beginning in 1982. The overall all-cause mortality experience of the Ranch Hands is not significantly different from the expected. As of 31 December 1991, 106 (8.4%) of the 1261 Ranch Hands have died; the expected number of deaths is 103. The observed and expected numbers of deaths were not significantly different for accidental deaths, suicides and deaths caused by malignant neoplasms and circulatory system diseases. However, there were significantly increased numbers of Ranch Hand deaths due to digestive diseases and, in nonflying enlisted personnel, circulatory system diseases. Both of these increases have been noted in previous reports and both are, as yet, unexplained.
Book Synopsis An Epidemiologic Investigation of Health Effects in Air Force Personnel Following Exposure to Herbicides by :
Download or read book An Epidemiologic Investigation of Health Effects in Air Force Personnel Following Exposure to Herbicides written by and published by . This book was released on 2000 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: "This report summarizes results from the Air Force Health Study (AFHS). The AFHS is an epidemiological study to determine whether adverse health effects attributable to exposure to herbicides exist in veterans of Operation Ranch Hand. Operation Ranch Hand was the unit responsible for the aerial spraying of herbicides, including Herbicide Orange, in Vietnam from 1961 to 1971. A Comparison cohort comprised Air Force veterans who served in Southeast Asia during the same time period that the Ranch Hand unit was active and who were not involved with spraying herbicides. The summarized data were collected during a physical examination administered between May 1997 and April 1998. Of 1,149 eligible Ranch Hands, 870 (75.7%) participated and of 1,761 eligible Comparisons, 1,251 (71.0%) participated. Statistical analyses assessed differences between Ranch Hands and Comparisons and associations between health-related endpoints and extrapolated initial dioxin, dioxin exposure category (Comparisons, background Ranch Hands, low Ranch Hands, high Ranch Hands), and dioxin measured in 1987. The study has insufficient statistical power to assess increases in the risk of rare diseases, such as soft tissue sarcoma. Diabetes and cardiovascular abnormalities represent the most important dioxin-related health problems seen. From a public health perspective, these two areas demand the greatest attention."--Abstract.
Book Synopsis Epidemiologic Investigation of Health Effects in Air Force Personnel Following Exposure to Herbicides: Study Protocol by :
Download or read book Epidemiologic Investigation of Health Effects in Air Force Personnel Following Exposure to Herbicides: Study Protocol written by and published by . This book was released on 1982 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1979 the United States Air Force (USAF) made the commitment to Congress and to the White House to conduct an epidemiologic study of the possible health effects from chemical exposure in Air Force personnel who conducted aerial herbicide dissemination missions in Vietnam (Operation RANCH HAND). The purpose of this epidemiologic investigation is to determine whether long-term health effects exist and can be attributed to occupational exposure to herbicides. This study uses a matched cohort design in a noncurrent prospective setting incorporating mortality, morbidity, and followup studies, Detailed computer searches of Air Force personnel records, with several cross-referencing techniques, have ensured total ascertainment of the RANCH HAND population. The unique circumstances of exposure in this population of 1264 individuals will permit a semiquantitative estimate of exposure. A comparison group will be formed from a population of 23,978 flight crew members and support personnel who were assigned to duty in Southeast Asia (SEA), but were not occupationally exposed to herbicides. These individuals will be matched to RANCH HAND personnel for the variables of age, type of job, and race. Since both the exposed subjects and their selected controls performed similar combat or combat-related jobs, many of the physical and psychophysiologic effects of combat stress and the SEA environment will also be equivalent in the two groups.
Book Synopsis Veterans and Agent Orange by : Institute of Medicine
Download or read book Veterans and Agent Orange written by Institute of Medicine and published by National Academies Press. This book was released on 2000-10-30 with total page 77 pages. Available in PDF, EPUB and Kindle. Book excerpt: In response to the concerns voiced by Vietnam veterans and their families, Congress called upon the National Academy of Sciences (NAS) to review the scientific evidence on the possible health effects of exposure to Agent Orange and other herbicides. This call resulted in the creation of the first NAS Institute of Medicine Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides in 1992. The committee published its initial findings in the 1994 report Veterans and Agent Orange: Health Effects of Herbicides Used in Vietnam. This report is the result of a 1999 request from the Department of Veterans Affairs (DVA) under the aegis of the Veterans and Agent Orange research program. Specifically, DVA asked the committee to examine evidence regarding the association, if any, between Type 2 diabetes and exposure to dioxin and other chemical compounds in herbicides used in Vietnam. Veterans and Agent Orange: Herbicide/Dioxin Exposure and Type 2 Diabetes reviews the scientific evidence regarding the association, if any, between Type 2 diabetes1 and exposure to dioxin2 and other chemical compounds in herbicides used in Vietnam. This report examines, to the extent that available data permitted meaningful determinations, (1) whether a statistical association with herbicide exposure exists, taking into account the strength of the scientific evidence and the appropriateness of the statistical and epidemiologic methods used to detect the association; (2) the increased risk of the disease among those exposed to herbicides during Vietnam service; and (3) whether there is a plausible biological mechanism or other evidence of a causal relationship between herbicide exposure and the disease.
