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Author :
Publisher :
ISBN 13 :
Total Pages : 852 pages
Book Rating : 4.3/5 (129 download)
Download or read book Energy Research Abstracts written by and published by . This book was released on 1990 with total page 852 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Kenneth Kam-Wing Lo
Publisher : Springer
ISBN 13 : 3662467186
Total Pages : 266 pages
Book Rating : 4.6/5 (624 download)
Download or read book Luminescent and Photoactive Transition Metal Complexes as Biomolecular Probes and Cellular Reagents written by Kenneth Kam-Wing Lo and published by Springer. This book was released on 2015-06-30 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: The series Structure and Bonding publishes critical reviews on topics of research concerned with chemical structure and bonding. The scope of the series spans the entire Periodic Table and addresses structure and bonding issues associated with all of the elements. It also focuses attention on new and developing areas of modern structural and theoretical chemistry such as nanostructures, molecular electronics, designed molecular solids, surfaces, metal clusters and supramolecular structures. Physical and spectroscopic techniques used to determine, examine and model structures fall within the purview of Structure and Bonding to the extent that the focus is on the scientific results obtained and not on specialist information concerning the techniques themselves. Issues associated with the development of bonding models and generalizations that illuminate the reactivity pathways and rates of chemical processes are also relevant. The individual volumes in the series are thematic. The goal of each volume is to give the reader, whether at a university or in industry, a comprehensive overview of an area where new insights are emerging that are of interest to a larger scientific audience. Thus each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years should be presented using selected examples to illustrate the principles discussed. A description of the physical basis of the experimental techniques that have been used to provide the primary data may also be appropriate, if it has not been covered in detail elsewhere. The coverage need not be exhaustive in data, but should rather be conceptual, concentrating on the new principles being developed that will allow the reader, who is not a specialist in the area covered, to understand the data presented. Discussion of possible future research directions in the area is welcomed. Review articles for the individual volumes are invited by the volume editors. Readership: research scientists at universities or in industry, graduate students Special offer For all customers who have a standing order to the print version of Structure and Bonding, we offer free access to the electronic volumes of the Series published in the current year via SpringerLink.
Author : Janice Aldrich-Wright
Publisher : Springer
ISBN 13 : 3211990798
Total Pages : 449 pages
Book Rating : 4.2/5 (119 download)
Download or read book Metallointercalators written by Janice Aldrich-Wright and published by Springer. This book was released on 2011-04-06 with total page 449 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive treatment of the characterisation techniques used in investigating inorganic and organic molecules that interact with biomolecules is presented to the reader in a clear fashion. The work consists of two parts: (i) synthetic aspects of metallointercalators along with targeting and improving transport and (ii) the various techniques that are used for probing their interactions, such as; DNA-NMR, PGSE-NMR, DNA ESI-MS, Linear and Circular Dichroism, Fluorescence Spectroscopy, Confocal Microscopy, Viscosity, TGA and dialysis, Microarrays, biological analysis. Chapters are devoted to the synthesis and the techniques used to study the interactions of inorganic complexes with biomolecules. Considerably detailed examples are used to help illustrate the application of these techniques. This book is a useful resource for an array of inorganic and organic advanced undergraduate and graduate courses and for researchers in drug discovery.
Author :
Publisher :
ISBN 13 :
Total Pages : 784 pages
Book Rating : 4.3/5 (91 download)
Download or read book American Doctoral Dissertations written by and published by . This book was released on 1998 with total page 784 pages. Available in PDF, EPUB and Kindle. Book excerpt:
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ISBN 13 :
Total Pages : 846 pages
Book Rating : 4.F/5 ( download)
Download or read book Dissertation Abstracts International written by and published by . This book was released on 2006 with total page 846 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : American Chemical Society. Committee on Professional Training
Publisher :
ISBN 13 :
Total Pages : 1646 pages
Book Rating : 4.0/5 ( download)
Download or read book Faculties, Publications, and Doctoral Theses in Chemistry and Chemical Engineering at United States Universities written by American Chemical Society. Committee on Professional Training and published by . This book was released on 1991 with total page 1646 pages. Available in PDF, EPUB and Kindle. Book excerpt:
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ISBN 13 :
Total Pages : 1530 pages
Book Rating : 4.:/5 (319 download)
Download or read book Government Reports Announcements & Index written by and published by . This book was released on 1991 with total page 1530 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Maria Contel
Publisher : MDPI
ISBN 13 : 3039213156
Total Pages : 204 pages
Book Rating : 4.0/5 (392 download)
Download or read book Unconventional Anticancer Metallodrugs and Strategies to Improve their Pharmacological Profile written by Maria Contel and published by MDPI. This book was released on 2019-10-01 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt: For the past 40 years, metal-based drugs have been widely used for the treatment of cancer. Cisplatin and follow-up drugs carboplatin (ParaplatinTM) and oxaliplatin (EloxatinTM) have been the gold standard for metallodrugs in clinical settings as antineoplastic agents. While effective, these drugs (either alone or in combination therapy) have faced a number of clinical challenges resulting from their limited spectrum of activity, high toxicity leading to significant side effects, resistance, poor water solubility, low bioavailability and short circulating time. In the past 10 years, various unconventional non-platinum metal-based agents have emerged as a potential alternative for cancer treatment. These compounds are highly effective and selective in cancers resistant to cisplatin and other chemotherapeutic agents. Research in this area has recently exploded with a relevant number of patents and clinical trials, in addition to reports in scientific journals. Furthermore, in parallel to the synthesis of coordination and organometallic compounds comprising many different metals and unconventional platinum-based derivatives, researchers are focused on optimizing mechanistic and pharmacological features of promising drug candidates. This Special Issue aims to highlight the latest advances in anticancer metallodrugs with a focus on unconventional anticancer agents, as well as novel activation, targeting and delivery strategies aimed at improving their pharmacological profile.
Author : Society of Photo-optical Instrumentation Engineers
Publisher : SPIE-International Society for Optical Engineering
ISBN 13 :
Total Pages : 298 pages
Book Rating : 4.3/5 (91 download)
Download or read book Proceedings of Advances in Optical Biophysics written by Society of Photo-optical Instrumentation Engineers and published by SPIE-International Society for Optical Engineering. This book was released on 1998 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : D. Michael P. Mingos
Publisher : Springer
ISBN 13 : 3319351389
Total Pages : 350 pages
Book Rating : 4.3/5 (193 download)
Download or read book 50 Years of Structure and Bonding – The Anniversary Volume written by D. Michael P. Mingos and published by Springer. This book was released on 2016-10-06 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemical structure and bonding. The scope of the series spans the entire Periodic Table and addresses structure and bonding issues associated with all of the elements. It also focuses attention on new and developing areas of modern structural and theoretical chemistry such as nanostructures, molecular electronics, designed molecular solids, surfaces, metal clusters and supramolecular structures. Physical and spectroscopic techniques used to determine, examine and model structures fall within the purview of Structure and Bonding to the extent that the focus is on the scientific results obtained and not on specialist information concerning the techniques themselves. Issues associated with the development of bonding models and generalizations that illuminate the reactivity pathways and rates of chemical processes are also relevant. The individual volumes in the series are thematic. The goal of each volume is to give the reader, whether at a university or in industry, a comprehensive overview of an area where new insights are emerging that are of interest to a larger scientific audience. Thus each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years should be presented using selected examples to illustrate the principles discussed. A description of the physical basis of the experimental techniques that have been used to provide the primary data may also be appropriate, if it has not been covered in detail elsewhere. The coverage need not be exhaustive in data, but should rather be conceptual, concentrating on the new principles being developed that will allow the reader, who is not a specialist in the area covered, to understand the data presented. Discussion of possible future research directions in the area is welcomed. Review articles for the individual volumes are invited by the volume editors.
Author : Toshikazu Hirao
Publisher : Elsevier
ISBN 13 : 0128141980
Total Pages : 474 pages
Book Rating : 4.1/5 (281 download)
Download or read book Advances in Bioorganometallic Chemistry written by Toshikazu Hirao and published by Elsevier. This book was released on 2018-11-30 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Bioorganometallic Chemistry examines the synthesis, structure and reactivity of bioorganometallics, their pharmaceutical applications, hydrogenase, vitamin B12-like systems, and metalloproteins. It is written by the top researchers in the field and compiled by editors Toshikazu Hirao and Toshiyuki Moriuchi. Developments in this new field of bioorganometallic chemistry, a hybrid between biology and organometallic chemistry, happen very quickly and this comprehensive reference offers the latest research and findings in the field. The book features a discussion of the synthesis, structure, and reactivity of bioorganometallics, and an examination of hydrogenase-like systems, which were designed to demonstrate catalytic activities and functional properties. Advances in Bioorganometallic Chemistry also includes a discussion of bioorganometallics as they relate to medicinal chemistry, specifically applications of metalloproteins, metalloenzymes, and applications in bioimaging. The book concludes with coverage of vitamin B12-like systems, including the latest developments in derivatives designed to perform bio-inspired catalytic reactions. This work is a valuable resource for chemists working in organometallic chemistry and biology, including biochemists, bioorganic chemists, bioinorganic chemists, as well as pharmaceutical scientists, medicinal chemists, and students studying in these areas. Representative authors: R. H. Fish, T. Moriuchi, T. Hirao, H.-B. Kraatz, H. Takaya, T. P. Curran, G. van Koten. E. Rosenberg, J. M. Lynam, C. G. Hartinger, U. Schatzschneider, G. S. Smith, R. Alberto, S. Takenaka, T. Ihara, T. Hayashi, T. Ueno, P. Schollhammer, Y. Shomura, Y. Hisaeda, H. Shimakoshi, B. Kräutler - Provides a balanced overview of the latest research in the field of bioorganometallic chemistry, drawing together the top researchers from around the world - Covers topics in the areas of synthesis, reactivity, hydrogenase-like systems, medicinal chemistry, applications of metalloproteins, metalloenzymes, and applications in bioimaging
Author : Shahid Ul Islam
Publisher : John Wiley & Sons
ISBN 13 : 1119640423
Total Pages : 432 pages
Book Rating : 4.1/5 (196 download)
Download or read book Advances in Metallodrugs written by Shahid Ul Islam and published by John Wiley & Sons. This book was released on 2020-07-08 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is organized into 12 important chapters that focus on the progress made by metal-based drugs as anticancer, antibacterial, antiviral, anti-inflammatory, and anti-neurodegenerative agents, as well as highlights the application areas of newly discovered metallodrugs. It can prove beneficial for researchers, investigators and scientists whose work involves inorganic and coordination chemistry, medical science, pharmacy, biotechnology and biomedical engineering.
Author : Eli Zysman-Colman
Publisher : John Wiley & Sons
ISBN 13 : 1119007151
Total Pages : 736 pages
Book Rating : 4.1/5 (19 download)
Download or read book Iridium(III) in Optoelectronic and Photonics Applications written by Eli Zysman-Colman and published by John Wiley & Sons. This book was released on 2017-03-07 with total page 736 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fundamental photophysical properties of iridium(III) materials make this class of materials the pre-eminent transition metal complex for use in optoelectronic applications. Iridium(III) in Optoelectronic and Photonics Applications represents the definitive account of photoactive iridium complexes and their use across a wide variety of applications. This two-volume set begins with an overview of the synthesis of these complexes and discusses their photophysical properties. The text highlights not only mononuclear complexes but also the properties of multinuclear and polymeric iridium-based materials and the assembly of iridium complexes into larger supramolecular architectures such as MOFs and soft materials. Chapters devoted to the use of these iridium-based materials in diverse optoelectronic applications follow, including: electroluminescent devices such as organic light emitting diodes (OLEDs) and light-emitting electrochemical cells (LEECs); electrochemiluminescence (ECL); bioimaging; sensing; light harvesting in the context of solar cell applications; in photoredox catalysis and as components for solar fuels. Although primarily targeting a chemistry audience, the wide applicability of these compounds transcends traditional disciplines, making this text also of use to physicists, materials scientists or biologists who have interests in these areas.
Author : Tim Storr
Publisher : John Wiley & Sons
ISBN 13 : 1118697898
Total Pages : 650 pages
Book Rating : 4.1/5 (186 download)
Download or read book Ligand Design in Medicinal Inorganic Chemistry written by Tim Storr and published by John Wiley & Sons. This book was released on 2014-06-12 with total page 650 pages. Available in PDF, EPUB and Kindle. Book excerpt: Increasing the potency of therapeutic compounds, while limiting side-effects, is a common goal in medicinal chemistry. Ligands that effectively bind metal ions and also include specific features to enhance targeting, reporting, and overall efficacy are driving innovation in areas of disease diagnosis and therapy. Ligand Design in Medicinal Inorganic Chemistry presents the state-of-the-art in ligand design for medicinal inorganic chemistry applications. Each individual chapter describes and explores the application of compounds that either target a disease site, or are activated by a disease-specific biological process. Ligand design is discussed in the following areas: Platinum, Ruthenium, and Gold-containing anticancer agents Emissive metal-based optical probes Metal-based antimalarial agents Metal overload disorders Modulation of metal-protein interactions in neurodegenerative diseases Photoactivatable metal complexes and their use in biology and medicine Radiodiagnostic agents and Magnetic Resonance Imaging (MRI) agents Carbohydrate-containing ligands and Schiff-base ligands in Medicinal Inorganic Chemistry Metalloprotein inhibitors Ligand Design in Medicinal Inorganic Chemistry provides graduate students, industrial chemists and academic researchers with a launching pad for new research in medicinal chemistry.
Author : Taotao Zou
Publisher : Springer
ISBN 13 : 9811006571
Total Pages : 175 pages
Book Rating : 4.8/5 (11 download)
Download or read book Anti-Cancer N-Heterocyclic Carbene Complexes of Gold(III), Gold(I) and Platinum(II) written by Taotao Zou and published by Springer. This book was released on 2016-02-19 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thesis focuses on the development of gold- and non-classical platinum-based anti-cancer agents that display distinctively different anti-cancer mechanisms compared to the commonly used cisplatin. These metal complexes contain N-heterocyclic carbene (NHC) ligands which are able to form strong M-C(NHC) bonds, conferring high stability and favorable lipophilicity, reactivity and binding specificity of metal complexes on biomolecules. The author demonstrates significant advances made in anti-cancer gold(III), gold(I) and platinum(II) complexes. Detailed chemical synthesis, in vitro and/or in vivo anti-cancer activities are clearly presented including: (i) a class of Au(III) complexes containing a highly fluorescent N^N^N ligand and NHC ligand that simultaneously act as fluorescent thiol “switch-on” probes and anti-cancer agents; (ii) a dinuclear gold(I) complex with a mixed diphosphine and bis(NHC) ligand displaying favorable stability and showing significant inhibition of tumor growth in two independent mice models with no observable side effects; and (iii) a panel of stable luminescent cyclometalated platinum(II) complexes exhibiting high specificity to localize to the endoplasmic reticulum (ER) domain, inducing ER stress and cell apoptosis. These works highlight the clinical potential that gold and platinum complexes offer for cancer treatment.
Author : Dönüs Tuncel
Publisher : Royal Society of Chemistry
ISBN 13 : 1788018753
Total Pages : 268 pages
Book Rating : 4.7/5 (88 download)
Download or read book Cucurbituril-based Functional Materials written by Dönüs Tuncel and published by Royal Society of Chemistry. This book was released on 2019-08-28 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: Smart materials constructed through supramolecular assemblies have been receiving considerable attention because of their potential applications, which include self-healing materials, energy storage, photonic devices, sensors and theranostics. Host–guest chemistry of various macrocyclic receptors with organic guests provides a unique way to control tailor-made nanoarchitectures for the formation of pre-designed functional materials. Cucurbituril-based Function Materials provides an overview of this fascinating macrocycle, cucurbituril (CB) homologues and derivatives-based supramolecular nanostructured materials. Chapters cover the synthesis, properties and application of CB-based smart materials and nanostructures. With contributions from key researchers, this book will be of interest to students and researchers working in materials science, as well as those working on cucurbituril-based materials in organic and physical chemistry.
Author :
Publisher :
ISBN 13 :
Total Pages : 1616 pages
Book Rating : 4.:/5 (319 download)
Download or read book Index Medicus written by and published by . This book was released on 2003 with total page 1616 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
