Proceedings Of The 10th Annual Targeted Therapies Of The Treatment Of Lung Cancer 2010

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Targeted Therapies for Lung Cancer

Author : Ravi Salgia
Publisher : Springer
ISBN 13 : 3030178323
Total Pages : 244 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Targeted Therapies for Lung Cancer by : Ravi Salgia

Download or read book Targeted Therapies for Lung Cancer written by Ravi Salgia and published by Springer. This book was released on 2019-06-26 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contextualizes translational research and provides an up to date progress report on therapies that are currently being targeted in lung cancer. It is now well established that there is tremendous heterogeneity among cancer cells both at the inter- and intra-tumoral level. Further, a growing body of work highlights the importance of targeted therapies and personalized medicine in treating cancer patients. In contrast to conventional therapies that are typically administered to the average patient regardless of the patient’s genotype, targeted therapies are tailored to patients with specific traits. Nonetheless, such genetic changes can be disease-specific and/or target specific; thus, the book addresses these issues manifested in the somatically acquired genetic changes of the targeted gene. Each chapter is written by a leading medical oncologist who specializes in thoracic oncology and is devoted to a particular target in a specific indication. Contributors provide an in-depth review of the literature covering the mechanisms underlying signaling, potential cross talk between the target and downstream signaling, and potential emergence of drug resistance.

Targeted Therapies in Breast Cancer

Author : Gw Sledge
Publisher : Clinical Pub
ISBN 13 : 9781846920660
Total Pages : 0 pages
Book Rating : 4.9/5 (26 download)

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Book Synopsis Targeted Therapies in Breast Cancer by : Gw Sledge

Download or read book Targeted Therapies in Breast Cancer written by Gw Sledge and published by Clinical Pub. This book was released on 2012-06 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new volume updates the reader on selected areas of targeted therapy in breast cancer, with special emphasis on chemoprevention strategies, drug resistance, biomarkers, combination chemotherapy, angiogenesis inhibition and pharmacogenomics in the context of clinical efficacy. This selected review of targeted therapies will guide the reader on effective treatment as part of an integrated programme of patient management.

Targeted Therapies in Cancer

Author : Marc Lacroix
Publisher : Nova Science Publishers
ISBN 13 : 9781634846684
Total Pages : 0 pages
Book Rating : 4.8/5 (466 download)

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Book Synopsis Targeted Therapies in Cancer by : Marc Lacroix

Download or read book Targeted Therapies in Cancer written by Marc Lacroix and published by Nova Science Publishers. This book was released on 2016 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Besides surgery, radiation therapy, endocrine therapy or chemotherapy, which were widely used in cancer patients for decades, the 21st century has seen the emergence of "targeted" therapy, resulting from the identification of molecular pathways in cells and their alterations in tumors. An increasing number of compounds targeting specific molecules or cancer cells have been developed and, for some of them, approved by the United States Food and Drug Administration (FDA) as well as other regulators in EU and Japan Additional new and more efficient types of compounds, are still in clinical trials, but are expected to gain future approval. More than eighty FDA-approved targeted therapies are described here, along with about eighty other promising compounds. These drugs are members of various therapy classes, including tyrosine kinase inhibitors; serine/threonine kinase inhibitors; dual specificity kinase inhibitors; lipid kinase inhibitors; poly ADP ribose polymerase inhibitors; monoclonal antibodies; microtubule targeting agents; histone deacetylase inhibitors; proteasome inhibitors; antimetabolites; immunomodulatory agents; DNA methyltransferase inhibitors; hedgehog pathway inhibitors; enzymes; protein translation inhibitors; vaccines, oncolytic viruses; chimeric antigen receptor T-cells (CAR-T); and so on. A series of "companion" diagnostics intended to be used as an indication for specific therapies, and approved to this aim are also mentioned. The book aims to present the broad landscape of compounds and companion diagnostics that are expected to pave the way towards a future of hope for cancer patients.

How Tobacco Smoke Causes Disease

Author : United States. Public Health Service. Office of the Surgeon General
Publisher :
ISBN 13 :
Total Pages : 728 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis How Tobacco Smoke Causes Disease by : United States. Public Health Service. Office of the Surgeon General

Download or read book How Tobacco Smoke Causes Disease written by United States. Public Health Service. Office of the Surgeon General and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.

Targeted Therapies in Oncology

Author : Giuseppe Giaccone
Publisher : CRC Press
ISBN 13 : 1842145460
Total Pages : 498 pages
Book Rating : 4.8/5 (421 download)

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Book Synopsis Targeted Therapies in Oncology by : Giuseppe Giaccone

Download or read book Targeted Therapies in Oncology written by Giuseppe Giaccone and published by CRC Press. This book was released on 2013-10-21 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the last edition of this book, major advances have been made in our understanding of key pathways that control tumor progression. This has led to the development of new anticancer agents that have the ability to block the activity of proteins involved in neoplastic cell development and proliferation. Targeted Therapies in Oncology, Second Edi

Lung Cancer

Author : Kemp H. Kernstine, MD, PhD
Publisher : Demos Medical Publishing
ISBN 13 : 1617050180
Total Pages : 370 pages
Book Rating : 4.6/5 (17 download)

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Book Synopsis Lung Cancer by : Kemp H. Kernstine, MD, PhD

Download or read book Lung Cancer written by Kemp H. Kernstine, MD, PhD and published by Demos Medical Publishing. This book was released on 2010-10-25 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lung Cancer: Over the course of the last decade, the treatment of lung cancer has evolved quite rapidly. New scientific and clinical advances have modified the standard of care and led to improved patient outcomes. At the same time, the treatment of lung cancer has become increasingly complex, requiring the comprehensive review and assessment of multiple issues, genetics, radiology, surgery, reconstruction, chemotherapy, and more. As a result the harmony and open communication between these specialties facilitated by a multidisciplinary team approach are crucial in providing the best care to patients and ensuring successful treatment. Lung Cancer: A Multidisciplinary Approach to Diagnosis and Management, written by a multidisciplinary team of authors representing a range of disciplines, is a valuable resource for physicians, fellows, nurses, physician assistants, physical therapists, and all health care providers involved in the treatment of lung cancer. Lung Cancer: A Multidisciplinary Approach to Diagnosis and Management summarizes the state-of-the-art issues related to the treatment of lung cancer and describes an approach for optimal multidisciplinary care for individuals who have been diagnosed with lung cancer or who are at higher risk to develop lung cancer. About the Series: The Current Multidisciplinary Oncology series edited by Charles R. Thomas consolidates and integrates the varied aspects of multidisciplinary care for major topics in oncology, including breast, lung, prostrate, head and neck and more. The volumes in the Current Multidisciplinary Oncology series will represent all related topic areas, including oncology, radiation oncology, pain, pathology, imaging, psychological support and the primary disease. In addition, each volume includes a chapter focusing on special populations and the disease's impact / difference on them, and discussion of future directions and quality of life issues. In addition each volume has a chapter written by a private practice oncologist. All Current Multidisciplinary Oncology titles provide: Consolidation and integration of the varied aspects of multidisciplinary care for major topics in oncology Coverage of all related topic areas, including medical and surgical oncology, radiation oncology, pain, pathology, imaging, psychological support, and the primary disease A chapter focusing on special populations and the disease's impact / difference on them A chapter on community practice written by a private practice oncologist Discussion of quality-of-life issues

IASLC Thoracic Oncology E-Book

Author : Harvey Pass
Publisher : Elsevier Health Sciences
ISBN 13 : 0323527841
Total Pages : 904 pages
Book Rating : 4.3/5 (235 download)

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Book Synopsis IASLC Thoracic Oncology E-Book by : Harvey Pass

Download or read book IASLC Thoracic Oncology E-Book written by Harvey Pass and published by Elsevier Health Sciences. This book was released on 2017-04-21 with total page 904 pages. Available in PDF, EPUB and Kindle. Book excerpt: Global experts, in conjunction with the International Association for the Study of Lung Cancer, bring you up to date with today's best approaches to lung cancer diagnosis, treatment, and follow-up. IASLC Thoracic Oncology, 2nd Edition, keeps you abreast of the entire scope of this fast-changing field, from epidemiology to diagnosis to treatment to advocacy. Written in a straightforward, practical style for the busy clinician, this comprehensive, multidisciplinary title is a must-have for anyone involved in the care of patients with lung cancer and other thoracic malignancies. - Offers practical, relevant coverage of basic science, epidemiology, pulmonology, medical and radiation oncology, surgery, pathology, palliative care, nursing, and advocacy. - Provides authoritative guidance from the IASLC – the only global organization dedicated to the study of lung cancer. - Includes new content on molecular testing, immunotherapy, early detection, staging and the IASLC staging system, surgical resection for stage I and stage II lung cancer, and stem cells in lung cancer. - Features a new full-color design throughout, as well as updated diagnostic algorithms. - Expert ConsultTM eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, Q&As, and references from the book on a variety of devices.

Textbook of Uncommon Cancer

Author : Derek Raghavan
Publisher : John Wiley & Sons
ISBN 13 : 1119196205
Total Pages : 1296 pages
Book Rating : 4.1/5 (191 download)

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Book Synopsis Textbook of Uncommon Cancer by : Derek Raghavan

Download or read book Textbook of Uncommon Cancer written by Derek Raghavan and published by John Wiley & Sons. This book was released on 2017-05-08 with total page 1296 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fifth edition of the only comprehensive text dealing exclusively with rare or infrequently encountered malignancies in adults and children is an essential resource for any clinical oncologist. Encompasses all the information needed to diagnose and manage uncommon cancers, an area where advice and guidance is typically scarce Fully revised with new material and an evidence-based, teach-by-example approach Provides insight on real-world decision making in the clinical setting Edited and authored by a highly experienced and senior team of medical oncologists, radiation oncologists, and other specialists, giving a balanced and complete overview Extensively illustrated in full color throughout, including heat maps to show gene expression

Conn's Current Therapy 2010 E-Book

Author : Edward T. Bope
Publisher : Elsevier Health Sciences
ISBN 13 : 1437735517
Total Pages : 1343 pages
Book Rating : 4.4/5 (377 download)

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Book Synopsis Conn's Current Therapy 2010 E-Book by : Edward T. Bope

Download or read book Conn's Current Therapy 2010 E-Book written by Edward T. Bope and published by Elsevier Health Sciences. This book was released on 2010-01-08 with total page 1343 pages. Available in PDF, EPUB and Kindle. Book excerpt: Conn's Current Therapy 2010 provides concise and easy-to-use guidance on the latest advances in therapeutics for common complaints and diagnoses. Edward T. Bope, MD; Robert E. Rakel, MD; and Rick D. Kellerman offer their expertise and the knowledge of hundreds of skilled international leaders on the full range of evidence-based management options. Tap into recent developments and thorough updates on myelodysplastic syndromes, psychocutaneous medicine, recently-approved and soon-to-be-approved drugs, and much more to stay on top of current treatment practices. With the full text online at expertconsult.com, you'll have the information you need right at your fingertips for easy access! Provides access to the full contents of the text online at expertconsult.com. Discusses recent developments and thorough updates on myelodysplastic syndromes, psychocutaneous medicine, recently-approved and soon-to-be-approved drugs, and much so you can stay on top of current treatment practices. Contains important diagnostic criteria in each chapter because correct diagnoses lead to the delivery of effective treatment. Features acknowledged expert contributors for each chapter so you know that you are getting the best and most practical and accurate advice. Presents management methods used by international experts to provide you with best practices from around the world. Covers most common major presenting symptoms in a section on symptomatic care to assure that your patients can get the best possible treatment while tests are being performed. Incorporates the latest information on recently-approved and soon-to-be-approved drugs so you are aware of all treatment options. Includes the ICD-9 list of common diseases and codes on end papers to enable you and your staff to accurately code for reimbursement.

Biocomputing 2013 - Proceedings Of The Pacific Symposium

Author : Russ B Altman
Publisher : World Scientific
ISBN 13 : 9814447986
Total Pages : 472 pages
Book Rating : 4.8/5 (144 download)

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Book Synopsis Biocomputing 2013 - Proceedings Of The Pacific Symposium by : Russ B Altman

Download or read book Biocomputing 2013 - Proceedings Of The Pacific Symposium written by Russ B Altman and published by World Scientific. This book was released on 2012-11-16 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Pacific Symposium on Biocomputing (PSB) 2013 is an international, multidisciplinary conference for the presentation and discussion of current research in the theory and application of computational methods in problems of biological significance. Presentations are rigorously peer reviewed and are published in an archival proceedings volume. PSB 2013 will be held on January 3 - 7, 2013 in Kohala Coast, Hawaii. Tutorials and workshops will be offered prior to the start of the conference.PSB 2013 will bring together top researchers from the US, the Asian Pacific nations, and around the world to exchange research results and address open issues in all aspects of computational biology. It is a forum for the presentation of work in databases, algorithms, interfaces, visualization, modeling, and other computational methods, as applied to biological problems, with emphasis on applications in data-rich areas of molecular biology.The PSB has been designed to be responsive to the need for critical mass in sub-disciplines within biocomputing. For that reason, it is the only meeting whose sessions are defined dynamically each year in response to specific proposals. PSB sessions are organized by leaders of research in biocomputing's “hot topics.” In this way, the meeting provides an early forum for serious examination of emerging methods and approaches in this rapidly changing field.

Abeloff's Clinical Oncology E-Book

Author : John E. Niederhuber
Publisher : Elsevier Health Sciences
ISBN 13 : 1455728810
Total Pages : 2712 pages
Book Rating : 4.4/5 (557 download)

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Book Synopsis Abeloff's Clinical Oncology E-Book by : John E. Niederhuber

Download or read book Abeloff's Clinical Oncology E-Book written by John E. Niederhuber and published by Elsevier Health Sciences. This book was released on 2013-09-12 with total page 2712 pages. Available in PDF, EPUB and Kindle. Book excerpt: Practical and clinically focused, Abeloff’s Clinical Oncology is a trusted medical reference book designed to capture the latest scientific discoveries and their implications for cancer diagnosis and management of cancer in the most accessible manner possible. Abeloff’s equips everyone involved - from radiologists and oncologists to surgeons and nurses - to collaborate effectively and provide the best possible cancer care. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Select the most appropriate tests and imaging studies for cancer diagnosis and staging of each type of cancer, and manage your patients in the most effective way possible by using all of the latest techniques and approaches in oncology. Enhance your understanding of complex concepts with a color art program that highlights key points and illustrates relevant scientific and clinical problems. Stay at the forefront of the latest developments in cancer pharmacology, oncology and healthcare policy, survivorship in cancer, and many other timely topics. See how the most recent cancer research applies to practice through an increased emphasis on the relevance of new scientific discoveries and modalities within disease chapters. Streamline clinical decision making with abundant new treatment and diagnostic algorithms as well as concrete management recommendations. Take advantage of the collective wisdom of preeminent multidisciplinary experts in the field of oncology, including previous Abeloff’s editors John E. Niederhuber, James O. Armitage, and Michael B. Kastan as well as new editors James H. Doroshow from the National Cancer Institute and Joel E. Tepper of Gunderson & Tepper: Clinical Radiation Oncology. Quickly and effortlessly access the key information you need with the help of an even more user-friendly, streamlined format. Access the complete contents anytime, anywhere at Expert Consult, and test your mastery of the latest knowledge with 500 online multiple-choice review questions.

Novel Designs of Early Phase Trials for Cancer Therapeutics

Author : Shivaani Kummar
Publisher : Academic Press
ISBN 13 : 0128125705
Total Pages : 235 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Novel Designs of Early Phase Trials for Cancer Therapeutics by : Shivaani Kummar

Download or read book Novel Designs of Early Phase Trials for Cancer Therapeutics written by Shivaani Kummar and published by Academic Press. This book was released on 2018-05-22 with total page 235 pages. Available in PDF, EPUB and Kindle. Book excerpt: Novel Designs of Early Phase Trials for Cancer Therapeutics provides a comprehensive review by leaders in the field of the process of drug development, the integration of molecular profiling, the changes in early phase trial designs, and endpoints to optimally develop a new generation of cancer therapeutics. The book discusses topics such as statistical perspectives on cohort expansions, the role and application of molecular profiling and how to integrate biomarkers in early phase trials. Additionally, it discusses how to incorporate patient reported outcomes in phase one trials. This book is a valuable resource for medical oncologists, basic and translational biomedical scientists, and trainees in oncology and pharmacology who are interested in learning how to improve their research by using early phase trials. - Brings a comprehensive review and recommendations for new clinical trial designs for modern cancer therapeutics - Provides the reader with a better understanding on how to design and implement early phase oncology trials - Presents a better and updated understanding of the process of developing new treatments for cancer, the exciting scientific advances and how they are informing drug development

TMS 2017 146th Annual Meeting & Exhibition Supplemental Proceedings

Author : The Minerals, Metals & Materials Society TMS
Publisher : Springer
ISBN 13 : 3319514938
Total Pages : 777 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis TMS 2017 146th Annual Meeting & Exhibition Supplemental Proceedings by : The Minerals, Metals & Materials Society TMS

Download or read book TMS 2017 146th Annual Meeting & Exhibition Supplemental Proceedings written by The Minerals, Metals & Materials Society TMS and published by Springer. This book was released on 2017-02-18 with total page 777 pages. Available in PDF, EPUB and Kindle. Book excerpt: This collection features papers presented at the 146th Annual Meeting & Exhibition of The Minerals, Metals & Materials Society.

Reducing Environmental Cancer Risk

Author : Suzanne H. Reuben
Publisher : DIANE Publishing
ISBN 13 : 1437934218
Total Pages : 240 pages
Book Rating : 4.4/5 (379 download)

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Book Synopsis Reducing Environmental Cancer Risk by : Suzanne H. Reuben

Download or read book Reducing Environmental Cancer Risk written by Suzanne H. Reuben and published by DIANE Publishing. This book was released on 2010-10 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Though overall cancer incidence and mortality have continued to decline in recent years, cancer continues to devastate the lives of far too many Americans. In 2009 alone, 1.5 million American men, women, and children were diagnosed with cancer, and 562,000 died from the disease. There is a growing body of evidence linking environmental exposures to cancer. The Pres. Cancer Panel dedicated its 2008¿2009 activities to examining the impact of environmental factors on cancer risk. The Panel considered industrial, occupational, and agricultural exposures as well as exposures related to medical practice, military activities, modern lifestyles, and natural sources. This report presents the Panel¿s recommend. to mitigate or eliminate these barriers. Illus.

Cancer-Associated Thrombosis

Author : Alok A. Khorana
Publisher : CRC Press
ISBN 13 : 1420048007
Total Pages : 290 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Cancer-Associated Thrombosis by : Alok A. Khorana

Download or read book Cancer-Associated Thrombosis written by Alok A. Khorana and published by CRC Press. This book was released on 2007-09-26 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: Showcasing the expertise of top-tier specialists who contributed to the newly released guidelines for the care of thrombosis in cancer patients, this exciting guide was written and edited by members of the American Society of Clinical Oncology panel, (ASCO), on the prevention and treatment of cancer-associated thrombosis, among others, and provides

Update on the Treatment of Metastatic Non-small Cell Lung Cancer (NSCLC) in New Era of Personalised Medicine

Author : Vera Hirsh
Publisher : Frontiers Media SA
ISBN 13 : 2889453979
Total Pages : 95 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis Update on the Treatment of Metastatic Non-small Cell Lung Cancer (NSCLC) in New Era of Personalised Medicine by : Vera Hirsh

Download or read book Update on the Treatment of Metastatic Non-small Cell Lung Cancer (NSCLC) in New Era of Personalised Medicine written by Vera Hirsh and published by Frontiers Media SA. This book was released on 2018-01-24 with total page 95 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lung cancer remains a major cause of death in of both women and men in our society. Lung cancer treatment paradigms have changed enormously as we’ve started to understand the genetic complexity and the multiple driver mutations influencing the disease. Therapeutics directed towards, or to inhibit signaling pathways has resulted in increased life spans for our patients. Over the last two decades, we have gone from simple chemotherapy used to treat all, to a personalized medicine approach for the majority. For non-small cell lung cancer patients without driver mutations, the world of immune oncology has arrived. These improved long-term outcomes mean that now our lung cancer patients can live with their cancers, but without progression. The aim of this book is to catalogue the current state of knowledge for the many facets of advanced lung cancer. It describes current treatment approaches for driver mutations, rare mutations, and rare thoracic malignancies such as neuroendocrine tumors. Most importantly, this book addresses the topics of palliative treatment and care which allow our patients to enjoy longer survival with the highest quality of life. We hope you enjoy this e-book. The future is brighter for lung cancer patients and as lung cancer specialists; we finally feel sense optimism about treatment options for our patients.

Preoperative (Neoadjuvant) Chemotherapy

Author : Joseph Ragaz
Publisher : Springer Science & Business Media
ISBN 13 : 3642826717
Total Pages : 172 pages
Book Rating : 4.6/5 (428 download)

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Book Synopsis Preoperative (Neoadjuvant) Chemotherapy by : Joseph Ragaz

Download or read book Preoperative (Neoadjuvant) Chemotherapy written by Joseph Ragaz and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite recent advances in adjuvant therapies of cancer, the regi mens of postoperative adjuvant chemotherapy treatment which are presently available fail to cure the majority of cancer patients. Pre operative (neoadjuvant) chemotherapy represents a new approach in drug scheduling, based on sound theoretical, pharmacokinetic, and experimental principles. The preoperative timing of chemotherapy before definitive sur gery is not a minor change in the therapy of cancer. To be successful, large numbers of practitioners and their patients must participate. Substantial alterations of many aspects of the present management of cancer will have to follow. Therefore, before such therapy can be fully and routinely implemented, results of the novel treatment and its rationale have to be carefully evaluated. In preoperative treatment, other features will likely gain impor tance. For the first time, clinicians have a chance to follow the in vivo response of the tumor exposed to preoperative chemotherapy. The subsequent histological assessment of the tumor sample may likely become an important prognostic guide, permitting more re fined individual approaches to the planning of postoperative adju vant treatment. The value of such a treatment strategy can already be appreciated in the clinical setting, as seen from the therapy of osteosarcoma. Furthermore, preoperative chemotherapy might render previously inoperable tumors operable and hence resectable with a curative intention. The preoperative reduction of tumor bulk may also effectively decrease the need for more radical operations, permitting a more uniform adoption of conservative surgery.