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Physiology And Pharmacology Of The Brain Stem
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Book Synopsis Physiology and Pharmacology of the Brain Stem by : Shih-Chun Wang
Download or read book Physiology and Pharmacology of the Brain Stem written by Shih-Chun Wang and published by Blackwell/Futura. This book was released on 1980 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Pharmacology and Physiology of the Nervous System; Report, November 18-December 13, 1958 by : United States. Medical Exchange Mission to the USSR.
Download or read book Pharmacology and Physiology of the Nervous System; Report, November 18-December 13, 1958 written by United States. Medical Exchange Mission to the USSR. and published by . This book was released on 1960 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Drug Delivery to the Brain by : Elizabeth C.M. de Lange
Download or read book Drug Delivery to the Brain written by Elizabeth C.M. de Lange and published by Springer Nature. This book was released on 2022-05-24 with total page 810 pages. Available in PDF, EPUB and Kindle. Book excerpt: The development of new CNS drugs is notoriously difficult. Drugs must reach CNS target sites for action and these sites are protected by a number of barriers, the most important being the blood–brain barrier (BBB). Many factors are therefore critical to consider for CNS drug delivery, e.g. active/passive transport across the BBB, intra-brain distribution, and central/systemic pharmacokinetics, to name a few. Neurological disease and trauma conditions add further complexity because CNS barriers, drug distribution and pharmacokinetics are dynamic and often changed by disease/trauma. Knowledge of all these factors and their interplay in different conditions is of utmost importance for proper CNS drug development and disease treatment. In recent years much information has become available for a better understanding of the many factors important for CNS drug delivery and how they interact to affect drug action. This book describes small and large drug delivery to the brain with an emphasis on the physiology of the BBB and the principles and concepts for drug delivery across the BBB and distribution within the brain. It contains methods descriptions for studying drug delivery, routes and approaches of administering drugs into the brain, the influence of disease, drug industry perspectives, and a primer on neuroanatomy and physiological considerations written specifically for drug delivery scientists. Therewith, it contributes to an in-depth understanding of the interplay between brain (patho)-physiology and drug characteristics. Furthermore, the content is designed to be both cutting-edge and educational, so that the book can be used in high-level training of academic and industry scientists with full references to original publications.
Book Synopsis The Nervous System by : Walter S. Root
Download or read book The Nervous System written by Walter S. Root and published by Elsevier. This book was released on 2013-10-22 with total page 720 pages. Available in PDF, EPUB and Kindle. Book excerpt: Physiological Pharmacology: A Comprehensive Treatise, Volume I: The Nervous System — Part A, Central Nervous System Drugs focuses on the influence of drugs on the functions of the central nervous system. The selection first offers information on absorption, distribution, and elimination and effects upon physiological systems. Discussions focus on factors that disturb normal sequence of uptake and elimination of volatile drugs; variations in distribution due to systemic effects of anesthetics; factors influencing the uptake of gases by tissues; and theories of general anesthesia. The book also ponders on alcohols, including alcohols acting on the central nervous system; effect of alcohols on and outside the central nervous system; and synergisms and antagonisms between alcohols and other drugs. The publication takes a look at sedatives and hypnotics, effects upon physiological systems, and analgesics and antipyretic drugs. The text also examines non-narcotic analgesics, tranquilizers, and diphenylmethane derivatives. The selection is a vital source of data for readers interested in the effects of drugs on the central nervous system.
Book Synopsis Physiology, Pharmacology and Pathology of the Blood-Brain Barrier by : Zameel Cader
Download or read book Physiology, Pharmacology and Pathology of the Blood-Brain Barrier written by Zameel Cader and published by Springer Nature. This book was released on 2022-06-13 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a comprehensive collection of current knowledge and leading research about the blood-brain barrier. The chapters are organized in four main parts providing basic information and novel insights about the physiology of the blood-brain barrier, the challenges related to finding and developing drugs crossing the blood-brain barrier, experimental methods to study the blood-brain barrier and the role of the blood-brain barrier in disease mechanisms and its consequences for drug development. In the first part the readers will discover the structure, function and developmental aspects of the blood-brain barrier and gain novel insights into the complexity and functionality of the neurovascular unit and energy metabolism of brain endothelial cells. Chapters of the second part focus on translational challenges from the bench to the bedside in CNS drug development, shed light on the importance to understand the brain distribution of drugs related to their efficacy, elaborate on general pharmacokinetic considerations for CNS drugs and introduce current and novel drug delivery strategies to overcome the blood-brain barrier. The experimental part of the book covers mathematical and in vitro models as well as animal and human methods in blood-brain barrier research. Specific emphasis is set on the description of the methods, the role of species differences for data interpretation, novel human models based on stem cells with the potential for personalized medicine and technical considerations and tips helpful for readers interested in working with these models. In the fourth part particular attentions is given to the blood-brain barrier, its changes and participation during disease progression. Chapters summarize alterations of the blood-brain barrier that are present in common disorders such as Alzheimer’s disease, multiple sclerosis, stroke, traumatic brain injury, epilepsy and brain tumors. Present therapies will be discussed and the consequences for novel treatment approaches that need to bypass the blood-brain-barrier will be explored. In addition, experts discuss the question in how far changes at the blood-brain barrier are causally linked to disease progressions and consequently could serve as therapeutic targets. This collection is designed to appeal to a wide readership from students through basic and applied scientist to pharmacologists, medical doctors and stakeholders from the pharmaceutical industry and regulatory affairs. Due its comprehensive content the book has the potential to become a standard work in the field of blood-brain barrier research.
Book Synopsis Neurophysiology: Brain-Stem Function and Control by : Rosalyn Pryor
Download or read book Neurophysiology: Brain-Stem Function and Control written by Rosalyn Pryor and published by American Medical Publishers. This book was released on 2023-09-26 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The area of medicine which focuses on the diagnosis and monitoring of neurological diseases through the measurement and evaluation of nervous system function is known as neurophysiology. Brain-stem is an important part of the nervous system which connects the brain to the spinal cord. There are majorly three parts of the brain-stem, which includes the medulla oblongata, the midbrain and the pons and sometimes the diencephalon. The brain-stem plays a crucial role in conduction. This involves relaying the information from the body to the cerebellum and cerebrum, which pass through the brainstem. It also has integrative functions which play an integral role in respiratory control, alertness, pain sensitivity control, cardiovascular system control, consciousness and awareness. This book is a compilation of chapters that discuss the most vital concepts and emerging trends in the field of neurophysiology. It provides comprehensive insights into brain-stem function and control. This book will prove to be immensely beneficial to students and researchers in this field.
Book Synopsis Pharmacology and physiology of thereticular Formation by :
Download or read book Pharmacology and physiology of thereticular Formation written by and published by Elsevier. This book was released on 1967-01-01 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmacology and physiology of thereticular Formation
Book Synopsis Physiological Pharmacology: Autonomic nervous system drugs by : Walter Stanton Root
Download or read book Physiological Pharmacology: Autonomic nervous system drugs written by Walter Stanton Root and published by . This book was released on 1963 with total page 730 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Handbook of Drug and Chemical Stimulation of the Brain: Behavioral, Pharmacological, and Physiological Aspects by : R. D. Myers
Download or read book Handbook of Drug and Chemical Stimulation of the Brain: Behavioral, Pharmacological, and Physiological Aspects written by R. D. Myers and published by . This book was released on 1974 with total page 794 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Central Regulation of Autonomic Functions by : Arthur D. Loewy
Download or read book Central Regulation of Autonomic Functions written by Arthur D. Loewy and published by Oxford University Press. This book was released on 1990-06-07 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique text relates the dramatic advances of modern neurobiology to our understanding of the structure and function of the autonomic nervous system, providing a clear view of the central neuronal components involved in autonomic control. The scope is wide, ranging from anatomical pathways and molecular pharmacology to the perceptual qualities of autonomic sensation and their potential in modifying behavior. Essential background information is reviewed and the most recent research discussed in a readable, informative manner. The text is richly illustrated. The first six chapters offer a comprehensive review of the system's anatomy, physiology, and pharmacology, emphasizing the organization and control of the autonomic preganglionic neurons and the complexity of central pathways. Later chapters review the autonomic control of cardiovascular, sexual, urinary, endocrine, and other functions. Written by an international group of distinguished scientists, this work is a valuable resource for clinicians, scientists, and graduate students in the fields of anatomy, physiology, pharmacology, and neuroscience.
Book Synopsis The Pharmacology of Synapses by : J. W. Phillis
Download or read book The Pharmacology of Synapses written by J. W. Phillis and published by Pergamon. This book was released on 1970 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Regulatory Functions of the CNS by : János Szentágothai
Download or read book Regulatory Functions of the CNS written by János Szentágothai and published by . This book was released on 1981 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Brain and Its Physiology by : Daniel Noble
Download or read book The Brain and Its Physiology written by Daniel Noble and published by . This book was released on 1995 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Central Neural Mechanisms in Cardiovascular Regulation by : KUNOS
Download or read book Central Neural Mechanisms in Cardiovascular Regulation written by KUNOS and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: High blood pressure disease is one of the most prevalent pathological conditions in modem society with potentially serious consequences. During the last two decades major progress has been made in the development of rational approaches to the treatment of high blood pressure. A key factor in this progress has been an increase in our understanding of how the brain controls blood pressure. The chapters in the present book, together with those in a previous volume, provide a broad overview of recent progress in our knowledge of the central neural mechanisms involved in the regulation of the cardiovascular system. It is our hope that these essays by leading experts in the field will not only provide a useful source of information, but will also stimulate inquiry leading to new discoveries in this critically important field of research. George Kunos John Ciriello vii List of Contributors Jeffrey J. Anderson, Department of Pharmacology and Toxicology, Indiana University School of Medicine, Indianapolis, Indiana 46208, USA Katsuyuki Ando, Fourth Department of Internal Medicine, University of Tokyo School of Medicine, Tokyo 112, Japan Jaideep S. Bains, Department of Physiology, Queen's University, Kingston, Ontario, Canada K7L 3N6 Kathleen H. Berecek, Department of Physiology and Biophysics and the Vascular Biology and Hypertension Program, The University of Alabama at Birmingham, Birmingham, Alabama 35294, USA Vernon S. Bishop, Department of Physiology, The University of Texas Health Science Center, San Antonio, Texas 78284-7756, USA P. A.
Author :Michael W.B. Bradbury Publisher :Springer Science & Business Media ISBN 13 :3642768946 Total Pages :562 pages Book Rating :4.6/5 (427 download)
Book Synopsis Physiology and Pharmacology of the Blood-Brain Barrier by : Michael W.B. Bradbury
Download or read book Physiology and Pharmacology of the Blood-Brain Barrier written by Michael W.B. Bradbury and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 562 pages. Available in PDF, EPUB and Kindle. Book excerpt: The blood-brain barrier is still not completely understood and therefore the subject of fascinating study. How are endogenous substances transported through the blood-brain barrier? What are the known therapeutic and toxic agents? How are they transported across cerebral microvessels? The discussion of these and other questions with far-reaching consequences for all neuroscientists can be found in this volume. This authoritative and up-to-date review of the blood-brain barrier gives a proper understanding of the topic. The experimental principles, the results of very recent research, as well as the implications that experimental research has for clinical treatment are thoroughly covered. Information is given on: - new findings based on classical physiological and pharmacological techniques, - results obtained from brain capillaries in vitro and in culture, - results obtained from the new scanning techniques (PET and MRI), - the immunology of the blood-brain barrier, - trace metal transport, - the pathological breakdown of the barrier and - the modification of drugs to increase their entry into the brain. Here is a source of information that is invaluable to specialists concerned with basic research in the neurosciences, with the design of neuropharmacological agents, with the radiological diagnosis of cerebral pathology or with the treatment of cerebral lesions!
Book Synopsis Chemoarchitecture of the Brain by : R. Nieuwenhuys
Download or read book Chemoarchitecture of the Brain written by R. Nieuwenhuys and published by Springer. This book was released on 1985 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Sleep; Physiology, Biochemistry, Psychology, Pharmacology, Clinical Implications by : Werner Paul Koella
Download or read book Sleep; Physiology, Biochemistry, Psychology, Pharmacology, Clinical Implications written by Werner Paul Koella and published by S. Karger AG (Switzerland). This book was released on 1973 with total page 636 pages. Available in PDF, EPUB and Kindle. Book excerpt: