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Author : Tobias Kieser
Publisher :
ISBN 13 : 9780708406236
Total Pages : 613 pages
Book Rating : 4.4/5 (62 download)
Download or read book Practical Streptomyces Genetics written by Tobias Kieser and published by . This book was released on 2000-01-01 with total page 613 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Simon Baumberg
Publisher : Springer Science & Business Media
ISBN 13 : 1468459228
Total Pages : 318 pages
Book Rating : 4.4/5 (684 download)
Download or read book Genetics and Product Formation in Streptomyces written by Simon Baumberg and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Streptomycetes are industrially widely used microorganisms due to their ability to produce numerous different chemical compounds. These show very varied effects upon other living systems, and result from profound and subtle biochemical and morphological differentiation during the streptomycete life cycle. It is therefore not surprising that research on the genetics of antibiotic biosynthesis and differentiation in this group is currently progressing rapidly in many countries. Intimately connected with the production of antibiotics is resistance to them; analysis of this is giving further information about the origin and evolution of this class of genes and their hypothesized spread among other microorganisms. Another interesting feature of the Streptomyces group is their mycelial growth. Also, their ecologically important utilization of high molecular weight compounds requires enzymes to be transported outside the cell to hydrolyze non-diffusible substrates. Finally, we have as yet limited understanding of the various mechanisms of genome rearrangement observed in some of these species; deletions and/or amplifications of enormous amounts of DNA can occur without seriously affecting the viability of the organism under laboratory conditions. The present volume, which includes contributions addressing the above subjects and others, originates from a meeting on "Genetics and Product Formation in Streptomyces" sponsored by the Federation of European Microbiological Societies in Erfurt on May 1-6 1990. Compared to previous ones of this kind held in 1979, 1983 and 1987 in Weimar, one can point to impressive progress in the study and applications of Streptomyces genetics.
Author : D. A. Hopwood
Publisher : Oxford University Press
ISBN 13 : 019515066X
Total Pages : 261 pages
Book Rating : 4.1/5 (951 download)
Download or read book Streptomyces in Nature and Medicine written by D. A. Hopwood and published by Oxford University Press. This book was released on 2007-02-03 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is an insiders account of 50 years of genetic studies of the soil-inhabiting microbes that produce most of the antibiotics used to treat infections, as well as anti-cancer, anti-parasitic and immunosuppressant drugs. The book begins by describing how these microbes the actinomycetes were discovered in the latter part of the nineteenth century, but remained a Cinderella group until, in the 1940s, they shot to prominence with the discovery of streptomycin, the first effective treatment for tuberculosis and only the second antibiotic, after penicillin, to become a medical marvel. There followed a massive effort over several decades to find further treatments for infectious diseases and cancer, tempered by the rise of antibiotic resistance consequent on antibiotic misuse and over-use. The book goes on to describe the discovery of gene exchange in the actinomycetes in the context of the rise of microbial genetics in the mid-20th century, leading to determination of the complete DNA sequence of a model member of the group at the turn of the millennium. There follow chapters in which the intricate molecular machinery that adapts the organisms metabolism and development to life in the soil, including antibiotic production, is illuminated by the DNA blueprint. Then come an up-to-the minute account of the use of genetic engineering to make novel, hybrid, antibiotics, and a topical description of techniques to learn the roles of the thousands of genes in a genome sequence, throwing a powerful light on the biology of the organisms and their harnessing for increasing antibiotic productivity. In the final chapter we return to the mycobacteria that cause tuberculosis and leprosy, the first actinomycetes to be discovered, and how methodology, in part derived from the study of the streptomycetes, is being applied to understand and control these still deadly pathogens.
Author : D. A. Hopwood
Publisher :
ISBN 13 :
Total Pages : 378 pages
Book Rating : 4.3/5 (91 download)
Download or read book Genetic Manipulation of Streptomyces written by D. A. Hopwood and published by . This book was released on 1985 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : David A. Hopwood
Publisher :
ISBN 13 : 9780879699932
Total Pages : 356 pages
Book Rating : 4.6/5 (999 download)
Download or read book Genetic Manipulation of Streptomyces written by David A. Hopwood and published by . This book was released on 1985-01-01 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Stanley Maloy
Publisher : Academic Press
ISBN 13 : 0080961568
Total Pages : 4360 pages
Book Rating : 4.0/5 (89 download)
Download or read book Brenner's Encyclopedia of Genetics written by Stanley Maloy and published by Academic Press. This book was released on 2013-03-03 with total page 4360 pages. Available in PDF, EPUB and Kindle. Book excerpt: The explosion of the field of genetics over the last decade, with the new technologies that have stimulated research, suggests that a new sort of reference work is needed to keep pace with such a fast-moving and interdisciplinary field. Brenner's Encyclopedia of Genetics, Second Edition, Seven Volume Set, builds on the foundation of the first edition by addressing many of the key subfields of genetics that were just in their infancy when the first edition was published. The currency and accessibility of this foundational content will be unrivalled, making this work useful for scientists and non-scientists alike. Featuring relatively short entries on genetics topics written by experts in that topic, Brenner's Encyclopedia of Genetics, Second Edition, Seven Volume Set provides an effective way to quickly learn about any aspect of genetics, from Abortive Transduction to Zygotes. Adding to its utility, the work provides short entries that briefly define key terms, and a guide to additional reading and relevant websites for further study. Many of the entries include figures to explain difficult concepts. Key terms in related areas such as biochemistry, cell, and molecular biology are also included, and there are entries that describe historical figures in genetics, providing insights into their careers and discoveries. This 7-volume set represents a 25% expansion from the first edition, with over 1600 articles encompassing this burgeoning field Thoroughly up-to-date, with many new topics and subfields covered that were in their infancy or not inexistence at the time of the first edition. Timely coverage of emergent areas such as epigenetics, personalized genomic medicine, pharmacogenetics, and genetic enhancement technologies Interdisciplinary and global in its outlook, as befits the field of genetics Brief articles, written by experts in the field, which not only discuss, define, and explain key elements of the field, but also provide definition of key terms, suggestions for further reading, and biographical sketches of the key people in the history of genetics
Author :
Publisher : Academic Press
ISBN 13 : 0080923356
Total Pages : 703 pages
Book Rating : 4.0/5 (89 download)
Download or read book Complex Enzymes in Microbial Natural Product Biosynthesis, Part A: Overview Articles and Peptides written by and published by Academic Press. This book was released on 2009-04-10 with total page 703 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbial natural products have been an important traditional source of valuable antibiotics and other drugs but interest in them waned in the 1990s when big pharma decided that their discovery was no longer cost-effective and concentrated instead on synthetic chemistry as a source of novel compounds, often with disappointing results. Moreover understanding the biosynthesis of complex natural products was frustratingly difficult. With the development of molecular genetic methods to isolate and manipulate the complex microbial enzymes that make natural products, unexpected chemistry has been revealed and interest in the compounds has again flowered. This two-volume treatment of the subject will showcase the most important chemical classes of complex natural products: the peptides, made by the assembly of short chains of amino acid subunits, and the polyketides, assembled from the joining of small carboxylic acids such as acetate and malonate. In both classes, variation in sub-unit structure, number and chemical modification leads to an almost infinite variety of final structures, accounting for the huge importance of the compounds in nature and medicine. Gathers tried and tested methods and techniques from top players in the field In depth coverage of ribosomally-synthesised and Non-ribosomally-synthesised peptides Provides an extremely useful reference for the experienced research scientist
Author :
Publisher : Academic Press
ISBN 13 : 0080923364
Total Pages : 644 pages
Book Rating : 4.0/5 (89 download)
Download or read book Complex Enzymes in Microbial Natural Product Biosynthesis, Part B: Polyketides, Aminocoumarins and Carbohydrates written by and published by Academic Press. This book was released on 2009-04-11 with total page 644 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbial natural products have been an important traditional source of valuable antibiotics and other drugs but interest in them waned in the 1990s when big pharma decided that their discovery was no longer cost-effective and concentrated instead on synthetic chemistry as a source of novel compounds, often with disappointing results. Moreover understanding the biosynthesis of complex natural products was frustratingly difficult. With the development of molecular genetic methods to isolate and manipulate the complex microbial enzymes that make natural products, unexpected chemistry has been revealed and interest in the compounds has again flowered. This two-volume treatment of the subject will showcase the most important chemical classes of complex natural products: the peptides, made by the assembly of short chains of amino acid subunits, and the polyketides, assembled from the joining of small carboxylic acids such as acetate and malonate. In both classes, variation in sub-unit structure, number and chemical modification leads to an almost infinite variety of final structures, accounting for the huge importance of the compounds in nature and medicine. Gathers tried and tested methods and techniques from top players in the field Provides an extremely useful reference for the experienced research scientist Covers biosynthesis of Polyketides, Tarpenoids, Aminocoumarins and Crabohydrates
Author : Dongyou Liu
Publisher : CRC Press
ISBN 13 : 1439812381
Total Pages : 1282 pages
Book Rating : 4.4/5 (398 download)
Download or read book Molecular Detection of Human Bacterial Pathogens written by Dongyou Liu and published by CRC Press. This book was released on 2011-04-18 with total page 1282 pages. Available in PDF, EPUB and Kindle. Book excerpt: As more original molecular protocols and subsequent modifications are described in the literature, it has become difficult for those not directly involved in the development of these protocols to know which are most appropriate to adopt for accurate identification of bacterial pathogens. Molecular Detection of Human Bacterial Pathogens addresses this issue, with international scientists in respective bacterial pathogen research and diagnosis providing expert summaries on current diagnostic approaches for major human bacterial pathogens. Each chapter consists of a brief review on the classification, epidemiology, clinical features, and diagnosis of an important pathogenic bacterial genus, an outline of clinical sample collection and preparation procedures, a selection of representative stepwise molecular protocols, and a discussion on further research requirements relating to improved diagnosis. This book represents a reliable and convenient reference on molecular detection and identification of major human bacterial pathogens; an indispensable tool for upcoming and experienced medical, veterinary, and industrial laboratory scientists engaged in bacterial characterization; and an essential textbook for undergraduate and graduate students in microbiology.
Author : Kan Wang
Publisher : Springer Science & Business Media
ISBN 13 : 1597451312
Total Pages : 473 pages
Book Rating : 4.5/5 (974 download)
Download or read book Agrobacterium Protocols written by Kan Wang and published by Springer Science & Business Media. This book was released on 2008-02-05 with total page 473 pages. Available in PDF, EPUB and Kindle. Book excerpt: Agrobacterium tumefaciens is a soil bacterium that for more than a century has been known as a pathogen causing the plant crown gall disease. Unlike many other pathogens, Agrobacterium has the ability to deliver DNA to plant cells and permanently alter the plant genome. The discovery of this unique feature 30 years ago has provided plant scientists with a powerful tool to genetically transform plants for both basic research purposes and for agric- tural development. Compared to physical transformation methods such as particle bomba- ment or electroporation, Agrobacterium-mediated DNA delivery has a number of advantages. One of the features is its propensity to generate single or a low copy number of integrated transgenes with defined ends. Integration of a single transgene copy into the plant genome is less likely to trigger “gene silencing” often associated with multiple gene insertions. When the first edition of Agrobacterium Protocols was published in 1995, only a handful of plants could be routinely transformed using Agrobacterium. Ag- bacterium-mediated transformation is now commonly used to introduce DNA into many plant species, including monocotyledon crop species that were previously considered non-hosts for Agrobacterium. Most remarkable are recent devel- ments indicating that Agrobacterium can also be used to deliver DNA to non-plant species including bacteria, fungi, and even mammalian cells.
Author : Yvonne Mast
Publisher : Frontiers Media SA
ISBN 13 : 2889639959
Total Pages : 184 pages
Book Rating : 4.8/5 (896 download)
Download or read book Regulation of Antibiotic Production in Actinomycetes written by Yvonne Mast and published by Frontiers Media SA. This book was released on 2020-09-08 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Author : Muhammad Zaffar Hashmi
Publisher : Elsevier
ISBN 13 : 0128188839
Total Pages : 434 pages
Book Rating : 4.1/5 (281 download)
Download or read book Antibiotics and Antimicrobial Resistance Genes in the Environment written by Muhammad Zaffar Hashmi and published by Elsevier. This book was released on 2019-11-22 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antibiotics and Antimicrobial Resistance Genes (AMR) in the Environment summarizes and updates information on antibiotic producing organisms and their resistance and entry routes in soil, air, water and sediment. As antibiotic use continues to rise in healthcare, their fate, bioavailability and biomonitoring, and impacts on environment and public health are becoming increasingly important. The book addresses the impact of antibiotics and AMR to environment and public health and risk assessment. Moreover, it focused on the metagenomics and molecular techniques for the detection of antibiotics and antimicrobial genes. Lastly, it introduces management strategies, such as treatment technologies for managing antibiotics and AMR/ARGs-impacted environment, and bioremediation approaches. Summarizes and updates information on antibiotics and AMR/ARGs production and its fate and transport in the environment Includes phytoremediation and bioremediation technologies for environmental management Provides analysis of risk assessment of antibiotic resistance genes to help understand the environmental and socioeconomic impacts of antibiotics and AMR/ARGs
Author :
Publisher : Elsevier
ISBN 13 : 0080546366
Total Pages : 425 pages
Book Rating : 4.0/5 (85 download)
Download or read book Advances in Applied Microbiology written by and published by Elsevier. This book was released on 2005-01-06 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Applied Microbiology offers intensive reviews of the latest techniques and discoveries in this rapidly moving field. The editors are recognized experts and the format is comprehensive and instructive. This volume contains 12 comprehensive reviews, including: Uses of Trichoderma spp. to alleviate or remediate soil and water pollution; Lincosamides, chemical structure, biosynthesis, mechanism of action, resistance and applications; Polysaccharide breakdown by anaerobic microogranisms inhabiting the mammalian gut; and Novel aspects of signaling in Streptomyces development. * This series has been in constant publication since 1959 * An ISI impact factor of 1.0 in 2002 * This volume contains 12 comprehensive reviews of current research in applied microbiology
Author : Sankar Adhya
Publisher : Elsevier
ISBN 13 : 0080522599
Total Pages : 833 pages
Book Rating : 4.0/5 (85 download)
Download or read book RNA Polymerase and Associated Factors, Part C written by Sankar Adhya and published by Elsevier. This book was released on 2003-12-18 with total page 833 pages. Available in PDF, EPUB and Kindle. Book excerpt: RNA polymerase is molecule important to gene transcription. Along with associated factors, RNA polymerase is part of the process in which RNA is transcribed to produce a protein. * Construction and purification of RNA polymerases* DNA microarrays and bacterial gene expression* Functional analysis of transcription factors
Author : Krishnamoorthy Venkataraman
Publisher : Academic Press
ISBN 13 : 012801962X
Total Pages : 542 pages
Book Rating : 4.1/5 (28 download)
Download or read book Marine Faunal Diversity in India written by Krishnamoorthy Venkataraman and published by Academic Press. This book was released on 2014-11-21 with total page 542 pages. Available in PDF, EPUB and Kindle. Book excerpt: More than 70% of the earth’s surface is covered by water, making it an ideal and abundant resource for studying species diversity, faunal communities, and ecosystems. India’s massive coastline (5,044 miles) means it plays a major role in housing these faunal communities. Of the 32 animal phyla, 15 are represented in India’s marine ecosystem, covering more than 15,000 species. Marine and coastal ecosystems of India provide supporting services in the form of wide range of habitats. Major ecosystems such as estuaries, mangroves, coral reefs, lagoons, seaweeds and sea grasses serve as nurseries for both inshore and offshore fishes and others, many of which are supposed to be commercially exploited. Marine Faunal Diversity in India describes different marine faunal group ranges from sponges, corals, mollusks, crabs, fishes, reptiles, birds, marine mammals, mangrove fauna and tsunami impact on marine faunal diversity. The chapters, written by reputed experts in their respective fields, illustrate diversity and distribution of marine faunal communities. Key aspects of the ecology and conservation of this important ecosystem are also discussed. Marine Faunal Diversity in India provides marine biologists and related researchers with access to the latest research and field studies from this major region. Provides the latest field research on marine faunal diversity throughout the vast and species-rich Indian region Brings together expertise from top marine biology researchers in the country Covers a diverse array of aquatic environments, including coastal and island areas Discusses conservation ecology of marine faunal groups
Author : H.B Singh
Publisher : Elsevier
ISBN 13 : 0444635106
Total Pages : 256 pages
Book Rating : 4.4/5 (446 download)
Download or read book New and Future Developments in Microbial Biotechnology and Bioengineering written by H.B Singh and published by Elsevier. This book was released on 2018-10-19 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: New and Future Developments in Microbial Biotechnology and Bioengineering: Microbial Genes Biochemistry and Applications consolidates the most widely used genetic methods available, bringing together the fields of biochemistry, biotechnology, and microbiology. The chapters outlined give clear and concise direction on both standard and applied microbial genetic improvements, presenting undergraduates, postgraduates, and researchers with the latest developments in microbial gene technology. In addition, the book describes the background and usefulness of each experiment in question. All chapters covered in the book are derived from current peer-reviewed literature as accepted by the international scientific community. Compiles the latest developments made in the area of microbial gene systems Includes exhaustive information on almost all areas of microbial gene technology Relates microbial engineering and its direct application to the production of many useful compounds Written by an international team of authors and compiled by award winning editors
Author : Maria Julia Amoroso
Publisher : CRC Press
ISBN 13 : 1466578734
Total Pages : 299 pages
Book Rating : 4.4/5 (665 download)
Download or read book Actinobacteria written by Maria Julia Amoroso and published by CRC Press. This book was released on 2013-03-12 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes isolated actinobacteria from different environments, and how these can be used to bioremediate heavy metals and pesticides in contaminated sites. It also describes how free-living actinobacteria acquire the capability to produce nodules in plants and how this factor could be important for accelerating the degradation of pesticides in soils or slurries. Some chapters show how actinobacteria can be used to produce industrial enzymes and metabolites under different physicochemical conditions for use in the food industry. This book will interest professionals involved with waste management, environmental protection, and pollution abatement.
