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Physiology And Pharmacology Of Bone
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Book Synopsis Physiology and Pharmacology of Bone by : Gregory R. Mundy
Download or read book Physiology and Pharmacology of Bone written by Gregory R. Mundy and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 774 pages. Available in PDF, EPUB and Kindle. Book excerpt: The authors, all accomplished and world-renowned experts in their topic areas, have provided controversial and up-to-date accounts of the current status of research in calcium and bone metabolism by reviewing major areas of basic science which have an impact on the understanding of bone diseases and related disorders.
Book Synopsis Physiology and Pharmacology of Bone by : Gregory R. Mundy
Download or read book Physiology and Pharmacology of Bone written by Gregory R. Mundy and published by Springer. This book was released on 2011-12-27 with total page 762 pages. Available in PDF, EPUB and Kindle. Book excerpt: The authors, all accomplished and world-renowned experts in their topic areas, have provided controversial and up-to-date accounts of the current status of research in calcium and bone metabolism by reviewing major areas of basic science which have an impact on the understanding of bone diseases and related disorders.
Book Synopsis Bone Regulatory Factors by : Antonio Pecile
Download or read book Bone Regulatory Factors written by Antonio Pecile and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt: Includes all lectures presented at the NATO ASI Course on title] held in Erice, Sicily, May 1989. Covers morphological, chemical, biochemical, physiological and pathophysiological aspects of bone formation and resorption, focusing on regulatory factors and indicating the new directions that are ope
Download or read book Encyclopedia of Bone Biology written by and published by Academic Press. This book was released on 2020-06-26 with total page 2390 pages. Available in PDF, EPUB and Kindle. Book excerpt: Encyclopedia of Bone Biology, Three Volume Set covers hot topics from within the rapidly expanding field of bone biology and skeletal research, enabling a complete understanding of both bone physiology and its relation to other organs and pathophysiology. This encyclopedia will serve as a vital resource for those involved in bone research, research in other fields that cross link with bone, such as metabolism and immunology, and physicians who treat bone diseases. Each article provides a comprehensive overview of the selected topic to inform a broad spectrum of readers from advanced undergraduate students to research professionals. Chapters also explore the latest advances and hot topics that have emerged in recent years, including the Hematopoietic Niche and Nuclear Receptors. In the electronic edition, each chapter will include hyperlinked references and further readings as well as cross-references to related articles. Incorporates perspectives from experts working within the domains of biomedicine, including physiology, pathobiology, pharmacology, immunology, endocrinology, orthopedics and metabolism Provides an authoritative introduction for non-specialists and readers from undergraduate level upwards, as well as up-to-date foundational content for those familiar with the field Includes multimedia features, cross-references and color images/videos
Book Synopsis The Physiology of Bone by : Janet Vaughan
Download or read book The Physiology of Bone written by Janet Vaughan and published by . This book was released on 1970 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Principles of Bone Biology by : John P. Bilezikian
Download or read book Principles of Bone Biology written by John P. Bilezikian and published by Academic Press. This book was released on 2008-09-29 with total page 2074 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Bone Biology provides the most comprehensive, authoritative reference on the study of bone biology and related diseases. It is the essential resource for anyone involved in the study of bone biology. Bone research in recent years has generated enormous attention, mainly because of the broad public health implications of osteoporosis and related bone disorders. - Provides a "one-stop" shop. There is no need to search through many research journals or books to glean the information one wants...it is all in one source written by the experts in the field - The essential resource for anyone involved in the study of bones and bone diseases - Takes the reader from the basic elements of fundamental research to the most sophisticated concepts in therapeutics - Readers can easily search and locate information quickly as it will be online with this new edition
Download or read book The Skeleton written by Edward J. Massaro and published by Springer Science & Business Media. This book was released on 2004-02-16 with total page 812 pages. Available in PDF, EPUB and Kindle. Book excerpt: A cutting-edge review of the biochemical, physiological, pharmacological, genetic, and molecular interactions involved in the development and homeostasis of the skeleton. Topics range from chondrogenesis, chondrocytes, and cartilage to skeletal dysmorphology, and include the control of skeletal development, osteoblastic cell differentiation, and bone induction, growth, remodeling, and mineralization. The authors' understanding of bone physiology-and how it is modified throughout all the stages of life-offers novel approaches for improving the endurance of load-bearing implants, achieving life-long optimal bone strength, overcoming microgravity situations (space flight), and hastening the healing of fractures, osteotomies, and antrodeses.
Book Synopsis Bisphosphonates in Bone Disease by : Herbert Fleisch
Download or read book Bisphosphonates in Bone Disease written by Herbert Fleisch and published by Elsevier. This book was released on 2000-04-18 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is an essential handbook on bisphosphonates, the most widely used new class of drugs for osteoporosis therapy. It reviews basic physiology in addition to the indications and adverse reactions of these drugs. Bisphosphonates in Bone Disease, 4E, discusses the compounds' chemistry, mechanisms of action, and animal toxicology before presenting a clinical picture of the diseases treated by bisphosphonates. The book provides a table listing the trade names of the commercially available bisphosphonates, registered indications, and the available forms for various countries. The revised Fourth Edition contains approximately 50% new material, including information on all of the latest drugs. * The revised fourth edition contains approximately 50% new material * Includes information on all the latest drugs
Download or read book Osteoimmunology written by Joseph Lorenzo and published by Academic Press. This book was released on 2015-09-23 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: Osteoimmunology: Interactions of the Immune and Skeletal Systems, Second Edition, explores the advancements that have been made in the field during the last 40 years, including valuable information on our understanding of the interactions between hematopoietic, immune, and bone cells, now known as the field of osteoimmunology. This comprehensive work offers the most extensive summaries of research trends in the field and their translation into new therapeutics. Early chapters deal with the development of osteoblasts, osteoclasts, hematopoietic stem cells, T and B-lymphocytes, and communications between these cellular elements, while later sections contain discussions of the signaling pathways by which RANKL influences osteoclast development and function. Subsequent chapters explore the effects that estrogen has on bone and the immune system, the development of pathologic conditions, and the growing research around osteoporosis, Paget’s disease, the genetics of bone disease, and bone cancer metastasis. Explains the intricate interaction between the immune system and bone Features detailed discussions of the key cellular and molecular mechanisms governing the homeostasis of the individual systems Facilitates greater understanding of osteoimmunologic networks, their environments, and how this understanding leads to better treatments for human diseases involving both systems
Download or read book Osteoimmunology written by Joseph Lorenzo and published by Academic Press. This book was released on 2010-09-24 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bone and the immune system are both complex tissues, which, respectively, regulate the skeleton and the body's responses to invading pathogens. Critical interactions between these two organ systems frequently occur, particularly in the development of immune cells in the bone marrow and for the function of bone cells in health and disease. This book provides a detailed overview of the many ways that bone and immune cells interact. The goal is to provide basic and clinical scientists with a better understanding of the role that the immune system and bone play in the development and function of each other so that advances in both fields will be facilitated. The focus of the book will be both on basic pathways and translational science, which will apply basic knowledge to clinical diseases. Chapter content will range from basic descriptions of the various cell systems and their development to the signals that cause them to interact during normal physiology and disease. This is a rapidly developing area that is of interest to a wide spectrum of researchers, students, and fellows in immunology, rheumatology, hematology, and bone biology--all of whom need to develop a more complete understanding of their previously separate disciplines and the mechanisms by which they interact. - Presents a comprehensive, translational source for all aspects of osteoimmunology in one reference work - Experts in bone biology and immunology (from all areas of academic and medical research) take readers from the bench research (cellular and molecular mechanism), through genomic and proteomic analysis, all the way to clinical analysis (histopathology and imaging) and new therapeutic approaches - Clear presentations by bone biologists of the cellular and molecular mechanisms underlying bone cell development leading to bone and immunological diseases such as Lupus - Clear presentations by immunologists of how immune cells develop and how the immune system plays a role in bone diseases like osteoporosis and arthritis
Book Synopsis Fundamental and Clinical Bone Physiology by : Marshall R. Urist
Download or read book Fundamental and Clinical Bone Physiology written by Marshall R. Urist and published by Lippincott Williams & Wilkins. This book was released on 1980 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Russo and Tilla's excitement upon arriving in Rome with their baby daughter is soon dulled by their discovery that the grand facades of polished marble mask an underworld of corrupt landlords and vermin-infested tenements. There are also far too may doctors--some skilled, but others positively dangerous. Ruso thinks he has been offered a reputable medical practice only to find that his predecessor, Doctor Kleitos, has fled, leaving a dead man in a barrel on the doorstep and the warning "Be careful who you trust." Distracted by the body and his efforts to help a friend win the hand of a rich young heiress, Ruso makes a grave mistake, causing him to question his own competence and integrity. With Ruso's reputation under threat, he and Tilla must protect their small family from Doctor Kleito's debt collectors and find allies in their new home while they track down the vanished doctor and find out the truth about the father of the heiress--Russo's patient--and the unfortunate man in the barrel."--
Download or read book Bone Toxicology written by Susan Y. Smith and published by Springer. This book was released on 2017-09-27 with total page 479 pages. Available in PDF, EPUB and Kindle. Book excerpt: The content of this book is intended to provide the toxicologist in drug development in the pharmaceutical and biotechnology industries with a broad understanding of bone and its interactions with other organ systems in safety assessments. The book is divided into three parts. The first part describes our current understanding of bone biology and its primary regulatory pathways. Additional chapters address regulatory and study design considerations for incorporating bone end points in toxicology studies, with special consideration being given to juvenile toxicology studies. This is intended to address recent regulatory requirements to evaluate skeletal development for drugs in development for pediatric populations. The second part of the book describes the principal techniques and methods used in bone research; understanding how these end-points are derived is fundamental to their appropriate application. These first two parts of the book provide the background and the means to develop the concepts in part three which describes bone and its interaction with other organ systems. The unique series of chapters in part three, contributed to by key leaders in their respective fields and in bone research, provides a comprehensive collective work. Although constantly evolving, the crosstalk and interaction of the skeleton with several organ systems is now recognized and well documented, such as for the reproductive system, muscle and kidney, while our understanding of the interaction with other organ systems, such as the immune system and CNS, is in its infancy. Recent work highlights the key role of the skeleton in the regulation of energy metabolism and the impact this has on research in metabolic diseases such as obesity and diabetes. The hope is that this book will enlighten many and encourage more to explore the impact of new compounds on the skeleton in the development of effective and safe drugs.
Download or read book Osteoimmunology written by Yongwon Choi and published by Springer Science & Business Media. This book was released on 2009-12-01 with total page 135 pages. Available in PDF, EPUB and Kindle. Book excerpt: It has only recently been appreciated that the immune and skeletal systems have major interactions. It is now well documented that osteoclasts, which are important cellular mediators of skeletal homeostasis, are derived from hematopoietic precursors that also give rise to immune cells. In addition, numerous cytokines that were first shown to regulate immune cell function have also been demonstrated to regulate bone cells and influence skeletal health. Conversely, products of bone cells appear critical for the engraftment of marrow in bone, the normal development of the hematopoietic and immune systems and provide niche for long-term memory B and T cells. In the past scientists involved in immune and bone cell investigations have rarely interacted in a significant way as these disciplines have developed independently and, for the most part, remain separate. The conference will bring together leading international scientists from both fields to interact so that new collaboration can develop and more rapid progress in understanding the relationships between these fields can be achieved. Short talks will be selected from abstracts from the international community. This conference will have a format to provide an environment of maximum interaction and interchange through lectures, posters, and open discussion.
Book Synopsis Physiology And Pathology by : Geoffrey Bourne
Download or read book Physiology And Pathology written by Geoffrey Bourne and published by Elsevier. This book was released on 2012-12-02 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Biochemistry and Physiology of Bone, Second Edition: Volume II: Physiology and Pathology investigates the physiological and pathological aspects of bone, including the blood vessels that nourish the bones; the mechanisms of bone formation, growth, repair, and transplantation; and the role of hormones and vitamins in the formation and maintenance of bone. It explores the circulation of bone, the pathological calcification and radiation effects on bone, the metabolism of growth hormones and skeletal tissue, enamel and dentin matrix glycoproteins, and the role of calcitonin in homeostasis. Organized into nine chapters, this edition begins with an overview of the circulation of bone, including the overall blood supply of a long bone. It discusses the phosphatase and its histological distribution in mature and developing bone, the presence of glycoproteins in the organic matrix of enamel and dentin, and human dwarfism and human growth hormone replacement therapy. It explains the roles of vitamins and the effects of calcitonin and vitamin deficiency on bone growth and development. The book concludes with a chapter on the chemistry of calcification and some types of abnormal calcification. This book is a valuable resource for biochemists, cell biologists, physiologists, anatomists, orthopedists, pathologists, clinicians, biomedical engineers, graduate students, professors, and others interested in the physiology and pathology of bone.
Book Synopsis The Physiology of Bone by : Janet Maria Vaughan
Download or read book The Physiology of Bone written by Janet Maria Vaughan and published by . This book was released on 1975 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Biochemistry and Physiology of Bone by : Geoffrey Howard Bourne
Download or read book The Biochemistry and Physiology of Bone written by Geoffrey Howard Bourne and published by . This book was released on 1971 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Osteoimmunology written by Yongwon Choi and published by Springer Science & Business Media. This book was released on 2007-10-05 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Key Regulator of Postnatal Skeletal Remodeling.- Ectodomain Shedding of Receptor Activator of NF-KB Ligand.- The Negative Role Of Ids In Osteoclastogenesis.- Functional Genetic and Genomic Analysis of Modeled Arthritis.- Dexamethsone Suppresses Bone Formation via the Osteoclast.- Immunologic Regulation Of Bone Development.- Pth Regulates The Hematopoietic Stem Cell Niche In Bone.- Regulation Of Hematopoietic Stem Cells In The Osteoblastic Niche.- The Chemokine Cxcl12 And Regulation Of Hsc And Lymphocyte Development In The Bone Marrow Niche.- Osteoclast Precursor Cells.- Interaction with estrogen receptors as treatment of arthritis and osteoporosis.- Novel Signaling Pathways And Therapeutic Targets In Osteoclasts.- The Enigmatic Function of TREM-2 in Osteoclastogenesis.- Role of cell-matrix interactions in osteoclast differentiation.- Positive and negative roles of IL-6, STAT3 and SOCS3 in inflammatory arthritis.- Control of Osteoclast activity and bone loss by IKK subunits: new targets for therapy.- Targeting Osteoporosis And Rheumatoid Arthritis By Active Vaccination Against Rankl.- RANKL Inhibition: From Mice to Men (and Women).
