Pathogen Genomics

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Pathogen Genomics

Author : Karen Joy Shaw
Publisher : Springer Science & Business Media
ISBN 13 : 1592591728
Total Pages : 513 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Pathogen Genomics by : Karen Joy Shaw

Download or read book Pathogen Genomics written by Karen Joy Shaw and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 513 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leading infectious disease researchers and pharmaceutical scientists comprehensively review the latest genomic technologies and their application to the prevention, diagnosis, and treatment. The authors' cross-disciplinary approach, with expertise acquired from studying disease-causing viruses, bacteria, fungi, and protozoa, reveals how sequence information from diverse pathogens has uncovered novel targets for drug discovery, antigenic determinants for vaccine development, as well as diagnostic tools. The authors also discuss the application of DNA micoarrays and the impact of genome sequencing comparisons on the discovery and choices of novel drug targets. The result is a better understanding how genomic information can reveal the fundamentals of microbial pathogenesis and how organisms interact with their host environment.

Pathogen Genomics: Empowering Infectious Disease Surveillance and Outbreak Investigations

Author : Marc Jean Struelens
Publisher : Frontiers Media SA
ISBN 13 : 2889638227
Total Pages : 160 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Pathogen Genomics: Empowering Infectious Disease Surveillance and Outbreak Investigations by : Marc Jean Struelens

Download or read book Pathogen Genomics: Empowering Infectious Disease Surveillance and Outbreak Investigations written by Marc Jean Struelens and published by Frontiers Media SA. This book was released on 2020-07-03 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Applied Genomics of Foodborne Pathogens

Author : Xiangyu Deng
Publisher : Springer
ISBN 13 : 3319437518
Total Pages : 213 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Applied Genomics of Foodborne Pathogens by : Xiangyu Deng

Download or read book Applied Genomics of Foodborne Pathogens written by Xiangyu Deng and published by Springer. This book was released on 2017-01-23 with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a timely and thorough snapshot into the emerging and fast evolving area of applied genomics of foodborne pathogens. Driven by the drastic advance of whole genome shot gun sequencing (WGS) technologies, genomics applications are becoming increasingly valuable and even essential in studying, surveying and controlling foodborne microbial pathogens. The vast opportunities brought by this trend are often at odds with the lack of bioinformatics know-how among food safety and public health professionals, since such expertise is not part of a typical food microbiology curriculum and skill set. Further complicating the challenge is the large and ever evolving body of bioinformatics tools that can obfuscate newcomers to this area. Although reviews, tutorials and books are not in short supply in the fields of bioinformatics and genomics, until now there has not been a comprehensive and customized source of information designed for and accessible to microbiologists interested in applying cutting-edge genomics in food safety and public health research. This book fills this void with a well-selected collection of topics, case studies, and bioinformatics tools contributed by experts at the forefront of foodborne pathogen genomics research.

Seeking Security

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309093058
Total Pages : 88 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Seeking Security by : National Research Council

Download or read book Seeking Security written by National Research Council and published by National Academies Press. This book was released on 2004-11-27 with total page 88 pages. Available in PDF, EPUB and Kindle. Book excerpt: Within the last 30 years, the genomes of thousands of organisms, from viruses, to bacteria, to humans, have been sequenced or partially sequenced and deposited in databases freely accessible to scientists around the world. This information is accelerating scientists' ability to fight disease and make other medical advances, but policymakers must consider the possibility that the information could also be used for destructive purposes in acts of bioterrorism or war. Based in part on views from working biological scientists, the report concludes that current policies that allow scientists and the public unrestricted access to genome data on microbial pathogens should not be changed. Because access improves our ability to fight both bioterrorism and naturally occurring infectious diseases, security against bioterrorism is better served by policies that facilitate, not limit, the free flow of this information.

Genomic Surveillance and Pandemic Preparedness

Author : Rajesh Pandey
Publisher : Elsevier
ISBN 13 : 0443187681
Total Pages : 428 pages
Book Rating : 4.4/5 (431 download)

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Book Synopsis Genomic Surveillance and Pandemic Preparedness by : Rajesh Pandey

Download or read book Genomic Surveillance and Pandemic Preparedness written by Rajesh Pandey and published by Elsevier. This book was released on 2023-06-29 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genomic Surveillance and Pandemic Preparedness offers practical, in-depth instruction in where, how, and why genomic surveillance may be applied. Drawing heavily from the learnings during the COVID-19 pandemic, this book covers different aspects of microbes with a focus on viral genome sequencing and analysis, implementation and inference of genomic surveillance, and global data sharing best practices for future pandemic preparedness. Here, more than a dozen international authors consider host and pathogen genome interaction, population-level prevalence, individual disease susceptibility and gene protection, pathogen mutation evolutionary dynamics, RNA modulation of infection, pathogen diversity, and the role of coinfections and comorbidities in disease severity. A wide range of examples, from bacterial pathogens to fungal and viral infections, with an emphasis on recent COVID-19 analysis, are discussed. Finally, the authors provide step-by-step instruction in experimental and computational approaches for genomic surveillance, including nucleic acid isolation, sequencing library preparation, functional sequencing analysis, and bioinformatics pipelines. Throughout this book, importance is placed on inference—moving from genomic sequencing to meaningful genomic surveillance that bolsters pandemic preparedness. Highlights different aspects of genomic surveillance, from theory to implementation to inferences Covers a broad range of infectious diseases, with emphasis on recent COVID-19 studies Shares methods and approaches for sequencing-based pathogen detection, diagnostics, and surveillance Facilitates international collaboration in drug and vaccine development

Genetics and Evolution of Infectious Diseases

Author : Michel Tibayrenc
Publisher : Elsevier
ISBN 13 : 0443288194
Total Pages : 1002 pages
Book Rating : 4.4/5 (432 download)

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Book Synopsis Genetics and Evolution of Infectious Diseases by : Michel Tibayrenc

Download or read book Genetics and Evolution of Infectious Diseases written by Michel Tibayrenc and published by Elsevier. This book was released on 2024-07-19 with total page 1002 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetics and Evolution of Infectious Diseases, Third Edition discusses the evolving field of infectious diseases and their continued impact on the health of populations, especially in resource-limited areas of the world where they must confront the dual burden of death and disability due to infectious and chronic illnesses. Although substantial gains have been made in public health interventions for the treatment, prevention, and control of infectious diseases, in recent decades the world has witnessed the emergence of the human immunodeficiency virus (HIV) and the COVID-19 pandemic, increasing antimicrobial resistance, and the emergence of many new bacterial, fungal, parasitic, and viral pathogens. Fully updated and revised, this new edition presents the consequences of such diseases, the evolution of infectious diseases, the genetics of host-pathogen relationship, and the control and prevention strategies that are, or can be, developed. This book offers valuable information to biomedical researchers, clinicians, public health practitioners, decisions-makers, and students and postgraduates studying infectious diseases, microbiology, medicine, and public health that is relevant to the control and prevention of neglected and emerging worldwide diseases. Takes an integrated approach to infectious diseases Provides the latest developments in the field of infectious diseases Focuses on the contribution of evolutionary and genomic studies for the study and control of transmissible diseases Includes updated and revised contributions from leading authorities, along with six new chapters

Population Biology of Plant Pathogens

Author :
Publisher :
ISBN 13 :
Total Pages : 399 pages
Book Rating : 4.:/5 (915 download)

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Book Synopsis Population Biology of Plant Pathogens by :

Download or read book Population Biology of Plant Pathogens written by and published by . This book was released on 2015 with total page 399 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Genomics of Plant-Associated Bacteria

Author : Dennis C. Gross
Publisher : Springer
ISBN 13 : 3642553788
Total Pages : 283 pages
Book Rating : 4.6/5 (425 download)

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Book Synopsis Genomics of Plant-Associated Bacteria by : Dennis C. Gross

Download or read book Genomics of Plant-Associated Bacteria written by Dennis C. Gross and published by Springer. This book was released on 2014-06-16 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes how genomics has revolutionized our scientific understanding of agriculturally important plant-associated bacteria. Each chapter focuses on the genomics of particular bacteria: the first described plant pathogen, Erwinia amylovora; phytoplasmas lacking cell walls; fastidious, phloem-restricted liberibacters; Pseudomonas syringae, which is a genetically tractable model system; Xanthomonas citri, which causes a disease that can devastate citrus crops and Pseudomonas fluorescens, which can protect plants from diseases. Topics considered in this volume include the importance of horizontal gene transfer in originating new bacterial strains and species and advances in transcriptomics that allow us to describe the complex regulatory networks critical to plant-microbe interactions. The availability of the Xanthomonas oryzae genome has led to new technologies in genome editing, which will revolutionize approaches to genetic engineering, even in eukaryotes. The contributions show how genomics has greatly accelerated progress toward understanding the biology of these bacteria and how that understanding can be translated into novel crop protection methods.

Genomics of Plant–Pathogen Interaction and the Stress Response

Author : Ashutosh Mani
Publisher : CRC Press
ISBN 13 : 1000952436
Total Pages : 220 pages
Book Rating : 4.0/5 (9 download)

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Book Synopsis Genomics of Plant–Pathogen Interaction and the Stress Response by : Ashutosh Mani

Download or read book Genomics of Plant–Pathogen Interaction and the Stress Response written by Ashutosh Mani and published by CRC Press. This book was released on 2023-09-25 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plants are an indispensable part of human and animal lives for nutrition and health. But pests, diseases and abiotic stress adversely affect crop yield, which ultimately places significant pressure on society to provide food to an increasing population. Moreover, it also encourages increased chemical/pesticide usage on crops, which we see in the biomagnification of toxic and hazardous compounds polluting water bodies, soil and the environment. This condition will continue to worsen in the future due to the resistance-acquiring ability of pathogens against plant defense and chemical treatments. In addition, environmental disturbances and consumer health issues are being reported more promptly than before due to intensive use of pesticides in food production. Plant diseases affect our daily lives, as the use of insecticides and pesticides has become part of our food chain. As a result, precise disease diagnosis and management is crucial in order to avoid huge losses in plant production and related commodities. Accurate detection, precise diagnosis and proper management can play a significant role in keeping plants free from pathogens. In this book, scientists, researchers and scholars share their research knowledge, offering a valuable resource for understanding plant diseases, pathogen interaction and responses to stress through an omics perspective, contributing to further advancements in the field Diseases in plants may be caused by various factors, such as viruses, bacteria, fungi and abiotic stress. Disease causes low crop yield, production of poor-quality fruits and grains, and deficiency of nutrients, which have a direct impact on human and animal health. A genomics-based approach can be applied to disease diagnosis; disease outbreak; evolution of plant and pathogen genome for disease outbreak in relation to climate change; and development of long-term strategies for plant health and defense. This book presents an overview of omics technologies and approaches used to understand: the relation between plants and their environment in terms of diseases responses to abiotic stress the genomics of plant–pathogen interaction herbicide-resistance mechanisms the epigenetics of plant–pathogen interaction gene regulation during abiotic stress response the oxidative stress response

Bacterial Pathogen Genomics: Recent Achievements, Current Applications and Future Challenges

Author : Stephan Fuchs
Publisher : Frontiers Media SA
ISBN 13 : 2889766802
Total Pages : 194 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Bacterial Pathogen Genomics: Recent Achievements, Current Applications and Future Challenges by : Stephan Fuchs

Download or read book Bacterial Pathogen Genomics: Recent Achievements, Current Applications and Future Challenges written by Stephan Fuchs and published by Frontiers Media SA. This book was released on 2022-08-02 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Genomics of Foodborne Bacterial Pathogens

Author : Martin Wiedmann
Publisher : Springer Science & Business Media
ISBN 13 : 1441976868
Total Pages : 525 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Genomics of Foodborne Bacterial Pathogens by : Martin Wiedmann

Download or read book Genomics of Foodborne Bacterial Pathogens written by Martin Wiedmann and published by Springer Science & Business Media. This book was released on 2011-02-04 with total page 525 pages. Available in PDF, EPUB and Kindle. Book excerpt: Foodborne illnesses caused by various bacterial, viral, and fungal pathogens lead to a high number of morbidity and mortality in the U.S. and throughout the world. Recent advances in microbial genomics have significantly improved our understanding of the physiology, evolution, ecology, epidemiology, and pathogenesis of different foodborne pathogens. This book focuses on the genomics of foodborne bacterial pathogens. It begins with a brief overview of the recent advances in microbial genomics and the impact of genomics on food safety research. Then, eight chapters follow that elaborate some in-depth reviews on the genomics of several common foodborne bacterial pathogens including Bacillus, Campylobacter, Clostridium, Escherichia coli, Listeria, Salmonella, Staphylococcus, and Vibrio. Finally, the last four chapters focus on some current genomic, transcriptomic, and proteomic technologies and their applications in studying the epidemiology, evolution, and pathogenesis of foodborne bacterial pathogens. Genomics of Foodborne Bacterial Pathogens can be used as a reference by scientists and professionals in academia, government, and industry who are interested in understanding microbial genomics and using genomics tools to study foodborne bacterial pathogens. This book can also be used as a textbook for instructors and professors who teach food microbiology or microbial genomics-related courses at the post-graduate level.

Genomic Characterization of Emerging Human Fungal Pathogens

Author : Christina A. Cuomo
Publisher : Frontiers Media SA
ISBN 13 : 288966807X
Total Pages : 145 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Genomic Characterization of Emerging Human Fungal Pathogens by : Christina A. Cuomo

Download or read book Genomic Characterization of Emerging Human Fungal Pathogens written by Christina A. Cuomo and published by Frontiers Media SA. This book was released on 2021-05-25 with total page 145 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Genomes of Foodborne and Waterborne Pathogens

Author : Pina Fratamico
Publisher : American Society for Microbiology Press
ISBN 13 : 1555814573
Total Pages : 766 pages
Book Rating : 4.5/5 (558 download)

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Book Synopsis Genomes of Foodborne and Waterborne Pathogens by : Pina Fratamico

Download or read book Genomes of Foodborne and Waterborne Pathogens written by Pina Fratamico and published by American Society for Microbiology Press. This book was released on 2010-12-20 with total page 766 pages. Available in PDF, EPUB and Kindle. Book excerpt: Detailed interpretation of the environmental consequences of the latest findings from genome sequencing studies—presenting both scientific and public health opportunities. • Explains how understanding pathogen genomics can help ensure the safety of global food and water supplies. • Focuses on specific food- and waterborne pathogens that represent major public health threats. • Examines how global trends, such as climate change, increasing human populations, and rising levels of pollution, are stressing the ecosystems that food- and waterborne pathogens encounter, forcing them to adapt. • Serves as an excellent text for microbiology and genomics researchers, public health officials, regulators, food scientists, and other applicable professionals.

Genome Mapping and Genomics in Animal-Associated Microbes

Author : Vishvanath Nene
Publisher : Springer Science & Business Media
ISBN 13 : 3540740422
Total Pages : 253 pages
Book Rating : 4.5/5 (47 download)

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Book Synopsis Genome Mapping and Genomics in Animal-Associated Microbes by : Vishvanath Nene

Download or read book Genome Mapping and Genomics in Animal-Associated Microbes written by Vishvanath Nene and published by Springer Science & Business Media. This book was released on 2008-11-24 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt: Achievements and progress in genome mapping and the genomics of microbes supersede by far those for higher plants and animals, in part due to their enormous economic implication but also smaller genome size. In the post-genomic era, whole genome sequences of animal-associated microbes are providing clues to depicting the genetic basis of the complex host-pathogen relationships and the evolution of parasitism; and to improving methods of controlling pathogens. This volume focuses on a globally important group of intracellular prokaryotic pathogens which affect livestock animals. These include Brucella, Mycobacterium, Anaplasma and Ehrlichia, as well as the protozoan pathogens Cryptosporidium and Theileria, for which genome sequence data is available. Insights from comparative genomics of the microbes described provide clues to the adaptation involved in host-microbe interactions, as well as resources potentially useful for application in future research and product development.

The Applied Genomic Epidemiology Handbook

Author : Allison Black
Publisher : CRC Press
ISBN 13 : 100385382X
Total Pages : 165 pages
Book Rating : 4.0/5 (38 download)

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Book Synopsis The Applied Genomic Epidemiology Handbook by : Allison Black

Download or read book The Applied Genomic Epidemiology Handbook written by Allison Black and published by CRC Press. This book was released on 2024-03-18 with total page 165 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Applied Genomic Epidemiology Handbook: A Practical Guide to Leveraging Pathogen Genomic Data in Public Health provides rationale, theory, and implementation guidance to help public health practitioners incorporate pathogen genomic data analysis into their investigations. During the SARS-CoV-2 pandemic, viral whole genome sequences were generated, analyzed, and shared at an unprecedented scale. This wealth of data posed both tremendous opportunities and challenges; the data could be used to support varied parts of the public health response but could be hard for much of the public health workforce to analyze and interpret, given a historical lack of experience working with pathogen genomic data. This book addresses that gap. Structured into eight wide-ranging chapters, this book describes how the overlapping timescales of pathogen evolution and infection transmission enable exploration of epidemiologic dynamics from pathogen sequence data. Different approaches to sampling and genomic data inclusion are presented for different types of epidemiologic investigations. To support epidemiologists in diving into pathogen genomic data analysis, this book also introduces the analytic tools and approaches that are readily used in public health departments and presents case studies to show step-by-step how genomic data are used and evaluated in disease investigations. Despite the breadth of scientific literature that uses pathogen genomic data to investigate disease dynamics, there remains little practical guidance to help applied epidemiologists build their ability to explore epidemiologic questions with pathogen genomic data. This handbook was written to serve as that guide. Including case studies, common methods, and software tools, this book will be of great interest to public health microbiologists or lab directors, bioinformaticians, epidemiologists, health officers, academics, as well as students working in a public health context.

Fungal Genomics

Author : Jay C. Dunlap
Publisher : Elsevier
ISBN 13 : 0080474950
Total Pages : 316 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Fungal Genomics by : Jay C. Dunlap

Download or read book Fungal Genomics written by Jay C. Dunlap and published by Elsevier. This book was released on 2011-07-29 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: The sequencing of several fungi genomes has spurred major advances in the field. Fungal genomics has been having a pivotal impact on applied research in agriculture, food sciences, natural resource management, pharmaceuticals, and biotechnology, as well as to basic studies in the life sciences. Fungal Genomics covers exciting new developments in this growth field, from genomic analysis to human fungal pathogen genomics, comparative genomics of fungi, and the genomics of fungal development. Includes information on aspergillus genomes Discusses sex and its role in virulence of human fungal pathogens Covers the genomic analysis of neurospora

Genomics of Disease

Author : J.P. Gustafson
Publisher : Springer Science & Business Media
ISBN 13 : 0387767231
Total Pages : 232 pages
Book Rating : 4.3/5 (877 download)

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Book Synopsis Genomics of Disease by : J.P. Gustafson

Download or read book Genomics of Disease written by J.P. Gustafson and published by Springer Science & Business Media. This book was released on 2008-02-12 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: This title develops from the 24th Stadler symposium. It explores the general theme "GENOME EXPLOITATION: Data Mining the Genomes". The idea behind the theme is to discuss and illustrate how scientists are going to characterize and make use of the massive amount of information being accumulated about plant and animal genomes. The book presents a state-of-the-art picture on mining the Genome databases. Its chapters are authored by key stars in the field.