Predictive Preventive And Personalised Medicine From Bench To Bedside

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Predictive, Preventive, and Personalised Medicine: From Bench to Bedside

Author : Halina Podbielska
Publisher : Springer Nature
ISBN 13 : 3031348842
Total Pages : 352 pages
Book Rating : 4.0/5 (313 download)

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Book Synopsis Predictive, Preventive, and Personalised Medicine: From Bench to Bedside by : Halina Podbielska

Download or read book Predictive, Preventive, and Personalised Medicine: From Bench to Bedside written by Halina Podbielska and published by Springer Nature. This book was released on 2023-12-01 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume presents advanced bio/medical sciences with a particular value for translating research achievements into daily medical practice in the framework of Predictive, Preventive and Personalised Medicine (3PM/PPPM). First two decades of the 21st century are characterised by epidemics of non-communicable diseases such as many hundreds of millions of patients diagnosed with cardiovascular diseases and the type 2 diabetes mellitus, breast, lung, liver and prostate malignancies, neurological, sleep, mood and eye disorders, amongst others. Consequent socio-economic burden is tremendous. Unprecedented decrease in age of maladaptive individuals has been reported. The absolute majority of expanding non-communicable disorders carry a chronic character, over a couple of years progressing from reversible suboptimal health conditions to irreversible severe pathologies and cascading collateral complications. The paradigm change from reactive to predictive preventive and personalised medicine is essential to promote population health by application of individualised patient profiling, multi-parametric analysis leading to cost-effective targeted prevention. To this end, inadequate data for risk assessment on speed and urgency of COVID-19, combined with increased globalization of human society, led to the rapid spread of COVID-19. Despite an abundance of digital methods that could be used in slowing or stopping this virus and future pandemics, the world remains unprepared, and lessons have not been learned from previous cases of pandemics. The book presents PPPM strategies which might be of great clinical utility for future pandemics. In a long-term way, a significantly improved healthcare economy is one of the clear benefits of the proposed paradigm shift; a tight collaboration between all stakeholders including scientific community, healthcare providers, patient organisations, policy-makers and educators is analysed for the smooth implementation of the 3PM concepts. Further issues linked to big data management and medical ethics have to be carefully treated in the context of application of artificial intelligence in medicine.

An Information Technology Framework for Predictive, Preventive and Personalised Medicine

Author : Leonard Berliner
Publisher :
ISBN 13 : 9783319121673
Total Pages : pages
Book Rating : 4.1/5 (216 download)

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Book Synopsis An Information Technology Framework for Predictive, Preventive and Personalised Medicine by : Leonard Berliner

Download or read book An Information Technology Framework for Predictive, Preventive and Personalised Medicine written by Leonard Berliner and published by . This book was released on 2015 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores how PPPM, clinical practice, and basic research could be best served by information technology (IT). A use-case was developed for hepatocellular carcinoma (HCC). The subject was approached with four interrelated tasks: (1) review of clinical practices relating to HCC; (2) propose an IT system relating to HCC, including clinical decision support and research needs; (3) determine how a clinical liver cancer center can contribute; and, (4) examine the enhancements and impact that the first three tasks will have on the management of HCC. An IT System for Personalized Medicine (ITS-PM) for HCC will provide the means to identify and determine the relative value of the wide number of variables, including clinical assessment of the patient -- functional status, liver function, degree of cirrhosis, and comorbidities; tumor biology, at a molecular, genetic and anatomic level; tumor burden and individual patient response; medical and operative treatments and their outcomes.

Digital Health Approach for Predictive, Preventive, Personalised and Participatory Medicine

Author : Lotfi Chaari
Publisher : Springer
ISBN 13 : 3030118002
Total Pages : 88 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Digital Health Approach for Predictive, Preventive, Personalised and Participatory Medicine by : Lotfi Chaari

Download or read book Digital Health Approach for Predictive, Preventive, Personalised and Participatory Medicine written by Lotfi Chaari and published by Springer. This book was released on 2019-07-10 with total page 88 pages. Available in PDF, EPUB and Kindle. Book excerpt: This collection, entitled Digital Health for Predictive, Preventive, Personalized and Participatory Medicine contains the proceedings of the first International conference on digital healthtechnologies (ICDHT 2018). Ten recent contributions in the fields of Artificial Intelligence (AI) and machine learning, Internet of Things (IoT) and data analysis, all applied to digital health. This collection enables researchers to learn about recent advances in the above mentioned fields. It brings a technological viewpoint of P4 medicine. Readers will discover how advanced Information Technology (IT) tools can be used for healthcare. For instance, the use of connected objects to monitor physiological parameters is discussed. Moreover, even if compressed sensing is nowadays a common acquisition technique, its use for IoT is presented in this collection through one of the pioneer works in the field. In addition, the use of AI for epileptic seizure detection is also discussed as being one of the major concerns of predictive medicine both in industrialized and low-income countries. This work is edited by Prof. Lotfi Chaari, professor at the University of Sfax, and previously at the University of Toulouse. This work comes after more than ten years of expertise in the biomedical signal and image processing field.

Personalised Health Care

Author : Stefania Boccia
Publisher : Springer Nature
ISBN 13 : 3030523993
Total Pages : 135 pages
Book Rating : 4.0/5 (35 download)

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Book Synopsis Personalised Health Care by : Stefania Boccia

Download or read book Personalised Health Care written by Stefania Boccia and published by Springer Nature. This book was released on 2020-11-23 with total page 135 pages. Available in PDF, EPUB and Kindle. Book excerpt: Practitioners are increasingly adopting a personalised medicine approach to individually tailored patient care, especially disease diagnosis and treatment with the use of biomarkers. However, development and implementation of such approaches to chronic disease prevention need further investigation and concerted efforts for proper use in healthcare systems. This book provides high-quality, multidisciplinary knowledge from research in personalised medicine, specifically personalised prevention of chronic disease. It addresses different perspectives of prevention in the field, and is the outcome of a four-year work of the Personalized prevention of Chronic Disease (PRECeDI) Consortium, a multi-disciplinary and multi-professional team of experts. The Consortium jointly agreed to document and address the five aspects or domains of personalised medicine and prevention as individual chapters: Identification of biomarkers for the prevention of chronic disease Evaluation of predictive genomic applications Ethico-legal and policy issues surrounding personalised medicine Roles and responsibilities of stakeholders in informing healthy individuals on their genome: a sociotechnical analysis Identification of organisational models for the provision of predictive genomic applications The book focuses on the Consortium's recommendations that are derived from each of these domains based on up-to-date evidence and research that the authors write, follow, and systematically organise and report. Personalisation of health care is, eventually, a driver of innovation in research and healthcare systems. With this SpringerBrief on Personalised Health Care: Fostering Precision Medicine Advancements for Gaining Population Health Impact, the Consortium provides further evidence of the clinical validity and utility of personalised medicine with special emphasis on the prevention of chronic diseases. The book is a useful resource for policy makers, industry and healthcare professionals, scientists, technology-sector professionals, investors, citizens, and private companies that need proper advice to realise the potential of personalised medicine.

Digital Health Approach for Predictive, Preventive, Personalised and Participatory Medicine

Author :
Publisher :
ISBN 13 : 9783030118013
Total Pages : 99 pages
Book Rating : 4.1/5 (18 download)

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Book Synopsis Digital Health Approach for Predictive, Preventive, Personalised and Participatory Medicine by :

Download or read book Digital Health Approach for Predictive, Preventive, Personalised and Participatory Medicine written by and published by . This book was released on 2019 with total page 99 pages. Available in PDF, EPUB and Kindle. Book excerpt: This collection, entitled #x1B;(S0#x1B;(B Digital Health for Predictive, Preventive, Personalized and Participatory Medicine#x1B;(S1#x1B;(B contains the proceedings of the first International conference on digital health technologies (ICDHT 2018). Ten recent contributions in the fields of Artificial Intelligence (AI) and machine learning, Internet of Things (IoT) and data analysis, all applied to digital health. This collection enables researchers to learn about recent advances in the above mentioned fields. It brings a technological viewpoint of P4 medicine. Readers will discover how advanced Information Technology (IT) tools can be used for healthcare. For instance, the use of connected objects to monitor physiological parameters is discussed. Moreover, even if compressed sensing is nowadays a common acquisition technique, its use for IoT is presented in this collection through one of the pioneer works in the field. In addition, the use of AI for epileptic seizure detection is also discussed as being one of the major concerns of predictive medicine both in industrialized and low-income countries. This work is edited by Prof. Lotfi Chaari, professor at the University of Sfax, and previously at the University of Toulouse. This work comes after more than ten years of expertise in the biomedical signal and image processing field.

Advances in predictive, preventive and personalised medicine

Author : [Anonymus AC10761770]
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (98 download)

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Book Synopsis Advances in predictive, preventive and personalised medicine by : [Anonymus AC10761770]

Download or read book Advances in predictive, preventive and personalised medicine written by [Anonymus AC10761770] and published by . This book was released on 2012 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Digital Health in Focus of Predictive, Preventive and Personalised Medicine

Author : Lotfi Chaari
Publisher : Springer
ISBN 13 : 9783030498146
Total Pages : 0 pages
Book Rating : 4.4/5 (981 download)

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Book Synopsis Digital Health in Focus of Predictive, Preventive and Personalised Medicine by : Lotfi Chaari

Download or read book Digital Health in Focus of Predictive, Preventive and Personalised Medicine written by Lotfi Chaari and published by Springer. This book was released on 2020-10-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The edition will cover proceedings of the second International conference on digital health Technologies (ICDHT 2019). The conference will address the topic of P4 medicine from the information technology point of view, and will be focused on the following topics: - Artificial Intelligence for health • Knowledge extraction • Decision-aid systems • Data analysis and risk prediction • Machine learning, deep learning - Health data processing • Data preprocessing, cleaning, management and mining • Computer-aided detection • Big data analysis, prediction and prevention • Cognitive algorithms for healthcare handling dynamic context management • Augmented reality, Motion detection and activity recognition - Devices, infrastructure and communication • Wearable & connected devices • Communication infrastructures, architectures and standards Blockchain for e-Health • Computing/storage infrastructures for e-Health • IoT devices & architectures for Smart Healthcare - Health information systems • Telemedicine, Teleservices • Computing/storage infrastructures for e-Health • Clinical Data Visualisation Standards - Security and privacy for e-health • Health data Analytics for Security and Privacy • E-health Software and Hardware Security • Embedded Security for e-health - Applications in P4 medicine

Preventive and Predictive Genetics: Towards Personalised Medicine

Author : Godfrey Grech
Publisher : Springer
ISBN 13 : 3319153447
Total Pages : 388 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Preventive and Predictive Genetics: Towards Personalised Medicine by : Godfrey Grech

Download or read book Preventive and Predictive Genetics: Towards Personalised Medicine written by Godfrey Grech and published by Springer. This book was released on 2015-06-24 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmacogenomics supports personalized medicine by translating genome-based knowledge into clinical practice, offering enhanced benefit for patients and health-care systems at large. Current routine practice for diagnosing and treating patients is conducted by correlating parameters such as age, gender and weight with risks and expected treatment outcomes. In the new era of personalized medicine the healthcare provider is equipped with improved ability to prevent, diagnose, treat and predict outcomes on the basis of complex information sources, including genetic and genomic data. Targeted therapy and reliable prediction of expected outcomes offer patients access to better healthcare management, by way of identifying the therapies effective for the relevant patient group, avoiding prescription of unnecessary treatment and reducing the likelihood of developing adverse drug reactions.

Neurodegenerative Diseases: Integrative PPPM Approach as the Medicine of the Future

Author : Silvia Mandel
Publisher : Springer Science & Business Media
ISBN 13 : 9400758669
Total Pages : 402 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Neurodegenerative Diseases: Integrative PPPM Approach as the Medicine of the Future by : Silvia Mandel

Download or read book Neurodegenerative Diseases: Integrative PPPM Approach as the Medicine of the Future written by Silvia Mandel and published by Springer Science & Business Media. This book was released on 2013-03-12 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book will compile a collection of chapters dedicated to varied aspects of PPPM in neuropsychiatric and neurodegenerative diseases. Among the topics to be covered are: Recent advances in ALS research News about Clinical aspects and advanced therapy approaches in personalized treatment of ALS Schizophrenia: New treatments and clinical aspects Predictive, Preventive and Personalised Medicine in aging macular degeneration Advances in Multiple Sclerosis Pharmacogenetics, Tailoring Treatment Efficacy, Safety and Regimen Selection Multiple sclerosis related biomarkers: perspectives for clinical application Preventive clinical trials in brain aging: new trends & the need of guidelines MCI_ clinical guidelines in early diagnosis of dementia Alzheimer's disease: diagnostics, prognostics and the road to prevention Biomarkers for early diagnosis of Parkinson's and Alzheimer's diseases Synucleinopathies, tauopathies, TDP-43 proteinopathies and amyloidosis PSP, MSA and other parkinsonisms

Personalized Medicine in Oncology

Author : Ari VanderWalde
Publisher :
ISBN 13 : 9783036528205
Total Pages : 174 pages
Book Rating : 4.5/5 (282 download)

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Book Synopsis Personalized Medicine in Oncology by : Ari VanderWalde

Download or read book Personalized Medicine in Oncology written by Ari VanderWalde and published by . This book was released on 2022 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nowhere is the explosion in comprehensive genomic testing more evident than in oncology. Multiple consensus guidelines now recommend molecular testing as the standard of care for most metastatic tumors. To aid in the advancement of this rapidly changing field, we intend this Special Issue of JPM to focus on technical developments in the genomic profiling of cancer, detail promising somatic alterations that either are, or have a high likelihood of being, relevant in the near future, and to address issues related to the pricing and value of these tests.The last few years have seen the cost of molecular testing decrease by orders of magnitude. In 2018, we saw the first “site-agnostic” drug approvals in cancer (for microsatellite unstable cancer (PD-1 inhibitors) and NTRK-fusions (TRK inhibitors)). Research on targetable mutations, determination of genetic “signatures” that can use multiple individual genes/pathways, development of targeted therapy, and insight into the value of new technology remains at the cutting edge of research in this field. We are soliciting papers that present new technologies to assess predictive biomarkers in cancer, original research (pre-clinical or clinical) that demonstrates promise for particular targeted therapies in cancer, and articles that explore the clinical and financial impacts of this paradigmatic shift in cancer diagnostics and treatment.

Toward Precision Medicine

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309222222
Total Pages : 142 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis Toward Precision Medicine by : National Research Council

Download or read book Toward Precision Medicine written by National Research Council and published by National Academies Press. This book was released on 2012-01-16 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt: Motivated by the explosion of molecular data on humans-particularly data associated with individual patients-and the sense that there are large, as-yet-untapped opportunities to use this data to improve health outcomes, Toward Precision Medicine explores the feasibility and need for "a new taxonomy of human disease based on molecular biology" and develops a potential framework for creating one. The book says that a new data network that integrates emerging research on the molecular makeup of diseases with clinical data on individual patients could drive the development of a more accurate classification of diseases and ultimately enhance diagnosis and treatment. The "new taxonomy" that emerges would define diseases by their underlying molecular causes and other factors in addition to their traditional physical signs and symptoms. The book adds that the new data network could also improve biomedical research by enabling scientists to access patients' information during treatment while still protecting their rights. This would allow the marriage of molecular research and clinical data at the point of care, as opposed to research information continuing to reside primarily in academia. Toward Precision Medicine notes that moving toward individualized medicine requires that researchers and health care providers have access to very large sets of health- and disease-related data linked to individual patients. These data are also critical for developing the information commons, the knowledge network of disease, and ultimately the new taxonomy.

Clinical Molecular Diagnostics

Author : Shiyang Pan
Publisher : Springer Nature
ISBN 13 : 9811610371
Total Pages : 889 pages
Book Rating : 4.8/5 (116 download)

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Book Synopsis Clinical Molecular Diagnostics by : Shiyang Pan

Download or read book Clinical Molecular Diagnostics written by Shiyang Pan and published by Springer Nature. This book was released on 2021-07-08 with total page 889 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the discovery of molecular biomarkers, the development of laboratory testing techniques and their clinical applications, focusing on basic research to clinical practice. It introduces new and crucial knowledge and ethics of clinical molecular diagnosis. This book emphasizes the applications of clinical molecular diagnostic test on health management, especially from different diseased organs. It lets readers to understand and realize precision healthcare.

Genomic and Personalized Medicine

Author : Geoffrey S. Ginsburg
Publisher : Academic Press
ISBN 13 : 0123822270
Total Pages : 1343 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis Genomic and Personalized Medicine by : Geoffrey S. Ginsburg

Download or read book Genomic and Personalized Medicine written by Geoffrey S. Ginsburg and published by Academic Press. This book was released on 2012-11-29 with total page 1343 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genomic and Personalized Medicine, Second Edition - winner of a 2013 Highly Commended BMA Medical Book Award for Medicine - is a major discussion of the structure, history, and applications of the field, as it emerges from the campus and lab into clinical action. As with the first edition, leading experts review the development of the new science, the current opportunities for genome-based analysis in healthcare, and the potential of genomic medicine in future healthcare. The inclusion of the latest information on diagnostic testing, population screening, disease susceptability, and pharmacogenomics makes this work an ideal companion for the many stakeholders of genomic and personalized medicine. With advancing knowledge of the genome across and outside protein-coding regions of DNA, new comprehension of genomic variation and frequencies across populations, the elucidation of advanced strategic approaches to genomic study, and above all in the elaboration of next-generation sequencing, genomic medicine has begun to achieve the much-vaunted transformative health outcomes of the Human Genome Project, almost a decade after its official completion in April 2003. Highly Commended 2013 BMA Medical Book Award for Medicine More than 100 chapters, from leading researchers, review the many impacts of genomic discoveries in clinical action, including 63 chapters new to this edition Discusses state-of-the-art genome technologies, including population screening, novel diagnostics, and gene-based therapeutics Wide and inclusive discussion encompasses the formidable ethical, legal, regulatory and social challenges related to the evolving practice of genomic medicine Clearly and beautifully illustrated with 280 color figures, and many thousands of references for further reading and deeper analysis

Personalized Medicine in Anesthesia, Pain and Perioperative Medicine

Author : Ali Dabbagh
Publisher : Springer Nature
ISBN 13 : 3030535258
Total Pages : 401 pages
Book Rating : 4.0/5 (35 download)

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Book Synopsis Personalized Medicine in Anesthesia, Pain and Perioperative Medicine by : Ali Dabbagh

Download or read book Personalized Medicine in Anesthesia, Pain and Perioperative Medicine written by Ali Dabbagh and published by Springer Nature. This book was released on 2020-09-21 with total page 401 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses the current and future impact of cellular and molecular medicine (CMM) on anesthesiology and perioperative medicine. It covers the topic from a translational perspective and describes the relevance of CMM to daily clinical practice. Taking a bench-to-bedside approach, chapters examine topics including perioperative acute and chronic management, perioperative organ protection, and novel pharmaceuticals. Personalized Medicine in Anesthesia, Pain and Perioperative Medicine is aimed at anesthesiologists and pain physicians, and will also be of interest to pharmacists and those working in cellular and molecular medicine.

Nanoarchitectonics for Brain Drug Delivery

Author : Anurag Kumar Singh
Publisher : CRC Press
ISBN 13 : 1003851843
Total Pages : 381 pages
Book Rating : 4.0/5 (38 download)

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Book Synopsis Nanoarchitectonics for Brain Drug Delivery by : Anurag Kumar Singh

Download or read book Nanoarchitectonics for Brain Drug Delivery written by Anurag Kumar Singh and published by CRC Press. This book was released on 2024-02-22 with total page 381 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses basics of brain diseases and the role of nanobiotechnology in existing treatment options for neurodegenerative disorders. It begins with an overview of brain diseases and the need for novel drug-delivery approaches. It highlights the current route for the intranasal advanced drug-delivery systems for brain diseases. It also discusses innovative categories of drug-delivery systems, including mesoporous silica nanoparticles, polymeric nanocarriers, and lipid-based nanocarriers through multi-responsive DDSs and their implications in brain disorders. Features: Includes an overview of brain diseases and highlights the need for novel drug-delivery approaches Focuses on theoretical aspects of advanced drug-delivery systems for brain diseases including challenges and progress in nose-to-brain delivery Provides an overview of technological approaches and their implications for neurodegenerative disorders, central nervous system (CNS), and brain drug delivery in brain cancer Discusses key advances in the development of polymer nanoparticles for drug delivery to the CNS Reviews the role of herbal medicines and naturally derived polymeric nanoparticle for the treatment of neurodegenerative disorders This book is aimed at graduate students and researchers in biomedical engineering, biotechnology, drug delivery, and neurology.

Oxford Textbook of Global Public Health

Author : Roger Detels
Publisher : Oxford University Press
ISBN 13 : 019881013X
Total Pages : 1717 pages
Book Rating : 4.1/5 (988 download)

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Book Synopsis Oxford Textbook of Global Public Health by : Roger Detels

Download or read book Oxford Textbook of Global Public Health written by Roger Detels and published by Oxford University Press. This book was released on 2017 with total page 1717 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sixth edition of the hugely successful, internationally recognised textbook on global public health and epidemiology, with 3 volumes comprehensively covering the scope, methods, and practice of the discipline

Comprehensive Biomarker Discovery and Validation for Clinical Application

Author : Péter Horvatovich
Publisher : Royal Society of Chemistry
ISBN 13 : 1849734364
Total Pages : 385 pages
Book Rating : 4.8/5 (497 download)

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Book Synopsis Comprehensive Biomarker Discovery and Validation for Clinical Application by : Péter Horvatovich

Download or read book Comprehensive Biomarker Discovery and Validation for Clinical Application written by Péter Horvatovich and published by Royal Society of Chemistry. This book was released on 2013-06-17 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on proteomics biomarker discovery and validation procedures from the clinical perspective. It provides an overview of current technology and the challenges encountered throughout the process. This covers all key stages, from biomarker discovery and validation, through to registration with the European and US regulatory authorities (FDA and EMEA). All the important elements (such as patient selection, sample handling, data processing, and statistical analysis) are described in detail and the reader is introduced to each topic with well-described examples or guidelines for best practice. Case studies are also included to demonstrate clinical applications. Individual chapters explain the best performing techniques for profiling complex body fluids and biomarker discovery. This includes the application of mass spectrometry imaging combined with chromatography in profiling platforms and the use of laser micro dissection and MALDI imaging to study tissues in their natural environment. Future developments needed to improve the success rate of translating biomarker discovery into useful clinical tests are also discussed. Common pitfalls and success stories are described as are the limitations of the various technologies involved. Broad and interdisciplinary in approach, this book provides an excellent source of information for industrial and academic researchers, and those managing biobanks.