Physico Chemical Control Of Cell Function

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Physico-Chemical Control of Cell Function

Author : Cesare Gargioli
Publisher : Frontiers Media SA
ISBN 13 : 2889459985
Total Pages : 272 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis Physico-Chemical Control of Cell Function by : Cesare Gargioli

Download or read book Physico-Chemical Control of Cell Function written by Cesare Gargioli and published by Frontiers Media SA. This book was released on 2019-10-17 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extracellular Matrix (ECM) has been considered for a long time merely a scaffold sustaining cell and tissue function. Despite this simplistic view shared by many, nowadays ECM and their mechanic-physical and chemical characteristic acquired a progressive larger role actively regulating cell life: survival, proliferation, gene expression and differentiation. The interplay between cells and the ECM is continuously controlled at the cell level in a dynamic way. While cells synthesize the raw components of the ECM, this in turn impacts on cell function by providing chemical, topographical and mechanical hints. Such stimuli have been proven to control several aspects of cell function, including survival, proliferation, differentiation and migration. The molecular pathways activated by cells in response to the physical cues arising from the ECM are being disclosed and thus the possibility to control cell function through materials design is becoming more realistic. Current in vitro protocols, relying in 2D cell culture system, entail reductionist approaches to the complexity of cell-ECM interaction and result in cells rapidly losing their distinctive functions in culture. Understanding and replicating the 3D microenvironmental cues affecting cell function appears as a mandatory requirement for the development of next-generation biomaterials, as well as for the establishment of more physiologically relevant and predictive in vitro models of diseases. Such an effort will require a multidisciplinary approach at the convergence of biophysics, biology, nanotechnology, and bioengineering.

Molecular Biology of the Cell

Author :
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

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Book Synopsis Molecular Biology of the Cell by :

Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Biopsychosocial Model of Health and Disease

Author : Derek Bolton
Publisher : Springer
ISBN 13 : 3030118991
Total Pages : 149 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis The Biopsychosocial Model of Health and Disease by : Derek Bolton

Download or read book The Biopsychosocial Model of Health and Disease written by Derek Bolton and published by Springer. This book was released on 2019-03-28 with total page 149 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book is a systematic update of the philosophical and scientific foundations of the biopsychosocial model of health, disease and healthcare. First proposed by George Engel 40 years ago, the Biopsychosocial Model is much cited in healthcare settings worldwide, but has been increasingly criticised for being vague, lacking in content, and in need of reworking in the light of recent developments. The book confronts the rapid changes to psychological science, neuroscience, healthcare, and philosophy that have occurred since the model was first proposed and addresses key issues such as the model’s scientific basis, clinical utility, and philosophical coherence. The authors conceptualise biology and the psychosocial as in the same ontological space, interlinked by systems of communication-based regulatory control which constitute a new kind of causation. These are distinguished from physical and chemical laws, most clearly because they can break down, thus providing the basis for difference between health and disease. This work offers an urgent update to the model’s scientific and philosophical foundations, providing a new and coherent account of causal interactions between the biological, the psychological and social.

Cell Colonization Control by Physical and Chemical Modification of Materials

Author : L. Baèáková
Publisher :
ISBN 13 : 9781604568875
Total Pages : 0 pages
Book Rating : 4.5/5 (688 download)

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Book Synopsis Cell Colonization Control by Physical and Chemical Modification of Materials by : L. Baèáková

Download or read book Cell Colonization Control by Physical and Chemical Modification of Materials written by L. Baèáková and published by . This book was released on 2009 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cell-material interface plays a key role in the interaction of cells with artificial materials designed for construction of body implants or tissue engineering. Physical and chemical properties of the material surface, such as its polarity, wettability, electrical charge and conductivity, roughness and morphology, rigidity or elasticity as well as the presence of various chemical functional groups, strongly influence the cell adhesion. The latter is mediated by adsorption of cell adhesion-mediating molecules (eg: vitronectin, fibronectin, collagen, laminin, fibrinogen) from the serum of the culture medium or body fluids in appropriate spatial conformation or flexibility enabling the accessibility of specific sites on these molecules (eg: certain amino acid sequences or saccharide-based ligands) by adhesion receptors on the cell membrane (eg: integrins). After binding these ligands, the adhesion receptors are recruited into focal adhesion plaques, where they associate with cascades of various structural and signalling molecules, such as cytoskeletal proteins and kinases. By these cascades, the signal provided by the cell-material interaction is delivered to the cell nucleus. It influences the gene expression, and thus the further behavior of cells, manifested by their viability, synthesis of various molecules, proliferation, differentiation, functioning, immune activation, stress adaptation or cell death. This interdisciplinary review involves: (i) physical modifications of the material surface by plasma discharge, irradiation with ions or ultraviolet light and effects of these modifications on the surface wettability, electrical conductivity and formation of chemical functional groups influencing cell adhesion, (ii) deposition of organic or inorganic layers on the material surfaces, especially those nanostructured (eg: nanofibers of fibrin and extracellular matrix molecules, carbon nanoparticles, such as nanodiamonds, fullerenes and nanotubes, nanocomposite metal/C:H layers), (iii) functionalisation of the material surface with amino acids and oligopeptidic ligands for cell adhesion receptors (e.g., GRGDSG), (iv) effect of all these modifications on the extent and strength of adhesion of vascular and bone-derived cells, cell proliferation activity, switch between cell proliferation and differentiation, expression of cell-type specific markers of differentiation and other cell functions.

Magnetic Resonance in Biological Systems

Author : A. Ehrenberg
Publisher : Elsevier
ISBN 13 : 148322676X
Total Pages : 441 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Magnetic Resonance in Biological Systems by : A. Ehrenberg

Download or read book Magnetic Resonance in Biological Systems written by A. Ehrenberg and published by Elsevier. This book was released on 2013-09-24 with total page 441 pages. Available in PDF, EPUB and Kindle. Book excerpt: Magnetic Resonance in Biological Systems, Volume 9 is a collection of manuscripts presented at the Second International Conference on Magnetic Resonance in Biological Systems, held in Wenner-Gren Center, Stockholm, Sweden on June 1966. The conference is sponsored by International Union of Biochemistry Swedish Medical Research Council Swedish Natural Science Research Council Wenner-Gren Center Foundation for Scientific Research. This book contains 51 chapters, and begins with reviews of NMR investigations of biological macromolecules, including proteins, amino acids, and glycylglycine copper (II). Considerable chapters are devoted to numerous biological studies using the electronic paramagnetic resonance (EPR), thus introducing the branch of science called submolecular biology. This book also explores other applications of NMR and EPR, with special emphasis on blood component analysis and protein-metal complexes. The final chapters survey the principles and applications of Mössbauer spectroscopy. This book will prove useful to analytical chemists and biologists.

Anatomy and Physiology

Author : J. Gordon Betts
Publisher :
ISBN 13 : 9781947172807
Total Pages : 0 pages
Book Rating : 4.1/5 (728 download)

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Book Synopsis Anatomy and Physiology by : J. Gordon Betts

Download or read book Anatomy and Physiology written by J. Gordon Betts and published by . This book was released on 2013-04-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Carotenoids

Author : John T. Landrum
Publisher : CRC Press
ISBN 13 : 1420052314
Total Pages : 562 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Carotenoids by : John T. Landrum

Download or read book Carotenoids written by John T. Landrum and published by CRC Press. This book was released on 2009-12-21 with total page 562 pages. Available in PDF, EPUB and Kindle. Book excerpt: Carotenoids are of great interest due to their essential biological functions in both plants and animals. However, the properties and functions of carotenoids in natural systems are surprisingly complex. With an emphasis on the chemical aspects of these compounds, Carotenoids: Physical, Chemical, and Biological Functions and Properties presents a b

The Cell: A Very Short Introduction

Author : Terence Allen
Publisher : Oxford University Press
ISBN 13 : 0199578753
Total Pages : 161 pages
Book Rating : 4.1/5 (995 download)

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Book Synopsis The Cell: A Very Short Introduction by : Terence Allen

Download or read book The Cell: A Very Short Introduction written by Terence Allen and published by Oxford University Press. This book was released on 2011-09-29 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduces cells, discussing their structure, life cycle, and what they can do.

Janeway's Immunobiology

Author : Kenneth Murphy
Publisher : Garland Science
ISBN 13 : 9780815344575
Total Pages : pages
Book Rating : 4.3/5 (445 download)

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Book Synopsis Janeway's Immunobiology by : Kenneth Murphy

Download or read book Janeway's Immunobiology written by Kenneth Murphy and published by Garland Science. This book was released on 2010-06-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.

Biology for AP ® Courses

Author : Julianne Zedalis
Publisher :
ISBN 13 : 9781947172401
Total Pages : 1923 pages
Book Rating : 4.1/5 (724 download)

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Book Synopsis Biology for AP ® Courses by : Julianne Zedalis

Download or read book Biology for AP ® Courses written by Julianne Zedalis and published by . This book was released on 2017-10-16 with total page 1923 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biology for AP® courses covers the scope and sequence requirements of a typical two-semester Advanced Placement® biology course. The text provides comprehensive coverage of foundational research and core biology concepts through an evolutionary lens. Biology for AP® Courses was designed to meet and exceed the requirements of the College Board’s AP® Biology framework while allowing significant flexibility for instructors. Each section of the book includes an introduction based on the AP® curriculum and includes rich features that engage students in scientific practice and AP® test preparation; it also highlights careers and research opportunities in biological sciences.

Biomedical Mass Transport and Chemical Reaction

Author : James S. Ultman
Publisher : John Wiley & Sons
ISBN 13 : 0471656321
Total Pages : 654 pages
Book Rating : 4.4/5 (716 download)

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Book Synopsis Biomedical Mass Transport and Chemical Reaction by : James S. Ultman

Download or read book Biomedical Mass Transport and Chemical Reaction written by James S. Ultman and published by John Wiley & Sons. This book was released on 2016-06-13 with total page 654 pages. Available in PDF, EPUB and Kindle. Book excerpt: Teaches the fundamentals of mass transport with a unique approach emphasizing engineering principles in a biomedical environment Includes a basic review of physiology, chemical thermodynamics, chemical kinetics, mass transport, fluid mechanics and relevant mathematical methods Teaches engineering principles and mathematical modelling useful in the broad range of problems that students will encounter in their academic programs as well as later on in their careers Illustrates principles with examples taken from physiology and medicine or with design problems involving biomedical devices Stresses the simplification of problem formulations based on key geometric and functional features that permit practical analyses of biomedical applications Offers a web site of homework problems associated with each chapter and solutions available to instructors Homework problems related to each chapter are available from a supplementary website (

Cell Biology by the Numbers

Author : Ron Milo
Publisher : Garland Science
ISBN 13 : 1317230698
Total Pages : 400 pages
Book Rating : 4.3/5 (172 download)

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Book Synopsis Cell Biology by the Numbers by : Ron Milo

Download or read book Cell Biology by the Numbers written by Ron Milo and published by Garland Science. This book was released on 2015-12-07 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Top 25 CHOICE 2016 Title, and recipient of the CHOICE Outstanding Academic Title (OAT) Award. How much energy is released in ATP hydrolysis? How many mRNAs are in a cell? How genetically similar are two random people? What is faster, transcription or translation?Cell Biology by the Numbers explores these questions and dozens of others provid

Microbiology

Author : Nina T. Parker
Publisher :
ISBN 13 : 9781947172791
Total Pages : 0 pages
Book Rating : 4.1/5 (727 download)

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Book Synopsis Microbiology by : Nina T. Parker

Download or read book Microbiology written by Nina T. Parker and published by . This book was released on 2016-11 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbiology covers the scope and sequence requirements for a single-semester microbiology course for non-majors. The book presents the core concepts of microbiology with a focus on applications for careers in allied health. The pedagogical features of the text make the material interesting and accessible while maintaining the career-application focus and scientific rigor inherent in the subject matter. Microbiology's art program enhances students' understanding of concepts through clear and effective illustrations, diagrams, and photographs.

The Biophysics of Cell Membranes

Author : Richard M. Epand
Publisher : Springer
ISBN 13 : 9811062447
Total Pages : 224 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis The Biophysics of Cell Membranes by : Richard M. Epand

Download or read book The Biophysics of Cell Membranes written by Richard M. Epand and published by Springer. This book was released on 2017-09-25 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume focuses on the modulation of biological membranes by specific biophysical properties. The readers are introduced to emerging biophysical approaches that mimick specific states (like membrane lipid asymmetry, membrane curvature, lipid flip-flop, lipid phase separation) that are relevant to the functioning of biological membranes. The first chapter describes innovative methods to mimic the prevailing asymmetry in biological membranes by forming asymmetrical membranes made of monolayers with different compositions. One of the chapters illustrates how physical parameters, like curvature and elasticity, can affect and modulate the interactions between lipids and proteins. This volume also describes the sensitivity of certain ion channels to mechanical forces and it presents an analysis of how cell shape is determined by both the cytoskeleton and the lipid domains in the membrane. The last chapter provides evidence that liposomes can be used as a minimal cellular model to reconstitute processes related to the origin of life. Each topic covered in this volume is presented by leading experts in the field who are able to present clear, authoritative and up-to-date reviews. The novelty of the methods proposed and their potential for a deeper molecular description of membrane functioning are particularly relevant experts in the areas of biochemistry, biophysics and cell biology, while also presenting clear and thorough introductions, making the material suitable for students in these fields as well.

Cell Physiology Source Book

Author : Nicholas Sperelakis
Publisher : Elsevier
ISBN 13 : 0080574556
Total Pages : 1262 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Cell Physiology Source Book by : Nicholas Sperelakis

Download or read book Cell Physiology Source Book written by Nicholas Sperelakis and published by Elsevier. This book was released on 2012-12-02 with total page 1262 pages. Available in PDF, EPUB and Kindle. Book excerpt: This authoritative book gathers together a broad range of ideas and topics that define the field. It provides clear, concise, and comprehensive coverage of all aspects of cellular physiology from fundamental concepts to more advanced topics. The Third Edition contains substantial new material. Most chapters have been thoroughly reworked. The book includes chapters on important topics such as sensory transduction, the physiology of protozoa and bacteria, the regulation of cell division, and programmed cell death. - Completely revised and updated - includes 8 new chapters on such topics as membrane structure, intracellular chloride regulation, transport, sensory receptors, pressure, and olfactory/taste receptors - Includes broad coverage of both animal and plant cells - Appendixes review basics of the propagation of action potentials, electricity, and cable properties - Authored by leading experts in the field - Clear, concise, comprehensive coverage of all aspects of cellular physiology from fundamental concepts to more advanced topics

Physicochemical Treatment Processes

Author : Lawrence K. Wang
Publisher : Springer Science & Business Media
ISBN 13 : 1588291650
Total Pages : 731 pages
Book Rating : 4.5/5 (882 download)

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Book Synopsis Physicochemical Treatment Processes by : Lawrence K. Wang

Download or read book Physicochemical Treatment Processes written by Lawrence K. Wang and published by Springer Science & Business Media. This book was released on 2005-03-11 with total page 731 pages. Available in PDF, EPUB and Kindle. Book excerpt: The past 30 years have seen the emergence of a growing desire worldwide to take positive actions to restore and protect the environment from the degrading effects of all forms of pollution: air, noise, solid waste, and water. Because pollution is a direct or indirect consequence of waste, the seemingly idealistic demand for “zero discharge” can be construed as an unrealistic demand for zero waste. However, as long as waste exists, we can only attempt to abate the subsequent pollution by converting it to a less noxious form. Three major questions usually arise when a particular type of pollution has been identified: (1) How serious is the pollution? (2) Is the technology to abate it available? and (3) Do the costs of abatement justify the degree of abatement achieved? The principal intention of the Handbook of Environmental Engineering series is to help readers formulate answers to the last two questions. The traditional approach of applying tried-and-true solutions to specific pollution pr- lems has been a major contributing factor to the success of environmental engineering, and has accounted in large measure for the establishment of a “methodology of pollution c- trol. ” However, realization of the ever-increasing complexity and interrelated nature of current environmental problems makes it imperative that intelligent planning of pollution abatement systems be undertaken.

Plant Chemical Biology

Author : Dominique Audenaert
Publisher : John Wiley & Sons
ISBN 13 : 1118742745
Total Pages : 384 pages
Book Rating : 4.1/5 (187 download)

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Book Synopsis Plant Chemical Biology by : Dominique Audenaert

Download or read book Plant Chemical Biology written by Dominique Audenaert and published by John Wiley & Sons. This book was released on 2013-11-05 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Demonstrates how advances in plant chemical biology can translate to field applications With contributions from a team of leading researchers and pioneers in the field, this book explains how chemical biology is used as a tool to enhance our understanding of plant biology. Readers are introduced to a variety of chemical biology studies that have provided novel insights into plant physiology and plant cellular processes. Moreover, they will discover that chemical biology not only leads to a better understanding of the underlying mechanisms of plant biology, but also the development of practical applications. For example, the authors discuss small molecules that can be used to identify targets of herbicides and develop new herbicides and plant growth regulators. The book begins with a historical perspective on plant chemical biology. Next, the authors introduce the chemical biology toolbox needed to perform successful studies, with chapters covering: Sources of small molecules Identification of new chemical tools by high-throughput screening (HTS) Use of chemical biology to study plant physiology Use of chemical biology to study plant cellular processes Target identification Translation of plant chemical biology from the lab to the field Based on the latest findings and extensively referenced, the book explores available compound collections, principles of assay design, and the use of new research tools for the development of new applications. Plant Chemical Biology is recommended for students and professionals in all facets of plant biology, including molecular biology, physiology, biochemistry, agriculture, horticulture, and agronomy. All readers will discover new approaches that can lead to the development of a healthier and more plentiful global food supply.