Primary Afferent Plasticity Contributes To Emergence Of Bladder Dysfunction Following Spinal Cord Injury

Download Primary Afferent Plasticity Contributes To Emergence Of Bladder Dysfunction Following Spinal Cord Injury full books in PDF, epub, and Kindle. Read online Primary Afferent Plasticity Contributes To Emergence Of Bladder Dysfunction Following Spinal Cord Injury ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!

Plasticity of primary afferent neurons and sensory processing after spinal cord injury

Author : Alexander Rabchevsky
Publisher : Frontiers Media SA
ISBN 13 : 2889193969
Total Pages : 222 pages
Book Rating : 4.8/5 (891 download)

DOWNLOAD NOW!

Book Synopsis Plasticity of primary afferent neurons and sensory processing after spinal cord injury by : Alexander Rabchevsky

Download or read book Plasticity of primary afferent neurons and sensory processing after spinal cord injury written by Alexander Rabchevsky and published by Frontiers Media SA. This book was released on 2015-01-05 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traumatic injury of the spinal cord affects the entire organism directly and indirectly. Primary injury destroys neurons and severs axons which participate in neural circuits. Secondary injuries and pathologies arise from numerous sources including systemic inflammation, consequential damage of cutaneous, muscular, and visceral tissues, and dysregulation of autonomic, endocrine and sensory- motor functions. Evidence is mounting that spinal cord injury (SCI) affects regions of the nervous system spatially remote from the injury site, as well as peripheral tissues, and alters some basic characteristics of primary afferent cell biology and physiology (cell number, size/frequency, electrophysiology, other). The degree of afferent input and processing above the lesion is generally intact, while that in the peri-lesion area is highly variable, though pathologies emerge in both regions, including a variety of pain syndromes. Primary afferent input to spinal regions below the injury and the processing of this information becomes even more important in the face of complete or partial loss of descending input because such spared sensory processing can lead to both adaptive and pathological outcomes. This issue hosts review and research articles considering mechanisms of plasticity of primary afferent neurons and sensory processing after SCI, and how such plasticity contributes to sparing and/or recovery of functions, as well as exacerbation of existing and/or emergent pathologies. A critical issue for the majority of the SCI community is chronic above-, peri-, and below-level neuropathic pain, much of which may arise, at least in part, from plasticity of afferent fibers and nociceptive circuitry. For example, autonomic dysreflexia is common hypertensive syndrome that often develops after SCI that is highly reliant on maladaptive nociceptive sensory input and processing below the lesion. Moreover, the loss of descending input leaves the reflexive components of bladder/bowel/sexual function uncoordinated and susceptible to a variety of effects through afferent fiber plasticity. Finally, proper afferent feedback is vital for the effectiveness of activity-dependent rehabilitative therapies, but aberrant nociceptive input may interfere with these approaches since they are often unchecked due to loss of descending modulation.

Purinergic and Pyrimidinergic Signalling II

Author : Maria P. Abracchio
Publisher : Springer Science & Business Media
ISBN 13 : 3642569218
Total Pages : 459 pages
Book Rating : 4.6/5 (425 download)

DOWNLOAD NOW!

Book Synopsis Purinergic and Pyrimidinergic Signalling II by : Maria P. Abracchio

Download or read book Purinergic and Pyrimidinergic Signalling II written by Maria P. Abracchio and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 459 pages. Available in PDF, EPUB and Kindle. Book excerpt: Physiological, pharmacological and molecular biological data generated over the past three decades have demonstrated the existence of two major families of extracellular receptors, the P1, a family of four G-protein coupled receptors and the P2, a family of at least 12 receptors responsive to purine (ATP, ADP) and pyrimidine (UTP) nucleotides through which adenosine and ATP can function as extracellular messengers. The present two-part volume represents an integrated compendium of invited chapters by leading researchers in the area focusing on advances in the understanding of purinergic and pyrimidinergic signaling systems, their role(s) in tissue function and pathophysiology and advances in developing potential new medications based on the modulation of P1 and P2 receptor signaling processes. The volumes will thus provide the reader with a topical, comprehensive and integrated overview of this important area.

Autonomic Dysfunction After Spinal Cord Injury

Author : Lynne C. Weaver
Publisher : Elsevier
ISBN 13 : 0080460100
Total Pages : 472 pages
Book Rating : 4.0/5 (84 download)

DOWNLOAD NOW!

Book Synopsis Autonomic Dysfunction After Spinal Cord Injury by : Lynne C. Weaver

Download or read book Autonomic Dysfunction After Spinal Cord Injury written by Lynne C. Weaver and published by Elsevier. This book was released on 2005-10-11 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: Autonomic dysfunction is a major and poorly understood consequence of spinal cord injury. It is a cause of very serious disability and requires much more research. It should be a focus of treatment strategies. This book will be of interest to anyone involved in research and treatment of spinal cord injury since it helps to explain the tremendously negative impact on the body caused by cord injury that is not as obvious as paralysis and loss of sensation. It contains a compilation of what is known about bladder, cardiovascular, bowel and sexual dysfunction after spinal cord injury, as it relates to the changes within the autonomic nervous system control of these functions.The book begins with a description of the time course of autonomic dysfunctions and their ramifications from the first hours after a spinal cord injury to the more stable chronic states. The next section contains three chapters that address anatomical findings that may provide some of the foundation for autonomic dysfunctions in many of the systems. The system-specific chapters then follow in four sections. Each section begins with a chapter or two defining the clinical problems experienced by people with cord injury. The following chapters present research, basic and clinical, that address the autonomic dysfunctions.

Dissertation Abstracts International

Author :
Publisher :
ISBN 13 :
Total Pages : 886 pages
Book Rating : 4.F/5 ( download)

DOWNLOAD NOW!

Book Synopsis Dissertation Abstracts International by :

Download or read book Dissertation Abstracts International written by and published by . This book was released on 2008 with total page 886 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Neurourology

Author : Limin Liao
Publisher : Springer
ISBN 13 : 9401775095
Total Pages : 548 pages
Book Rating : 4.4/5 (17 download)

DOWNLOAD NOW!

Book Synopsis Neurourology by : Limin Liao

Download or read book Neurourology written by Limin Liao and published by Springer. This book was released on 2019-03-11 with total page 548 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book introduce neurourology as an emerging interdisciplinary area that covers the basic and clinical studies of the neural control on the normal lower urinary tract and the lower/upper urinary tract dysfunction due to neuropathy disorders. It systematically describes all aspects of neurourology from the epidemiology of the neurogenic bladder; to the pathology and pathophysiology of the lower urinary tract; to the diagnosis and treatment of the neurogenic bladder by conservative therapies or surgeries. This book provides a useful resource for medical doctors, nurses and students in the field of neurourological conditions. All the topics are written by internationally recognized specialists in their field.

Enteric Glia

Author : Brian D. Gulbransen
Publisher : Biota Publishing
ISBN 13 : 1615046615
Total Pages : 72 pages
Book Rating : 4.6/5 (15 download)

DOWNLOAD NOW!

Book Synopsis Enteric Glia by : Brian D. Gulbransen

Download or read book Enteric Glia written by Brian D. Gulbransen and published by Biota Publishing. This book was released on 2014-07-01 with total page 72 pages. Available in PDF, EPUB and Kindle. Book excerpt: The enteric nervous system (ENS) is a complex neural network embedded in the gut wall that orchestrates the reflex behaviors of the intestine. The ENS is often referred to as the “little brain” in the gut because the ENS is more similar in size, complexity and autonomy to the central nervous system (CNS) than other components of the autonomic nervous system. Like the brain, the ENS is composed of neurons that are surrounded by glial cells. Enteric glia are a unique type of peripheral glia that are similar to astrocytes of the CNS. Yet enteric glial cells also differ from astrocytes in many important ways. The roles of enteric glial cell populations in the gut are beginning to come to light and recent evidence implicates enteric glia in almost every aspect of gastrointestinal physiology and pathophysiology. However, elucidating the exact mechanisms by which enteric glia influence gastrointestinal physiology and identifying how those roles are altered during gastrointestinal pathophysiology remain areas of intense research. The purpose of this e-book is to provide an introduction to enteric glial cells and to act as a resource for ongoing studies on this fascinating population of glia. Table of Contents: Introduction / A Historical Perspective on Enteric Glia / Enteric Glia: The Astroglia of the Gut / Molecular Composition of Enteric Glia / Development of Enteric Glia / Functional Roles of Enteric Glia / Enteric Glia and Disease Processes in the Gut / Concluding Remarks / References / Author Biography

Canine Intervertebral Disc Disease: The Current State of Knowledge

Author : Natasha J. Olby
Publisher : Frontiers Media SA
ISBN 13 : 2889667405
Total Pages : 159 pages
Book Rating : 4.8/5 (896 download)

DOWNLOAD NOW!

Book Synopsis Canine Intervertebral Disc Disease: The Current State of Knowledge by : Natasha J. Olby

Download or read book Canine Intervertebral Disc Disease: The Current State of Knowledge written by Natasha J. Olby and published by Frontiers Media SA. This book was released on 2021-05-04 with total page 159 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Physiology of the Lower Urinary Tract

Author : Michael Torrens
Publisher : Springer Science & Business Media
ISBN 13 : 1447114493
Total Pages : 857 pages
Book Rating : 4.4/5 (471 download)

DOWNLOAD NOW!

Book Synopsis The Physiology of the Lower Urinary Tract by : Michael Torrens

Download or read book The Physiology of the Lower Urinary Tract written by Michael Torrens and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 857 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book we attempt a synthesis of knowledge from two investigative extremes. On the one hand, neurophysiology and neuropharmacology are progressing via the single neuron to a subcellular level; on the other, clinicians are studying the function ofthe human urinary system in vivo as a whole. A special effort must be made over the next decade to bridge this gap. We hope that the information summarized here will catalyse the process. In 1968, de Groat and Ryall published a group of papers in the Journal of Physiology in which modern quantitative electrophysiological techniques were applied to the study ofthe reflexes that regulate bladder Junction. These papers represent alandmark in the history of bladder neurophysiology, forming a dividing li ne between old and new. The earlier techniques of lesioning and stimulation of nervous structures yielded mainly qualitative information which was open to criticism because of lack of precise control over what was actually being destroyed or stimulated. Much of this earlier work was reviewed in an authoritative volume by Bors and Comarr in 1971, entitled Neurolqgical Urology. The 16 years have seen great advances in our understanding ofthe control oflower subsequent urinary tract function.

Traumatic Brain and Spinal Cord Injury

Author : Cristina Morganti-Kossmann
Publisher : Cambridge University Press
ISBN 13 : 1107007437
Total Pages : 361 pages
Book Rating : 4.1/5 (7 download)

DOWNLOAD NOW!

Book Synopsis Traumatic Brain and Spinal Cord Injury by : Cristina Morganti-Kossmann

Download or read book Traumatic Brain and Spinal Cord Injury written by Cristina Morganti-Kossmann and published by Cambridge University Press. This book was released on 2012-07-19 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents the most up-to-date clinical and experimental research in neurotrauma in an illustrated, accessible, comprehensive volume.

Multiple Sclerosis

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309072859
Total Pages : 457 pages
Book Rating : 4.3/5 (9 download)

DOWNLOAD NOW!

Book Synopsis Multiple Sclerosis by : Institute of Medicine

Download or read book Multiple Sclerosis written by Institute of Medicine and published by National Academies Press. This book was released on 2001-08-10 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multiple sclerosis is a chronic and often disabling disease of the nervous system, affecting about 1 million people worldwide. Even though it has been known for over a hundred years, no cause or cure has yet been discovered-but now there is hope. New therapies have been shown to slow the disease progress in some patients, and the pace of discoveries about the cellular machinery of the brain and spinal cord has accelerated. This book presents a comprehensive overview of multiple sclerosis today, as researchers seek to understand its processes, develop therapies that will slow or halt the disease and perhaps repair damage, offer relief for specific symptoms, and improve the abilities of MS patients to function in their daily lives. The panel reviews existing knowledge and identifies key research questions, focusing on: Research strategies that have the greatest potential to understand the biological mechanisms of recovery and to translate findings into specific strategies for therapy. How people adapt to MS and the research needed to improve the lives of people with MS. Management of disease symptoms (cognitive impairment, depression, spasticity, vision problems, and others). The committee also discusses ways to build and financially support the MS research enterprise, including a look at challenges inherent in designing clinical trials. This book will be important to MS researchers, research funders, health care advocates for MS research and treatment, and interested patients and their families.

Spinal Cord Injury

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309095859
Total Pages : 361 pages
Book Rating : 4.3/5 (9 download)

DOWNLOAD NOW!

Book Synopsis Spinal Cord Injury by : Institute of Medicine

Download or read book Spinal Cord Injury written by Institute of Medicine and published by National Academies Press. This book was released on 2005-08-27 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: An estimated 11,000 spinal cord injuries occur each year in the United States and more than 200,000 Americans suffer from maladies associated with spinal cord injury. This includes paralysis, bowel and bladder dysfunction, sexual dysfunction, respiratory impairment, temperature regulation problems, and chronic pain. During the last two decades, longstanding beliefs about the inability of the adult central nervous system to heal itself have been eroded by the flood of new information from research in the neurosciences and related fields. However, there are still no cures and the challenge of restoring function in the wake of spinal cord injuries remains extremely complex. Spinal Cord Injury examines the future directions for research with the goal to accelerate the development of cures for spinal cord injuries. While many of the recommendations are framed within the context of the specific needs articulated by the New York Spinal Cord Injury Research Board, the Institute of Medicine's panel of experts looked very broadly at research priorities relating to future directions for the field in general and make recommendations to strengthen and coordinate the existing infrastructure. Funders at federal and state agencies, academic organizations, pharmaceutical and device companies, and non-profit organizations will all find this book to be an essential resource as they examine their opportunities.

Locomotor Training

Author : Susan J. Harkema
Publisher :
ISBN 13 : 0195342089
Total Pages : 200 pages
Book Rating : 4.1/5 (953 download)

DOWNLOAD NOW!

Book Synopsis Locomotor Training by : Susan J. Harkema

Download or read book Locomotor Training written by Susan J. Harkema and published by . This book was released on 2011 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: Physical rehabilitation for walking recovery after spinal cord injury is undergoing a paradigm shift. Therapy historically has focused on compensation for sensorimotor deficits after SCI using wheelchairs and bracing to achieve mobility. With locomotor training, the aim is to promote recovery via activation of the neuromuscular system below the level of the lesion. What basic scientists have shown us as the potential of the nervous system for plasticity, to learn, even after injury is being translated into a rehabilitation strategy by taking advantage of the intrinsic biology of the central nervous system. While spinal cord injury from basic and clinical perspectives was the gateway for developing locomotor training, its application has been extended to other populations with neurologic dysfunction resulting in loss of walking or walking disability.

Spinal Cord Injury (SCI) Repair Strategies

Author : Giuseppe Perale
Publisher : Woodhead Publishing
ISBN 13 : 0081028083
Total Pages : 348 pages
Book Rating : 4.0/5 (81 download)

DOWNLOAD NOW!

Book Synopsis Spinal Cord Injury (SCI) Repair Strategies by : Giuseppe Perale

Download or read book Spinal Cord Injury (SCI) Repair Strategies written by Giuseppe Perale and published by Woodhead Publishing. This book was released on 2019-10-30 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Spinal Cord Injury (SCI) Repair Strategies provides researchers the latest information on potential regenerative approaches to spinal cord injury, specifically focusing on therapeutic approaches that target regeneration, including cell therapies, controlled drug delivery systems, and biomaterials. Dr. Giuseppe Perale and Dr. Filippo Rossi lead a team of authoritative authors in academia and industry in this innovative reference on the field of regenerative medicine and tissue engineering. This book presents all the information readers need to understand the current and potential array of techniques, materials, applications and their benefits for spinal cord repair. - Covers current and future repair strategies for spinal cord injury repair - Focuses on key research trends, clinics, biology and engineering - Provides fundamentals on regenerative engineering and tissue engineering

Spinal Cord Injury Pain

Author : International Association for the Study of Pain. Research Symposium
Publisher : Progress in Pain Research and
ISBN 13 :
Total Pages : 472 pages
Book Rating : 4.3/5 (91 download)

DOWNLOAD NOW!

Book Synopsis Spinal Cord Injury Pain by : International Association for the Study of Pain. Research Symposium

Download or read book Spinal Cord Injury Pain written by International Association for the Study of Pain. Research Symposium and published by Progress in Pain Research and. This book was released on 2002 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Propriospinal Neurons: Essential Elements in Locomotion, Autonomic Function and Plasticity after Spinal Cord Injury and Disease

Author : Katinka Stecina
Publisher : Frontiers Media SA
ISBN 13 : 2889669165
Total Pages : 177 pages
Book Rating : 4.8/5 (896 download)

DOWNLOAD NOW!

Book Synopsis Propriospinal Neurons: Essential Elements in Locomotion, Autonomic Function and Plasticity after Spinal Cord Injury and Disease by : Katinka Stecina

Download or read book Propriospinal Neurons: Essential Elements in Locomotion, Autonomic Function and Plasticity after Spinal Cord Injury and Disease written by Katinka Stecina and published by Frontiers Media SA. This book was released on 2021-06-28 with total page 177 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Autonomic Failure

Author : C. J. Mathias
Publisher : Oxford University Press, USA
ISBN 13 : 9780192628510
Total Pages : 562 pages
Book Rating : 4.6/5 (285 download)

DOWNLOAD NOW!

Book Synopsis Autonomic Failure by : C. J. Mathias

Download or read book Autonomic Failure written by C. J. Mathias and published by Oxford University Press, USA. This book was released on 1999 with total page 562 pages. Available in PDF, EPUB and Kindle. Book excerpt: This fourth edition of Autonomic Failure (now available in paperback) covers the many recent advances made in our understanding of the autonomic nervous system. There are 20 new chapters and extensive revisions of all other contributions. Autonomic failure, fourth edition makes diagnosis increasingly precise by fully evaluating the underlying anatomical and functional deficits, thereby allowing more effective treatment. This new edition continues to provide practitioners from a variety of fields, including neurology, cardiology, geriatric medicine, diabetology, and internal medicine, with a rational guide to aid in the recognition and management of autonomic disorders. The book starts with an updated classification of autonomic disorders and a history of the autonomic nervous system. The first two sections of the book deal with the fundamental aspects of autonomic structure, function, and integration. There are new chapters dealing with neurobiology, nerve growth factors, genetic mutations, neural and hormonal control of the cerebral circulation, innervation of the lung, and pathophysiological mechanisms causing nausea and vomiting. Advances in the clinical management of autonomic disorders are critically dependent on the bridge made between the basic and applied sciences.

Cajal's Degeneration and Regeneration of the Nervous System

Author : Santiago Ramón y Cajal
Publisher : History of Neuroscience
ISBN 13 : 0195065166
Total Pages : 977 pages
Book Rating : 4.1/5 (95 download)

DOWNLOAD NOW!

Book Synopsis Cajal's Degeneration and Regeneration of the Nervous System by : Santiago Ramón y Cajal

Download or read book Cajal's Degeneration and Regeneration of the Nervous System written by Santiago Ramón y Cajal and published by History of Neuroscience. This book was released on 1991 with total page 977 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a reprint of an English translation of Cajal's original work, with abundant notes and commentaries by the editor. This text describes Cajal's fundamental contributions to neuroscience, which continue to be important today. It accurately details Cajal's ideas and data, and providesreaders with the opportunity to learn what Cajal thought about his research career and the significance of his observations. Excerpts from Tello's memorial lectures also provide a contemporary view of Cajal's work.