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Prevention Of Alzheimers Disease From Cognitive Reserve To Precision Medicine
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Book Synopsis Prevention of Alzheimer’s Disease: From Cognitive Reserve to Precision Medicine by : Hyun Kook Lim
Download or read book Prevention of Alzheimer’s Disease: From Cognitive Reserve to Precision Medicine written by Hyun Kook Lim and published by Frontiers Media SA. This book was released on 2020-08-05 with total page 99 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Prevention of Alzheimer's Disease: From Cognitive Reserve to Precision Medicine by : Hyun Kook Lim
Download or read book Prevention of Alzheimer's Disease: From Cognitive Reserve to Precision Medicine written by Hyun Kook Lim and published by . This book was released on 2020 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Author :National Academies of Sciences, Engineering, and Medicine Publisher :National Academies Press ISBN 13 :0309459621 Total Pages :181 pages Book Rating :4.3/5 (94 download)
Book Synopsis Preventing Cognitive Decline and Dementia by : National Academies of Sciences, Engineering, and Medicine
Download or read book Preventing Cognitive Decline and Dementia written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-09-05 with total page 181 pages. Available in PDF, EPUB and Kindle. Book excerpt: Societies around the world are concerned about dementia and the other forms of cognitive impairment that affect many older adults. We now know that brain changes typically begin years before people show symptoms, which suggests a window of opportunity to prevent or delay the onset of these conditions. Emerging evidence that the prevalence of dementia is declining in high-income countries offers hope that public health interventions will be effective in preventing or delaying cognitive impairments. Until recently, the research and clinical communities have focused primarily on understanding and treating these conditions after they have developed. Thus, the evidence base on how to prevent or delay these conditions has been limited at best, despite the many claims of success made in popular media and advertising. Today, however, a growing body of prevention research is emerging. Preventing Cognitive Decline and Dementia: A Way Forward assesses the current state of knowledge on interventions to prevent cognitive decline and dementia, and informs future research in this area. This report provides recommendations of appropriate content for inclusion in public health messages from the National Institute on Aging.
Book Synopsis Handbook of Prevention and Alzheimer’s Disease by : C.A. Raji
Download or read book Handbook of Prevention and Alzheimer’s Disease written by C.A. Raji and published by IOS Press. This book was released on 2024-02-20 with total page 674 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is almost 120 years since Alzheimer’s disease (AD) was first reported, and the concept of modifiable risk factors associated with the disease has been present from the outset. Thus, the idea of preventing AD is not new, with reference to strategies noted as early as the 1990s. This subfield of AD research has matured in recent years, with the number of modifiable risk factors – the AD preventome – rising from the 7 initially identified to the current 12, with an estimated contribution to dementia cases worldwide of about 40%. This book, the Handbook of Prevention and Alzheimer’s Disease, introduces physicians, scientists, and other stakeholders to this subfield of AD research. It investigates the AD preventome, which will continue to expand as the understanding of new factors and related biomarkers is refined. Optimizing this preventome leads to an improvement in overall brain health, an outcome which reduces the risk of developing AD and improves quality of life. The book goes on to examine other domains of prevention, from vascular risk factors to social engagement and from sleep health to spirituality. If the journey to end AD can be likened to a long and arduous challenge, understanding every possible part of the overall toolkit of approaches for disease prevention and intervention is essential. Together with its companion volume on intervention, the book provides a comprehensive overview of strategies for tackling Alzheimer’s disease, and will be of interest to all those working in the field. Cover illustration: White matter tracts showing sex differences in connectivity in men versus women as a function of increasing body mass index. Reprinted with permission from Rahmani F, Wang Q, McKay NS, Keefe S, Hantler N, Hornbeck R, Wang Y, Hassenstab J, Schindler S, Xiong C, Morris JC, Benzinger TLS, Raji CA. Sex-Specific Patterns of Body Mass Index Relationship with White Matter Connectivity. J Alzheimers Dis. 2022;86(4):1831-1848. doi: 10.3233/JAD-215329. PMID: 35180116; PMCID: PMC9108572.
Book Synopsis Handbook of Intervention and Alzheimer’s Disease by : C.A. Raji
Download or read book Handbook of Intervention and Alzheimer’s Disease written by C.A. Raji and published by IOS Press. This book was released on 2024-02-22 with total page 768 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is almost 120 years since Alzheimer’s disease (AD) was first reported, and the concept of managing some of the modifiable risk factors associated with the disease has been present from the outset. Intervening to manage risk factors as a way of tackling AD is not new, but optimizing brain health as a way of minimizing risk and maximizing the potential benefits of revolutionary new treatments for AD is becoming increasingly important. This book, the Handbook of Intervention and Alzheimer’s Disease, presents 47 papers exploring factors which may either inspire or inform future treatment and clinical trials. While novel interventions such as anti-amyloid immunotherapy present great opportunities, they may also increase the risk of brain bleeds and edema, which in turn may lead to adverse clinical outcomes. Such adverse outcomes are demonstrably more likely to occur in persons with poor brain health, so improved management of the risk factors which make up the AD preventome will also minimize the risks associated with such novel therapies. The papers in this volume can therefore be thought of as offering insight into those factors that can optimize brain health or providing key insights into interventions which may achieve such outcomes. Together with its companion volume on prevention, the book provides a comprehensive overview of strategies for tackling Alzheimer’s disease, and will be of interest to all those working in the field. Cover illustration: Improved hypoperfusion (resolving blue colors) on ASL MRI Z-score maps superimposed on structural MRI scans at baseline and one year in a PET amyloid-positive research participant with cognitive complaints undergoing one year of multi-domain personalized brain health interventions (vascular disease management, dietary optimization, sustained physical activity etc.). Permission to use this figure was granted both by the study P.I. Dr. David Merrill, MD, PhD, of the Pacific Neuroscience Institute and the research participant.
Book Synopsis Alzheimer’s Turning Point by : Jack C. de la Torre
Download or read book Alzheimer’s Turning Point written by Jack C. de la Torre and published by Springer. This book was released on 2016-06-25 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: This compelling text provides an overview of the available technology for early detection and therapeutic management of vascular risk factors to Alzheimer’s before severe cognitive impairment symptoms appear. Chapters bring the reader from the trackless clinical research that has characterized Alzheimer’s progress for the last 20 years, to a nexus of new ideas and concepts that can change our outlook of this dementia. In-depth examinations of various hypotheses, preventive measures, current and prospective treatments are openly and clearly explored. The author discusses in depth his proposal of the vascular hypothesis of Alzheimer's disease which has become a mother-lode for basic and clinical studies and a key approach to the prevention of this dementia.Alzheimer’s Turning Point offers professionals, students and those looking to learn more about this disorder a fresh clinical perspective of this devastating disease.
Book Synopsis The Alzheimer's Prevention and Treatment Diet by : Richard S. Isaacson, MD
Download or read book The Alzheimer's Prevention and Treatment Diet written by Richard S. Isaacson, MD and published by Square One Publishers, Inc.. This book was released on 2016-05-19 with total page 251 pages. Available in PDF, EPUB and Kindle. Book excerpt: *** OVER 13,000 COPIES SOLD *** SEEN NATIONWIDE ON THE DR. OZ SHOW Increasingly, research has shown that diet is one of the greatest weapons we have to protect and defend your rain against Alzheimer’s disease (AD). Based on current studies as well as firsthand experience working with thousands of patients—both those who have normal cognitive health and those in the early stages of Alzheimer’s—The Alzheimer’s Prevention & Treatment Diet provides a cutting-edge nutritional program that can help reduce the risk for AD and may slow its progress if it has already developed. This book: * Presents a nine-week diet plan that gradually introduces brain-healthy foods and dietary strategies. * Guides you in making smart lifestyle choices, from exercise to hobbies, that strengthen cognitive health. * Explores nutritional supplements that can support the brain and prevent cognitive decline. * Offers suggestions for managing the special nutritional needs of loved ones with AD. * Explains the medications used to treat AD—what they are, what they do, and how they should be used. * Provides sample full-day menus, including breakfast, lunch, dinner, and snacks. * Presents lists of recommended foods to make meal planning easy. Whatever your age, now is the perfect time to start adopting a brain-healthy lifestyle. The Alzheimer’s Prevention and Treatment Diet guides you in making changes that can significantly enhance your cognitive well-being—now and for a lifetime.
Book Synopsis How to Prevent Dementia by : Richard Restak
Download or read book How to Prevent Dementia written by Richard Restak and published by Simon and Schuster. This book was released on 2023-10-17 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive guide to preventing Alzheimer’s and other thinking disorders from bestselling author and renowned authority Dr. Richard Restak! How to Prevent Dementia begins with the principle that the more we know about dementia, the easier it is to prevent or delay it. A better foundation of knowledge also helps people to understand and interact thoughtfully with family members and other loved ones who may have Alzheimer’s and other dementias. Dr. Restak examines the basic thinking of normal everyday people and progresses to people with thinking disorders. In understanding that dementias exist along a continuum, starting with perfectly normal performance and ending at the extremes of mental dysfunction, we learn how our attention to everyday habits, choices, and behaviors can affect where we are located along that continuum, as well as whether or how we will progress from one part to another. As can be gleaned from recent reports, researchers may be on the cusp of a meaningful treatment or cure for Alzheimer’s. Dr. Restak also helps the reader to grasp both the positive and challenging consequences of the new medications that will soon be available. At the end of the book, the reader will understand what practical steps can be taken each day to lessen the odds of dementia and how to take advantage of new medications, while gaining a better understanding of thinking and what it is like to have it falter.
Book Synopsis The Alzheimer's Solution by : Dean Sherzai
Download or read book The Alzheimer's Solution written by Dean Sherzai and published by HarperOne. This book was released on 2019-01-29 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: A revolutionary, proven program for reversing the symptoms of Alzheimer's disease and cognitive decline from award winning neurologists and codirectors of the Brain Health and Alzheimer's Prevention Program at Loma Linda University Medical Center Over 47 million people are currently living with Alzheimer’s disease worldwide. While all other major diseases are in decline, deaths from Alzheimer’s have increased radically. What you or your loved ones don’t yet know is that 90 percent of Alzheimer’s cases can be prevented. Based on the largest clinical and observational study to date, neurologists and codirectors of the Brain Health and Alzheimer’s Prevention Program at Loma Linda University Medical Center, Drs. Dean and Ayesha Sherzai, offer in The Alzheimer’s Solution the first comprehensive program for preventing Alzheimer’s disease and improving cognitive function. Alzheimer’s disease isn’t a genetic inevitability, and a diagnosis does not need to come with a death sentence. Ninety percent of grandparents, parents, husbands, and wives can be spared. Ninety percent of us can avoid ever getting Alzheimer’s, and for the 10 percent with strong genetic risk for cognitive decline, the disease can be delayed by ten to fifteen years. This isn’t an estimate or wishful thinking; it’s a percentage based on rigorous science and the remarkable results the Sherzais have seen firsthand in their clinic. This much-needed revolutionary book reveals how the brain is a living universe, directly influenced by nutrition, exercise, stress, sleep, and engagement. In other words: what you feed it, how you treat it, when you challenge it, and the ways in which you allow it to rest. These factors are the pillars of the groundbreaking program you’ll find in these pages, which features a personalized assessment for evaluating risk, a five-part program for prevention and symptom-reversal, and day-by-day guides for optimizing cognitive function. You can prevent Alzheimer’s disease from affecting you, your family, friends, and loved ones. Even with a diagnosis, you can reverse cognitive decline and add vibrant years to your life. The future of your brain is finally within your control.
Book Synopsis The End of Alzheimer's by : Dale Bredesen
Download or read book The End of Alzheimer's written by Dale Bredesen and published by Penguin. This book was released on 2017-08-22 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: The instant New York Times and Wall Street Journal bestseller A groundbreaking plan to prevent and reverse Alzheimer’s Disease that fundamentally changes how we understand cognitive decline. Everyone knows someone who has survived cancer, but until now no one knows anyone who has survived Alzheimer's Disease. In this paradigm shifting book, Dale Bredesen, MD, offers real hope to anyone looking to prevent and even reverse Alzheimer's Disease and cognitive decline. Revealing that AD is not one condition, as it is currently treated, but three, The End of Alzheimer’s outlines 36 metabolic factors (micronutrients, hormone levels, sleep) that can trigger "downsizing" in the brain. The protocol shows us how to rebalance these factors using lifestyle modifications like taking B12, eliminating gluten, or improving oral hygiene. The results are impressive. Of the first ten patients on the protocol, nine displayed significant improvement with 3-6 months; since then the protocol has yielded similar results with hundreds more. Now, The End of Alzheimer’s brings new hope to a broad audience of patients, caregivers, physicians, and treatment centers with a fascinating look inside the science and a complete step-by-step plan that fundamentally changes how we treat and even think about AD.
Book Synopsis 100 Simple Things You Can Do to Prevent Alzheimer's and Age-Related Memory Loss by : Jean Carper
Download or read book 100 Simple Things You Can Do to Prevent Alzheimer's and Age-Related Memory Loss written by Jean Carper and published by Hachette+ORM. This book was released on 2010-09-20 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most people think there is little or nothing you can do to avoid Alzheimer's. But scientists know this is no longer true. In fact, prominent researchers now say that our best and perhaps only hope of defeating Alzheimer's is to prevent it. After best-selling author Jean Carper discovered that she had the major susceptibility gene for Alzheimer's, she was determined to find all the latest scientific evidence on how to escape it. She discovered 100 surprisingly simple scientifically tested ways to radically cut the odds of Alzheimer's, memory decline, and other forms of dementia. Did you know that vitamin B 12 helps keep your brain from shrinking? Apple juice mimics a common Alzheimer's drug? Surfing the internet strengthens aging brain cells? Ordinary infections and a popular anesthesia may trigger dementia? Meditating spurs the growth of new neurons? Exercise is like Miracle-Gro for your brain? Even a few preventive actions could dramatically change your future by postponing Alzheimer's so long that you eventually outlive it. If you can delay the onset of Alzheimer's for five years, you cut your odds of having it by half. Postpone Alzheimer's for ten years, and you'll most likely never live to see it. 100 Simple Things You Can Do to Prevent Alzheimer's will change the way you look at Alzheimer's and provide exciting new answers from the frontiers of brain research to help keep you and your family free of this heartbreaking disease.
Book Synopsis Alzheimer's Disease by : Jolanta Dorszewska
Download or read book Alzheimer's Disease written by Jolanta Dorszewska and published by BoD – Books on Demand. This book was released on 2018-07-18 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alzheimer's disease was discovered over 100 years ago and still belongs to incurable neurological diseases; its pharmacotherapy is considered to be ineffective. This book presents contemporary views on the genetic, biochemical, and immunological determinants of this disease. This book also concerns the issue of Alzheimer's disease prevention through lifestyle and physical activity. Moreover, it describes the therapies used in Alzheimer's disease to slow the progression of the disease and delay its onset. Subsequently, the authors discuss experimental and clinical trials used now and in the near future. We hope that this book will help the readers to understand the complex mechanism leading to the development of Alzheimer's disease and indicate effective ways to prevent this disorder.
Download or read book GeNeDis 2020 written by Panayiotis Vlamos and published by Springer Nature. This book was released on 2022-01-01 with total page 391 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 4th World Congress on Genetics, Geriatrics and Neurodegenerative Diseases Research (GeNeDis 2020) focuses on the latest major challenges in scientific research, new drug targets, the development of novel biomarkers, new imaging techniques, novel protocols for early diagnosis of neurodegenerative diseases, and several other scientific advances, with the aim of better, safer, and healthier aging. The increase in the average length of life leads to the development of various diseases in the elderly population. This volume focuses on the sessions from the conference on Geriatrics.
Book Synopsis Healthy Brain Aging: Evidence Based Methods to Preserve Brain Function and Prevent Dementia, An issue of Clinics in Geriatric Medicine by : Abhilash K. Desai
Download or read book Healthy Brain Aging: Evidence Based Methods to Preserve Brain Function and Prevent Dementia, An issue of Clinics in Geriatric Medicine written by Abhilash K. Desai and published by Elsevier Health Sciences. This book was released on 2010-03-17 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue examines what is a healthy aging brain and covers preventive measures for succesful cognitive aging. Topics covered include: A road map to healthy aging brain; Cardiovascular risk factors, cerebrovascular disease burden and healthy aging brain; Healthy aging brain: Impact of head injury, alcohol and environmental toxins; Healthy aging brain: What has sleep go to do with it?; Endocrine aspects of healthy aging brain; Healthy aging brain: Role of exercise and physically active lifestyle; Healthy aging brain: Role of nutrition and nutritional supplements; Healthy aging brain: Role of cognitive reserve, cognitive stimulation and cognitive exercises; Healthy aging brain: Impact of positive and negative emotions; Dementia risk predictor. Are we there yet?; Potential future neuroprotective therapies for neurodegenerative disorders and stroke; Healthy aging brain: Importance of promoting resilience and creativity.
Book Synopsis Preventing Alzheimer's Disease by : Yoram Barak
Download or read book Preventing Alzheimer's Disease written by Yoram Barak and published by Nova Science Publishers. This book was released on 2014-02-03 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The prevention of dementia, and particularly of Alzheimer's disease, is a major challenge for researchers and clinicians. In this book, the mixture of evidence, observations and hypotheses in the current literature is categorized into avenues for possible preventive interventions, as suggested by the NIH State-of-the-Science Conference. The main categories are: antihypertensive medications; nutrition; cognitive engagement; volunteering and physical activity. There is, as yet, no conclusive evidence, but each category may hold promise for the prevention of dementia. The robust findings are as follows: cognitive engagement and regular physical activity may reduce the risk of Alzheimer's disease; the Mediterranean diet and consumption of omega-3 fatty acids deserves further elucidation; and the meticulous management of risk factors, and especially hypertension, is the infrastructure of Alzheimer's disease prevention. Combating loneliness and volunteering both contribute to reducing the risk of dementia.
Book Synopsis Sex and Gender Differences in Alzheimer's Disease by : Maria Teresa Ferretti
Download or read book Sex and Gender Differences in Alzheimer's Disease written by Maria Teresa Ferretti and published by Academic Press. This book was released on 2021-07-23 with total page 514 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sex and Gender Differences in Alzheimer’s Disease: The Women’s Brain Project offers for the first time a critical overview of the evidence documenting sex and gender differences in Alzheimer’s disease neurobiology, biomarkers, clinical presentation, treatment, clinical trials and their outcomes, and socioeconomic impact on both patients and caregivers. This knowledge is crucial for clinical development, digital health solutions, as well as social and psychological support to Alzheimer’s disease families, in the frame of a precision medicine approach to Alzheimer’s disease.This book brings together up-to-date findings from a variety of experts, covering basic neuroscience, epidemiology, diagnosis, treatment, clinical trials development, socioeconomic factors, and psychosocial support. Alzheimer’s disease, the most common form of dementia, remains an unmet medical need for the planet. Wide interpersonal variability in disease onset, presentation, and biomarker profile make Alzheimer’s a clinical challenge to neuroscientists, clinicians, and drug developers alike, resulting in huge management costs for health systems and society. Not only do women represent the majority of Alzheimer’s disease patients, but they also represent two-thirds of caregivers. Understanding sex and gender differences in Alzheimer’s disease will lead to novel insights into disease mechanisms, and will be crucial for personalized disease management strategies and solutions, involving both the patient and their family. Endorsements/Reviews: "There is a clear sex and gender gap in outcomes for brain health disorders like Alzheimer’s disease, with strikingly negative outcomes for women. This understanding calls for a more systematic way of approaching this issue of inequality. This book effectively highlights and frames inequalities in all areas across the translational spectrum from bench-to-bedside and from boardroom-to-policy and economics. Closing the Brain Health Gap will help economies create recovery and prepare our systems for future global shocks." Harris A. Eyre MBBS, PhD, co-lead, Neuroscience-inspired Policy Initiative, OECD and PRODEO Institute. Instructor in Brain Health Diplomacy, Global Brain Health Institute, UCSF and TCD. "Sex and Gender Differences in Alzheimer's disease is the most important title to emerge on Alzheimer's disease in recent years.This comprehensive, multidisciplinary book is a must read for anyone with a serious interest in dementia prevention, diagnosis, treatment, care, cure and research. Precision medicine is the future of healthcare and this book represents an incredible and necessary resource to guide practice, policy and research in light of the fact that Alzheimer's disease disproportionately affects women. The combination of contributions from the most eminent experts and the most up-to-date research makes this an invaluable resource for clinicians, care providers, academics, researchers and policy makers. Given the complex nature of dementia and the multiple factors that influence risk and disease trajectory the scope of the book is both impressive and important covering sex differences in neurobiological processes, sex and gender differences in clinical aspects and gender differences linked to socioeconomic factors relevant to Alzheimer's disease. If you work in Alzheimer's disease, or indeed other dementias, then Sex and Gender Differences in Alzheimer's disease is a must have for your bookshelf." -- Sabina Brennan, PhD., C.Psychol.,PsSI., National representative for Ireland on Alzheimer Disease International's Medical and Scientific Advisory Panel
Author :National Academies of Sciences Engineering and Medicine Publisher : ISBN 13 :9780309495035 Total Pages : pages Book Rating :4.4/5 (95 download)
Book Synopsis Reducing the Impact of Dementia in America by : National Academies of Sciences Engineering and Medicine
Download or read book Reducing the Impact of Dementia in America written by National Academies of Sciences Engineering and Medicine and published by . This book was released on 2022-04-26 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: As the largest generation in U.S. history - the population born in the two decades immediately following World War II - enters the age of risk for cognitive impairment, growing numbers of people will experience dementia (including Alzheimer's disease and related dementias). By one estimate, nearly 14 million people in the United States will be living with dementia by 2060. Like other hardships, the experience of living with dementia can bring unexpected moments of intimacy, growth, and compassion, but these diseases also affect people's capacity to work and carry out other activities and alter their relationships with loved ones, friends, and coworkers. Those who live with and care for individuals experiencing these diseases face challenges that include physical and emotional stress, difficult changes and losses in their relationships with life partners, loss of income, and interrupted connections to other activities and friends. From a societal perspective, these diseases place substantial demands on communities and on the institutions and government entities that support people living with dementia and their families, including the health care system, the providers of direct care, and others. Nevertheless, research in the social and behavioral sciences points to possibilities for preventing or slowing the development of dementia and for substantially reducing its social and economic impacts. At the request of the National Institute on Aging of the U.S. Department of Health and Human Services, Reducing the Impact of Dementia in America assesses the contributions of research in the social and behavioral sciences and identifies a research agenda for the coming decade. This report offers a blueprint for the next decade of behavioral and social science research to reduce the negative impact of dementia for America's diverse population. Reducing the Impact of Dementia in America calls for research that addresses the causes and solutions for disparities in both developing dementia and receiving adequate treatment and support. It calls for research that sets goals meaningful not just for scientists but for people living with dementia and those who support them as well. By 2030, an estimated 8.5 million Americans will have Alzheimer's disease and many more will have other forms of dementia. Through identifying priorities social and behavioral science research and recommending ways in which they can be pursued in a coordinated fashion, Reducing the Impact of Dementia in America will help produce research that improves the lives of all those affected by dementia.
