Polymeric Site Specific Pharmacotherapy

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Polymeric Site-specific Pharmacotherapy

Author : A. J. Domb
Publisher :
ISBN 13 :
Total Pages : 488 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Polymeric Site-specific Pharmacotherapy by : A. J. Domb

Download or read book Polymeric Site-specific Pharmacotherapy written by A. J. Domb and published by . This book was released on 1994-07-26 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polymeric Site-Specific Pharmacotherapy Edited by A. J. Domb The Hebrew University of Jerusalem, Israel This unique edited volume provides a comprehensive overview of site-specific drug delivery using polymeric implant devices. From the basic concept of localized drug delivery to major applications under active research, the subject is treated from a theoretical and practical viewpoint. Coverage includes the design, development and applications of polymeric devices, including suitable polymers, delivery systems and mechanisms of drug release. Recent advances and ongoing research are included and many subjects are reviewed here for the first time. Contributed to by an international team of acknowledged experts, this volume will have broad appeal amongst researchers, both in academia and industry, with an interest in polymer chemistry, biopolymers, pharmaceutical analysis, pharmacology, bioengineering, and medical and organic chemistry. Contents include: Implantable Biodegradable Polymers for Site-specific Drug Delivery A. J. Domb; Drug Release and Tissue Distribution from a Polymer Implant M. L. Radomsky; Modelling of Drug Delivery to Brain Tissue G. D. Lapin; Polymer Conjugated Macromolecular Drugs for Tumor Specific Targeting H. Maeda; Drug Delivery to the Brain H. Brem, K. A. Walter, R. J. Tamargo, A. Olivi and R. Langer; Microparticulate Systems for Site-specific Therapy — Bone Marrow Targeting C. J. Porter, M. C. Davies, S. S. Davies and L. Illum; Drug Delivery to the Lung K. C. Meyer, W. Auerbach and R. Auerbach; Polymers for the Prevention of Surgical Adhesions A. J. Domb and D. Wiseman

Applications of Polymers in Drug Delivery

Author : Ambikanandan Misra
Publisher : Elsevier
ISBN 13 : 0128226684
Total Pages : 594 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Applications of Polymers in Drug Delivery by : Ambikanandan Misra

Download or read book Applications of Polymers in Drug Delivery written by Ambikanandan Misra and published by Elsevier. This book was released on 2020-10-02 with total page 594 pages. Available in PDF, EPUB and Kindle. Book excerpt: Applications of Polymers in Drug Delivery, Second Edition, provides a comprehensive resource for anyone looking to understand how polymeric materials can be applied to current, new, and emerging drug delivery applications. Polymers play a crucial role in modulating drug delivery and have been fundamental in the successful development of many novel drug delivery systems. This book describes the development of polymeric systems, ranging from conventional dosage forms to the most recent smart systems. Regulatory and intellectual property aspects as well as the clinical applicability of polymeric drug delivery systems are also discussed. The chapters are organized by specific delivery route, offering methodical and detailed coverage throughout. This second edition has been thoroughly revised to include the latest developments in the field. This is an essential book for researchers, scientists, and advanced students, in polymer science, drug delivery, pharmacology/pharmaceuticals, materials science, tissue engineering, nanomedicine, chemistry, and biology. In industry, this book supports scientists, R&D, and other professionals, working on polymers for drug delivery applications. - Explains how polymers can be prepared and utilized for all major drug delivery routes - Presents the latest advances, including drug targeting, polymeric micelles and polymersomes, and the delivery of biologicals and nucleic acid therapeutics - Includes appendices with in-depth information on pharmaceutical properties of polymers and regulatory aspects

Nanoparticles in Pharmacotherapy

Author : Alexandru Mihai Grumezescu
Publisher : William Andrew
ISBN 13 : 0128165049
Total Pages : 632 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Nanoparticles in Pharmacotherapy by : Alexandru Mihai Grumezescu

Download or read book Nanoparticles in Pharmacotherapy written by Alexandru Mihai Grumezescu and published by William Andrew. This book was released on 2019-04-10 with total page 632 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanoparticles in Pharmacotherapy explores the most recent findings on how nanoparticles are used in pharmacotherapy, starting with their synthesis, characterization and current or potential uses. This book is a valuable resource of recent scientific progress that includes the most cutting-edge applications of nanoparticles in pharmacotherapy. It is ideal for researchers, medical doctors and those in academia.

Polymer Drugs in the Clinical Stage

Author : Hiroshi Maeda
Publisher : Springer Science & Business Media
ISBN 13 : 030647932X
Total Pages : 222 pages
Book Rating : 4.3/5 (64 download)

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Book Synopsis Polymer Drugs in the Clinical Stage by : Hiroshi Maeda

Download or read book Polymer Drugs in the Clinical Stage written by Hiroshi Maeda and published by Springer Science & Business Media. This book was released on 2006-04-11 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of the International Symposium on Polymer Therapeutics - Recent Progress in Clinics and Future Prospects, held July 13-14, 2001, in Nara, Japan. The technology of polymer science has developed considerably during the past half-century, and this volume describes some of the aspects of this technology that will have a great impact in the future. Among these advances, for example, are gene delivery to specific disease sites and carrier polymers that respond to a stimulus or particular environment. Cancer targeted drug delivery is another focused area of this volume because of the important nature of EPR-effect of polymer drugs in tumor. Included are discussions of as many examples as possible of polymer drugs that have achieved, or are close to clinical use. The concept of "Polymer drugs" here is limited to primarily injectable and water-soluble agents, although also covered are some drugs in micellar form or liposomes. This book is intended for students and researchers in the field of pharmacology who have particular interests in drug delivery, targeting, and formulation, as well as for clinicians such as oncologists who are interested in the field. People who work at regulatory agencies should also be aware such that drugs with great potential are being developed and will be beneficial to many patients, as well as to health insurance agencies because of improved cost effectiveness.

Polymeric Drugs and Drug Delivery Systems

Author : Raphael M. Ottenbrite
Publisher : CRC Press
ISBN 13 : 0429524579
Total Pages : 262 pages
Book Rating : 4.4/5 (295 download)

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Book Synopsis Polymeric Drugs and Drug Delivery Systems by : Raphael M. Ottenbrite

Download or read book Polymeric Drugs and Drug Delivery Systems written by Raphael M. Ottenbrite and published by CRC Press. This book was released on 2019-04-30 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polymeric materials are now playing an increasingly important role in pharmaceuticals, as well as in sensing devices, in situ prostheses and probes, and microparticle diagnostic agents. This new volume consists of twenty-two recent research-based reports on the developments in these areas of pharmaceutical and biomaterials technology. The reports w

Biodegradable Polymers in Clinical Use and Clinical Development

Author : Abraham J. Domb
Publisher : John Wiley & Sons
ISBN 13 : 1118015800
Total Pages : 594 pages
Book Rating : 4.1/5 (18 download)

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Book Synopsis Biodegradable Polymers in Clinical Use and Clinical Development by : Abraham J. Domb

Download or read book Biodegradable Polymers in Clinical Use and Clinical Development written by Abraham J. Domb and published by John Wiley & Sons. This book was released on 2011-05-12 with total page 594 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on biodegradable polymers that are already in clinical use or under clinical development. Synthetic and natural polymers will be included. This excludes polymers that have been investigated and did not reach clinical development. The purpose of this book is to provide updated status of the polymers that are clinical use and those that are now being developed for clinical use and hopefully will reach the clinic during the next 5 years. The book provides information that of interest to academics and practicing researchers including chemists, biologists and bioengineers and users: physicians, pharmacists.

Advanced Polymers in Medicine

Author : Francesco Puoci
Publisher : Springer
ISBN 13 : 3319124781
Total Pages : 538 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Advanced Polymers in Medicine by : Francesco Puoci

Download or read book Advanced Polymers in Medicine written by Francesco Puoci and published by Springer. This book was released on 2014-12-02 with total page 538 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book provides an up-to-date overview of the diverse medical applications of advanced polymers. The book opens by presenting important background information on polymer chemistry and physicochemical characterization of polymers. This serves as essential scientific support for the subsequent chapters, each of which is devoted to the applications of polymers in a particular medical specialty. The coverage is broad, encompassing orthopedics, ophthalmology, tissue engineering, surgery, dentistry, oncology, drug delivery, nephrology, wound dressing and healing, and cardiology. The development of polymers that enhance the biocompatibility of blood-contacting medical devices and the incorporation of polymers within biosensors are also addressed. This book is an excellent guide to the recent advances in polymeric biomaterials and bridges the gap between the research literature and standard textbooks on the applications of polymers in medicine.

Polymer-Drug Conjugates

Author : Jitender Madan
Publisher : Elsevier
ISBN 13 : 0323916902
Total Pages : 510 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Polymer-Drug Conjugates by : Jitender Madan

Download or read book Polymer-Drug Conjugates written by Jitender Madan and published by Elsevier. This book was released on 2023-07-05 with total page 510 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polymer-Drug Conjugates: Linker Chemistry, Protocols and Applications discusses important concepts, fundamentals and prospective applications of 'Linker Chemistry' in a clear-and-concise manner. The book provides vital information on chemical entities binding with the drug-polymer complex for targeted drug delivery systems. It highlights roles and significance, different classes and synthetic protocols as well as mechanisms of chemical bond formation in drug-polymer conjugation in drug delivery, also offering insights into the mechanism of polymer interaction with linker and drug molecules by biodegradable chemical bonding. The protocol of binding with drug molecules is clearly explained and justified with case studies, helping researchers and advanced students in the pharmaceutical sciences understand fundamentals involved and related aspects in molecule designing for effective therapeutic benefits. - Covers mechanism, protocol and therapeutic significance of Polymer-Drug Conjugates - Outlines updated methods and techniques to enumerate conjugation with related case studies - Includes comprehensive compilation of marketed and clinical trial drugs conjugated with polymers or linkers

Handbook of Polyester Drug Delivery Systems

Author : M. N. V. Ravi Kumar
Publisher : CRC Press
ISBN 13 : 1315341166
Total Pages : 401 pages
Book Rating : 4.3/5 (153 download)

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Book Synopsis Handbook of Polyester Drug Delivery Systems by : M. N. V. Ravi Kumar

Download or read book Handbook of Polyester Drug Delivery Systems written by M. N. V. Ravi Kumar and published by CRC Press. This book was released on 2017-03-27 with total page 401 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the quest for innovative drug delivery systems attempting to meet the unmet needs in pharmaceutical space, research has taken a much more complicated path that poses a significant challenge for translation. Despite the progress made with novel materials, polyesters still remain at the helm of drug delivery technologies. This book provides a single source of reference of polyester drug delivery systems that covers a broad spectrum of materials design, manufacturing techniques, and applications.

Targeted Delivery of Small and Macromolecular Drugs

Author : Ajit S. Narang
Publisher : CRC Press
ISBN 13 : 1420087738
Total Pages : 632 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Targeted Delivery of Small and Macromolecular Drugs by : Ajit S. Narang

Download or read book Targeted Delivery of Small and Macromolecular Drugs written by Ajit S. Narang and published by CRC Press. This book was released on 2010-05-12 with total page 632 pages. Available in PDF, EPUB and Kindle. Book excerpt: Site-specific drug delivery and targeting attracts much research interest from both academia and industry, but because of the many challenges faced in the development of these systems, only a handful of targeted therapies have successfully made it into clinical practice. Focusing on the delivery technologies that utilize both systemic and local rou

Recent Advances in Novel Drug Carrier Systems

Author : Ali Demir Sezer
Publisher : BoD – Books on Demand
ISBN 13 : 9535108107
Total Pages : 516 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Recent Advances in Novel Drug Carrier Systems by : Ali Demir Sezer

Download or read book Recent Advances in Novel Drug Carrier Systems written by Ali Demir Sezer and published by BoD – Books on Demand. This book was released on 2012-10-31 with total page 516 pages. Available in PDF, EPUB and Kindle. Book excerpt: This contribution book collects reviews and original articles from eminent experts working in the interdisciplinary arena of novel drug delivery systems and their uses. From their direct and recent experience, the readers can achieve a wide vision on the new and ongoing potentialities of different drug delivery systems. Since the advent of analytical techniques and capabilities to measure particle sizes in nanometer ranges, there has been tremendous interest in the use of nanoparticles for more efficient methods of drug delivery. On the other hand, this reference discusses advances in the design, optimization, and adaptation of gene delivery systems for the treatment of cancer, cardiovascular, pulmonary, genetic, and infectious diseases, and considers assessment and review procedures involved in the development of gene-based pharmaceuticals.

Advanced Drug Delivery Systems in the Management of Cancer

Author : Kamal Dua
Publisher : Elsevier
ISBN 13 : 0323900798
Total Pages : 574 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Advanced Drug Delivery Systems in the Management of Cancer by : Kamal Dua

Download or read book Advanced Drug Delivery Systems in the Management of Cancer written by Kamal Dua and published by Elsevier. This book was released on 2021-06-24 with total page 574 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advanced Drug Delivery Systems in the Management of Cancer discusses recent developments in nanomedicine and nano-based drug delivery systems used in the treatment of cancers affecting the blood, lungs, brain, and kidneys. The research presented in this book includes international collaborations in the area of novel drug delivery for the treatment of cancer. Cancer therapy remains one of the greatest challenges in modern medicine, as successful treatment requires the elimination of malignant cells that are closely related to normal cells within the body. Advanced drug delivery systems are carriers for a wide range of pharmacotherapies used in many applications, including cancer treatment. The use of such carrier systems in cancer treatment is growing rapidly as they help overcome the limitations associated with conventional drug delivery systems. Some of the conventional limitations that these advanced drug delivery systems help overcome include nonspecific targeting, systemic toxicity, poor oral bioavailability, reduced efficacy, and low therapeutic index. This book begins with a brief introduction to cancer biology. This is followed by an overview of the current landscape in pharmacotherapy for the cancer management. The need for advanced drug delivery systems in oncology and cancer treatment is established, and the systems that can be used for several specific cancers are discussed. Several chapters of the book are devoted to discussing the latest technologies and advances in nanotechnology. These include practical solutions on how to design a more effective nanocarrier for the drugs used in cancer therapeutics. Each chapter is written with the goal of informing readers about the latest advancements in drug delivery system technologies while reinforcing understanding through various detailed tables, figures, and illustrations. Advanced Drug Delivery Systems in the Management of Cancer is a valuable resource for anyone working in the fields of cancer biology and drug delivery, whether in academia, research, or industry. The book will be especially useful for researchers in drug formulation and drug delivery as well as for biological and translational researchers working in the field of cancer. - Presents an overview of the recent perspectives and challenges within the management and diagnosis of cancer - Provides insights into how advanced drug delivery systems can effectively be used in the management of a wide range of cancers - Includes up-to-date information on diagnostic methods and treatment strategies using controlled drug delivery systems

Providing Pharmacological Access to the Brain

Author : Thomas R. Flanagan
Publisher : Academic Press
ISBN 13 : 1483288358
Total Pages : 531 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Providing Pharmacological Access to the Brain by : Thomas R. Flanagan

Download or read book Providing Pharmacological Access to the Brain written by Thomas R. Flanagan and published by Academic Press. This book was released on 2013-10-22 with total page 531 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume focuses on contemporary approaches for delivering experimental and therapeutic agents into the brain. The contributions provide methodological details that are typically not available in the literature. Subtleties and shortcuts critical to each procedure are included to facilitate their use by both the experienced researcher and novice.Highlights* Polymeric, cellular, and molecular drug delivery* Neuropharmacology* Blood-brain barrier* Central nervous system

Drug Delivery in Oncology

Author : Felix Kratz
Publisher : John Wiley & Sons
ISBN 13 : 3527647759
Total Pages : 1828 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Drug Delivery in Oncology by : Felix Kratz

Download or read book Drug Delivery in Oncology written by Felix Kratz and published by John Wiley & Sons. This book was released on 2013-09-30 with total page 1828 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this first authoritative overview on modern cancer chemotherapy 121 international specialists have contributed their experience and recent data for what is likely to become the gold standard in the field. The authors summarize knowledge gained over the past decade, from basic concepts to successful applications in the clinic, covering active and passive targeting strategies as well as tissue-specific approaches. All current and future targeted delivery systems are discussed, from ligand-based to antibody-based polymer-based systems, right up to micro- and nanoparticulate systems. A special section covers the delivery of nucleic acid therapeutics, such as siRNA, miRNA and antisense nucleotides. In each case, a description of the basic technique is followed by a discussion of the latest preclinical and clinical developments in the field. By virtue of its clear and didactic structure, rich illustrative material and summary chapters, this handbook and ready reference enables the efficient transfer of knowledge between different disciplines, from basic research to the clinician and vice versa. It is equally well suited for professionals, researchers and students in medical oncology and cancer biology, and is also excellent for teaching medical students the foundations of 21st century cancer chemotherapy.

Smart Polymers

Author : Igor Galaev
Publisher : CRC Press
ISBN 13 : 1439832374
Total Pages : 492 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Smart Polymers by : Igor Galaev

Download or read book Smart Polymers written by Igor Galaev and published by CRC Press. This book was released on 2007-07-25 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first book to tackle the application of smart polymers in bioseparation and bioprocessing, Smart Polymers: Applications in Biotechnology and Biomedicine broke new ground in this challenging field. Completely revised, updated, and following in the footsteps of its predecessor, the second edition is poised to take its place as a premier reference

Handbook of Biodegradable Polymers

Author : Abraham J. Domb
Publisher : CRC Press
ISBN 13 : 9781420049367
Total Pages : 548 pages
Book Rating : 4.0/5 (493 download)

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Book Synopsis Handbook of Biodegradable Polymers by : Abraham J. Domb

Download or read book Handbook of Biodegradable Polymers written by Abraham J. Domb and published by CRC Press. This book was released on 1998-02-04 with total page 548 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Biodegradable Polymers, the seventh volume in the Drug Delivery and Targeting book series, provides a source manual for synthetic procedures, properties and applications of bioerodible polymers. The authors describe widely available materials such as polyactides, collagen and gelatin, as well as polymers of emerging importance, such as the genetically-engineered and elastin-based polymers which are either proprietary or in early stages of development. Section I addresses synthetic absorbable polymers, and Section 2 profiles natural, semi-synthetic and biosynthetic polymers. Section 3 discusses the surface characterization of degradable polymers, the modeling of biodegradation and non-medical polymers. This book is ideal for researchers from academia and industry as well as chemists, pharmacists and physicians who deal with biopolymers, drug delivery and targeting, bioengineering and implantable devices.

Handbook of Nonmedical Applications of Liposomes

Author : Yechezkel Barenholz
Publisher : CRC Press
ISBN 13 : 1351089625
Total Pages : 712 pages
Book Rating : 4.3/5 (51 download)

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Book Synopsis Handbook of Nonmedical Applications of Liposomes by : Yechezkel Barenholz

Download or read book Handbook of Nonmedical Applications of Liposomes written by Yechezkel Barenholz and published by CRC Press. This book was released on 2018-01-31 with total page 712 pages. Available in PDF, EPUB and Kindle. Book excerpt: Liposomes have become an important model in fundamental biomembrane research, including biophysical, biochemical, and cell biological studies of membranes and cell function. They are thoroughly studied in several applications, such as drug delivery systems in medical applications and as controlled release systems, microencapsulating media, signal carriers, support matrices, and solubilizers in other applications. While medical applications have been extensively reviewed in recent literature, there is a need for easily accessible information on applications for liposomes beyond pharmacology and medicine. The Handbook of Nonmedical Applications of Liposomes fills this void. This unique new handbook series presents recent developments in the use of liposomes in many scientific disciplines, from studies on the origin of life, protein function, and vesicle shapes, to applications in cosmetics, diagnostics, ecology, bioreclamation, and the food industry. In these volumes many of the top experts contribute extensive reviews of their work.