Progress in Biological Chirality

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Publisher : Elsevier
ISBN 13 : 0080474039
Total Pages : 445 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Progress in Biological Chirality by : Gyula Palyi

Download or read book Progress in Biological Chirality written by Gyula Palyi and published by Elsevier. This book was released on 2004-12-13 with total page 445 pages. Available in PDF, EPUB and Kindle. Book excerpt: Following on from Advances in BioChirality, Progress in Biological Chirality provides a unique summary and review of the most recent developments in the field of biochirality. Living organisms use only one enantiomer of chiral molecules in the majority of biologically important processes. The exact origin and mechanisms for this surprising selectivity are not yet known. This book discusses current research aimed at identifying the scientific reasons that may contribute to this phenomenon. Progress in Biological Chirality takes an interdisciplinary approach to this exciting field, covering a wide range of topics, such as, theory, palaeontology and food technology, to name but a few. This book presents findings via a broad spectrum of scientific approaches making it an excellent overview of Biological Chirality, suitable for postgraduate students, practitioners and researchers in the field of chemistry, biochemistry, biology, palaeontology, and food science with an interest in Chirality. - This book contains 32 chapters written by Authors, who are leading authorities in the field - Presents the most recent research taking place in this highly challenging field - Contains both reference material for the specialist and provides an overview for those who are interested in the fundamental problems of biology and chemistry

Chiral Drugs

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Publisher : John Wiley & Sons
ISBN 13 : 1118075633
Total Pages : 469 pages
Book Rating : 4.1/5 (18 download)

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Book Synopsis Chiral Drugs by : Guo-Qiang Lin

Download or read book Chiral Drugs written by Guo-Qiang Lin and published by John Wiley & Sons. This book was released on 2011-08-08 with total page 469 pages. Available in PDF, EPUB and Kindle. Book excerpt: An integrated view of chiral drugs from concept and synthesisto pharmaceutical properties Chirality greatly influences a drug's biological and pharmacological properties. In an effort to achieve more predictable results from chiral drugs, the Food and Drug Administration now requires that these medicines be as pure as possible, which places great demands on drug synthesis, purification, analysis, and testing. To assist researchers in acquiring the essential knowledge to meet these rigid guidelines, Chiral Drugs focuses on three vital chiral technologies asymmetric synthesis, biocatalytic process, and chiral resolution to offer details on the basic concepts, key developments, and recent trends in chiral drug discovery, along with: The history of chiral drugs development and industrial applications of chiral technologies A section listing twenty-five approved or advanced-trial chiral drugs that lists each drug name, chemical name and properties, a representative synthetic pathway, pharmacological characterizations, and references An interdisciplinary approach combining synthetic organic chemistry, medicinal chemistry, and pharmacology Nearly two-thirds of the drugs on today's market are chiral drugs. Reducing and eliminating their negative characteristics is an ongoing and serious challenge for the pharmaceutical industry. With its well-balanced approach to covering each important aspect of chirality, Chiral Drugs champions important strategies for tipping the medical scale in a positive direction for the production of more effective and safer drugs.

Asymmetric Synthesis with Chemical and Biological Methods

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Publisher : John Wiley & Sons
ISBN 13 : 3527610634
Total Pages : 470 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Asymmetric Synthesis with Chemical and Biological Methods by : Dieter Enders

Download or read book Asymmetric Synthesis with Chemical and Biological Methods written by Dieter Enders and published by John Wiley & Sons. This book was released on 2007-06-27 with total page 470 pages. Available in PDF, EPUB and Kindle. Book excerpt: Edited by two of the leading researchers in the field, this book provides a deep, interdisciplinary insight into stoichiometric and catalytic reactions in this continuously expanding area. A plethora of top German scientists with an international reputation covers various aspects, from classical organic chemistry to process development, and from the theoretical background to biological methods using enzymes. Throughout the focus is on the development of new synthetic methods in asymmetric synthesis, the synthesis of natural and bioactive compounds and the latest developments in both chemical and biological methods of catalysis, as well as the investigation of special technical and biotechnical aspects.

Chirality in Drug Design and Development

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Publisher : CRC Press
ISBN 13 : 0824751094
Total Pages : 406 pages
Book Rating : 4.8/5 (247 download)

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Book Synopsis Chirality in Drug Design and Development by : Indra K. Reddy

Download or read book Chirality in Drug Design and Development written by Indra K. Reddy and published by CRC Press. This book was released on 2004-03-15 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covering every essential element in the development of chiral products, this reference provides a solid overview of the formulation, biopharmaceutical characteristics, and regulatory issues impacting the production of these pharmaceuticals. It supports researchers as they evaluate the pharmacodynamic, pharmacokinetic, and toxicological characteristics of specific enantiomers and chiral drug compounds and addresses in one convenient reference all the major challenges pertaining to drug chirality that have been neglected in the literature. Chirality in Drug Design and Development collects the latest studies from an interdisciplinary team of experts on chiral drug design.

Separation Methods in Drug Synthesis and Purification

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Publisher : Elsevier
ISBN 13 : 0080541097
Total Pages : 613 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Separation Methods in Drug Synthesis and Purification by : Klara Valko

Download or read book Separation Methods in Drug Synthesis and Purification written by Klara Valko and published by Elsevier. This book was released on 2000-10-13 with total page 613 pages. Available in PDF, EPUB and Kindle. Book excerpt: Separation Methods in Drug Synthesis and Purification

Advances in BioChirality

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Publisher : Elsevier
ISBN 13 : 0080526624
Total Pages : 417 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Advances in BioChirality by : C. Zucchi

Download or read book Advances in BioChirality written by C. Zucchi and published by Elsevier. This book was released on 1999-09-08 with total page 417 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chirality is a fundamental, persistent, but often overlooked feature of all living organisms on the molecular level as well as on the macroscopic scale. The high degree of preference for only one of two possible mirror image forms in Nature, often called biological homochirality is a puzzling, and not yet fully understood, phenomenon. This book covers biological homochirality from an interdisciplinary approach - contributions range from synthetic chemists, theoretical topologists and physicists, from palaeontologists and biologists to space scientists and representatives of the pharmaceutical and materials industries. Topics covered include - theory of biochirality, origins of biochirality, autocatalysis with amplification of chirality, macroscopic (present) biochirality, fossil records of chiral organisms - paleochirality, extraterrestrial origin of chirality, exceptions to the rule of biological homochirality, D-amino acids, chemical transfer of chirality, PV effects, and polarised radiation chemistry.

Biological Chirality

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Publisher : Academic Press
ISBN 13 : 0128123389
Total Pages : 270 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Biological Chirality by : Gyula Palyi

Download or read book Biological Chirality written by Gyula Palyi and published by Academic Press. This book was released on 2019-11-06 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological Chirality describes this occurrence, its history, and early research around the topic. The work covers analytical methods for observing the phenomenon, providing current techniques and practice and discussing the asymmetric morphology of certain living organisms, such as the position of the heart and liver in humans and the exceptions to biological homochirality seen in D-Amino Acids. In addition, it explores the requirement of enantioselectivity prepared pharmaceuticals to address enantioselectivities biomolecules, a major challenge in today's organic chemistry. Finally, the work considers the possible origin of biological homochirality, as well as the outlook for future research in this area. - Describes the history of biological chirality research, its possible origins, and future exploration areas - Discusses asymmetric exceptions in morphology and D-Amino Acids - Explores the critical implications of enantioselective biomolecules for preparative organic chemistry with a goal of developing effective pharmaceuticals

Chiral Nanomaterials

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Publisher : John Wiley & Sons
ISBN 13 : 3527337571
Total Pages : 300 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Chiral Nanomaterials by : Zhiyong Tang

Download or read book Chiral Nanomaterials written by Zhiyong Tang and published by John Wiley & Sons. This book was released on 2018-03-05 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thorough and up-to-date, this book presents recent developments in this exciting research field. To begin with, the text covers the fabrication of chiral nanomaterials via various synthesis methods, including electron beam lithography, ion beam etching, chemical synthesis and biological DNA directed assembly. This is followed by the relevant theory and reaction mechanisms, with a discussion of the characterization of chiral nanomaterials according to the optical properties of metal nanoparticles, semiconductor nanocrystals, and nanoclusters. The whole is rounded off by a summary of applications in the field of catalysis, sensors, and biomedicine. With its comprehensive yet concise coverage of the whole spectrum of research, this is invaluable reading for senior researchers and entrants to the field of nanoscience and materials science.

Nonlinear Optical Polarization Analysis in Chemistry and Biology

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Publisher : Cambridge University Press
ISBN 13 : 052151908X
Total Pages : 499 pages
Book Rating : 4.5/5 (215 download)

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Book Synopsis Nonlinear Optical Polarization Analysis in Chemistry and Biology by : Garth J. Simpson

Download or read book Nonlinear Optical Polarization Analysis in Chemistry and Biology written by Garth J. Simpson and published by Cambridge University Press. This book was released on 2017-03-24 with total page 499 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents a clear systematic molecular-based description of nonlinear optical polarization analysis of chemical and biological assemblies.

Amplification of Chirality

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Publisher : Springer Science & Business Media
ISBN 13 : 3540778691
Total Pages : 211 pages
Book Rating : 4.5/5 (47 download)

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Book Synopsis Amplification of Chirality by : Kenso Soai

Download or read book Amplification of Chirality written by Kenso Soai and published by Springer Science & Business Media. This book was released on 2009-11-04 with total page 211 pages. Available in PDF, EPUB and Kindle. Book excerpt: Amplification of Chirality presents critical reviews of the present position and future trends in modern chemical research. The book contains short and concise reports on chemistry. Each is written by the world renowned experts. Still valid and useful after 5 or 10 years, more information as well as the electronic version of the whole content available at: springerlink.com.

Exploring the Origin, Extent, and Future of Life

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Publisher : Cambridge University Press
ISBN 13 : 1139480677
Total Pages : 337 pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis Exploring the Origin, Extent, and Future of Life by : Constance M. Bertka

Download or read book Exploring the Origin, Extent, and Future of Life written by Constance M. Bertka and published by Cambridge University Press. This book was released on 2009-09-03 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: Where did we come from? Are we alone? Where are we going? These are the questions that define the field of astrobiology. New discoveries about life on Earth, the increasing numbers of extrasolar planets being identified, and the technologies being developed to locate and characterize Earth-like planets around other stars are continually challenging our views of nature and our connection to the rest of the universe. In this book, philosophers, historians, ethicists, and theologians provide the perspectives of their fields on the research and discoveries of astrobiology. A valuable resource for graduate students and researchers, the book provides an introduction to astrobiology, and explores subjects such as the implications of current origin of life research, the possible discovery of extraterrestrial microbial life, and the possibility of altering the environment of Mars.

Mirror-Image Asymmetry

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Publisher : John Wiley & Sons
ISBN 13 : 047058887X
Total Pages : 272 pages
Book Rating : 4.4/5 (75 download)

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Book Synopsis Mirror-Image Asymmetry by : James P. Riehl

Download or read book Mirror-Image Asymmetry written by James P. Riehl and published by John Wiley & Sons. This book was released on 2011-04-22 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: An overview of the importance and consequences of asymmetry from molecules to the macroscopic world As scientists have become more capable of probing the structure of three-dimensional objects at the molecular level, the need to understand the concept and the consequences of mirror-image asymmetry—chirality—has increased enormously. Written at an introductory level, Mirror-Image Asymmetry provides an overview of the importance and effects of asymmetry from the atomic and molecular world of physics and chemistry to the organisms and structures that we see and use in our everyday life. The reader will develop a broad appreciation of three-dimensional asymmetry from the microscopic molecular world to the macroscopic world of handedness, automobile driving, windmills, sports, and similar phenomena. The book features: An introduction to basic definitions and the nomenclature of asymmetric and dissymmetric molecules Up-to-date examples of the importance and consequences of asymmetry in modern drug applications, current theories of the origin of asymmetry in nature, and examples of molecular asymmetry in smell, taste, and insect communication Many illustrations, chemical structures, and photographs that enable the reader to connect the actual asymmetrical structures to the different phenomena that depend on structural asymmetry In the 150 years since Louis Pasteur discovered asymmetry in molecular structures, scientists have made great progress in understanding how interactions between chiral molecules influence biochemical processes. This knowledge is leading to very sophisticated asymmetric synthetic techniques that have greatly benefitted many research groups especially those in the pharmaceutical industry. This guide to the role of molecular and macroscopic chirality will inspire students and scientists in chemistry, biology, physics, and drug discovery.

Chiral Analysis

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Publisher : Elsevier
ISBN 13 : 0080469280
Total Pages : 721 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Chiral Analysis by : Kenneth W. Busch

Download or read book Chiral Analysis written by Kenneth W. Busch and published by Elsevier. This book was released on 2011-10-13 with total page 721 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chiral Analysis covers an important area of analytical chemistry of relevance to a wide variety of scientific professionals. The target audience is scientific professionals with an undergraduate background in chemistry or a related discipline, specifically organic chemists, researchers in drug discovery, pharmaceutical researchers involved with process analysis or combinatorial libraries, and graduate students in chemistry. Chapters have been written with the nonspecialist in mind so as to be self-contained.* Broad coverage - spectroscopic and separation methods covered in a single volume* Up-to-date and detailed review of the various techniques available and/or under development in this field* Contributions from leading experts in the field

Chirality in Supramolecular Assemblies

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Publisher : John Wiley & Sons
ISBN 13 : 1118867319
Total Pages : 722 pages
Book Rating : 4.1/5 (188 download)

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Book Synopsis Chirality in Supramolecular Assemblies by : F. Richard Keene

Download or read book Chirality in Supramolecular Assemblies written by F. Richard Keene and published by John Wiley & Sons. This book was released on 2017-01-03 with total page 722 pages. Available in PDF, EPUB and Kindle. Book excerpt: Supramolecular chemistry deals with the organisation of molecules into defined assemblies using non-covalent interactions, including weaker and reversible interactions such as hydrogen bonds, and metal-ligand interactions. The aspect of stereochemistry within such chemical architectures, and in particular chirality, is of special interest as it impacts on considerations of molecular recognition, the development of functional materials, the vexed question of homochirality, nanoscale effects of interactions at interfaces, biocatalysis and enzymatic catalysis, and applications in organic synthesis. Chirality in Supramolecular Assemblies addresses many of these aspects, presenting a broad overview of this important and rapidly developing interdisciplinary field. Topics covered include: Origins of molecular and topological chirality Homochirogenesis Chirality in crystallinity Host-guest behavior Chiral influences in functional materials Chirality in network solids and coordination solids Aspects of chirality at interfaces Chirality in organic assemblies Chirality related to biocatalysis and enzymes in organic synthesis. This book is a valuable reference for researchers in the molecular sciences, materials science and biological science working with chiral supramolecular systems. It provides summaries and special insights by acknowledged international experts in the various fields.

Advances in Asymmetric Autocatalysis and Related Topics

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Publisher : Academic Press
ISBN 13 : 0128128259
Total Pages : 393 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Advances in Asymmetric Autocatalysis and Related Topics by : Gyula Palyi

Download or read book Advances in Asymmetric Autocatalysis and Related Topics written by Gyula Palyi and published by Academic Press. This book was released on 2017-05-18 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Asymmetric Autocatalysis and Related Topics provides various viewpoints on the important developments in asymmetric autocatalysis that have occurred in the past few years, also including brand new information in the field. Asymmetric autocatalysis is a chemical reaction which leads from achiral starting materials to chiral products, and in which the product accelerates its own formation reaction (conventional catalysis) and promotes the prevalence of its own chiral configuration (asymmetric induction). The combination of these two effects in the same reaction was unprecedented before 1995 when it was first described by Kenso SOAI at the Tokyo University of Science. Since then, several new combinations of this effect have been found, most intriguingly the possibility of absolute asymmetric synthesis, which is the spontaneous formation of the excess of one of the enantiomers of the product, a dream of organic chemists for more than a century. The book contains expert-contributed chapters that describe the most exciting recent developments in the field of the Soai reaction and in related topics, ranging from mechanistic studies and theoretical research, to very practical problems in chiral syntheses and products. - Features contributions from global experts, including several chapters from Kenso Soai and expert colleagues - Focuses on recent developments in the field of asymmetric autocatalysis and newly reported findings - Explores the Soai reaction, new developments, and the light it sheds on homochirality in certain biomolecules

Electronic and Magnetic Properties of Chiral Molecules and Supramolecular Architectures

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Publisher : Springer
ISBN 13 : 364218104X
Total Pages : 323 pages
Book Rating : 4.6/5 (421 download)

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Book Synopsis Electronic and Magnetic Properties of Chiral Molecules and Supramolecular Architectures by : Ron Naaman

Download or read book Electronic and Magnetic Properties of Chiral Molecules and Supramolecular Architectures written by Ron Naaman and published by Springer. This book was released on 2011-02-15 with total page 323 pages. Available in PDF, EPUB and Kindle. Book excerpt: Time-dependent density functional response theory for electronic chiroptical properties of chiral molecules; by Jochen Autschbach, Lucia Nitsch–Velasquez, and Mark Rudolph * Chiroptical Properties of Charge-Transfer Compounds; by Yoshihisa Inoue, Tadashi Mori * G-C content independent long-range charge transfer through DNA; by Tetsuro Majima * Induced chirality in porphiryn aggregates: the role of weak and strong interactions; by Roberto Purrello * Vibrational circular dichroism spectroscopy of chiral molecules in solution; by Yunjie Xu * Magneto-electric properties of self-assembled monolayers of chiral molecules; by Zeev Vager and Ron Naaman * Theory of adsorption induced chirality and electron transfer through chiral systems; by Spiros Skourtis and David Beratan * Chiral-selective surface chemistry induced by spin-polarized secondary electrons; by Richard Rosenberg

Supramolecular Chirogenesis in Chemical and Related Sciences

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Publisher : Frontiers Media SA
ISBN 13 : 2889668339
Total Pages : 179 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Supramolecular Chirogenesis in Chemical and Related Sciences by : Victor Borovkov

Download or read book Supramolecular Chirogenesis in Chemical and Related Sciences written by Victor Borovkov and published by Frontiers Media SA. This book was released on 2021-06-01 with total page 179 pages. Available in PDF, EPUB and Kindle. Book excerpt: