Philosophy Of Systems Biology

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Philosophy of Systems Biology

Author : Sara Green
Publisher : Springer
ISBN 13 : 3319470000
Total Pages : 274 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Philosophy of Systems Biology by : Sara Green

Download or read book Philosophy of Systems Biology written by Sara Green and published by Springer. This book was released on 2016-12-15 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: The emergence of systems biology raises many fascinating questions: What does it mean to take a systems approach to problems in biology? To what extent is the use of mathematical and computational modelling changing the life sciences? How does the availability of big data influence research practices? What are the major challenges for biomedical research in the years to come? This book addresses such questions of relevance not only to philosophers and biologists but also to readers interested in the broader implications of systems biology for science and society. The book features reflections and original work by experts from across the disciplines including systems biologists, philosophers, and interdisciplinary scholars investigating the social and educational aspects of systems biology. In response to the same set of questions, the experts develop and defend their personal perspectives on the distinctive character of systems biology and the challenges that lie ahead. Readers are invited to engage with different views on the questions addressed, and may explore numerous themes relating to the philosophy of systems biology. This edited work will appeal to scholars and all levels, from undergraduates to researchers, and to those interested in a variety of scholarly approaches such as systems biology, mathematical and computational modelling, cell and molecular biology, genomics, systems theory, and of course, philosophy of biology.

Systems Biology

Author : Fred Boogerd
Publisher : Elsevier
ISBN 13 : 0080475272
Total Pages : 361 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Systems Biology by : Fred Boogerd

Download or read book Systems Biology written by Fred Boogerd and published by Elsevier. This book was released on 2007-03-20 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: Systems biology is a vigorous and expanding discipline, in many ways a successor to genomics and perhaps unprecedented in its combination of biology with a great many other sciences, from physics to ecology, from mathematics to medicine, and from philosophy to chemistry. Studying the philosophical foundations of systems biology may resolve a longer standing issue, i.e., the extent to which Biology is entitled to its own scientific foundations rather than being dominated by existing philosophies. * Answers the question of what distinguishes the living from the non-living* An in-depth look to a vigorous and expanding discipline, from molecule to system* Explores the region between individual components and the system

Systems Biology

Author : Fred C. Boogerd
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (12 download)

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Book Synopsis Systems Biology by : Fred C. Boogerd

Download or read book Systems Biology written by Fred C. Boogerd and published by . This book was released on 2007 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Philosophy of Biology

Author : Peter Godfrey-Smith
Publisher : Princeton University Press
ISBN 13 : 0691174679
Total Pages : 200 pages
Book Rating : 4.6/5 (911 download)

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Book Synopsis Philosophy of Biology by : Peter Godfrey-Smith

Download or read book Philosophy of Biology written by Peter Godfrey-Smith and published by Princeton University Press. This book was released on 2016-09-06 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: An essential introduction to the philosophy of biology This is a concise, comprehensive, and accessible introduction to the philosophy of biology written by a leading authority on the subject. Geared to philosophers, biologists, and students of both, the book provides sophisticated and innovative coverage of the central topics and many of the latest developments in the field. Emphasizing connections between biological theories and other areas of philosophy, and carefully explaining both philosophical and biological terms, Peter Godfrey-Smith discusses the relation between philosophy and science; examines the role of laws, mechanistic explanation, and idealized models in biological theories; describes evolution by natural selection; and assesses attempts to extend Darwin's mechanism to explain changes in ideas, culture, and other phenomena. Further topics include functions and teleology, individuality and organisms, species, the tree of life, and human nature. The book closes with detailed, cutting-edge treatments of the evolution of cooperation, of information in biology, and of the role of communication in living systems at all scales. Authoritative and up-to-date, this is an essential guide for anyone interested in the important philosophical issues raised by the biological sciences.

The Philosophy of Biology

Author : Kostas Kampourakis
Publisher : Springer Science & Business Media
ISBN 13 : 9400765371
Total Pages : 765 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis The Philosophy of Biology by : Kostas Kampourakis

Download or read book The Philosophy of Biology written by Kostas Kampourakis and published by Springer Science & Business Media. This book was released on 2013-06-18 with total page 765 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book brings together for the first time philosophers of biology to write about some of the most central concepts and issues in their field from the perspective of biology education. The chapters of the book cover a variety of topics ranging from traditional ones, such as biological explanation, biology and religion or biology and ethics, to contemporary ones, such as genomics, systems biology or evolutionary developmental biology. Each of the 30 chapters covers the respective philosophical literature in detail and makes specific suggestions for biology education. The aim of this book is to inform biology educators, undergraduate and graduate students in biology and related fields, students in teacher training programs, and curriculum developers about the current state of discussion on the major topics in the philosophy of biology and its implications for teaching biology. In addition, the book can be valuable to philosophers of biology as an introductory text in undergraduate and graduate courses.

Philosophy of Complex Systems

Author :
Publisher : Elsevier
ISBN 13 : 0080931227
Total Pages : 951 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Philosophy of Complex Systems by :

Download or read book Philosophy of Complex Systems written by and published by Elsevier. This book was released on 2011-05-23 with total page 951 pages. Available in PDF, EPUB and Kindle. Book excerpt: The domain of nonlinear dynamical systems and its mathematical underpinnings has been developing exponentially for a century, the last 35 years seeing an outpouring of new ideas and applications and a concomitant confluence with ideas of complex systems and their applications from irreversible thermodynamics. A few examples are in meteorology, ecological dynamics, and social and economic dynamics. These new ideas have profound implications for our understanding and practice in domains involving complexity, predictability and determinism, equilibrium, control, planning, individuality, responsibility and so on.Our intention is to draw together in this volume, we believe for the first time, a comprehensive picture of the manifold philosophically interesting impacts of recent developments in understanding nonlinear systems and the unique aspects of their complexity. The book will focus specifically on the philosophical concepts, principles, judgments and problems distinctly raised by work in the domain of complex nonlinear dynamical systems, especially in recent years. -Comprehensive coverage of all main theories in the philosophy of Complex Systems -Clearly written expositions of fundamental ideas and concepts -Definitive discussions by leading researchers in the field -Summaries of leading-edge research in related fields are also included

Bioinformatics for Systems Biology

Author : Stephen Krawetz
Publisher : Springer Science & Business Media
ISBN 13 : 1597454400
Total Pages : 623 pages
Book Rating : 4.5/5 (974 download)

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Book Synopsis Bioinformatics for Systems Biology by : Stephen Krawetz

Download or read book Bioinformatics for Systems Biology written by Stephen Krawetz and published by Springer Science & Business Media. This book was released on 2008-12-11 with total page 623 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioinformatics for Systems Biology bridges and unifies many disciplines. It presents the life scientist, computational biologist, and mathematician with a common framework. Only by linking the groups together may the true life sciences revolution move forward.

Philosophy of Biology

Author : Brian Garvey
Publisher : Routledge
ISBN 13 : 1317493672
Total Pages : 289 pages
Book Rating : 4.3/5 (174 download)

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Book Synopsis Philosophy of Biology by : Brian Garvey

Download or read book Philosophy of Biology written by Brian Garvey and published by Routledge. This book was released on 2014-12-05 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: This major new series in the philosophy of science aims to provide a new generation of textbooks for the subject. The series will not only offer fresh treatments of core topics in the theory and methodology of scientific knowledge, but also introductions to newer areas of the discipline. Furthermore, the series will cover topics in current science that raise significant foundational issues both for scientific theory and for philosophy more generally. Biology raises distinct questions of its own not only for philosophy of science, but for metaphysics, epistemology and ethics. This comprehensive new textbook for a rapidly growing field of study provides students new to the subject with an up-to-date presentation of the key philosophical issues. Care is taken throughout to keep the technicalities accessible to the non-biologist but without sacrificing the philosophical subtleties. The first part of the book covers the philosophical challenges posed by evolution and evolutionary biology, beginning with Darwin's central argument in the Origin of the Species. Individual chapters cover natural selection, the selfish gene, alternative units of selection, developmental systems theory, adaptionism and issues in macroevolution. The second part of the book examines philosophical questions arising in connection with biological traits, function, nature and nurture, and biological kinds. The third part of the book examines metaphysical questions, biology's relation with the traditional concerns of philosophy of science, and how evolution has been introduced into epistemological debates. The final part considers the relevance of biology to questions about ethics, religion and human nature.

The Multiple Realization Book

Author : Thomas W. Polger
Publisher : Oxford University Press
ISBN 13 : 0198732899
Total Pages : 273 pages
Book Rating : 4.1/5 (987 download)

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Book Synopsis The Multiple Realization Book by : Thomas W. Polger

Download or read book The Multiple Realization Book written by Thomas W. Polger and published by Oxford University Press. This book was released on 2016 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thomas W. Polger and Lawrence A. Shapiro offer the first full investigation of multiple realization--the idea that minds can be realized in ways other than the human brain. They cast doubt on the hypothesis and offer an alternative framework for understanding explanations in the cognitive sciences, and in chemistry, biology, and related fields.

Contextualizing Systems Biology

Author : Martin Döring
Publisher : Springer
ISBN 13 : 3319171062
Total Pages : 325 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Contextualizing Systems Biology by : Martin Döring

Download or read book Contextualizing Systems Biology written by Martin Döring and published by Springer. This book was released on 2015-12-18 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: This collective monograph aims at contributing to an improved understanding of the epistemic presumptions, sociocultural implications and historically backgrounds of the newly emerging and currently expanding approach of systems biology. In doing so, it offers empirically grounded, valuable and reflexive information about a paradigmatic shift in the biosciences for a wide range of scientists working in the interdisciplinary areas of systems biology, synthetic biology, molecular biology, biology, the philosophy of science, the sociology of science and scientific knowledge, science and technology studies, technology assessment and the like. The authors of this monograph share the theoretical methodological premise that science is a culturally and socially embedded practice which characterizes our culture as a scientific one and at the same time draws its innovative potential from its socio-cultural context. This dialectic relationship lies at the heart of the current development of systems biology which is conceived as a so-called successor of ‘-omics’ research and triggered by high-throughput information technologies. At the same time a need for a holistic conceptualization of complex biological processes emerges. The title Contextualizing Systems Biology suggests that this book analyzes the development and advent of systems biology from different theoretical and methodological perspectives. We investigate a variety of contexts ranging from the analysis of cognitive contexts (such as basic theoretical concepts) to regulative contexts (policies) to the concrete application of a systems biology in the socio-scientific context of a European research project. In empirically analyzing these different and interrelated layers and dimensions of systems biology, the scope of the book goes beyond present attempts to investigate the advent of new approaches in the biological sciences as it frames and assesses systems biology from an interdisciplinary and integrated perspective.

Recent Advances in Systems Biology Research

Author : A. X. C. N. Valente
Publisher : Nova Science Publishers
ISBN 13 : 9781629487366
Total Pages : 0 pages
Book Rating : 4.4/5 (873 download)

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Book Synopsis Recent Advances in Systems Biology Research by : A. X. C. N. Valente

Download or read book Recent Advances in Systems Biology Research written by A. X. C. N. Valente and published by Nova Science Publishers. This book was released on 2014 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Driven by rapid developments in protein and DNA sequencing technologies, systems biology has become an important research paradigm. It is marked by an emphasis on integrating data on multiple scales and creating a framework for developing predictive models that are valid across the spectrum of structural hierarchies found in biological systems. This book consists of fourteen original chapters and an introduction that together provide a comprehensive introduction to the subject starting from discussions of its definition and scope and ending in detailed reviews of how the systems approach is affecting clinical research and practice. Most chapters are written to be accessible to a wide readership and contain references to the latest research. Altogether, this is a state-of-the-art description of the present and future of systems biology.

Philosophy of Biology Before Biology

Author : Cécilia Bognon-Küss
Publisher : Routledge
ISBN 13 : 1317227557
Total Pages : 220 pages
Book Rating : 4.3/5 (172 download)

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Book Synopsis Philosophy of Biology Before Biology by : Cécilia Bognon-Küss

Download or read book Philosophy of Biology Before Biology written by Cécilia Bognon-Küss and published by Routledge. This book was released on 2019-02-11 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of the term "biology" to refer to a unified science of life emerged around 1800 (most prominently by scientists such as Lamarck and Treviranus, although scholarship has indicated its usage at least 30-40 years earlier). The interplay between philosophy and natural science has also accompanied the constitution of biology as a science. Philosophy of Biology Before Biology examines biological and protobiological writings from the mid-eighteenth century to the early nineteenth century (from Buffon to Cuvier; Kant to Oken; and Kielmeyer) with two major sets of questions in mind: What were the distinctive conceptual features of the move toward biology as a science? What were the relations and differences between the "philosophical" focus on the nature of living entities, and the "scientific" focus? This insightful volume produces a fresh but also systematic perspective both on the history of biology as a science and on the early versions of, in the 1960s in a post-positivist context, the philosophy of biology. It will appeal to students and researchers interested in fields such as history of science, philosophy of science and biology.

Biological Autonomy

Author : Alvaro Moreno
Publisher : Springer
ISBN 13 : 9401798370
Total Pages : 249 pages
Book Rating : 4.4/5 (17 download)

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Book Synopsis Biological Autonomy by : Alvaro Moreno

Download or read book Biological Autonomy written by Alvaro Moreno and published by Springer. This book was released on 2015-05-04 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since Darwin, Biology has been framed on the idea of evolution by natural selection, which has profoundly influenced the scientific and philosophical comprehension of biological phenomena and of our place in Nature. This book argues that contemporary biology should progress towards and revolve around an even more fundamental idea, that of autonomy. Biological autonomy describes living organisms as organised systems, which are able to self-produce and self-maintain as integrated entities, to establish their own goals and norms, and to promote the conditions of their existence through their interactions with the environment. Topics covered in this book include organisation and biological emergence, organisms, agency, levels of autonomy, cognition, and a look at the historical dimension of autonomy. The current development of scientific investigations on autonomous organisation calls for a theoretical and philosophical analysis. This can contribute to the elaboration of an original understanding of life - including human life - on Earth, opening new perspectives and enabling fecund interactions with other existing theories and approaches. This book takes up the challenge.

From Systems Biology to Systems Medicine

Author : James A. Marcum
Publisher :
ISBN 13 : 9781536179606
Total Pages : 252 pages
Book Rating : 4.1/5 (796 download)

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Book Synopsis From Systems Biology to Systems Medicine by : James A. Marcum

Download or read book From Systems Biology to Systems Medicine written by James A. Marcum and published by . This book was released on 2020-07-09 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: Throughout most of the twentieth century, the biomedical model dominated healthcare. However, the biomedical model had its critics, who proposed alternative models to replace it. Eventually, biomedicine became fragmented at its foundations with a variety of approaches to its nature and practice. Medicine's current response to this fragmentation is to combine these disparate approaches into a single system--systems medicine. In the present book, I examine the shift, during the postgenomics era, from the biomedical model to systems medicine vis-à-vis systems biology, as well as the challenges facing systems medicine's implementation in the twenty-first century. The main goal of the present book is to provide a disciplinary framework for examining the rise of systems medicine, especially in terms of the incorporation of systems biology into the biomedical model. To realize that goal, the following questions are addressed. What is a disciplinary framework? And, why is this framework important for understanding systems biology and medicine? Briefly, a disciplinary framework represents the relational structure among disparate disciplines that support and ground a discipline and its corpus. For traditional biology and medicine, that framework consists of various disciplines within the biological and biomedical sciences, including physiology, neuroscience, pathology, and epidemiology--to name a few. For the present purpose, systems biology within the last several decades is reshaping the disciplinary framework of the biological and biomedical sciences, which is also responsible for the emergence of systems medicine. In addition, the challenges facing systems medicine, especially its operationalization and implementation with respect to medical education and practice, as well as research, are also explored.

Learning and Inference in Computational Systems Biology

Author : Neil D. Lawrence
Publisher :
ISBN 13 :
Total Pages : 384 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Learning and Inference in Computational Systems Biology by : Neil D. Lawrence

Download or read book Learning and Inference in Computational Systems Biology written by Neil D. Lawrence and published by . This book was released on 2010 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tools and techniques for biological inference problems at scales ranging from genome-wide to pathway-specific. Computational systems biology unifies the mechanistic approach of systems biology with the data-driven approach of computational biology. Computational systems biology aims to develop algorithms that uncover the structure and parameterization of the underlying mechanistic model--in other words, to answer specific questions about the underlying mechanisms of a biological system--in a process that can be thought of as learning or inference. This volume offers state-of-the-art perspectives from computational biology, statistics, modeling, and machine learning on new methodologies for learning and inference in biological networks.The chapters offer practical approaches to biological inference problems ranging from genome-wide inference of genetic regulation to pathway-specific studies. Both deterministic models (based on ordinary differential equations) and stochastic models (which anticipate the increasing availability of data from small populations of cells) are considered. Several chapters emphasize Bayesian inference, so the editors have included an introduction to the philosophy of the Bayesian approach and an overview of current work on Bayesian inference. Taken together, the methods discussed by the experts in Learning and Inference in Computational Systems Biology provide a foundation upon which the next decade of research in systems biology can be built. Florence d'Alch e-Buc, John Angus, Matthew J. Beal, Nicholas Brunel, Ben Calderhead, Pei Gao, Mark Girolami, Andrew Golightly, Dirk Husmeier, Johannes Jaeger, Neil D. Lawrence, Juan Li, Kuang Lin, Pedro Mendes, Nicholas A. M. Monk, Eric Mjolsness, Manfred Opper, Claudia Rangel, Magnus Rattray, Andreas Ruttor, Guido Sanguinetti, Michalis Titsias, Vladislav Vyshemirsky, David L. Wild, Darren Wilkinson, Guy Yosiphon

Philosophical Perspectives on the Engineering Approach in Biology

Author : Sune Holm
Publisher : Taylor & Francis
ISBN 13 : 1351212230
Total Pages : 217 pages
Book Rating : 4.3/5 (512 download)

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Book Synopsis Philosophical Perspectives on the Engineering Approach in Biology by : Sune Holm

Download or read book Philosophical Perspectives on the Engineering Approach in Biology written by Sune Holm and published by Taylor & Francis. This book was released on 2020-06-07 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: Philosophical Perspectives on the Engineering Approach in Biology provides a philosophical examination of what has been called the most powerful metaphor in biology: The machine metaphor. The chapters collected in this volume discuss the idea that living systems can be understood through the lens of engineering methods and machine metaphors from both historical, theoretical, and practical perspectives. In their contributions the authors examine questions about scientific explanation and methodology, the interrelationship between science and engineering, and the impact that the use of engineering metaphors in science may have for bioethics and science communication, such as the worry that its wide application reinforces public misconceptions of the nature of new biotechnology and biological life. The book also contains an introduction that describes the rise of the machine analogy and the many ways in which it plays a central role in fundamental debates about e.g. design, adaptation, and reductionism in the philosophy of biology. The book will be useful as a core reading for professionals as well as graduate and undergraduate students in courses of philosophy of science and for life scientists taking courses in philosophy of science and bioethics.

Biology, History, and Natural Philosophy

Author : A. D. Breck
Publisher : Springer Science & Business Media
ISBN 13 : 146841965X
Total Pages : 360 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Biology, History, and Natural Philosophy by : A. D. Breck

Download or read book Biology, History, and Natural Philosophy written by A. D. Breck and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: In a world that peers over the brink of disaster more often than not it is difficul t to find specific assignments for the scholarly community. One speaks of peace and brotherhood only to realize that for many the only real hope of making a contribution may seem to be in a field of scientific specialization seemingly irrelevant to social causes and problems. Yet the history of man since the beginnings of science in the days of the Greeks does not support this gloomy thesis. Time and again we have seen science precipitate social trends or changes in the humanistic beliefs that have a significant effect on. the scientific community. Not infrequently the theoretical scientist, triggered by society's changing goals and understandings, finds ultimate satisfaction in the work of his colleagues in engineering and the other applied fields. Thus the major debate in mid-nineteenth century in which the evidence of natural history and geology at variance with the Biblical feats provided not only courage to a timid Darwin but the kind of audience that was needed to fit his theories into the broad public dialogue on these topics. The impact of "Darwinism" was felt far beyond the scientific community. It affected social thought, upset religious certainties and greatly affected the teaching of science.