Pathogenesis Of Hemodynamic Changes During Raised Intracranial Pressure

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Pathogenesis of Hemodynamic Changes During Raised Intracranial Pressure

Author : Johannes Jacobus Louisa van Loon
Publisher : Leuven University Press
ISBN 13 : 9789058673084
Total Pages : 162 pages
Book Rating : 4.6/5 (73 download)

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Book Synopsis Pathogenesis of Hemodynamic Changes During Raised Intracranial Pressure by : Johannes Jacobus Louisa van Loon

Download or read book Pathogenesis of Hemodynamic Changes During Raised Intracranial Pressure written by Johannes Jacobus Louisa van Loon and published by Leuven University Press. This book was released on 2003-09 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Cerebral cardiovascular control: anatomical and physiological aspects, Catecholamine response to a gradual increase of ICP, Course of ICP changes in two models of progressive intracranial hypertension, Pathogenetic aspects of the hemodynamic changes during raised intracranial pressure, Summary and Conclusions."

Translational Research in Traumatic Brain Injury

Author : Daniel Laskowitz
Publisher : CRC Press
ISBN 13 : 1498766579
Total Pages : 388 pages
Book Rating : 4.4/5 (987 download)

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Book Synopsis Translational Research in Traumatic Brain Injury by : Daniel Laskowitz

Download or read book Translational Research in Traumatic Brain Injury written by Daniel Laskowitz and published by CRC Press. This book was released on 2016-04-21 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the developme

Neurotrauma

Author : Raj K. Narayan
Publisher : McGraw-Hill
ISBN 13 : 9780070456624
Total Pages : 1558 pages
Book Rating : 4.4/5 (566 download)

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Book Synopsis Neurotrauma by : Raj K. Narayan

Download or read book Neurotrauma written by Raj K. Narayan and published by McGraw-Hill. This book was released on 1996 with total page 1558 pages. Available in PDF, EPUB and Kindle. Book excerpt: This reference is a comprehensive work in the field of neurotrauma and critical care. It incorporates the fields of head injury, spinal injury and basic neurotrauma research into one source. The major emphasis is on the treatment of patients with head and spinal cord injury, including the management of all other problems that bear upon the care of these patients.

The Cerebral Circulation

Author : Marilyn J. Cipolla
Publisher : Biota Publishing
ISBN 13 : 1615047239
Total Pages : 82 pages
Book Rating : 4.6/5 (15 download)

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Book Synopsis The Cerebral Circulation by : Marilyn J. Cipolla

Download or read book The Cerebral Circulation written by Marilyn J. Cipolla and published by Biota Publishing. This book was released on 2016-07-28 with total page 82 pages. Available in PDF, EPUB and Kindle. Book excerpt: This e-book will review special features of the cerebral circulation and how they contribute to the physiology of the brain. It describes structural and functional properties of the cerebral circulation that are unique to the brain, an organ with high metabolic demands and the need for tight water and ion homeostasis. Autoregulation is pronounced in the brain, with myogenic, metabolic and neurogenic mechanisms contributing to maintain relatively constant blood flow during both increases and decreases in pressure. In addition, unlike peripheral organs where the majority of vascular resistance resides in small arteries and arterioles, large extracranial and intracranial arteries contribute significantly to vascular resistance in the brain. The prominent role of large arteries in cerebrovascular resistance helps maintain blood flow and protect downstream vessels during changes in perfusion pressure. The cerebral endothelium is also unique in that its barrier properties are in some way more like epithelium than endothelium in the periphery. The cerebral endothelium, known as the blood-brain barrier, has specialized tight junctions that do not allow ions to pass freely and has very low hydraulic conductivity and transcellular transport. This special configuration modifies Starling's forces in the brain microcirculation such that ions retained in the vascular lumen oppose water movement due to hydrostatic pressure. Tight water regulation is necessary in the brain because it has limited capacity for expansion within the skull. Increased intracranial pressure due to vasogenic edema can cause severe neurologic complications and death.

Transcranial Doppler Sonography

Author : Rune Aaslid
Publisher : Springer Science & Business Media
ISBN 13 : 3709188644
Total Pages : 187 pages
Book Rating : 4.7/5 (91 download)

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Book Synopsis Transcranial Doppler Sonography by : Rune Aaslid

Download or read book Transcranial Doppler Sonography written by Rune Aaslid and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 187 pages. Available in PDF, EPUB and Kindle. Book excerpt: Every few years a dissertation comes to the area of clinical application of medical technology which carries us forward as on a magic carpet into new regions of understanding and patient care. This book is such a magic carpet. It brings together, in a clear and incisive fashion, important hemodynamic principles with a simple noninvasive method of application to a part of the cerebral vasculature which has been relatively inaccessible. To the lucky and perceptive person who reads this book, a feeling of excitement and hope for progress is engendered. The diligent application of the potentials of transcranial Doppler ultrasound brings new power to our efforts in understanding the cerebral circulation and the causes, treatment and prevention of cerebrovascular disorders. Merrill P. Spencer, M. D. Director Institute of Applied Physiology and Medicine Seattle, Wash. , July 1986 Acknowledgements I am greatly indebted to Prof. He1ge Nornes, Oslo, who introduced me to the fascinating study of cerebral hemodynamics in the early 1970's and since then continually encouraged my interest in this field. It was through his pioneering work on the cerebral circulation-using peroperative electromagnetic flowmetry and Doppler techniques-that the basis was laid for the noninvasive trans cranial approach to the circle of Willis described in this book. I also gratefully acknowledge the stimulating case discussions with Prof. Peter Huber, Berne, at the very early introduction of trans cranial Doppler, the inspiring exchange of ideas with Dr. Merrill P.

Neurological and Neurosurgical Intensive Care

Author : Allan H. Ropper
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 9780781731966
Total Pages : 408 pages
Book Rating : 4.7/5 (319 download)

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Book Synopsis Neurological and Neurosurgical Intensive Care by : Allan H. Ropper

Download or read book Neurological and Neurosurgical Intensive Care written by Allan H. Ropper and published by Lippincott Williams & Wilkins. This book was released on 2004 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: The standard text and reference on neurological and neurosurgical intensive care is now in its Fourth Edition–thoroughly revised to incorporate the latest therapeutic advances and insights from the most recent clinical trials. A team of distinguished neuro-intensivists offers practical, state-of-the-art guidelines for managing the wide range of problems arising in postoperative neurosurgical care and care of patients with acute neurological diseases. This edition focuses sharply on the details of therapeutics. The authors, from leading neuro-intensive care units, have written the book collectively, giving it more cohesiveness and more of an authoritative consensus voice than previous multiauthored editions.

Management of Subarachnoid Hemorrhage

Author : Adel E. Ahmed Ganaw
Publisher : Springer Nature
ISBN 13 : 3030813339
Total Pages : 227 pages
Book Rating : 4.0/5 (38 download)

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Book Synopsis Management of Subarachnoid Hemorrhage by : Adel E. Ahmed Ganaw

Download or read book Management of Subarachnoid Hemorrhage written by Adel E. Ahmed Ganaw and published by Springer Nature. This book was released on 2021-11-26 with total page 227 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on subarachnoid hemorrhage (SAH), describing in detail the neurophysiology, anatomy, epidemiology, grading, anesthesia management, coiling and interventional treatment of this dangerous disease. Written by leading international experts, it highlights the state-of-the-art techniques for the diagnosis and treatment (non-surgical and surgical) of SAH and the clinical variations. It also examines the reliability of the new techniques versus the standard clinical methods to predict problems related to SAH and its recent diagnosis and management. The book starts with a brief discussion of the epidemiology of SAH, cerebral circulation, anatomy of brain blood vessels and neurophysiology related to this fatal disease. Then, in the following chapters it covers grading of subarachnoid hemorrhage, anesthesia management of SAH, treatment, subarachnoid hemorrhage coiling and radiological intervention. Lastly, it explores surgical treatment of intracranial aneurysms in more detail, and addresses complications, critical care management and headache in SAH, traumatic SAH and prognosis. Featuring numerous images, tables, schema, illustrations and videos, the book is intended for junior and senior anesthesiologists, neuroscientists, intervention radiologists, intensivists and neurosurgeons.

Critical Care of the Stroke Patient

Author : Stefan Schwab
Publisher : Cambridge University Press
ISBN 13 : 1139991558
Total Pages : 579 pages
Book Rating : 4.1/5 (399 download)

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Book Synopsis Critical Care of the Stroke Patient by : Stefan Schwab

Download or read book Critical Care of the Stroke Patient written by Stefan Schwab and published by Cambridge University Press. This book was released on 2014-06-05 with total page 579 pages. Available in PDF, EPUB and Kindle. Book excerpt: New and groundbreaking therapeutic options for the critical care of patients with cerebrovascular disease have improved patient management, minimized morbidity, reduced in-patient care, improved quality of life, and had a positive economic impact on health service provision. This volume integrates these approaches and suggests the best therapy option for all cerebrovascular conditions. The early chapters of the book focus on monitoring techniques and interventions. Subsequent sections address the critical care of a wide range of cerebrovascular diseases: ischemic stroke, intracranial hemorrhage, subarachnoid hemorrhage, arteriovenous malformations, cerebral venous thrombosis and traumatic injury. The editors and authors are internationally recognized experts in their field, and the text is supplemented by tables and illustrations to demonstrate important clinical findings. This book will meet the needs of stroke physicians, neurologists, neurosurgeons, neurointensivists and interventional neuroradiologists seeking to maximize positive outcomes for their patients.

Intracranial Pressure and Brain Monitoring XIII

Author : Geoffrey Manley
Publisher : Springer Science & Business Media
ISBN 13 : 3211855785
Total Pages : 411 pages
Book Rating : 4.2/5 (118 download)

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Book Synopsis Intracranial Pressure and Brain Monitoring XIII by : Geoffrey Manley

Download or read book Intracranial Pressure and Brain Monitoring XIII written by Geoffrey Manley and published by Springer Science & Business Media. This book was released on 2009-05-06 with total page 411 pages. Available in PDF, EPUB and Kindle. Book excerpt: 86 short papers originating from the 13th International Symposium on Intracranial Pressure and Brain Monitoring held in July 2007 in San Francisco present experimental as well as clinical research data on invasive and non-invasive intracranial pressure and brain biochemistry monitoring. The papers have undergone a peer-reviewing and are organized in eight sections: brain injury: ICP management and cerebral physiology; hydrocephalus and cerebrospinal fluid dynamics; advanced neuromonitoring; biomedical informatics; imaging; ICP: brain compliance, biophysics, and biomechanics; stroke, subarachnoid hemorrhage, and intracerebral hematoma; and experimental studies and models. The papers address the increasing use of decompressive craniectomy for the treatment of brain edema as well after brain injury and the rapidly expanding field of advanced neuromonitoring and neuroimaging.

Monitoring in Neurocritical Care

Author : Peter D. Le Roux
Publisher : Saunders
ISBN 13 : 9781437701678
Total Pages : 0 pages
Book Rating : 4.7/5 (16 download)

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Book Synopsis Monitoring in Neurocritical Care by : Peter D. Le Roux

Download or read book Monitoring in Neurocritical Care written by Peter D. Le Roux and published by Saunders. This book was released on 2013 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ideal for neurosurgeons, neurologists, neuroanesthesiologists, and intensivists, Monitoring in Neurocritical Care helps you use the latest technology to more successfully detect deteriorations in neurological status in the ICU. This neurosurgery reference offers in-depth coverage of state-of-the-art management strategies and techniques so you can effectively monitor your patients and ensure the best outcomes. Understand the scientific basis and rationale of particular monitoring techniques and how they can be used to assess neuro-ICU patients. Make optimal use of the most advanced technology, including transcranial Doppler sonography, transcranial color-coded sonography, measurements of jugular venous oxygen saturation, near-infrared spectroscopy, brain electrical monitoring techniques, and intracerebral microdialysis and techniques based on imaging. Apply multimodal monitoring for a more accurate view of brain function, and utilize the latest computer systems to integrate data at the bedside. Access practical information on basic principles, such as quality assurance, ethics, and ICU design. Seamlessly search the full text of Monitoring in Neurocritical Care online at www.expertconsult.com.

Trauma Induced Coagulopathy

Author : Hunter B. Moore
Publisher : Springer Nature
ISBN 13 : 3030536068
Total Pages : 802 pages
Book Rating : 4.0/5 (35 download)

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Book Synopsis Trauma Induced Coagulopathy by : Hunter B. Moore

Download or read book Trauma Induced Coagulopathy written by Hunter B. Moore and published by Springer Nature. This book was released on 2020-10-12 with total page 802 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first edition of this publication was aimed at defining the current concepts of trauma induced coagulopathy by critically analyzing the most up-to-date studies from a clinical and basic science perspective. It served as a reference source for any clinician interested in reviewing the pathophysiology, diagnosis, and management of the coagulopathic trauma patient, and the data that supports it. By meticulously describing the methodology of most traditional as well as state of the art coagulation assays the reader is provided with a full understanding of the tests that are used to study trauma induced coagulopathy. With the growing interest in understanding and managing coagulation in trauma, this second edition has been expanded to 46 chapters from its original 35 to incorporate the massive global efforts in understanding, diagnosing, and treating trauma induced coagulopathy. The evolving use of blood products as well as recently introduced hemostatic medications is reviewed in detail. The text provides therapeutic strategies to treat specific coagulation abnormalities following severe injury, which goes beyond the first edition that largely was based on describing the mechanisms causing coagulation abnormalities. Trauma Induced Coagulopathy 2nd Edition is a valuable reference to clinicians that are faced with specific clinical challenges when managing coagulopathy.

Right Ventricular Contractile Function

Author : H. Alex Leather
Publisher : Leuven University Press
ISBN 13 : 9789058674531
Total Pages : 192 pages
Book Rating : 4.6/5 (745 download)

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Book Synopsis Right Ventricular Contractile Function by : H. Alex Leather

Download or read book Right Ventricular Contractile Function written by H. Alex Leather and published by Leuven University Press. This book was released on 2005 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a Ph.D. dissertation. Introduction, The limitations of preload-adjusted maximal power as an index of right ventricular contractility, Preload-adjusted maximal power of the right ventricle: contribution of the intercept of the end-systolic P-V relation (Vd), Regional indices of global right ventricular contractility: longitudinal versus circumferential axis, and isovolumic versus ejection phase indicies, Acute pulmonary hypertension causes depression of left ventricular contractility and relaxation, Effects of vasopressin on right ventricular function in an experimental model of acute pulmonary hypertension, Effects of levosimendan on right ventricular function and ventriculovascular coupling in open chest pigs, Discussion.

Molecular Modes of Action of 1[alpha], 25-dihydroxyvitamin D3 and Analogs

Author : Guy Eelen
Publisher : Leuven University Press
ISBN 13 : 9789058674753
Total Pages : 206 pages
Book Rating : 4.6/5 (747 download)

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Book Synopsis Molecular Modes of Action of 1[alpha], 25-dihydroxyvitamin D3 and Analogs by : Guy Eelen

Download or read book Molecular Modes of Action of 1[alpha], 25-dihydroxyvitamin D3 and Analogs written by Guy Eelen and published by Leuven University Press. This book was released on 2005 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Neonatal Analgesia

Author : Karel Allegaert
Publisher : Leuven University Press
ISBN 13 : 9789058675057
Total Pages : 168 pages
Book Rating : 4.6/5 (75 download)

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Book Synopsis Neonatal Analgesia by : Karel Allegaert

Download or read book Neonatal Analgesia written by Karel Allegaert and published by Leuven University Press. This book was released on 2005 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Protein Phosphatase-1 Binding Motifs

Author : Paulina Wakula
Publisher : Leuven University Press
ISBN 13 : 9789058675217
Total Pages : 138 pages
Book Rating : 4.6/5 (752 download)

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Book Synopsis Protein Phosphatase-1 Binding Motifs by : Paulina Wakula

Download or read book Protein Phosphatase-1 Binding Motifs written by Paulina Wakula and published by Leuven University Press. This book was released on 2006 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt:

A Rational Approach to Pedal Cyclist Head Protection

Author : Bart Depreitere
Publisher : Leuven University Press
ISBN 13 : 9789058673756
Total Pages : 168 pages
Book Rating : 4.6/5 (737 download)

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Book Synopsis A Rational Approach to Pedal Cyclist Head Protection by : Bart Depreitere

Download or read book A Rational Approach to Pedal Cyclist Head Protection written by Bart Depreitere and published by Leuven University Press. This book was released on 2004 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This is a Ph.D. dissertation. In western countries, head injury is a major cause of morbidity and mortality. While traumatic injuries are the leading cause of death under the age of 45 years, up to half of the trauma deaths and the majority of cases of permanent disability are directly related to a sustained head injury. In the U.S. an estimated 1.5 million people sustain head injury each year. As a result of these injuries, 50,000 people die, 230,000 people are hospitalized and survive and an estimated 80,000 - 90,000 people experience long-term disability. Contents include: Introduction, Aims of the Study, Analysis of Bicycle Accidents and the Resultant Head Injuries in a Study of 86 cases, Investigations on the Mechanics of Skull and Brain Injuries, Investigation of Bicycle Safety Helmet Performance in Impact Testing, General Discussion and Perspectives."

Multiple Approaches to Inhibit Restenosis After Percutaneous Coronary Interventions

Author : Xiaoshun Liu
Publisher : Leuven University Press
ISBN 13 : 9789058674432
Total Pages : 190 pages
Book Rating : 4.6/5 (744 download)

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Book Synopsis Multiple Approaches to Inhibit Restenosis After Percutaneous Coronary Interventions by : Xiaoshun Liu

Download or read book Multiple Approaches to Inhibit Restenosis After Percutaneous Coronary Interventions written by Xiaoshun Liu and published by Leuven University Press. This book was released on 2004 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a Ph.D. dissertation. Restenosis occurs in 10-50% of patients after PCI, thus remaining a major challenge. Restenosis after PCI is a complex, multifactorial, overlapping wound healing process involving a cascade of cellular and molecular events including platelet activation, inflammatory cell infiltration, smooth muscle cell proliferation, migration and extracellular matrix production. Recent evidence shows that inflammation, matrix metalloproteinases and free oxygen radicals all play a critical role in the restenosis process. Different approaches to prevent restenosis after PCI were studied in this work. Restenosis has been remarkably reduced in the last decade with the introduction of stents. Stents have been optimized regarding their mechanical features, allowing for scaffolding of the plaque and producing an optimal coronary lumen at the end of the procedure. By their metallic nature however, they cause prolonged and chronic inflammation in the vessel wall. Therefore, the long term efficacy remains a concern. In the first study, the author evaluated the long-term follow-up of patients that underwent bare metal stent implantation. The long-term efficacy of this stent was established, and the major adverse cardiac events (MACE) during the long-term follow-up were mainly caused by progression of lesions in other vessels. This study confirmed that implantation of a bare metal stent in an effective treatment modality of atherosclerotic coronary disease. However, in-stent restenosis still results in a failure of this treatment in about 30% of the patients, mostly occurring within the first 6 months.