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Personalized Medicine And Neurosurgery
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Book Synopsis Personalized Medicine and Neurosurgery by : M. Yashar S. Kalani
Download or read book Personalized Medicine and Neurosurgery written by M. Yashar S. Kalani and published by Frontiers Media SA. This book was released on 2017-11-22 with total page 135 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Precision Medicine Initiative, which was instituted by President Barack Obama on January 20, 2015, highlighted the importance that advances in genomics and related “-omic” approaches have made to science and medicine, and it set the stage for their federally funded and mandated integration into the delivery of health care. Whether these advances comprise large-scale approaches, such as The Cancer Genome Atlas, which provides a modern classification of cancers based on molecular profiles, or genealogy initiatives, which seek to trace the movement of our early ancestors out of Africa, genomic technology has taken us closer to developing targeted therapies and a refined understanding of our evolutionary journey. It is against this backdrop that we summarized some of the recent advances in the field of precision medicine, or personalized medicine, as they pertain to neurosurgery. In this e-Book collection provided by Frontiers in Surgery: Neurosurgery, we present a collection of articles by leaders in the field of neurosurgery that highlight domains using a personalized approach for the treatment of patients or avenues when personalization is possible and when it will likely alter the care of patients with neurological diseases.
Book Synopsis Becoming Dr. Q by : Alfredo Quiñones-Hinojosa
Download or read book Becoming Dr. Q written by Alfredo Quiñones-Hinojosa and published by Univ of California Press. This book was released on 2011-10-01 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Today he is known as Dr. Q, an internationally renowned neurosurgeon and neuroscientist who leads cutting-edge research to cure brain cancer. But not too long ago, he was Freddy, a nineteen-year-old undocumented migrant worker toiling in the tomato fields of central California. In this gripping memoir, Alfredo Quiñones-Hinojosa tells his amazing life story—from his impoverished childhood in the tiny village of Palaco, Mexico, to his harrowing border crossing and his transformation from illegal immigrant to American citizen and gifted student at the University of California at Berkeley and at Harvard Medical School. Packed with adventure and adversity—including a few terrifying brushes with death—Becoming Dr. Q is a testament to persistence, hard work, the power of hope and imagination, and the pursuit of excellence. It’s also a story about the importance of family, of mentors, and of giving people a chance.
Book Synopsis Surviving Neurosurgery by : Nitin Agarwal
Download or read book Surviving Neurosurgery written by Nitin Agarwal and published by Springer Nature. This book was released on 2022-02-08 with total page 543 pages. Available in PDF, EPUB and Kindle. Book excerpt: Surviving Neurosurgery: Vignettes of Resilience is a practical guide to the inner workings of the lives of neurosurgeons, healthcare partners, and patients. To this end, this text serves as a first-hand documentary of the unique challenges faced as one progresses through their career. It is a snapshot in time capturing the experiences of both patients and providers. The text is divided into seven parts that run the gamut of a neurosurgeon’s career symbolic of the seven years of neurosurgical training. These narratives include, but are not limited to, residency challenges, surgical nuances, research and funding, embracing humanity, patient experiences, and overcoming hurdles along the journey. Chapters share the wisdom and experiences of over 100 authors consisting of patients, trainees, advanced practice providers, and attending neurosurgeons.
Book Synopsis Toward Precision Medicine by : National Research Council
Download or read book Toward Precision Medicine written by National Research Council and published by National Academies Press. This book was released on 2012-01-16 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt: Motivated by the explosion of molecular data on humans-particularly data associated with individual patients-and the sense that there are large, as-yet-untapped opportunities to use this data to improve health outcomes, Toward Precision Medicine explores the feasibility and need for "a new taxonomy of human disease based on molecular biology" and develops a potential framework for creating one. The book says that a new data network that integrates emerging research on the molecular makeup of diseases with clinical data on individual patients could drive the development of a more accurate classification of diseases and ultimately enhance diagnosis and treatment. The "new taxonomy" that emerges would define diseases by their underlying molecular causes and other factors in addition to their traditional physical signs and symptoms. The book adds that the new data network could also improve biomedical research by enabling scientists to access patients' information during treatment while still protecting their rights. This would allow the marriage of molecular research and clinical data at the point of care, as opposed to research information continuing to reside primarily in academia. Toward Precision Medicine notes that moving toward individualized medicine requires that researchers and health care providers have access to very large sets of health- and disease-related data linked to individual patients. These data are also critical for developing the information commons, the knowledge network of disease, and ultimately the new taxonomy.
Book Synopsis Congress of Neurological Surgeons Essential Papers in Neurosurgery by : Najib E. El Tecle
Download or read book Congress of Neurological Surgeons Essential Papers in Neurosurgery written by Najib E. El Tecle and published by Oxford University Press. This book was released on 2020-12-16 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Congress of Neurological Surgeons Essential Papers in Neurosurgery brings to the neurosurgical community a unique collection of critically appraised neurosurgical papers shedding light on some of the most impactful studies in the history of the field. Separating the signal from the noise, this text offers papers that have shaped the practice of neurosurgery, selected through a rigorous process, and commented on by editorialists to reconcile conflicting points and summarize the take-home message of each study. Each paper is reviewed by a panel of two experts who provide editorials evaluating the strengths and weaknesses of the paper as well as the impact it had on the editorialist's personal practice of neurosurgery. This book is equally suited for neurosurgery residents, practicing neurosurgeons, and anyone interested in evidence-based clinical neuroscience. The body of literature covered in this book has in many ways defined the gold standards of neurosurgical practice and is a must-know for every student of neurosurgery.
Book Synopsis Personalized Medicine and Neurosurgery by :
Download or read book Personalized Medicine and Neurosurgery written by and published by . This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Precision Medicine Initiative, which was instituted by President Barack Obama on January 20, 2015, highlighted the importance that advances in genomics and related "-omic" approaches have made to science and medicine, and it set the stage for their federally funded and mandated integration into the delivery of health care. Whether these advances comprise large-scale approaches, such as The Cancer Genome Atlas, which provides a modern classification of cancers based on molecular profiles, or genealogy initiatives, which seek to trace the movement of our early ancestors out of Africa, genomic technology has taken us closer to developing targeted therapies and a refined understanding of our evolutionary journey. It is against this backdrop that we summarized some of the recent advances in the field of precision medicine, or personalized medicine, as they pertain to neurosurgery. In this e-Book collection provided by Frontiers in Surgery: Neurosurgery, we present a collection of articles by leaders in the field of neurosurgery that highlight domains using a personalized approach for the treatment of patients or avenues when personalization is possible and when it will likely alter the care of patients with neurological diseases.
Book Synopsis Connectomic Deep Brain Stimulation by : Andreas Horn
Download or read book Connectomic Deep Brain Stimulation written by Andreas Horn and published by Academic Press. This book was released on 2021-09-10 with total page 602 pages. Available in PDF, EPUB and Kindle. Book excerpt: Connectomic Deep Brain Stimulation (DBS) covers this highly efficacious treatment option for movement disorders such as Parkinson's Disease, Essential Tremor and Dystonia. The book examines its impact on distributed brain networks that span across the human brain in parallel with modern-day neuroimaging concepts and the connectomics of the brain. It asks several questions, including which cortical areas should DBS electrodes be connected in order to generate the highest possible clinical improvement? Which connections should be avoided? Could these connectomic insights be used to better understand the mechanism of action of DBS? How can they be transferred to individual patients, and more. This book is suitable for neuroscientists, neurologists and functional surgeons studying DBS. It provides practical advice on processing strategies and theoretical background, highlighting and reviewing the current state-of-the-art in connectomic surgery. - Written to provide a "hands-on" approach for neuroscience graduate students, as well as medical personnel from the fields of neurology and neurosurgery - Includes preprocessing strategies (such as co-registration, normalization, lead localization, VTA estimation and fiber-tracking approaches) - Presents references (key articles, books and protocols) for additional detailed study - Provides data analysis boxes in each chapter to help with data interpretation
Book Synopsis A History of Neurosurgery by : Samuel H. Greenblatt
Download or read book A History of Neurosurgery written by Samuel H. Greenblatt and published by Thieme. This book was released on 1997 with total page 648 pages. Available in PDF, EPUB and Kindle. Book excerpt: A History of Neurosurgery is the first thorough book on the history of neurosurgery published since 1951. The book is organized around a specific historiographic framework that traces the advancement of the specialty. Included are chapters on ancient trepanation, Macewen's first use of the combined technologies of anesthesia, antisepsis and cortical localization in 1879 to plan and perform craniotomies, the emergence of Harvey Cushing's leadership, the evolution of modern neurosurgical techniques and technology and much more.
Book Synopsis So You Want to be a Brain Surgeon? by : Simon Eccles
Download or read book So You Want to be a Brain Surgeon? written by Simon Eccles and published by Oxford University Press, USA. This book was released on 2009 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is aimed at the trainee doctor deciding what to specialise in. It contains contributions from experts in a wide range of medical specialties offering information on the medical paths they have chosen and what it's like to work in each area.
Book Synopsis Landmark Papers in Neurosurgery by : Reuben D. Johnson
Download or read book Landmark Papers in Neurosurgery written by Reuben D. Johnson and published by . This book was released on 2014 with total page 417 pages. Available in PDF, EPUB and Kindle. Book excerpt: Evidence-based medicine is a concept that has come to the fore in the past few years. Clinicians are increasingly encouraged to practise patient management based on available evidence in the scientific literature. For example, new pharmacological therapies are only used when large randomized trials have 'proven' that a particular drug is better than existing ones. This is also the case in surgical specialties, although surgery has traditionally seen a lack of useof this information, with individual surgeon's preferences being most influential in treatment choices. However, more recently, there has been a large expansion of trials and studies aimed at providingsurgeons with information to guide their choices using firm evidence. This new edition has been revised and expanded to include new data where relevant, and also features a new chapter on pituitary surgery. Landmark Papers in Neurosurgery 2e remains a key collection of the most important trials and studies in neurosurgery, allowing the reader to rapidly extract key results, and making it essential reading for all neurosurgeons and trainees in the field.
Book Synopsis Textbook of Personalized Medicine by : Kewal K. Jain
Download or read book Textbook of Personalized Medicine written by Kewal K. Jain and published by Humana Press. This book was released on 2015-03-17 with total page 762 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in the technology used in personalized medicine and increased applications for clinical use have created a need for this expansion and revision of Kewal K. Jain’s Textbook of Personalized Medicine. As the first definitive work on this topic, this book reviews the fundamentals and development of personalized medicine and subsequent adoptions of the concepts by the biopharmaceutical industry and the medical profession. It also discusses examples of applications in key therapeutic areas, as well as ethical and regulatory issues, providing a concise and comprehensive source of reference for those involved in healthcare management, planning and politics. Algorithms are included as a guide to those involved in the management of important diseases where decision-making is involved due to the multiple choices available. Textbook of Personalized Medicine, Second Edition will serve as a convenient source of information for physicians, scientists, decision makers in the biopharmaceutical and healthcare industries and interested members of the public.
Book Synopsis Handbook of Neurosurgery, Neurology, and Spinal Medicine for Nurses and Advanced Practice Health Professionals by : Michael Wang
Download or read book Handbook of Neurosurgery, Neurology, and Spinal Medicine for Nurses and Advanced Practice Health Professionals written by Michael Wang and published by Routledge. This book was released on 2017-12-15 with total page 751 pages. Available in PDF, EPUB and Kindle. Book excerpt: This practical handbook allows nurses, advanced practice nurses, physician assistants, and allied health professionals practicing in the fields of neurosurgery, neurology, and spinal care to quickly review essentials while in the work environment. It emphasizes procedural steps and critical elements in patient management, including intensive care, the neurological examination, differential diagnoses, and pain management. Written by a multidisciplinary team of experts, the handbook is expected to become a well-worn companion and essential aid to the busy practitioner.
Book Synopsis Ambient Ionization Mass Spectrometry by : Marek Domin
Download or read book Ambient Ionization Mass Spectrometry written by Marek Domin and published by Royal Society of Chemistry. This book was released on 2014-11-25 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ambient ionization has emerged as one of the hottest and fastest growing topics in mass spectrometry enabling sample analysis with minimal sample preparation. Introducing the subject and explaining the basic concepts and terminology, this book will provide a comprehensive, unique treatise devoted to the subject. Written by acknowledged experts, there are full descriptions on how new ionization techniques work, with an overview of their strengths, weaknesses and applications. This title will bring the reader right up to date, with both applications and theory, and will be suitable as a tutorial text for those starting in the field from a variety of disciplines.
Book Synopsis Neurosurgery Oral Board Review by : Jonathan Stuart Citow
Download or read book Neurosurgery Oral Board Review written by Jonathan Stuart Citow and published by Thieme. This book was released on 2011-06-24 with total page 391 pages. Available in PDF, EPUB and Kindle. Book excerpt: Praise for the first edition:Valuable structure for academic preparation...well-organized, comprehensive outline from which to study...good last-minute warm-up --Journal of NeurosurgeryThe second edition of Neurosurgery Oral Board Review builds on the success of the bestselling first edition in helping you prepare for your oral boards in neurosurgery. Not only does the book pinpoint the key clinical information you need, but it offers practical, confidence-building tips that will help you relax and succeed on the exam.New to this expanded and fully-updated Second Edition: Expanded introduction on what to expect at the actual exam, how to utilize your time, when and how to answer the toughest questions, and the single most important area where you must demonstrate competency 45 new illustrated clinical case vignettes offer practice in differential diagnosis, work-up, treatment, and handling complications; analysis of each case is included at the end of the book A restructured table of contentsfollows the format of the exam (first hour: spine, second hour: cranial, third hour: miscellaneous) The addition of 'Helpful Hints' at the end of each chapter give you the benefit of the authors' extensive clinical experience Comprehensive yet concise, this easy-to-use review is essential for your exam preparation and for questions that arise in clinical practice. It is also an indispensable study tool and reference for all senior residents, junior neurosurgeons getting ready to take their oral boards in neurosurgery, and neurosurgeons preparing to take their re-certification exams.
Download or read book Neurosurgery written by Anne J. Moore and published by Springer Science & Business Media. This book was released on 2007-04-22 with total page 678 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides coverage of a broad range of topics in the ?eld of neurosurgery, 5 for residents and registrars in training and for recent graduates of training programs. 6 As neurosurgical training incorporates expertise from centers worldwide, there is a 7 need to have input from specialists in neurosurgery from various countries. This text 8 is a compilation by expert authors in the USA and the UK to provide information on 9 the basic knowledge and clinical management required for optimal care of neuro- 2011 surgical patients. 1 The text is an up-to-date synopsis of the ?eld of neurosurgery from American and 2 British perspectives, which covers the most common clinical conditions encountered 3 by neurosurgeons. The chapters are organized under broad topics, including inves- 4 tigative studies, perioperative care, the role of newer techniques and the management 5 of tumors, vascular and traumatic lesions. Additional topics are then covered, includ- 6 ing pediatrics, spine and peripheral nerve lesions, as well as functional neurosurgery 7 and infections. We anticipate that trainees will ?nd this information useful for certi?- 8 cation examinations and recent graduates of neurosurgical training programs can 9 utilize this text as an update of the most important neurosurgical topics.
Book Synopsis Oxford Textbook of Neurological Surgery by : Ramez Kirollos
Download or read book Oxford Textbook of Neurological Surgery written by Ramez Kirollos and published by Oxford University Press, USA. This book was released on 2019-09-05 with total page 1177 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurosurgery is a rapidly developing and technically demanding branch of surgery that requires a detailed knowledge of the basic neuro-sciences and a thorough clinical approach. The Oxford Textbook of Neurological Surgery is an up-to-date, objective and readable text that covers the full scope of neurosurgical practice. It is part of the Oxford Textbooks in Surgery series, edited by Professor Sir Peter Morris. The book is split into 20 overarching sections (Principles of Neurosurgery, Neuro-oncology of Intrinsic Tumours; Extra-axial Tumours and Skull Lesions; Cerebro-Pontine Angle Tumours; Sellar and Supra-Sellar Tumours; Posterior Fossa Tumours; Pineal tumours; Uncommon Tumours and Tumour Syndromes; Neurotrauma and Intensive Care; Vascular Neurosurgery; Principles of Spinal Surgery; Spinal Pathology; Spinal Trauma; Peripheral Nerve Surgery; Functional Neurosurgery; Epilepsy; Paediatric Neurosurgery; Neurosurgery for Cerebrospinal Fluid Disorders and Neurosurgical Infection). Each section takes a dual approach with, 'Generic Surgical Management' chapters that focus on specific clinical problems facing the neurosurgeon (e.g. sellar/supra-sellar tumour, Intradural Spina Tumours etc.) and 'Pathology-Specific' chapters (e.g. Glioma, Meningeal Tumours, Scoliosis and Spinal Deformity, Aneurysm etc.). Where appropriate, this division provides the reader with easily accessible information for both clinical problems which present in a regional fashion and specific pathologies. The generic chapters cover aspects such as operative approaches, neuroanatomy and nuances. Specifically each chapter in the book incorporates several strands. Firstly the fundamental neuroscience (anatomy, pathology, genetics etc.) that underlies the clinical practice. Secondly, a review of the requisite clinical investigations (e.g. angiography, electrodiagnostics, radiology). Thirdly, a thorough evidence based review of clinical practice. Following this a consideration of the key debates and controversies in the field with 'pro-' and 'con-' sections (e.g. minimally invasive spine surgery, microsurgical treatment of aneurysms) is provided. A summary of the key papers and clinical scales relevant to neurosurgery form the concluding part. The book is a 'one-stop' text for trainees and consultants in neurosurgery, residents, those preparing for sub-specialty exams and other professionals allied to surgery who need to gain an understanding of the field. It acts as both a point of reference to provide a focussed refresher for the experienced neurosurgeon as well as a trusted training resource.
Book Synopsis Oncology of CNS Tumors by : Jörg-Christian Tonn
Download or read book Oncology of CNS Tumors written by Jörg-Christian Tonn and published by Springer Science & Business Media. This book was released on 2010-02-03 with total page 776 pages. Available in PDF, EPUB and Kindle. Book excerpt: Knowledge about the etiology and diagnosis as well as treatment concepts of neu- oncologic diseases is rapidly growing. This turnover of knowledge makes it dif? cult for the physician engaged in the treatment to keep up to date with current therapies. This book sets out to close the gap and pursues several innovative concepts. As a comprehensive text on neuro-oncology, its chapters are interconnected, but at the same time some chapters or subdivisions are so thoroughly assembled that the whole volume gives the impression of several books combined into one. Neuropathology is treated in an extensive and clearly structured section. The int- ested reader ? nds for each tumor entity the latest well-referenced consensus rega- ing histologic and molecular pathology. Through this “book-in-the-book” concept, information on neuropathology is readily at hand in a concise form and without ov- loading the single chapters. Pediatric neuro-oncology differs in many entities from tumors in adult patients; also, certain tumors of the CNS are typically or mainly found only in the child. Therefore, pediatric neuro-oncology was granted its own, book-like section. Tumor entities that are treated differently in children and adults are included both in the pediatric neuro-oncology section and in the general section. Entities that typically occur only in the child and adolescent are found in the pediatric section in order to avoid redundancies.
