Spheroids in Cancer Research

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Publisher : Springer Science & Business Media
ISBN 13 : 3642823408
Total Pages : 328 pages
Book Rating : 4.6/5 (428 download)

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Book Synopsis Spheroids in Cancer Research by : H. Acker

Download or read book Spheroids in Cancer Research written by H. Acker and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Malignant growth of cells is often characterized by disorganization of tissue structure, abnormal blood vessel development, and insuffi cient vascular supply. As a consequence, the cancer cells grow in a three-dimensional pattern in atypical microenvironments which include physical, chemical, and nutritional stresses. Necrosis often develops some distance away from the blood vessels. In association with an inherent instability in malignant cell populations, and also because of the changing micromilieu, significant cellular heteroge neity emerges with regard to various phenotypic characteristics. Both biological behavior and responses to therapeutic agents can be affected. A variety of in vitro and in vivo experimental models exist for research on properties of cancer cells during growth. The multicell spheroid model was developed as a system of intermediate complexity in which three dimensional growth of cells enhances cell-cell interactions and creates micro environments that simulate the conditions in intervascular microregions of tumors or microme tastatic foci. Spheroids may change their cellular characteristics with changing environments during growth. These can be studied under controlled conditions in vitro. Interest in details of experimental methods for this model system stimulated the organization of the First International Conference in Rochester, NY in 1980, the Proceedings of which were summarized in Cancer Research in 1981. Since then there has been a rapid increase in the use of this model system, and increased research on the significance of cell-cell and cell-microenvironment interactions in biology in general.

Perspectives in cancer research and treatment

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Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (164 download)

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Book Synopsis Perspectives in cancer research and treatment by : David Pressman

Download or read book Perspectives in cancer research and treatment written by David Pressman and published by . This book was released on 1973 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Perspectives in Cancer Research and Treatment Contributions in Honor of the 75. Anniversary of the Roswell Park Memorial Inst

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Publisher :
ISBN 13 :
Total Pages : 413 pages
Book Rating : 4.:/5 (17 download)

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Book Synopsis Perspectives in Cancer Research and Treatment Contributions in Honor of the 75. Anniversary of the Roswell Park Memorial Inst by :

Download or read book Perspectives in Cancer Research and Treatment Contributions in Honor of the 75. Anniversary of the Roswell Park Memorial Inst written by and published by . This book was released on 1973 with total page 413 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cancer Patients, Cancer Pathways

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Publisher : Springer
ISBN 13 : 1137272082
Total Pages : 281 pages
Book Rating : 4.1/5 (372 download)

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Book Synopsis Cancer Patients, Cancer Pathways by : C. Timmermann

Download or read book Cancer Patients, Cancer Pathways written by C. Timmermann and published by Springer. This book was released on 2012-10-10 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: Eleven essays by historians and sociologists examine cancer research and treatment as everyday practice in post-war Europe and North America. These are not stories of inevitable medical progress and obstacles overcome, but of historical contingencies, cultural differences, hope, and often disappointed expectations.

Perspectives in Cancer Research and Treatment

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Author :
Publisher : Alan R. Liss
ISBN 13 :
Total Pages : 440 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Perspectives in Cancer Research and Treatment by : Gerald Patrick Murphy

Download or read book Perspectives in Cancer Research and Treatment written by Gerald Patrick Murphy and published by Alan R. Liss. This book was released on 1973 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt:

New Perspectives in Cancer Research and Therapy

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Publisher :
ISBN 13 : 9788130800028
Total Pages : 432 pages
Book Rating : 4.8/5 ( download)

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Book Synopsis New Perspectives in Cancer Research and Therapy by : Shigeki Kuriyama

Download or read book New Perspectives in Cancer Research and Therapy written by Shigeki Kuriyama and published by . This book was released on 2005-01-01 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Perspectives in Cancer Prevention-Translational Cancer Research

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Publisher : Springer Science & Business Media
ISBN 13 : 8132215338
Total Pages : 173 pages
Book Rating : 4.1/5 (322 download)

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Book Synopsis Perspectives in Cancer Prevention-Translational Cancer Research by : Perumana R. Sudhakaran

Download or read book Perspectives in Cancer Prevention-Translational Cancer Research written by Perumana R. Sudhakaran and published by Springer Science & Business Media. This book was released on 2013-10-25 with total page 173 pages. Available in PDF, EPUB and Kindle. Book excerpt: Being a complex disease that affects millions of people world over, cancer research has assumed great significance. Translational cancer research transforms scientific discoveries in the laboratory or population studies into clinical application to reduce incidence of cancer , morbidity and mortality. It is becoming increasingly evident that cancer is a preventable disease. The IVth International Symposium on Translational Cancer Research held in Udaipur, India in December 2011, discussed various aspects of the biological processes in cancer cells and approaches to cancer prevention. A few contributions from this meeting are presented in this book, providing an in depth analysis of data on cancer prevention and therapeutics. These contributions are either critical reviews or research reports. The topics discussed include evidence-based nutritional recommendations for cancer patients and survivors, risk factors such as stress, enrichment of tumour stem cells by anticancer drug treatment contributing to tumour recurrence and the mechanism of anticancer effects of various natural products. Chemosensitizing effect of curcumin, anti-cancer effect of products from neem, action of sulforaphane and cytotoxic effect of a number of novel synthetic coordination complexes of trace metals have been discussed. Novel molecular targets of angiogenesis and molecular basis of the gender bias to thyroid cancer have also been discussed . This book provides useful information on translational cancer research to clinicians and biomedical scientists.

Transforming Clinical Research in the United States

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Publisher : National Academies Press
ISBN 13 : 0309163358
Total Pages : 151 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Transforming Clinical Research in the United States by : Institute of Medicine

Download or read book Transforming Clinical Research in the United States written by Institute of Medicine and published by National Academies Press. This book was released on 2010-10-22 with total page 151 pages. Available in PDF, EPUB and Kindle. Book excerpt: An ideal health care system relies on efficiently generating timely, accurate evidence to deliver on its promise of diminishing the divide between clinical practice and research. There are growing indications, however, that the current health care system and the clinical research that guides medical decisions in the United States falls far short of this vision. The process of generating medical evidence through clinical trials in the United States is expensive and lengthy, includes a number of regulatory hurdles, and is based on a limited infrastructure. The link between clinical research and medical progress is also frequently misunderstood or unsupported by both patients and providers. The focus of clinical research changes as diseases emerge and new treatments create cures for old conditions. As diseases evolve, the ultimate goal remains to speed new and improved medical treatments to patients throughout the world. To keep pace with rapidly changing health care demands, clinical research resources need to be organized and on hand to address the numerous health care questions that continually emerge. Improving the overall capacity of the clinical research enterprise will depend on ensuring that there is an adequate infrastructure in place to support the investigators who conduct research, the patients with real diseases who volunteer to participate in experimental research, and the institutions that organize and carry out the trials. To address these issues and better understand the current state of clinical research in the United States, the Institute of Medicine's (IOM) Forum on Drug Discovery, Development, and Translation held a 2-day workshop entitled Transforming Clinical Research in the United States. The workshop, summarized in this volume, laid the foundation for a broader initiative of the Forum addressing different aspects of clinical research. Future Forum plans include further examining regulatory, administrative, and structural barriers to the effective conduct of clinical research; developing a vision for a stable, continuously funded clinical research infrastructure in the United States; and considering strategies and collaborative activities to facilitate more robust public engagement in the clinical research enterprise.

Quality of Life

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Publisher : Jones & Bartlett Learning
ISBN 13 : 9780763722357
Total Pages : 576 pages
Book Rating : 4.7/5 (223 download)

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Book Synopsis Quality of Life by : Pamela S. Hinds

Download or read book Quality of Life written by Pamela S. Hinds and published by Jones & Bartlett Learning. This book was released on 2003 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Comprehensive Reference Provides A Unique Perspective On Quality Of Life Issues For Oncology Nurses In Education, Research, And Clinical Practice, And Presents Quality Of Life Issues Related To Specific Diseases, Treatments, And Populations.

Cancer Treatment and Research in Humanistic Perspective

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Publisher :
ISBN 13 :
Total Pages : 264 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Cancer Treatment and Research in Humanistic Perspective by : Steven C. Gross

Download or read book Cancer Treatment and Research in Humanistic Perspective written by Steven C. Gross and published by . This book was released on 1985 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cancer

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Publisher : John Wiley & Sons
ISBN 13 : 1118962885
Total Pages : 708 pages
Book Rating : 4.1/5 (189 download)

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Book Synopsis Cancer by : Gary S. Stein

Download or read book Cancer written by Gary S. Stein and published by John Wiley & Sons. This book was released on 2019-09-18 with total page 708 pages. Available in PDF, EPUB and Kindle. Book excerpt: A guide to recent insights into the genetic and epigenetic parameters of cancer biology and pathology and emerging clinical applications The thoroughly updated second edition of The Biology and Treatment of Cancer, now titled Cancer: Prevention, Early Detection, Treatment and Recovery, goes beyond reviewing the fundamental properties of cancer biology and the relevant issues associated with treatment of the disease. The new edition contains coverage of additional "patient centric" topics and presents cancer biology with selection of topics, facts, and perspectives written in easy-to-understand terms. With contributions from noted experts, the book explores recent advances in the understanding of cancer including breakthroughs in the molecular and cellular basis of cancer and provides strategies for approaching cancer prevention, early detection, and treatment. The authors incorporate recent information on the genetic and epigenetic parameters of cancer biology and pathology with indications of emerging clinical applications. The text offers a unique guide to cancer prevention, early detection, treatment, and recovery for students, caregivers, and most importantly cancer patients. This significant book: Incorporates current insight into the genetic and epigenetic parameters of cancer biology and pathology and information on emerging clinical applications Contains contributions from leaders in cancer research, care, and clinical trials Offers an accessible guide to an accurate and balanced understanding of cancer and the cancer patient Focuses on the importance of cancer prevention, early detection, treatment, and survivorship Written for medical students, students of cancer biology, and caregivers and cancer patients, Cancer: Prevention, Early Detection, Treatment and Recovery offers an authoritative overview of the challenges and opportunities associated with cancer biology, cancer research, and the spectrum of clinical considerations.

Medical Perspectives in Cancer Research

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Publisher : Wiley-VCH
ISBN 13 :
Total Pages : 312 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Medical Perspectives in Cancer Research by : A. J. S. Davies

Download or read book Medical Perspectives in Cancer Research written by A. J. S. Davies and published by Wiley-VCH. This book was released on 1985 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Assessing and Improving Value in Cancer Care

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Publisher : National Academies Press
ISBN 13 : 0309147336
Total Pages : 165 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Assessing and Improving Value in Cancer Care by : Institute of Medicine

Download or read book Assessing and Improving Value in Cancer Care written by Institute of Medicine and published by National Academies Press. This book was released on 2009-10-30 with total page 165 pages. Available in PDF, EPUB and Kindle. Book excerpt: Unlike many other areas in health care, the practice of oncology presents unique challenges that make assessing and improving value especially complex. First, patients and professionals feel a well-justified sense of urgency to treat for cure, and if cure is not possible, to extend life and reduce the burden of disease. Second, treatments are often both life sparing and highly toxic. Third, distinctive payment structures for cancer medicines are intertwined with practice. Fourth, providers often face tremendous pressure to apply the newest technologies to patients who fail to respond to established treatments, even when the evidence supporting those technologies is incomplete or uncertain, and providers may be reluctant to stop toxic treatments and move to palliation, even at the end of life. Finally, the newest and most novel treatments in oncology are among the most costly in medicine. This volume summarizes the results of a workshop that addressed these issues from multiple perspectives, including those of patients and patient advocates, providers, insurers, health care researchers, federal agencies, and industry. Its broad goal was to describe value in oncology in a complete and nuanced way, to better inform decisions regarding developing, evaluating, prescribing, and paying for cancer therapeutics.

Improving Outcomes for Breast Cancer Survivors

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Publisher : Springer
ISBN 13 : 3319163663
Total Pages : 280 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Improving Outcomes for Breast Cancer Survivors by : Patricia A. Ganz

Download or read book Improving Outcomes for Breast Cancer Survivors written by Patricia A. Ganz and published by Springer. This book was released on 2015-06-09 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: In collaboration with the Breast Cancer Research Foundation (BCRF), this timely volume provides a comprehensive review on all areas of breast cancer survivorship research, highlighting research that is underway or in development. The range of topics covered include the biology and management of fatigue and cognitive dysfunction on breast cancer survivorship, the biology and management of Neuropathy and Arthralgias, the ongoing research on the biology of diet and lifestyle interventions in survivors, and more. With the tremendous growth in the number of breast cancer survivors, researchers have moved beyond describing the outcomes of breast cancer treatments and are focusing their research on understanding the mechanisms underlying the development of the late effects of breast cancer treatment, as well as the development and evaluation of interventions to mitigate some of the persistent symptoms—topics which are also explored in this volume. In addition, current research on how to improve survivorship and reduce recurrence of breast cancer through behavioral and lifestyle modifications is also discussed.

Recent Advances in Cancer Research and Therapy

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Publisher : Elsevier
ISBN 13 : 012397836X
Total Pages : 701 pages
Book Rating : 4.1/5 (239 download)

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Book Synopsis Recent Advances in Cancer Research and Therapy by : Xin-Yuan Liu

Download or read book Recent Advances in Cancer Research and Therapy written by Xin-Yuan Liu and published by Elsevier. This book was released on 2012-05-18 with total page 701 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer continues to be one of the major causes of death throughout the developed world, which has led to increased research on effective treatments. Because of this, in the past decade, rapid progress in the field of cancer treatment has been seen. Recent Advances in Cancer Research and Therapy reviews in specific details some of the most effective and promising treatments developed in research centers worldwide. While referencing advances in traditional therapies and treatments such as chemotherapy, this book also highlights advances in biotherapy including research using Interferon and Super Interferon, HecI based and liposome based therapy, gene therapy, and p53 based cancer therapy. There is also a discussion of current cancer research in China including traditional Chinese medicine. Written by leading scientists in the field, this book provides an essential insight into the current state of cancer therapy and treatment. - Includes a wide range of research areas including a focus on biotherapy and the development of novel cancer therapeutic strategies. - Formatted for a broad audience including all working in researching cancer treatments and therapies. - Discusses special traits and results of Chinese cancer research.

An Omics Perspective on Cancer Research

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Publisher : Springer Science & Business Media
ISBN 13 : 9048126754
Total Pages : 269 pages
Book Rating : 4.0/5 (481 download)

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Book Synopsis An Omics Perspective on Cancer Research by : William C.S. Cho

Download or read book An Omics Perspective on Cancer Research written by William C.S. Cho and published by Springer Science & Business Media. This book was released on 2010-04-07 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: Omics is an emerging and exciting area in the field of science and medicine. Numerous promising developments have been elucidated using omics (including genomics, transcriptomics, epigenomics, proteomics, metabolomics, interactomics, cytomics and bioinformatics) in cancer research. The development of high-throughput technologies that permit the solution of deciphering cancer from higher dimensionality will provide a knowledge base which changes the face of cancer understanding and therapeutics. This is the first book to provide such a comprehensive coverage of a rapidly evolving area written by leading experts in the field of omics. It complies and details cutting-edge cancer research that covers the broad advances in the field and its application from cancer-associated gene discovery to drug target validation. It also highlights the potential of using integration approach for cancer research. This unique and timely book provides a thorough overview of developing omics, which will appeal to anyone involved in cancer research. It will be a useful reference book for graduate students of different subjects (medicine, biology, engineering, etc) and senior scientists interested in the fascinating area of advanced technologies in cancer research. Readership: This is a precious book for all types of readers – cancer researchers, oncologists, pathologists, biologists, clinical chemists, pharmacologists, pharmaceutical specialists, biostatisticians, and bioinformaticists who want to expand their knowledge in cancer research.

Perspectives on Cancer Care

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1444329324
Total Pages : 272 pages
Book Rating : 4.4/5 (443 download)

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Book Synopsis Perspectives on Cancer Care by : Tonks N. Fawcett

Download or read book Perspectives on Cancer Care written by Tonks N. Fawcett and published by John Wiley & Sons. This book was released on 2010-11-11 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: Perspectives on Cancer Care is a unique collection of insights from contributors, based on their specific expertise and experience. It provides a range of perspectives on cancer care to inspire readers and encourage high-quality care through an enhanced understanding of patients' needs and carers' skills. The book presents a series of chapters highlighting different circumstances and approaches to the complex reality of cancer care. In each chapter the author presents their own picture of their experience of the individual's needs and the care required to address these needs, illustrating the particular sensitivity, trust, empathy and support required in the care of patients with cancer and their families. The holistic approach to total care is a prominent feature in cancer care and this is illustrated throughout the various chapters. This collection of perspectives on cancer care: highlights particular issues in the field encourages best practice draws on the expertise of specialist practitioners in the field of cancer care features a holistic approach to cancer care, illustrated through scenarios