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Author : Renata Fonseca Vianna Lopez
Publisher :
ISBN 13 :
Total Pages : 191 pages
Book Rating : 4.:/5 (821 download)
Download or read book Physical Methods to Increase Topical and Transdermal Drug Delivery written by Renata Fonseca Vianna Lopez and published by . This book was released on 2012 with total page 191 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Heather A. E. Benson
Publisher : John Wiley & Sons
ISBN 13 : 1118140494
Total Pages : 393 pages
Book Rating : 4.1/5 (181 download)
Download or read book Topical and Transdermal Drug Delivery written by Heather A. E. Benson and published by John Wiley & Sons. This book was released on 2012-02-03 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt: Practical drug development approaches presented by leading experts Designed to support the development of new, effective therapeutics, Topical and Transdermal Drug Delivery: Principles and Practice explains the principles underlying the field and then demonstrates how these principles are put into practice in the design and development of new drug products. Drawing together and reviewing the latest research findings, the book focuses on practical, tested, and proven approaches that are backed by industry case studies and the authors' firsthand experience. Moreover, the book emphasizes the mechanistic information that is essential for successful drug product development. Topical and Transdermal Drug Delivery: Principles and Practice is divided into two parts: Part One, Current Science, Skin Permeation, and Enhancement Approaches, offers readers a fundamental understanding of the underlying science in the field. It describes the principles and techniques needed to successfully perform experimental approaches, covering such issues as skin permeation, enhancement, and assessment. Part Two, Topical and Transdermal Product Development, guides readers through the complete product development process from concept to approval, offering practical tips and cautions from experts in the field. This part also discusses regulations that are specific to the development of dermal drug products. The final chapter explores current and future trends, forecasting new development techniques and therapeutics. Throughout the book, the authors clearly set forth the basic science and experimental procedures, making it possible for researchers to design their own experimental approaches and accurately interpret their results. With contributions from experienced drug researchers, this text is highly recommended for all researchers involved in topical and transdermal product development who need to know both the state of the science and the standards of practice.
Author : Nayan A. Gujarathi
Publisher : CRC Press
ISBN 13 : 1000577643
Total Pages : 353 pages
Book Rating : 4.0/5 (5 download)
Download or read book Topical and Transdermal Drug Delivery Systems written by Nayan A. Gujarathi and published by CRC Press. This book was released on 2023-02-06 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: Topical and transdermal drug delivery systems (TDDs) have several advantages over traditional drug delivery methods, as they can be less invasive, more sanitary, more cost-effective, and may result in better patient compliance. TDDs play a significant role in therapeutics with a variety of preparations and approaches designed by expert formulation scientists. This volume integrates a wide variety of case studies, research, and theories to reveal their diversity and capture the novel approaches of transdermal and topical drug delivery employed by developers and content experts in the field. It provides an abundance of important information and state-of-the-art research on topical and transdermal drug delivery systems and addresses the basics of drug delivery systems, strategies to enhance permeation across membranes, and formulation and evaluation of diverse dosage forms. The volume presents an evaluation of the pros and cons of conventional drug delivery systems against TDDs and discusses the nuances of micro- and nano-systems in TDDs. The extraordinary packages of nano systems (vesicular systems, polymeric nanoparticles, nanoemulsion and dendrimers) are broadly discussed, and their applications are reviewed through a transdermal route. The book looks at TDDs and the main nanoparticles used in skin diseases and lesions of the aging, such as psoriasis, vitiligo, cancer, lesions of the aging and others. Chapters also discuss polymeric micelles in topical and transdermal delivery; microneedles; emulsion, nanoemulsion and microemulsion; TDDs in pulmonary drug delivery systems; nanoencapsulated nasal drug delivery systems; skin sensitivity and irritation testing for transposing transdermal drug delivery systems; and regulatory aspects of drug development for dermal products. Topical and Transdermal Drug Delivery Systems: Applications and Prospects will be a valuable resource for pharmaceutical scientists and researchers, industry professionals, and academicians and students of the pharmaceutical and biomedical sciences.
Author : Nina Dragicevic
Publisher : Springer
ISBN 13 : 3662532735
Total Pages : 496 pages
Book Rating : 4.6/5 (625 download)
Download or read book Percutaneous Penetration Enhancers Physical Methods in Penetration Enhancement written by Nina Dragicevic and published by Springer. This book was released on 2017-05-04 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: Percutaneous Penetration Enhancers in a mini-series format comprising five volumes, represents the most comprehensive reference on enhancement methods – both well established and recently introduced – in the field of dermal/transdermal drug delivery. In detail the broad range of both chemical and physical methods used to enhance the skin delivery of drugs is described. All aspects of drug delivery and measurement of penetration are covered, and the latest findings are provided on skin structure and function, mathematics in skin permeation, and modern analytical techniques adapted to assess and measure penetration. In offering a detailed description of the methods currently in use for penetration enhancement, this book will be of value for researchers, pharmaceutical scientists, practitioners, and also students.
Author : Nina Dragicevic
Publisher : Springer
ISBN 13 : 3662532700
Total Pages : 411 pages
Book Rating : 4.6/5 (625 download)
Download or read book Percutaneous Penetration Enhancers Drug Penetration Into/Through the Skin written by Nina Dragicevic and published by Springer. This book was released on 2017-05-04 with total page 411 pages. Available in PDF, EPUB and Kindle. Book excerpt: Percutaneous Penetration Enhancers in a mini-series format comprising five volumes, represents the most comprehensive reference on enhancement methods – both well established and recently introduced – in the field of dermal/transdermal drug delivery. In detail the broad range of both chemical and physical methods used to enhance the skin delivery of drugs is described. All aspects of drug delivery and measurement of penetration are covered, and the latest findings are provided on skin structure and function, mathematics in skin permeation, and modern analytical techniques adapted to assess and measure penetration. In offering a detailed description of the methods currently in use for penetration enhancement, this book will be of value for researchers, pharmaceutical scientists, practitioners, students and dermatological scientists or dermatologists.
Author : Kevin Ita
Publisher : Academic Press
ISBN 13 : 0128225513
Total Pages : 324 pages
Book Rating : 4.1/5 (282 download)
Download or read book Transdermal Drug Delivery written by Kevin Ita and published by Academic Press. This book was released on 2020-06-12 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: Transdermal Drug Delivery: Concepts and Application provides comprehensive background knowledge and documents the most recent advances made in the field of transdermal drug delivery. It provides comprehensive and updated information regarding most technologies and formulation strategies used for transdermal drug delivery. There has been recent growth in the number of research articles, reviews, and other types of publications in the field of transdermal drug delivery. Research in this area is active both in the academic and industry settings. Ironically, only about 40 transdermal products with distinct active pharmaceutical ingredients are in the market indicating that more needs to be done to chronicle recent advances made in this area and to elucidate the mechanisms involved. This book will be helpful to researchers in the pharmaceutical and biotechnological industries as well as academics and graduate students working in the field of transdermal drug delivery and professionals working in the field of regulatory affairs focusing on topical and transdermal drug delivery systems. Researchers in the cosmetic and cosmeceutical industries, as well as those in chemical and biological engineering, will also find this book useful. Captures the most recent advancements and challenges in the field of transdermal drug delivery Covers both passive and active transdermal drug delivery strategies Explores a selection of state-of-the-art transdermal drug delivery systems
Author : José Juan Escobar-Chávez
Publisher : Bentham Science Publishers
ISBN 13 : 1608051919
Total Pages : 155 pages
Book Rating : 4.6/5 (8 download)
Download or read book Current Technologies To Increase The Transdermal Delivery Of Drugs written by José Juan Escobar-Chávez and published by Bentham Science Publishers. This book was released on 2010 with total page 155 pages. Available in PDF, EPUB and Kindle. Book excerpt: This e-book provides an overview of current technologies used to increase the topical/transdermal delivery of drugs, its protocols, advantages and limitations. It includes exclusive chapters on chemical enhancers, Iontophoresis, Sonophoresis, Electroporation, Microneedles and the more recent use of micro/nanoparticles to deliver drugs throughout the skin. The e-book's generalized approach on the topic is aimed to be helpful in drug discovery, drug delivery and toxicological research and to provide a broader perspective on the topic to readers with respect to current literature available on the.
Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 030967218X
Total Pages : 353 pages
Book Rating : 4.3/5 (96 download)
Download or read book Compounded Topical Pain Creams written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2020-07-21 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pain is both a symptom and a disease. It manifests in multiple forms and its treatment is complex. Physical, social, economic, and emotional consequences of pain can impair an individual's overall health, well-being, productivity, and relationships in myriad ways. The impact of pain at a population level is vast and, while estimates differ, the Centers for Disease Control and Prevention reported that 50 million U.S. adults are living in pain. In terms of pain's global impact, estimates suggest the problem affects approximately 1 in 5 adults across the world, with nearly 1 in 10 adults newly diagnosed with chronic pain each year. In recent years, the issues surrounding the complexity of pain management have contributed to increased demand for alternative strategies for treating pain. One such strategy is to expand use of topical pain medicationsâ€"medications applied to intact skin. This nonoral route of administration for pain medication has the potential benefit, in theory, of local activity and fewer systemic side effects. Compounding is an age-old pharmaceutical practice of combining, mixing, or adjusting ingredients to create a tailored medication to meet the needs of a patient. The aim of compounding, historically, has been to provide patients with access to therapeutic alternatives that are safe and effective, especially for people with clinical needs that cannot otherwise be met by commercially available FDA-approved drugs. Compounded Topical Pain Creams explores issues regarding the safety and effectiveness of the ingredients in these pain creams. This report analyzes the available scientific data relating to the ingredients used in compounded topical pain creams and offers recommendations regarding the treatment of patients.
Author : José Juan Escobar-Chávez
Publisher : Bentham Science Publishers
ISBN 13 : 1681083639
Total Pages : 342 pages
Book Rating : 4.6/5 (81 download)
Download or read book Physical Penetration Enhancers: Therapeutic Applications and Devices written by José Juan Escobar-Chávez and published by Bentham Science Publishers. This book was released on 2016-11-24 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume covers the methods of using skin penetrating agents, the therapeutic applications of physical penetration enhancers and devices in the market. Chapters cover topics such as transdermal drug delivery through iontophoresis, gene therapy, physiotherapy, skin disorders, vaccination, and pharmacology. Devices covered in this volume include micro needles, nano-carrier and gene delivery systems. This volume is a handy resource for professionals in medicine (dermatologists), biopharmacy, pharmaceutical technology, drug design and development (scientists and pharmaceutical R&D executives).
Author : Abialbon Paul
Publisher : Springer Nature
ISBN 13 : 9813360097
Total Pages : 1156 pages
Book Rating : 4.8/5 (133 download)
Download or read book Introduction to Basics of Pharmacology and Toxicology written by Abialbon Paul and published by Springer Nature. This book was released on 2021-03-13 with total page 1156 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explains the pharmacological relationships between the various systems in the human body. It offers a comprehensive overview of the pharmacology concerning the autonomic, central, and peripheral nervous systems. Presenting up-to-date information on chemical mediators and their significance, it highlights the therapeutic aspects of several diseases affecting the cardiovascular, renal, respiratory, gastrointestinal, endocrinal, and hematopoietic systems. The book also includes drug therapy for microbial and neoplastic diseases. It also comprises sections on immunopharmacology, dermatological, and ocular pharmacology providing valuable insights into these emerging and recent topics. Covering the diverse groups of drugs acting on different systems, the book reviews their actions, clinical uses, adverse effects, interactions, and subcellular mechanisms of action. It is divided into 11 parts, subdivided into several chapters that evaluate the basic pharmacological principles that govern the different types of body systems. This book is intended for academicians, researchers, and clinicians in industry and academic institutions in pharmaceutical, pharmacological sciences, pharmacy, medical sciences, physiology, neurosciences, biochemistry, molecular biology and other allied health sciences.
Author : Jonathan Hadgraft
Publisher : CRC Press
ISBN 13 : 0203909682
Total Pages : 400 pages
Book Rating : 4.2/5 (39 download)
Download or read book Transdermal Drug Delivery Systems written by Jonathan Hadgraft and published by CRC Press. This book was released on 2002-10-29 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents authoritative state-of-the-art discussions of the key issues pertinent to transdermal drug delivery, examining those topics necessary to enable a critical evaluation of a drug candidate's potential to be delivered across the skin; from physical chemistry and assessment of drug permeability to available enhancement technolgies, to regulator
Author : Heather A. E. Benson
Publisher : John Wiley & Sons
ISBN 13 : 1119769604
Total Pages : 580 pages
Book Rating : 4.1/5 (197 download)
Download or read book Fundamentals of Drug Delivery written by Heather A. E. Benson and published by John Wiley & Sons. This book was released on 2021-10-12 with total page 580 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive guide to the current research, major challenges, and future prospects of controlled drug delivery systems Controlled drug delivery has the potential to significantly improve therapeutic outcomes, increase clinical benefits, and enhance the safety of drugs in a wide range of diseases and health conditions. Fundamentals of Drug Delivery provides comprehensive and up-to-date coverage of the essential principles and processes of modern controlled drug delivery systems. Featuring contributions by respected researchers, clinicians, and pharmaceutical industry professionals, this edited volume reviews the latest research in the field and addresses the many issues central to the development of effective, controlled drug delivery. Divided in three parts, the book begins by introducing the concept of drug delivery and discussing both challenges and opportunities within the rapidly evolving field. The second section presents an in-depth critique of the common administration routes for controlled drug delivery, including delivery through skin, the lungs, and via ocular, nasal, and otic routes. The concluding section summarizes the current state of the field and examines specific issues in drug delivery and advanced delivery technologies, such as the use of nanotechnology in dermal drug delivery and advanced drug delivery systems for biologics. This authoritative resource: Covers each main stage of the drug development process, including selecting pharmaceutical candidates and evaluating their physicochemical characteristics Describes the role and application of mathematical modelling and the influence of drug transporters in pharmacokinetics and drug disposition Details the physiology and barriers to drug delivery for each administration route Presents a historical perspective and a look into the possible future of advanced drug delivery systems Explores nanotechnology and cell-mediated drug delivery, including applications for targeted delivery and toxicological and safety issues Includes comprehensive references and links to the primary literature Edited by a team of of internationally-recognized experts, Fundamentals of Drug Delivery is essential reading for researchers, industrial scientists, and advanced students in all areas of drug delivery including pharmaceutics, pharmaceutical sciences, biomedical engineering, polymer and materials science, and chemical and biochemical engineering.
Author : Ryan F. Donnelly
Publisher : John Wiley & Sons
ISBN 13 : 1118734491
Total Pages : 290 pages
Book Rating : 4.1/5 (187 download)
Download or read book Novel Delivery Systems for Transdermal and Intradermal Drug Delivery written by Ryan F. Donnelly and published by John Wiley & Sons. This book was released on 2015-09-21 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: This research book covers the major aspects relating to the use of novel delivery systems in enhancing both transdermal and intradermal drug delivery. It provides a review of transdermal and intradermal drug delivery, including the history of the field and the various methods employed to produce delivery systems from different materials such as device design, construction and evaluation, so as to provide a sound background to the use of novel systems in enhanced delivery applications. Furthermore, it presents in-depth analyses of recent developments in this exponentially growing field, with a focus on microneedle arrays, needle-free injections, nanoparticulate systems and peptide-carrier-type systems. It also covers conventional physical enhancement strategies, such as tape-stripping, sonophoresis, iontophoresis, electroporation and thermal/suction/laser ablation Discussions about the penetration of the stratum corneum by the various novel strategies highlight the importance of the application method. Comprehensive and critical reviews of transdermal and intradermal delivery research using such systems focus on the outcomes of in vivoanimal and human studies. The book includes laboratory, clinical and commercial case studies featuring safety and patient acceptability studies carried out to date, and depicts a growing area for use of these novel systems is in intradermal vaccine delivery. The final chapters review recent patents in this field and describe the work ongoing in industry.
Author : Eric Wane Smith
Publisher : CRC Press
ISBN 13 : 1420039202
Total Pages : 448 pages
Book Rating : 4.4/5 (2 download)
Download or read book Percutaneous Penetration Enhancers written by Eric Wane Smith and published by CRC Press. This book was released on 2005-11-02 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thoroughly updated, this second edition is the most comprehensive reference on the methods available for the enhancement of percutaneous penetration. The book examines a broad scope of chemical enhancers and various physical methods of enhancement. The range of chemicals discussed is, arguably, unsurpassed anywhere in the literature. This edition contains comprehensive descriptions of the latest techniques and several chapters cover the modern analytical techniques adapted to assess and measure penetration enhancement. New to this volume are chapters addressing penetration retardation, important for substances such as sunscreen agents, for which skin penetration is not desirable.
Author : Nina Dragicevic
Publisher : Springer
ISBN 13 : 9783662478615
Total Pages : 376 pages
Book Rating : 4.4/5 (786 download)
Download or read book Percutaneous Penetration Enhancers Chemical Methods in Penetration Enhancement written by Nina Dragicevic and published by Springer. This book was released on 2015-11-01 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: Percutaneous Penetration Enhancers in a mini-series format comprising five volumes, represents the most comprehensive reference on enhancement methods – both well established and recently introduced – in the field of dermal/transdermal drug delivery. In detail the broad range of both chemical and physical methods used to enhance the skin delivery of drugs is described. All aspects of drug delivery and measurement of penetration are covered and the latest findings are provided on skin structure and function, mathematics in skin permeation and modern analytical techniques adapted to assess and measure penetration. In offering a detailed description of the methods currently in use for penetration enhancement, this book will be of value for researchers, pharmaceutical scientists, practitioners and also students.
Author : Jaspreet Singh Kochhar
Publisher : Springer
ISBN 13 : 3030154440
Total Pages : 156 pages
Book Rating : 4.0/5 (31 download)
Download or read book Microneedles for Transdermal Drug Delivery written by Jaspreet Singh Kochhar and published by Springer. This book was released on 2019-07-04 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph covers a novel technology to deliver drugs and cosmetics through the skin in a minimally invasive manner. Microneedles – a bed of miniaturized needles is one of the most studied topics in delivering actives through the skin barrier. This book enables readers to understand the delivery of ingredients through the skin, describes a novel and simple method to fabricate microneedles containing a range of small and large molecular weight compounds, studies their physical properties as well as delivery through the skin layers. Readers will discover this book to be extremely beneficial to help them understand the state of the field of transdermal drug delivery, with extensive coverage including experimental data on basics of microneedle fabrication technology using photolithography, encapsulation of drugs within the polymeric matrix of microneedles and studying their release patternsin vitro and ex vivo . Academic researchers, pharmaceutical and cosmeceutical industry as well as students of skin science will find this account very useful in their pursuits. As microneedles grow and develop into a commercial reality with more actives being delivered and significant clinical research being put in, this account will hold well in providing basic principles and knowledge together with rigorous experimental data.
Author : Agis F. Kydonieus
Publisher : Springer
ISBN 13 :
Total Pages : 176 pages
Book Rating : 4.3/5 (91 download)
Download or read book Transdermal Delivery of Drugs written by Agis F. Kydonieus and published by Springer. This book was released on 1987 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt:
