Physical Principles and Techniques of Protein Chemistry Part A

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Author :
Publisher : Elsevier
ISBN 13 : 0323141129
Total Pages : 545 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis Physical Principles and Techniques of Protein Chemistry Part A by : Sydney Leach

Download or read book Physical Principles and Techniques of Protein Chemistry Part A written by Sydney Leach and published by Elsevier. This book was released on 2012-12-02 with total page 545 pages. Available in PDF, EPUB and Kindle. Book excerpt: Physical Principles and Techniques of Protein Chemistry, Part A deals with the principles and application of selected physical methods in protein chemistry evaluation. This book is organized into nine chapters that cover microscopic, crystallographic, and electrophoretic techniques for protein conformational perturbations evaluation. This text first presents a general account of electron microscopy, its specimen preparation, optimum conditions for high resolution, measurement of electron micrographs, and illustrative examples of protein study. This book then examines the different types of maps from X-ray methods and the diffraction data from fibrous proteins. The subsequent chapters cover discussions on UV spectroscopy of proteins; luminescence properties of proteins and related compounds; and perturbation and flow methods for evaluation of proteins' dynamic properties and rate constants. Other chapters deal with the evaluation of proteins' dielectric properties using dielectric relaxation, electric birefringence, and dichroism techniques. The concluding chapters outline the theoretical and experimental advances of the electrophoretic and gel filtration methods for the study of protein structure and molecular weight. This book is of great value to chemists, biologists, and researchers who have great appreciation of protein chemistry.

Physical Principles and Techniques of Protein Chemistry Part B

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Publisher : Elsevier
ISBN 13 : 0323141137
Total Pages : 508 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis Physical Principles and Techniques of Protein Chemistry Part B by : Sydney Leach

Download or read book Physical Principles and Techniques of Protein Chemistry Part B written by Sydney Leach and published by Elsevier. This book was released on 2012-12-02 with total page 508 pages. Available in PDF, EPUB and Kindle. Book excerpt: Physical Principles and Techniques of Protein Chemistry, Part B deals with the theories and application of selected physical methods in protein chemistry evaluation. This book is divided into seven chapters that cover the ultracentrifugal analysis, light scattering, infrared (IR) methods, nuclear magnetic resonance (NMR) spectroscopy, and differential thermal analysis of protein properties. This text first describes the fundamental ideas and methodology of sedimentation analysis of ideal noninteracting solutes and the problems of nonideality and solute-solute interaction. This book then deals with the problems involved in the interpretation of viscometric data for evaluation of intrinsic viscosity of proteins. The following chapters examine the principles, measurement and analysis of spectra, and experimental techniques of light scattering, IR, and NMR spectroscopic methods. Discussions on coordination phenomena, identification of binding sites, and ion binding in the crystalline state and in protein solutions are included. The concluding chapter presents some examples of protein analysis using differential thermal analysis technique. This book is of great value to chemists, biologists, and researchers who have great appreciation of protein chemistry.

Physical Principles and Techniques of Protein Chemistry Part C

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Publisher : Elsevier
ISBN 13 : 0323141145
Total Pages : 639 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis Physical Principles and Techniques of Protein Chemistry Part C by : Sydney Leach

Download or read book Physical Principles and Techniques of Protein Chemistry Part C written by Sydney Leach and published by Elsevier. This book was released on 2012-12-02 with total page 639 pages. Available in PDF, EPUB and Kindle. Book excerpt: Physical Principles and Techniques of Protein Chemistry, Part C focuses on the effects of intermolecular interactions that are transmitted between ligands and proteins and from protein to protein. This book discusses the density and volume change measurements; direct volume change; osmotic pressure; and small-angle X-ray scattering. The theory of particulate scattering; pulsed nuclear magnetic resonance; absorption of water by diamagnetic molecules; and use of least squares in data analysis are also elaborated. This text likewise covers the iteration process; optical rotatory dispersion and the main chain conformation of proteins; and basic relations for optically active molecules. Other topics include the circular dichroism, secondary structure of proteins, visible rotatory dispersion, and peptide cotton effects. This publication is intended for protein chemists, but is also useful to biologists, medical practitioners, and students researching on protein chemistry.

Physical Principles and Techniques of Protein Chemistry

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Publisher :
ISBN 13 :
Total Pages : 546 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Physical Principles and Techniques of Protein Chemistry by : Sydney J. Leach

Download or read book Physical Principles and Techniques of Protein Chemistry written by Sydney J. Leach and published by . This book was released on 1969 with total page 546 pages. Available in PDF, EPUB and Kindle. Book excerpt: Physical Principles and Techniques of Protein Chemistry, Part A deals with the principles and application of selected physical methods in protein chemistry evaluation. This book is organized into nine chapters that cover microscopic, crystallographic, and electrophoretic techniques for protein conformational perturbations evaluation. This text first presents a general account of electron microscopy, its specimen preparation, optimum conditions for high resolution, measurement of electron micrographs, and illustrative examples of protein study. This book then examines the different types of map ...

Characterization of Proteins

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Publisher : Springer
ISBN 13 : 1592594379
Total Pages : 570 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Characterization of Proteins by : Felix Franks

Download or read book Characterization of Proteins written by Felix Franks and published by Springer. This book was released on 2007-10-03 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proteins are the servants of life. They occur in all component parts of living organisms and are staggering in their functional var- ty, despite their chemical similarity. Even the simplest single-cell organism contains a thousand different proteins, fulfilling a wide range of life-supporting roles. Their production is controlled by the cell’s genetic machinery, and a malfunction of even one protein in the cell will give rise to pathological symptoms. Additions to the total number of known proteins are constantly being made on an increasing scale through the discovery of mutant strains or their production by genetic manipulation; this latter technology has become known as protein engineering. The in vivo functioning of proteins depends critically on the chemical structure of individual peptide chains, but also on the detailed folding of the chains themselves and on their assembly into larger supramolecular structures. The molecules and their fu- tional assemblies possess a limited in vitro stability. Special methods are required for their intact isolation from the source material and for their analysis, both qualitatively and quantitatively. Proteins are also increasingly used as “industrial components,” e.g., in biosensors and immobilized enzymes, because of their specificity, selectivity, and sensitivity. This requires novel and refined proce- ing methods by which the protein isolate can be converted into a form in which it can be utilized.

Methods of Biochemical Analysis

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 0470110813
Total Pages : 395 pages
Book Rating : 4.4/5 (71 download)

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Book Synopsis Methods of Biochemical Analysis by : David Glick

Download or read book Methods of Biochemical Analysis written by David Glick and published by John Wiley & Sons. This book was released on 2009-09-25 with total page 395 pages. Available in PDF, EPUB and Kindle. Book excerpt: An encyclopedia of methods in biochemical analysis, this modern series keeps biochemists and analytical chemists abreast of experimental innovations and improvements in biochemical techniques and instrumentation.

Chemistry of Natural Protein Fibers

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Publisher : Springer Science & Business Media
ISBN 13 : 1461341094
Total Pages : 431 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Chemistry of Natural Protein Fibers by : R. S. Asquith

Download or read book Chemistry of Natural Protein Fibers written by R. S. Asquith and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 431 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume arose originally from the complaints of the editor's students, both undergraduate and postgraduate, that there was no modern book on protein fibers which told enough about protein science and chemical tech nologies related to fibers. By and large this is probably a reasonable cri de coeur. The undergraduate on a technological course, lacking information on the basic scientific techniques used to carry out the research on which his fiber technology is based, can find it difficult to obtain this information. The pure science undergraduate often lacks knowledge of the application of these techniques in protein fiber technology. The young graduates, com mencing research related to some aspect of protein fibers, are drawn from a wide range of scientific disciplines, having been trained as biochemists, chemists, physicists, technologists, and histologists, to name but a few. Generally these new research workers pass through a preliminary "lost" period in which they have to evaluate their background in relation to the wide and differing fields of research in protein fiber science to which they are now exposed. As time goes on they then either develop a wide knowledge covering science and technology or remain in a specific part of their original discipline, with a narrow knowledge of its application in the field of the research degree they are taking.

Spectroscopy In Biochemistry

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Publisher : CRC Press
ISBN 13 : 135109372X
Total Pages : 377 pages
Book Rating : 4.3/5 (51 download)

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Book Synopsis Spectroscopy In Biochemistry by : J.Ellis Bell

Download or read book Spectroscopy In Biochemistry written by J.Ellis Bell and published by CRC Press. This book was released on 2018-05-04 with total page 377 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book has been written in part with the aim of providing a text which will be useful in teaching the biochemical applications of spectroscopy. This book will be of particular use to the biochemist or biologist who does not have a background in spectroscopy, but desires to find out what sort of information spectroscopy can provide. Attention was limited to those techniques most frequently used, and which at present have the widest applications.

The Proteins Pt 5

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Publisher : Elsevier
ISBN 13 : 0323162037
Total Pages : 719 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis The Proteins Pt 5 by : Hans Neurath

Download or read book The Proteins Pt 5 written by Hans Neurath and published by Elsevier. This book was released on 2012-12-02 with total page 719 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Proteins, Third Edition, Volume V discusses the unifying concepts of protein chemistry. This volume contains three chapters that cover specific protein classes, namely, glycoproteins and cyclopeptides. Chapter 1 deals first with the purification and characterization of the N- and O-linked glycosidic groups of glycoproteins. This chapter then describes the oligosaccharide catabolism and the roles of lysosomal hydrolases, and of functions of glycoproteins as mediated by their oligosaccharide groups. Chapter 2 begins with a detailed review of ultraviolet and visible spectroscopic techniques along with their basic principles, as well as theoretical calculations of peptide spectra. This chapter then considers absorption spectroscopy, optical rotary dispersion, and circular dichroism, followed by a discussion on the use of these methods on the secondary, tertiary, and quaternary structures of proteins in solution. Infrared and Raman spectroscopy and their applications to secondary structure analysis of proteins are also included in this chapter. Chapter 3 provides a critical review of naturally occurring and synthetic cyclopeptides, a unique group of molecules that include diverse biological compounds such as toxins, hormones, regulators of ion transport, and antibiotics. Organic chemists and researchers, teachers and undergraduate students will find this book invaluable.

Amino Acids, Peptides and Proteins

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Publisher : Royal Society of Chemistry
ISBN 13 : 0851860141
Total Pages : 276 pages
Book Rating : 4.8/5 (518 download)

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Book Synopsis Amino Acids, Peptides and Proteins by : G. T. Young

Download or read book Amino Acids, Peptides and Proteins written by G. T. Young and published by Royal Society of Chemistry. This book was released on 1969 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: Specialist Periodical Reports provide systematic and detailed review coverage of progress in the major areas of chemical research. Written by experts in their specialist fields the series creates a unique service for the active research chemist, supplying regular critical in-depth accounts of progress in particular areas of chemistry. For over 80 years the Royal Society of Chemistry and its predecessor, the Chemical Society, have been publishing reports charting developments in chemistry, which originally took the form of Annual Reports. However, by 1967 the whole spectrum of chemistry could no longer be contained within one volume and the series Specialist Periodical Reports was born. The Annual Reports themselves still existed but were divided into two, and subsequently three, volumes covering Inorganic, Organic and Physical Chemistry. For more general coverage of the highlights in chemistry they remain a 'must'. Since that time the SPR series has altered according to the fluctuating degree of activity in various fields of chemistry. Some titles have remained unchanged, while others have altered their emphasis along with their titles; some have been combined under a new name whereas others have had to be discontinued. The current list of Specialist Periodical Reports can be seen on the inside flap of this volume.

Biosimilars and Interchangeable Biologics

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Publisher : CRC Press
ISBN 13 : 149874348X
Total Pages : 599 pages
Book Rating : 4.4/5 (987 download)

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Book Synopsis Biosimilars and Interchangeable Biologics by : Sarfaraz K. Niazi

Download or read book Biosimilars and Interchangeable Biologics written by Sarfaraz K. Niazi and published by CRC Press. This book was released on 2018-10-30 with total page 599 pages. Available in PDF, EPUB and Kindle. Book excerpt: What’s the Deal with Biosimilars? Biosimilars are gaining momentum as new protein therapeutic candidates that can help fill a vital need in the healthcare industry. The biological drugs are produced by recombinant DNA technology that allows for large-scale production and an overall reduction time in costs and development. Part of a two-volume set that covers varying aspects of biosimilars, Biosimilars and Interchangeable Biologics: Strategic Elements explores the strategic planning side of biosimilar drugs and targets issues surrounding biosimilars that are linked to legal matters. This includes principal patents and intellectual property, regulatory pathways, and concerns about affordability on a global scale. It addresses the complexity of biosimilar products, and it discusses the utilization of biosimilars and related biological drugs in expanding world markets. Of specific interest to practitioners, researchers, and scientists in the biopharmaceutical industry, this volume examines the science, technology, finance, legality, ethics, and politics of biosimilar drugs. It considers strategic planning elements that include an overall understanding of the history and the current status of the art and science of biosimilars, and it provides detailed descriptions of the legal, regulatory, and commercial characteristics. The book also presents a global strategy on how to build, take to market, and manage the next generation of biosimilars throughout their life cycle.

Structure in Protein Chemistry

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Publisher : Garland Science
ISBN 13 : 1136843507
Total Pages : 1576 pages
Book Rating : 4.1/5 (368 download)

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Book Synopsis Structure in Protein Chemistry by : Jack Kyte

Download or read book Structure in Protein Chemistry written by Jack Kyte and published by Garland Science. This book was released on 2006-11-01 with total page 1576 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of Structure in Protein Chemistry showcases the latest developments and innovations in the field of protein structure analysis and prediction. The book begins by explaining how proteins are purified and describes methods for elucidating their sequences of amino acids and defining their posttranslational modifications. Comprehensive explanations of crystallography and of noncovalent forces-ionic interactions, hydrogen bonding, and the hydrophobic effect-act as a prelude to an exhaustive description of the atomic details of the structures of proteins. The resulting understanding of protein molecular structure forms the basis for discussions of the evolution of proteins, the symmetry of the oligomeric associations that produce them, and the chemical, mathematical, and physical basis of the techniques used to study their structures. The latter include image reconstruction, nuclear magnetic resonance spectroscopy, proton exchange, optical spectroscopy, electrophoresis, covalent cross-linking, chemical modification, immunochemistry, hydrodynamics, and the scattering of light, X-radiation, and neutrons. These procedures are applied to study the folding of polypeptides and the assembly of oligomers. Biological membranes and their proteins are also discussed. Structure in Protein Chemistry, Second Edition, bridges the gap between introductory biophysical chemistry courses and research literature. It serves as a comprehensive textbook for advanced undergraduates and graduate students in biochemistry, biophysics, and structural and molecular biology. Professionals engaged in chemical, biochemical, and molecular biological research will find it a useful reference.

Biophysical Chemistry

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Publisher : Macmillan
ISBN 13 : 9780716711902
Total Pages : 594 pages
Book Rating : 4.7/5 (119 download)

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Book Synopsis Biophysical Chemistry by : Charles R. Cantor

Download or read book Biophysical Chemistry written by Charles R. Cantor and published by Macmillan. This book was released on 1980-04-15 with total page 594 pages. Available in PDF, EPUB and Kindle. Book excerpt: Three-part series remains the definitive text on the physical properties of biological macromolecules and the physical techniques used to study them. It is appropriate for a broad spectrum of advanced undergraduate and graduate courses and serves as a comprehensive reference for researchers. Part I: The Conformation of Biological Macromolecules 1980, paper, 365 pages, 158 illustrations 0-7167-1188-5 Part II: Techniques for the Study of Biological Structure and Function 1980, paper, 365 pages, 158 illustrations 0-7167-1190-7 Part III: The Behavior of Biological Macromolecules 1980, paper, 597 pages, 243 illustrations 0-7167-1192-3

Biophysics

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Publisher : Springer Science & Business Media
ISBN 13 : 3642688772
Total Pages : 967 pages
Book Rating : 4.6/5 (426 download)

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Book Synopsis Biophysics by : W. Hoppe

Download or read book Biophysics written by W. Hoppe and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 967 pages. Available in PDF, EPUB and Kindle. Book excerpt: What is biophysics? As with all subjects which straddle traditional boundaries between fields, it eludes a precise definition. Furthermore, it is impossible to do biophysics without having a certain foundation of knowledge in biology, physics, physical chemistry, chemistry and biochemistry. One approach to a biophysics textbook would be to refer the student to the literature of these neighboring fields, and to leave the selection of the appropriate supplementary material up to the student. The editors of this volume are of the opinion that it is more useful and less time-consuming to present a selection of the supplementary knowledge, in concentrated form, together with the subject matter specific to biophysics. The reader will thus find in this book introductions to such subjects as the structure and function of the cell, the chemical structure of biogenic macromolecules, and even theoretical chemistry. What, indeed, is biophysics? Must we consider it to include physiology, electromedicine, radiation medicine, etc. ? The field has evolved continuously in recent years. Molecular understanding oflife processes has come more and more to the fore. Just as the field of molecular physics has developed to describe structures and processes in the realm of non-living systems, there has been a corresponding development of molecular biophysics.

Advances in Protein Chemistry

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Author :
Publisher : Academic Press
ISBN 13 : 0080582001
Total Pages : 522 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Advances in Protein Chemistry by :

Download or read book Advances in Protein Chemistry written by and published by Academic Press. This book was released on 1974-02-08 with total page 522 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Protein Chemistry

Chemistry and Biochemistry of the Amino Acids

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Publisher : Springer Science & Business Media
ISBN 13 : 9400948328
Total Pages : 694 pages
Book Rating : 4.4/5 (9 download)

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Book Synopsis Chemistry and Biochemistry of the Amino Acids by : Graham Barrett

Download or read book Chemistry and Biochemistry of the Amino Acids written by Graham Barrett and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 694 pages. Available in PDF, EPUB and Kindle. Book excerpt: Amino acids are featured in course syllabuses and in project and research work over a wide spectrum of subject areas in chemistry and biology. Chemists and biochemists using amino acids have many common needs when they turn to the literature for comprehensive information. Among these common interests, analytical studies, in particular, have undergone rapid development in recent years. All other chemical and biochemical aspects of amino acids - synthesis, properties and reactions, preparation of derivatives for use in peptide synthesis, racemization and other fundamental mechanistic knowledge - have been the subject of vigorous progress. This book offers a thorough treatment of all these developing areas, and is structured in the belief that biochemists, physiologists and others will profit from access to information on topics such as the physical chemistry of amino acid solutions, as well as from thorough coverage of amino acid metabolism, biosynthesis and enzyme inhibition; and that chemists will find relevant material in biological areas as well as in the analysis, synthesis and reactions of amino acids.

Methods in Protein Structure and Stability Analysis

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Publisher : Nova Publishers
ISBN 13 : 9781600214042
Total Pages : 382 pages
Book Rating : 4.2/5 (14 download)

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Book Synopsis Methods in Protein Structure and Stability Analysis by : Vladimir N. Uversky

Download or read book Methods in Protein Structure and Stability Analysis written by Vladimir N. Uversky and published by Nova Publishers. This book was released on 2007 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: