Heme and Hemoproteins

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3642667635
Total Pages : 461 pages
Book Rating : 4.6/5 (426 download)

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Book Synopsis Heme and Hemoproteins by : K.W. Bock

Download or read book Heme and Hemoproteins written by K.W. Bock and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 461 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of the biological effects of foreign chemicals (whether therapeutic drugs or chemicals present at work or in the environment) interests the biologist from a number of different and complementary viewpoints. Apart from the more obvious pharmacological and toxicological interest, the experimentalist often uses foreign chemicals to produce in experimental animals disease states similar to naturally occurring diseases, so that their pathogenetic mechanisms and therapy can be studied under controlled conditions. In addition - as Claude Bernard pointed out over a century ago - foreign chemicals can be employed as instruments to analyze the most delicate vital processes; much can be learned about the physiological processes themselves by a careful study of the mechanisms by which these are altered by chemicals. The field of heme and hemoproteins offers an example of the interplay of these different approaches. Their metabolism can be altered by therapeutic drugs and other foreign chemicals and this results in a variety of biological responses that transcend the boundaries of pharmacology into the confines of clinical medi cine, genetics, toxicology, biochemistry and physiology. In this book a multidisciplinary approach to the study of heme metabolism is presented including the effect of chemicals on heme metabolism in patients, the results of experimental work in the whole animal, as well as in vitro studies.

Handbook Of Porphyrin Science: With Applications To Chemistry, Physics, Materials Science, Engineering, Biology And Medicine (Volumes 21-25)

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Author :
Publisher : World Scientific
ISBN 13 : 981439761X
Total Pages : 2068 pages
Book Rating : 4.8/5 (143 download)

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Book Synopsis Handbook Of Porphyrin Science: With Applications To Chemistry, Physics, Materials Science, Engineering, Biology And Medicine (Volumes 21-25) by : Roger Guilard

Download or read book Handbook Of Porphyrin Science: With Applications To Chemistry, Physics, Materials Science, Engineering, Biology And Medicine (Volumes 21-25) written by Roger Guilard and published by World Scientific. This book was released on 2012-06-25 with total page 2068 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the fifth set of Handbook of Porphyrin Science.Porphyrins, phthalocyanines and their numerous analogues and derivatives are materials of tremendous importance in chemistry, materials science, physics, biology and medicine. They are the red color in blood (heme) and the green in leaves (chlorophyll); they are also excellent ligands that can coordinate with almost every metal in the Periodic Table. Grounded in natural systems, porphyrins are incredibly versatile and can be modified in many ways; each new modification yields derivatives, demonstrating new chemistry, physics and biology, with a vast array of medicinal and technical applications.As porphyrins are currently employed as platforms for study of theoretical principles and applications in a wide variety of fields, the Handbook of Porphyrin Science represents a timely ongoing series dealing in detail with the synthesis, chemistry, physicochemical and medical properties and applications of polypyrrole macrocycles. Professors Karl Kadish, Kevin Smith and Roger Guilard are internationally recognized experts in the research field of porphyrins, each having his own separate area of expertise in the field. Between them, they have published over 1500 peer-reviewed papers and edited more than three dozen books on diverse topics of porphyrins and phthalocyanines. In assembling the new volumes of this unique handbook, they have selected and attracted the very best scientists in each sub-discipline as contributing authors.This handbook will prove to be a modern authoritative treatise on the subject as it is a collection of up-to-date works by world-renowned experts in the field. Complete with hundreds of figures, tables and structural formulas, and thousands of literature citations, all researchers and graduate students in this field will find the Handbook of Porphyrin Science an essential, major reference source for many years to come.

Diseases of Porphyrin Metabolism

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Publisher :
ISBN 13 :
Total Pages : 252 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Diseases of Porphyrin Metabolism by : Abraham Goldberg

Download or read book Diseases of Porphyrin Metabolism written by Abraham Goldberg and published by . This book was released on 1962 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Toxicology and Experimental Models

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Publisher : Elsevier
ISBN 13 : 1483148483
Total Pages : 366 pages
Book Rating : 4.4/5 (831 download)

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Book Synopsis Toxicology and Experimental Models by : H. Yoshida

Download or read book Toxicology and Experimental Models written by H. Yoshida and published by Elsevier. This book was released on 2013-10-22 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Pharmacology and Therapeutics II, Volume 5: Toxicology and Experimental Models is the fifth of a six-volume compilation of the scientific papers of invited speakers of the Eighth International Congress of Pharmacology. Organized into six parts, this book begins by elucidating the rational interpretation of species and strain differences in toxicity for the prediction of risk to man. Subsequent parts discuss the chemical interactions resulting in liver and kidney injury; the role of heme synthesis and degradation in predicting drug toxicity; and delayed toxic effects of pre- and perinatal drug exposure. Other chapters describe models of experimental peptic ulcers and therapeutic agents and models and quality control of laboratory animals.

Tetrapyrroles

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Publisher : Springer Science & Business Media
ISBN 13 : 0387785183
Total Pages : 406 pages
Book Rating : 4.3/5 (877 download)

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Book Synopsis Tetrapyrroles by : Martin Warren

Download or read book Tetrapyrroles written by Martin Warren and published by Springer Science & Business Media. This book was released on 2009-12-21 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: Excluding the biological polymers proteins, lipids and nucleic acids, modified tetrapyrroles are the biological molecules that have had the greatest impact on the evolution of life over the past 4 billion years. They are involved in a wide variety of fundamental processes that underpin central primary metabolism in all kingdoms of life, from photosynthesis to methanogenesis. Moreover, they bring colour into the world and it is for this reason that these compounds have been appropriately dubbed the ‘pigments of life’. To understand how and why these molecules have been so universally integrated into the life processes one has to appreciate the chemical properties of the tetrapyrrole scaffold and, where appropriate, the chemical characteristics of the centrally chelated metal ion. This book addresses why these molecules are employed in Nature, how they are made and what happens to them after they have finished their usefulness.

Symposium of the Society of General Physiologists

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Publisher :
ISBN 13 :
Total Pages : 378 pages
Book Rating : 4.E/5 ( download)

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Book Synopsis Symposium of the Society of General Physiologists by :

Download or read book Symposium of the Society of General Physiologists written by and published by . This book was released on 1963 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Haematin Enzymes

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Publisher : Elsevier
ISBN 13 : 1483221490
Total Pages : 388 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Haematin Enzymes by : J. E. Falk

Download or read book Haematin Enzymes written by J. E. Falk and published by Elsevier. This book was released on 2014-05-12 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: International Union of Biochemistry, Volume 19: Haematin Enzymes, Part 1 provides information pertinent to the fundamental aspects of hematin enzymes. This book covers a variety of topics, including porphyrin complexes, chemical reactions of iron complexes, hemoprotein molecules, metalloporphyrins, and oxyhemoglobins. Organized into 22 chapters, this volume begins with an overview of the relevance of magnetic susceptabilitty and magnetic resonance data. This text then examines studies on electron-transfer processes involving metal ions and shows how the electronic structures of the hem enzymes may be relevant to the types of electron-transfer that can take place. Other chapters consider the implications of the coordination of organic molecules to metal ions. This book presents as well a comparison between known properties and reactions of some simple iron complexes with chelating and conjugated ligands. The final chapter deals with the chemical structures of the prosthetic groups of the cytochromes of type a. This book is a valuable resource for scientists, theorists, and research workers.

Methods of Biochemical Analysis

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Publisher : John Wiley & Sons
ISBN 13 : 0470110694
Total Pages : 410 pages
Book Rating : 4.4/5 (71 download)

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Book Synopsis Methods of Biochemical Analysis by : David Glick

Download or read book Methods of Biochemical Analysis written by David Glick and published by John Wiley & Sons. This book was released on 2009-09-24 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biochemical analysis is a rapidly expanding field and is a key component of modern drug discovery and research. Methods of Biochemical Analysis provides a periodic and authoritative review of the latest achievements in biochemical analysis. Founded in 1954 by Professor David Glick, Methods of Biochemical Analysis provides a timely review of the latest developments in the field.

National Union Catalog

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Publisher :
ISBN 13 :
Total Pages : 648 pages
Book Rating : 4.E/5 ( download)

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Book Synopsis National Union Catalog by :

Download or read book National Union Catalog written by and published by . This book was released on 1953 with total page 648 pages. Available in PDF, EPUB and Kindle. Book excerpt:

International Symposium on Chemistry and Physiology of Bile Pigments

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Publisher :
ISBN 13 :
Total Pages : 560 pages
Book Rating : 4.:/5 (327 download)

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Book Synopsis International Symposium on Chemistry and Physiology of Bile Pigments by : Paul D. Berk

Download or read book International Symposium on Chemistry and Physiology of Bile Pigments written by Paul D. Berk and published by . This book was released on 1977 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Annals of the New York Academy of Sciences

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Publisher :
ISBN 13 :
Total Pages : 748 pages
Book Rating : 4.X/5 (3 download)

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Book Synopsis Annals of the New York Academy of Sciences by : Thomas Lincoln Casey

Download or read book Annals of the New York Academy of Sciences written by Thomas Lincoln Casey and published by . This book was released on 1975 with total page 748 pages. Available in PDF, EPUB and Kindle. Book excerpt: Records of meetings 1808-1916 in v. 11-27.

Metabolic Pathways

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Publisher : Academic Press
ISBN 13 : 1483274527
Total Pages : 829 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Metabolic Pathways by : David M. Greenberg

Download or read book Metabolic Pathways written by David M. Greenberg and published by Academic Press. This book was released on 2014-05-12 with total page 829 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metabolic Pathways, Volume II focuses on the metabolism, biosynthesis, and catabolism of amino acids. The selection first offers information on nitrogen and carbon metabolism of amino acids. Discussions focus on amino acids linked with citric acid cycle, sulfur amino acids, proline and hydroxyproline, histidine, hydroxyamino acids, urea biosynthesis and related systems, and deamidation. The text then ponders on the biosynthesis of amino acids and related compounds and metabolism of sulfur-containing compounds. Topics include metabolism of methionine, biotin, biological importance of sulfur in animals, interconversions of glutamic acid, ornithine, and prolines, and biosynthesis of the branched-chain amino acids. The publication takes a look at the synthesis of proteins, purines and pyrimidines, and nucleotides and nucleosides, including the components of nucleotides, purine degradation, and incorporation of preformed purine compounds into nucleic acids. The selection is a valuable reference for researchers interested in the metabolism, catabolism, and biosynthesis of amino acids.

Biochemical Society Symposia

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Publisher :
ISBN 13 :
Total Pages : 194 pages
Book Rating : 4.:/5 (51 download)

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Book Synopsis Biochemical Society Symposia by : Biochemical Society (Great Britain). Symposium

Download or read book Biochemical Society Symposia written by Biochemical Society (Great Britain). Symposium and published by . This book was released on 1968 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Microsomes, Drug Oxidations and Chemical Carcinogenesis V1

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Publisher : Elsevier
ISBN 13 : 0323144098
Total Pages : 645 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis Microsomes, Drug Oxidations and Chemical Carcinogenesis V1 by : Minor Coon

Download or read book Microsomes, Drug Oxidations and Chemical Carcinogenesis V1 written by Minor Coon and published by Elsevier. This book was released on 2012-12-02 with total page 645 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microsomes, Drug Oxidations, and Chemical Carcinogenesis, Volume I, documents the proceedings of the 4th International Symposium on Microsomes and Drug Oxidations held in Ann Arbor, July 1979. The symposium reviewed progress in the understanding of scientific and biomedical problems from a biochemical, biophysical, pharmacological, and toxicological perspective. The book contains 117 contributions made by researchers at the symposium, which are organized into three sections. The papers in Section I focus on the chemical and physical characteristics of cytochrome P-450. Section II examines the mechanisms of action of cytochrome P-450 and related enzymes. The studies in Section III deal with the influence of membrane structure and protein synthesis on electron transfer components. This book seeks to aid future progress in understanding the complexities of metabolic transformations by these versatile enzyme systems that act on physiologically important lipids as well as on a wide array of foreign substances, including drugs, anesthetics, industrial chemicals, food additives, pesticides, carcinogens, and nonnutrient dietary chemicals.

The Porphyrin Handbook

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Publisher : Elsevier
ISBN 13 : 0080923860
Total Pages : 272 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis The Porphyrin Handbook by : Karl Kadish

Download or read book The Porphyrin Handbook written by Karl Kadish and published by Elsevier. This book was released on 2012-12-02 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Porphyrin Handbook, Volume 12: The Iron and Cobalt Pigments: Biosynthesis, Structure, and Degradation provides information pertinent to every aspect of the chemistry, synthesis, spectroscopy, and structure of phthalocyanines. This book presents the biochemical and clinical aspects of genetically transmitted or drug-induced diseases associated with errors in heme metabolism. Organized into eight chapters, this volume begins with an overview of the comparison of regulatory principles in animal and plant tetrapyrrole biosynthesis. This text then examines the biology and medical implications of porphyrin systems. Other chapters consider the transformation of hemes into bile pigments, the organic synthesis of bilins, and the pathways of degradation of chlorophyll in senescent plants. This book discusses as well the biosynthesis of porphyrins, vitamin B12, and chlorophylls. The final chapter deals with genome sequencing projects that provide sources of genes encoding the enzymes needed for the synthesis of the intermediates. This book is a valuable resource for research scientists, engineers, and clinicians.

Hepatotoxicology

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Publisher : CRC Press
ISBN 13 : 1000717577
Total Pages : 713 pages
Book Rating : 4.0/5 (7 download)

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Book Synopsis Hepatotoxicology by : Robert G. Meeks

Download or read book Hepatotoxicology written by Robert G. Meeks and published by CRC Press. This book was released on 2020-01-16 with total page 713 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is destined to serve as a classic reference source to which researchers can turn for a historical perspective and basic information on the physiology, biochemistry, and pathology of the liver. Major areas covered in the book include histological organization, classification of chemical-induced injury, stages of cellular injury, and xenobiotic metabolism. Chapters discussing the use of biochemical methods to determine liver damage, the effects of various chemical agents of the liver, and hepatocarcinogenesis are also presented. Toxicologists, physiologists, physicians, biochemists, industrial hygienists, and others interested in the effects of chemical agents on the structure and function will find this book to be an indispensable source of information.

Biosynthesis

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Publisher : Elsevier
ISBN 13 : 0323163378
Total Pages : 735 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis Biosynthesis by : I.C. Gunsalus

Download or read book Biosynthesis written by I.C. Gunsalus and published by Elsevier. This book was released on 1962-01-01 with total page 735 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biosynthesis