Liver Disease in Children

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Publisher : Cambridge University Press
ISBN 13 : 1108911374
Total Pages : 875 pages
Book Rating : 4.1/5 (89 download)

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Book Synopsis Liver Disease in Children by : Frederick J. Suchy

Download or read book Liver Disease in Children written by Frederick J. Suchy and published by Cambridge University Press. This book was released on 2021-03-18 with total page 875 pages. Available in PDF, EPUB and Kindle. Book excerpt: Liver disease in children is increasing in prevalence, placing a huge burden on healthcare systems and often requiring long-term management. Offering an integrative approach to the science and clinical practice of pediatric hepatology, this is the definitive reference text for improved diagnosis and treatment strategies. In the new edition of this authoritative text, chapters have been thoroughly revised in line with major advances in the field, such as recognizing the increased frequency of fatty liver disease, and how genetic testing has the potential to establish earlier diagnoses for a variety of diseases. Disorders covered include cholestasis, metabolic disorders and hepatitis, with their presentation across the spectrum of infancy, childhood and adolescence discussed. The indications and surgical aspects of liver transplant are explained and post-transplant care is described in detail. This is a valuable resource for pediatricians, hepatologists, gastroenterologists and all clinicians involved in the care of children with liver diseases.

Pediatric Liver Tumors

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3642145043
Total Pages : 234 pages
Book Rating : 4.6/5 (421 download)

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Book Synopsis Pediatric Liver Tumors by : Arthur Zimmermann

Download or read book Pediatric Liver Tumors written by Arthur Zimmermann and published by Springer Science & Business Media. This book was released on 2011-01-18 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of liver tumors in children has seen tremendous therapeutic advances over recent years. This has been achieved through a much better understanding of the biology of disease, improved diagnostic procedures, refined methods of pretreatment tumor staging, the implementation of highly efficient chemotherapy and surgery, detailed monitoring of toxicity, and careful follow-up strategies. International controlled trials have played a key role in these advances, and many leading figures in the trials are among the editors and authors of this book. Their principal goal in Hepatic Tumors in Children is to provide the reader with a complete update on this complex and rapidly evolving field. All aspects of an impressive success story are covered, disclosing how the outcome of a previously devastating disease has been so dramatically improved. This book will prove essential reading for all who are involved in the care of children with liver tumors.

Handbook of Pediatric Surgery

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Publisher : Springer Science & Business Media
ISBN 13 : 1848821328
Total Pages : 464 pages
Book Rating : 4.8/5 (488 download)

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Book Synopsis Handbook of Pediatric Surgery by : Chandrasen K. Sinha

Download or read book Handbook of Pediatric Surgery written by Chandrasen K. Sinha and published by Springer Science & Business Media. This book was released on 2010-06-25 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although pediatric surgery is a distinct and evolving specialty, it still remains an integral part of most general surgical and paediatric medical practice. Nevertheless, surgery in children does differ from adult practice in various fundamental ways, and there are key physiological and anatomical differences that constantly need underlining. Progress and improvement in outcome has also been rapid but it is sometimes difficult for practitioners to keep themselves up-to-date with the usual surgical or paediatric text books. This book will give a concise overview of all important topics and is designed to provide information in order to recognise the common surgical conditions; namely typical symptoms and signs, investigation and then treatment management. It will also provide an anatomical and physiological background to aid understanding, in addition to emphasising logical, and where possible, evidence-based practice by the use of flow charts, tables and algorithms. Authored by an international range of leading contributors, this is the first book of its kind to offer comprehensive coverage to this topic in a quick reference, pocket-book format.

Textbook of Pediatric Gastroenterology, Hepatology and Nutrition

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Author :
Publisher : Springer
ISBN 13 : 3319171690
Total Pages : 889 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Textbook of Pediatric Gastroenterology, Hepatology and Nutrition by : Stefano Guandalini

Download or read book Textbook of Pediatric Gastroenterology, Hepatology and Nutrition written by Stefano Guandalini and published by Springer. This book was released on 2015-09-30 with total page 889 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook provides a comprehensive and state-of-the-art overview of the major issues specific to the field of pediatric gastroenterology, hepatology, and nutrition. The first part of the book, Gastroenterology and Nutrition, presents in a systematic way the overall scope of issues encountered by children (newborn to teenagers) suffering from disorders of the gastrointestinal tract, pancreas and/or presenting nutritional issues. These chapters are structured in logical sections to facilitate consultation and include major topics ranging from congenital disorders to gastrointestinal problems of the newborn, infectious diseases of the gastrointestinal tract, and approach to nutritional problems in the various pediatric ages. The second part of the book, Hepatology, is articulated in a series of chapters which present a comprehensive review of congenital and acquired disorders of the biliary tract and liver. This section also includes a critical analysis of available diagnostic and therapeutic procedures and future perspectives. Written by experts in the field, Textbook of Pediatric Gastroenterology, Hepatology and Nutrition: A Comprehensive Guide to Practice constitutes a much needed, innovative resource combining updated, reliable and comprehensive information with agile consultation for a streamlined approach to the care of children with such disorders.

Tumors of the Fetus and Infant

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Publisher : Springer Science & Business Media
ISBN 13 : 0387215816
Total Pages : 435 pages
Book Rating : 4.3/5 (872 download)

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Book Synopsis Tumors of the Fetus and Infant by : Hart Jr. Isaacs

Download or read book Tumors of the Fetus and Infant written by Hart Jr. Isaacs and published by Springer Science & Business Media. This book was released on 2007-05-08 with total page 435 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past five years, remarkable advances in fetal surgery and imaging techniques such as ultrasound and "fast" MRI have occurred, resulting in increased numbers of antenatal tumor diagnoses even on "routine" prenatal examinations. Tumors of the fetus & Infant presents an up-to-date account of the clinical and pathological features of neoplastic disease and tumor-like conditions in the fetus and neonate and discusses major tumor studies and cases from throughout the world. Numerous summary tables provide superb guidance on treatment and survival rates, and over 3,000 references direct the reader to the best current and classic sources.

Tumors and Tumor-Like Lesions of the Hepatobiliary Tract

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Author :
Publisher : Springer
ISBN 13 : 9783319269559
Total Pages : 3517 pages
Book Rating : 4.2/5 (695 download)

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Book Synopsis Tumors and Tumor-Like Lesions of the Hepatobiliary Tract by : Arthur Zimmermann

Download or read book Tumors and Tumor-Like Lesions of the Hepatobiliary Tract written by Arthur Zimmermann and published by Springer. This book was released on 2016-11-02 with total page 3517 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers all liver tumors and lesions that clinically and radiologically mimic liver tumors. It provides readers with a comprehensive overview of this complex and rapidly evolving field. All aspects of surgical pathology are addressed, supplemented by detailed presentations of the lesions’ cell-biologic and molecular features. In addition, the methods employed for diagnosis and diagnostic algorithms are discussed. It appeals to pathologists and hepatologists and serves as an invaluable aid to diagnosis.The field of liver tumors and tumor-like lesions in adults and children has experienced tremendous advances in recent years. Specifically, the recognition of novel entities, deepened insights into known tumors, and refinement of classifications have necessitated continual updates and reappraisals. In addition, previous understanding of hepatic carcinogenesis and tumor progression has been transformed by the very rapid evolution of our understanding of cell biology, genomics, signaling pathways, cell interactions, and mechanisms of invasion and spread of hepatic tumor cells. These general pathology issues must be combined with surgical pathology if a comprehensive understanding of liver tumor pathology is to be achieved.

Mulliken and Young's Vascular Anomalies

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Publisher : Oxford University Press
ISBN 13 : 0199722544
Total Pages : 1139 pages
Book Rating : 4.1/5 (997 download)

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Book Synopsis Mulliken and Young's Vascular Anomalies by : John B. Mulliken

Download or read book Mulliken and Young's Vascular Anomalies written by John B. Mulliken and published by Oxford University Press. This book was released on 2013-05-01 with total page 1139 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of vascular anomalies has grown rapidly in last 25 years. Molecular genetics has led to discovery of genes that cause vascular anomalies. Interventional radiology has become a major contributor to accurate diagnosis and management of previously untreatable disorders. New pharmacologic therapies are under investigation and surgical protocols have been established. Vascular Anomalies: Hemangiomas and Malformations is a comprehensive and interdisciplinary textbook ideal for dermatologists, interventional radiologists, surgical specialists, ophthalmologists, pathologists, geneticists, pediatricians, hematologic-oncologists, and vascular biologists. With a central motif of the biologic dichotomy of vascular tumors and vascular malformations, this book is organized into chapters which address clinical presentation, diagnostic imaging, molecular genetics, pathogenesis, histopathology, and management of vascular anomalies. Generous, full-color images compliment this extensive volume written by three colleagues and their teammates from Children's Hospital Boston and Harvard Medical School, with leading specialists from other centers.

Liver MRI

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Author :
Publisher : Springer
ISBN 13 : 331906004X
Total Pages : 357 pages
Book Rating : 4.3/5 (19 download)

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Book Synopsis Liver MRI by : Shahid M. Hussain

Download or read book Liver MRI written by Shahid M. Hussain and published by Springer. This book was released on 2014-12-07 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of this very successful book provides a practical approach to liver MRI, with coverage of the most up-to-date MR imaging sequences, normal and variant anatomy and diverse pathologic conditions. It features computer-generated drawings relating clinical concepts to the MRI findings, 2D and 3D reconstructions, systematic (differential) diagnostic information and descriptions of patient management options. MRI findings are correlated to ultrasound, computed tomography, nuclear medicine exams, laboratory findings and histopathology when appropriate. New information is presented on a wide range of topics and more than 50 extra figure pages are included. This book will greatly benefit all professionals interested and involved in imaging, diagnosis and treatment of focal and diffuse liver lesions, including radiologists, gastroenterologists, hepatologists, surgeons, pathologists, MR physicists, radiology and other residents, MR technologists and medical students.p>

Hepatocellular Carcinoma

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Publisher : Springer Science & Business Media
ISBN 13 : 160327376X
Total Pages : 752 pages
Book Rating : 4.6/5 (32 download)

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Book Synopsis Hepatocellular Carcinoma by : Brian I. Carr

Download or read book Hepatocellular Carcinoma written by Brian I. Carr and published by Springer Science & Business Media. This book was released on 2009-10-03 with total page 752 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hepatocellular cancer is the fifth most common cancer, with 600,000 new cases reported each year worldwide. Additionally, exciting changes in the science of HCC in the last four years have turned the practice of diagnosing and treating the disease upside down. In Hepatocellular Carcinoma: Diagnosis and Treatment, Second Edition, the leading experts in the field of HCC thoroughly update and expand upon the critically acclaimed first edition with all the latest developments in the diagnosis and treatment of primary liver cancer. The book details for physicians the diagnostic and therapeutic decision making process for dealing with such problems as incidental tumors in the liver transplant, the role of neo-adjuvant chemotherapy, intra-arterial vs intravenous therapy, the uses of embolization, and the significance of portal vein thrombus. New chapters discuss the introduction into clinical practice of cell cycle growth inhibitors, an expanded knowledge of Genomics and Proteomics, and novel ways of delivering intra-hepatic chemotherapy. This cutting-edge text is a vital resource and must have for today’s hepatologists and medical and surgical oncologists.

Malignant Liver Tumors

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1444356399
Total Pages : 1039 pages
Book Rating : 4.4/5 (443 download)

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Book Synopsis Malignant Liver Tumors by : Pierre-Alain Clavien

Download or read book Malignant Liver Tumors written by Pierre-Alain Clavien and published by John Wiley & Sons. This book was released on 2011-09-23 with total page 1039 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive and critical review of current and established treatment modalities for malignant liver tumors is designed to help you sort through the proliferation of competitive approaches and choose the best treatment options for your patient. Dr. Clavien and his contributors consider all the options – radiological, surgical, pharmaceutical, and emerging/novel therapies – and help you find the best single or combined therapy. Building on the success of the previous edition, this extremely thorough revision: features a new section on Guidelines for Liver Tumors, where you will find specific strategies for treating common liver malignancies; the guidelines were prepared by the Associate Editors and take into account national and international society guidelines reflects actual practice by taking a multidisciplinary approach, with contributions from international experts who have extensive experience with this patient population achieves comprehensive and balanced coverage by having each chapter reviewed by the Editor, Deputy Editor, two Associate Editors, and at least one external reviewer includes 16 new chapters that cover liver anatomy, histologic changes in the liver, epidemiology and natural history of HCC, CCC and colorectal liver metastases, strategies of liver resection, and economic aspects as well as novel therapies facilitates the kind of daily interaction among hepatologists, hepatic surgeons, medical oncologists, radiotherapists, and interventional radiologists that is essential when treating patients with complex liver malignancies In 44 chapters organized into six major sections, the book covers the full range of liver tumors. The perfect blend of evidence and experience, Malignant Liver Tumors: Current and Emerging Therapies, 3rd Edition, illuminates the path to better patient care.

Tumors of the Liver and Intrahepatic Bile Ducts

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Author :
Publisher : American Registry of Pathology
ISBN 13 :
Total Pages : 372 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Tumors of the Liver and Intrahepatic Bile Ducts by : Kamal G. Ishak

Download or read book Tumors of the Liver and Intrahepatic Bile Ducts written by Kamal G. Ishak and published by American Registry of Pathology. This book was released on 2001 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Pediatric Germ Cell Tumors

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Publisher : Springer Science & Business Media
ISBN 13 : 3642389716
Total Pages : 144 pages
Book Rating : 4.6/5 (423 download)

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Book Synopsis Pediatric Germ Cell Tumors by : A. Lindsay Frazier

Download or read book Pediatric Germ Cell Tumors written by A. Lindsay Frazier and published by Springer Science & Business Media. This book was released on 2013-10-28 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: Germ cell tumors are relatively rare compared with other malignancies, and compilations of knowledge that encompass the entire spectrum of the disease are lacking. This textbook, written by the foremost authorities in the field, rectifies the situation by discussing in depth a broad range of topics, including biology, epidemiology, pathology, treatment, and late effects. Bearing in mind that germ cell tumors are most prevalent in the adolescent and young adult age group, causes of disease and treatment approaches in pediatric and adult patients are compared and contrasted. By spanning the entire life course, from prenatal origins of disease through to treatment in adults and late effects of treatment, the editors have produced a book that will be of interest to both pediatric and adult oncologists.

Diseases of the Liver and Biliary System in Children

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Publisher : John Wiley & Sons
ISBN 13 : 1405140275
Total Pages : 512 pages
Book Rating : 4.4/5 (51 download)

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Book Synopsis Diseases of the Liver and Biliary System in Children by : Deirdre A. Kelly

Download or read book Diseases of the Liver and Biliary System in Children written by Deirdre A. Kelly and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: An extremely practical text, this new edition of Diseases of the Liver and Biliary System in Children covers the essentials of paediatric hepatology. The range of material is wide and has been revised and updated to include the latest advances. Many helpful algorithms and tables are included and the references at the end of each chapter have been carefully selected so as to provide the most up-to-date information available. A concluding section comprising some 100 carefully annotated plates, completes this text. Containing the contributions of 23 internationally acclaimed authorities, active both clinically and in research, the book provides an essential guide to the diagnosis and management of paediatric liver diseases, both common and uncommon for all those involved in the care of the child with liver disease. Diseases of the Liver and Biliary System in Children has become THE REFERENCE of choice for the paediatric gastroenterologist, hepatologist and surgeon.

Pearls and Tricks in Pediatric Surgery

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Author :
Publisher : Springer Nature
ISBN 13 : 3030510670
Total Pages : 522 pages
Book Rating : 4.0/5 (35 download)

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Book Synopsis Pearls and Tricks in Pediatric Surgery by : Martin Lacher

Download or read book Pearls and Tricks in Pediatric Surgery written by Martin Lacher and published by Springer Nature. This book was released on 2020-10-29 with total page 522 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing core information on pediatric surgery, this book serves as a supplement to standard pediatric surgical textbooks. It offers pearls of wisdom that will help those who participate in pediatric surgical care, as well as to provide state-of-the-art insights based on physiological principles, literature reviews, and clinical experience. This book is an ideal tool to help readers prepare for questions they will be asked on ward rounds, in the OR, or in oral exams. The depth of exploration is intended for medical students, residents in pediatrics and pediatric surgery, pediatric surgical trainees, pediatric nurse practitioners, primary care pediatricians, and family practitioners.

Essentials of Surgical Pediatric Pathology

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Author :
Publisher : Cambridge University Press
ISBN 13 : 1316124150
Total Pages : 1225 pages
Book Rating : 4.3/5 (161 download)

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Book Synopsis Essentials of Surgical Pediatric Pathology by : Marta C. Cohen

Download or read book Essentials of Surgical Pediatric Pathology written by Marta C. Cohen and published by Cambridge University Press. This book was released on 2015-02-05 with total page 1225 pages. Available in PDF, EPUB and Kindle. Book excerpt: Essentials of Surgical Pediatric Pathology is a clear and practical yet comprehensive guide for trainee pediatric pathologists and non-pediatric pathologists. Each chapter corresponds to one of the main subspecialties, such as dermatopathology, head and neck pathology, and system pathology. Practical guidance is given on handling pediatric specimens and the authors highlight the ways in which common conditions present differently in adults and children. Other chapters cover conditions typical of childhood, including soft tissue tumors and blue round cell tumors. The chapters begin with a brief clinical presentation, followed by a clear macroscopical and histological description of the principal pathologies seen in children. Up-to-date genetic and immunohistochemical information is provided, and the book includes hundreds of high-quality color images. Written and edited by leading international experts in the field, this is an essential resource for trainee pediatric pathologists, as well as general pathologists who may encounter pediatric cases.

Clinical and Molecular Insights Into Primary Pediatric Liver Cancer

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Author :
Publisher :
ISBN 13 : 9789090298580
Total Pages : 0 pages
Book Rating : 4.2/5 (985 download)

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Book Synopsis Clinical and Molecular Insights Into Primary Pediatric Liver Cancer by : Víola Benedicte Weeda

Download or read book Clinical and Molecular Insights Into Primary Pediatric Liver Cancer written by Víola Benedicte Weeda and published by . This book was released on 2016 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thesis aims to give insight into the clinical status quo of primary pediatric liver tumors and investigate signaling pathways that may be of importance for liver tumorigenesis. The most recent series of the International Childhood Liver Tumors Strategy Group (SIOPEL) of hepatocellular carcinoma (HCC) and its distinct variant fibrolamellar hepatocellular carcinoma (FL-HCC) are discussed. For both tumors, complete resection is at present the only curative option. FL-HCC does not have a better prognosis than HCC. A potential role for the Delta-Notch signaling pathway in hepatoblastoma is explored and although this cannot be detected, interestingly, tissue-specific Notch 2 deletion is found to lead to bile duct agenesis. The role of the DCUN1D1-5 proteins and the neddylation and ubiquitination signaling pathways in hepatotumorigenesis was studied. The paralogues DCUN1D3 and DCUN1D5 were characterized; DCUN1D3 is shown to function as a tumor suppressor, whereas DCUN1D5 functions as an oncogene exhibiting an oncogene addiction phenotype. DCUN1D paralogue expression is found to correlate with function in liver cancer tissue and increased function correlates with low LD50 and IC50 of the neddylation inhibiting compound MLN4924. The oncogene addiction phenotype observed for several paralogues may thus be exploited to select liver tumors for treatment with such a drug..

Pediatric Hepatology and Liver Transplantation

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Author :
Publisher : Springer
ISBN 13 : 3319964003
Total Pages : 829 pages
Book Rating : 4.3/5 (199 download)

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Book Synopsis Pediatric Hepatology and Liver Transplantation by : Lorenzo D'Antiga

Download or read book Pediatric Hepatology and Liver Transplantation written by Lorenzo D'Antiga and published by Springer. This book was released on 2019-04-29 with total page 829 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the first to provide balanced examination of both pediatric liver disease and liver transplantation – two topics that are inherently related, given that most chronic liver disorders eventually require organ replacement. The different forms of liver disease encountered in the pediatric age group are first discussed in a series of disease-specific chapters that have a reader-friendly, uniform structure covering pathophysiology, diagnostic and treatment algorithms, clinical cases, and transition to adult care. Key topics in the field of liver transplantation are then addressed. Examples include indications and contraindications, surgical techniques and complications, immunosuppression, in pediatric liver transplantation, acute and chronic rejection and allograft dysfunction, and CMV and EBV infection in transplant recipients, long-term graft injury and tolerance. A section on pediatric hepatology across the world includes chapters presenting the features and management of pediatric liver disease in South-America, Africa and Asia. A closing section considers what the future holds for pediatric liver disease and its management, including novel genetic testing, cell therapy and gene therapy. Pediatric Hepatology and Liver Transplantation will be of value for a range of practitioners, from residents making their first approach to pediatric liver disease through to specialists working in transplantation centers.