Paroxysmal Nocturnal Hemoglobinuria And Related Disorders

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Paroxysmal Nocturnal Hemoglobinuria and Related Disorders

Author : M. Omine
Publisher : Springer Science & Business Media
ISBN 13 : 4431678670
Total Pages : 376 pages
Book Rating : 4.4/5 (316 download)

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Book Synopsis Paroxysmal Nocturnal Hemoglobinuria and Related Disorders by : M. Omine

Download or read book Paroxysmal Nocturnal Hemoglobinuria and Related Disorders written by M. Omine and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: Few publications focus on the mysterious, genetically acquired disease paroxysmal nocturnal hemoglobinuria (PNH) and the related "intractable" disorders—aplastic anemia and myelodysplastic syndromes. Now, however, the latest understanding of the clinical and molecular genetic aspects of PNH is summarized here in the proceedings of the International Symposium held in Tokyo in 2001. Major topics reviewed include the molecular mechanisms of the PIG-A gene mutation; complement activation and inhibitors; experimental animal models; pathogenesis; the history of PNH research; the natural history of the disease; the mechanism of PNH clone expansion; the emergence of PNH clones under bone marrow failure syndromes; and treatment of the disease by immunosuppressive agents and stem cell transplantation. This book provides an invaluable summary of current research on the fundamental aspects of PNH pathology, presented by renowned experts in the field.

Paroxysmal Nocturnal Hemoglobinuria

Author : Yuzuru Kanakura
Publisher : Springer
ISBN 13 : 4431560033
Total Pages : 358 pages
Book Rating : 4.4/5 (315 download)

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Book Synopsis Paroxysmal Nocturnal Hemoglobinuria by : Yuzuru Kanakura

Download or read book Paroxysmal Nocturnal Hemoglobinuria written by Yuzuru Kanakura and published by Springer. This book was released on 2017-01-16 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume reviews the fundamental understanding of this potentially life-threatening disease and the advances in treatment that have been achieved with the use of the monoclonal antibody eculizumab. Although the PIGA gene has been known for many years, the mechanism of clonal dominance in paroxysmal nocturnal hemoglobinuria is still largely unknown. This book, Paroxysmal Nocturnal Hemoglobinuria, discusses the direction of continuing research in this area, as well as the potential for the development of management guidelines. It serves as a valuable source of information for both basic scientists and physicians, especially immunologists targeting GPI-anchored proteins and complements, and hematologists specializing in bone marrow failure.

NORD Guide to Rare Disorders

Author : National Organization for Rare Disorders
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 9780781730631
Total Pages : 982 pages
Book Rating : 4.7/5 (36 download)

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Book Synopsis NORD Guide to Rare Disorders by : National Organization for Rare Disorders

Download or read book NORD Guide to Rare Disorders written by National Organization for Rare Disorders and published by Lippincott Williams & Wilkins. This book was released on 2003 with total page 982 pages. Available in PDF, EPUB and Kindle. Book excerpt: NORD Guide to Rare Disorders is a comprehensive, practical, authoritative guide to the diagnosis and management of more than 800 rare diseases. The diseases are discussed in a uniform, easy-to-follow format--a brief description, signs and symptoms, etiology, related disorders, epidemiology, standard treatment, investigational treatment, resources, and references.The book includes a complete directory of orphan drugs, a full-color atlas of visual diagnostic signs, and a Master Resource List of support groups and helpful organizations. An index of symptoms and key words offers physicians valuable assistance in finding the information they need quickly.

Congenital and Acquired Bone Marrow Failure

Author : Mahmoud Deeb Aljurf
Publisher : Elsevier
ISBN 13 : 0128041757
Total Pages : 274 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Congenital and Acquired Bone Marrow Failure by : Mahmoud Deeb Aljurf

Download or read book Congenital and Acquired Bone Marrow Failure written by Mahmoud Deeb Aljurf and published by Elsevier. This book was released on 2016-12-23 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: Congenital and Acquired Bone Marrow Failure is a comprehensive guide to congenital and acquired bone marrow failure in adult and pediatric patients. Chapters are divided into two sections, acquired aplastic anemia and inherited bone marrow failure syndromes. Content ranges from the basic, to the translational, and from the epidemiology of acquired aplastic anemia and telomere biology, to the management, treatment, and supportive care of pediatric, adult, and geriatric patients. Contributors are world leading experts in the field of bone marrow failure. The book is required reading for residents, fellows, clinicians, and researchers across hematology, oncology, pathology, bone marrow transplantation, pediatrics, and internal medicine. Provides an overview of all congenital and acquired bone marrow failure syndromes Focuses on the molecular pathogenesis, clinical manifestation and diagnosis, laboratory features, and treatment of each disease within the syndromes Features the area of supportive care which is a topic of great interest to infectious disease physicians and those involved in transfusion services

PNH and the GPI-Linked Proteins

Author : Neal S. Young
Publisher : Elsevier
ISBN 13 : 9780080492094
Total Pages : 279 pages
Book Rating : 4.4/5 (92 download)

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Book Synopsis PNH and the GPI-Linked Proteins by : Neal S. Young

Download or read book PNH and the GPI-Linked Proteins written by Neal S. Young and published by Elsevier. This book was released on 2000-04-28 with total page 279 pages. Available in PDF, EPUB and Kindle. Book excerpt: Paroxysmal Nocturnal Hemoglobinuria (PNH) has been recognized for over a century. This mysterious disease is now understood at the level of the gene and the protein. The pathophysiology is related to a class of cell surface proteins with distinctive biochemical and physical characteristics. Recently it has been acknowledged that PNH is not rare, and once sensitive assays--based on the chemistry of the proteins--can be applied to many patients. Written by international experts in the field, this book includes a number of distinctive characteristics, such as the clinical features of PNH, the mechanism of hemolysis, the biochemistry of glycosylphosphoinositol anchors, and the chemistry and biophysics of GPI-anchored proteins. This unique and timely volume will have a wide audience, including hematologists and oncologists with a clinical interest in this disease, as well as basic biochemists, immunologists, and cell biologists studying this class of proteins. Outlines the chemical features of PNH Explains the mechanism of hemolysis Includes work on the biochemistry of glycophosphoinositol anchors Contains descriptions of the chemistry and biophysics of GPI-anchored proteins

The EBMT Handbook

Author : Nicolaus Kröger
Publisher :
ISBN 13 : 9781013273674
Total Pages : 688 pages
Book Rating : 4.2/5 (736 download)

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Book Synopsis The EBMT Handbook by : Nicolaus Kröger

Download or read book The EBMT Handbook written by Nicolaus Kröger and published by . This book was released on 2020-10-08 with total page 688 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Open Access edition of the European Society for Blood and Marrow Transplantation (EBMT) handbook addresses the latest developments and innovations in hematopoietic stem cell transplantation and cellular therapy. Consisting of 93 chapters, it has been written by 175 leading experts in the field. Discussing all types of stem cell and bone marrow transplantation, including haplo-identical stem cell and cord blood transplantation, it also covers the indications for transplantation, the management of early and late complications as well as the new and rapidly evolving field of cellular therapies. This book provides an unparalleled description of current practices to enhance readers' knowledge and practice skills. This work was published by Saint Philip Street Press pursuant to a Creative Commons license permitting commercial use. All rights not granted by the work's license are retained by the author or authors.

Clinical Cytometry

Author : Michael Andreeff
Publisher :
ISBN 13 :
Total Pages : 424 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Clinical Cytometry by : Michael Andreeff

Download or read book Clinical Cytometry written by Michael Andreeff and published by . This book was released on 1986 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Allogeneic Stem Cell Transplantation

Author : Hillard M. Lazarus
Publisher : Springer Science & Business Media
ISBN 13 : 1597454788
Total Pages : 885 pages
Book Rating : 4.5/5 (974 download)

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Book Synopsis Allogeneic Stem Cell Transplantation by : Hillard M. Lazarus

Download or read book Allogeneic Stem Cell Transplantation written by Hillard M. Lazarus and published by Springer Science & Business Media. This book was released on 2010-03-02 with total page 885 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the original publication of Allogeneic Stem Cell Transplantation: Clinical Research and Practice, Allogeneic hematopoietic stem cell transplantation (HSC) has undergone several fast-paced changes. In this second edition, the editors have focused on topics relevant to evolving knowledge in the field in order to better guide clinicians in decision-making and management of their patients, as well as help lead laboratory investigators in new directions emanating from clinical observations. Some of the most respected clinicians and scientists in this discipline have responded to the recent advances in the field by providing state-of-the-art discussions addressing these topics in the second edition. The text covers the scope of human genomic variation, the methods of HLA typing and interpretation of high-resolution HLA results. Comprehensive and up-to-date, Allogeneic Stem Cell Transplantation: Clinical Research and Practice, Second Edition offers concise advice on today's best clinical practice and will be of significant benefit to all clinicians and researchers in allogeneic HSC transplantation.

Handbook of Benign Hematology

Author : Martha Pritchett Mims, MD, PhD
Publisher : Springer Publishing Company
ISBN 13 : 0826149871
Total Pages : 555 pages
Book Rating : 4.8/5 (261 download)

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Book Synopsis Handbook of Benign Hematology by : Martha Pritchett Mims, MD, PhD

Download or read book Handbook of Benign Hematology written by Martha Pritchett Mims, MD, PhD and published by Springer Publishing Company. This book was released on 2019-12-11 with total page 555 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Benign Hematology is a practical guide to the diagnosis and management of benign hematologic conditions. The book begins with a chapter on normal hematopoiesis and follows with chapters devoted to groups of blood disorders and syndromes including neutrophil disorders, nonmalignant myeloid disorders, bone marrow failure syndromes, myeloproliferative disorders, anemias, iron metabolism disorders, platelet disorders, hemostasis and coagulation defects, and thrombosis. Each disorder subtype covered features a clinical case, an introduction to the condition, details on diagnosis including applicable criteria and lab work needed, key diagnostic dilemmas, prognosis, treatment options, details on clinical trials and emerging clinical strategies, and bulleted key points to highlight clinical pearls and common pitfalls. The final chapters provide best practices for transfusion medicine and a guide to pharmacologic agents and their uses in clinical practice for adult and pediatric patients. The handbook is filled with tables and illustrations which highlight FDA-approved drug information, clinical trials data, hematopathologic characteristics of different disorders, important management criteria and more, making it the ideal handbook for those in practice or for review. The Editors and chapter authors are experienced academic practitioners in the fields of adult and pediatric hematology, pathology, blood banking, and pharmacology. Emphasizing best practices for patient management, this handbook is essential for oncologists, hematologists, trainees, and other practitioners who regularly or increasingly receive referrals to diagnose and treat adults or children with nonmalignant hematologic conditions. Key Features: Includes dozens of clinical cases covering all nonmalignant blood disorders Emphasizes patient management and best practices for disorders seen in adults and children Contains over 30 color images and numerous tables for quick reference Presents important details of all pharmacologic agents used to treat or manage hematologic disorders and their complications Purchase includes access to the ebook for use on most mobile devices or computers

Budd-Chiari Syndrome

Author : Xingshun Qi
Publisher : Springer Nature
ISBN 13 : 9813292326
Total Pages : 252 pages
Book Rating : 4.8/5 (132 download)

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Book Synopsis Budd-Chiari Syndrome by : Xingshun Qi

Download or read book Budd-Chiari Syndrome written by Xingshun Qi and published by Springer Nature. This book was released on 2019-11-13 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers a systematic introduction to Budd-Chiari syndrome, a rare but life-threatening vascular disorder of the liver, which refers to obstructions at any site from the hepatic veins to the suprahepatic inferior vena cava. The book mainly covers the history, epidemiology, etiology and risk factors, pathology, diagnosis, pharmacological and interventional aspects, surgical treatment, etiological treatment, and prognostic assessment of Budd-Chiari syndrome. Notably, it also presents cutting-edge research findings in this field. The early diagnosis of Budd-Chiari syndrome is vital, as it allows clinicians to pursue more targeted and effective treatment strategies, thus improving patient outcomes. However, much information, including the latest advances, has not yet been fully disseminated in current clinical practice. This book addresses that gap, helping physicians to improve diagnosis and establish standard treatment strategies, helping researchers conduct clinical and experimental studies, and even helping patients and their relatives to recognize this disease.

Hematology

Author : Ronald Hoffman
Publisher :
ISBN 13 : 9780443066283
Total Pages : 2821 pages
Book Rating : 4.0/5 (662 download)

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Book Synopsis Hematology by : Ronald Hoffman

Download or read book Hematology written by Ronald Hoffman and published by . This book was released on 2005 with total page 2821 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Blood Banking and Transfusion Medicine

Author : Christopher D. Hillyer
Publisher : Elsevier Health Sciences
ISBN 13 : 0443069816
Total Pages : 910 pages
Book Rating : 4.4/5 (43 download)

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Book Synopsis Blood Banking and Transfusion Medicine by : Christopher D. Hillyer

Download or read book Blood Banking and Transfusion Medicine written by Christopher D. Hillyer and published by Elsevier Health Sciences. This book was released on 2006-10-18 with total page 910 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ever since the discovery of blood types early in the last century, transfusion medicine has evolved at a breakneck pace. This second edition of Blood Banking and Transfusion Medicine is exactly what you need to keep up. It combines scientific foundations with today's most practical approaches to the specialty. From blood collection and storage to testing and transfusing blood components, and finally cellular engineering, you'll find coverage here that's second to none. New advances in molecular genetics and the scientific mechanisms underlying the field are also covered, with an emphasis on the clinical implications for treatment. Whether you're new to the field or an old pro, this book belongs in your reference library. Integrates scientific foundations with clinical relevance to more clearly explain the science and its application to clinical practice. Highlights advances in the use of blood products and new methods of disease treatment while providing the most up-to-date information on these fast-moving topics Discusses current clinical controversies, providing an arena for the discussion of sensitive topics. Covers the constantly changing approaches to stem cell transplantation and brings you the latest information on this controversial topic.

Bone Marrow Pathology

Author : Barbara J. Bain
Publisher : John Wiley & Sons
ISBN 13 : 0470756896
Total Pages : 513 pages
Book Rating : 4.4/5 (77 download)

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Book Synopsis Bone Marrow Pathology by : Barbara J. Bain

Download or read book Bone Marrow Pathology written by Barbara J. Bain and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 513 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by one of the world's leading haematologists, and three renowned histopathologists, Bone Marrow Pathology provides a comprehensive guide to the diagnosis of bone marrow disease. Now in its Third Edition, the text has been extensively revised and rewritten to reflect the latest advances in the field. Features: An extremely practical, up-to-the-minute text incorporating the new WHO classification of haematopoietic malignancies A comprehensive text written with great precision and clarity of style Incorporates a new section 'Problems and Pitfalls' - a unique section that will aid the working pathologist faced with a difficult situation An important text for the haematologist, histopathologist and haematopathologist with equal weight given to peripheral blood, aspirate, trephine biology and specialized techniques Extensively illustrated with many of the photographs being of paraffin-embedded sections Combines all the techniques now applied to bone marrow diagnosis, including immunocytochemistry, flow cytometery, immunohistochemistry and the diagnostic role of cytogenetic and molecular genetic analysis

SickKids Handbook of Pediatric Thrombosis and Hemostasis

Author : Victor S. Blanchette
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318021970
Total Pages : 274 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis SickKids Handbook of Pediatric Thrombosis and Hemostasis by : Victor S. Blanchette

Download or read book SickKids Handbook of Pediatric Thrombosis and Hemostasis written by Victor S. Blanchette and published by Karger Medical and Scientific Publishers. This book was released on 2013 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: SickKids Handbook of Pediatric Thrombosis and Hemostasis takes the reader through the entire field of paediatric thrombosis and hemostasis. This practical reference book will be a convenient, comprehensive, source of information and provides up-to-date, evidence-based guidance in the diagnosis and management of inherited and acquired bleeding disorders and thrombotic events of the venous, arterial, cardiac and central nervous systems that affect children, including the neonate. Written and reviewed by international experts in the field, SickKids Handbook of Pediatric Thrombosis and Hemostasis will guide health care professionals involved in the assessment and care of children with all types of bleeding and clotting disorders, including general and specialist pediatricians, in particular intensivists, neonatologists, cardiologists/cardiac surgeons, rheumatologists and nephrologists; hematologists/oncologists as well as nurses, nurse practitioners and pharmacists. Written in a user-friendly, algorithmic approach, the resource will serve students and trainees and assist teachers in developing practical lessons.

Disorders of Hemoglobin

Author : Martin H. Steinberg
Publisher : Cambridge University Press
ISBN 13 : 0521875196
Total Pages : 883 pages
Book Rating : 4.5/5 (218 download)

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Book Synopsis Disorders of Hemoglobin by : Martin H. Steinberg

Download or read book Disorders of Hemoglobin written by Martin H. Steinberg and published by Cambridge University Press. This book was released on 2009-08-17 with total page 883 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completely revised new edition of the definitive reference on disorders of hemoglobin.

Liver Anesthesiology and Critical Care Medicine

Author : Gebhard Wagener
Publisher : Springer
ISBN 13 : 3319642987
Total Pages : 542 pages
Book Rating : 4.3/5 (196 download)

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Book Synopsis Liver Anesthesiology and Critical Care Medicine by : Gebhard Wagener

Download or read book Liver Anesthesiology and Critical Care Medicine written by Gebhard Wagener and published by Springer. This book was released on 2018-04-11 with total page 542 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing anesthesiology for liver surgery and especially liver transplantation is highly complex and requires profound expertise in the physiology and pathophysiology of liver disease. This new edition incorporates the latest information in the field and remains the only available book on the topic. It focuses on the practical aspect of liver anesthesiology and critical care, while providing a comprehensive and in depth summary of the knowledge in this field. Most liver transplant centers now have dedicated teams providing anesthesia care during liver transplantations. In the last years there has been a substantial increase in knowledge and improvement in techniques in anesthesiology and critical care of patients undergoing liver surgery and transplant patients. Liver Anesthesiology and Critical Care Medicine, 2nd Edition includes new chapters on chronic liver failure and hepatic cirrhosis, preoperative risk assessment, evidence in liver anesthesiology, the splanchnic and systemic circulation in liver disease and a special focus on analgesia for liver resection including regional techniques. Written for anesthesiologists and critical care physicians caring for patients undergoing liver surgery and transplantation, this book proves to be an essential companion and review book as the number of liver surgeries with higher complexity continue to increase.

Ferri's Clinical Advisor 2021

Author : Fred F. Ferri
Publisher : Elsevier Health Sciences
ISBN 13 : 0323713343
Total Pages : 4158 pages
Book Rating : 4.3/5 (237 download)

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Book Synopsis Ferri's Clinical Advisor 2021 by : Fred F. Ferri

Download or read book Ferri's Clinical Advisor 2021 written by Fred F. Ferri and published by Elsevier Health Sciences. This book was released on 2020-06-10 with total page 4158 pages. Available in PDF, EPUB and Kindle. Book excerpt: Find fast answers to inform your daily diagnosis and treatment decisions! Ferri’s Clinical Advisor 2021 uses the popular "5 books in 1" format to deliver vast amounts of information in a clinically relevant, user-friendly manner. This bestselling reference has been significantly updated to provide you with easy access to answers on 1,000 common medical conditions, including diseases and disorders, differential diagnoses, clinical algorithms, laboratory tests, and clinical practice guidelines—all carefully reviewed by experts in key clinical fields. Extensive algorithms, along with hundreds of new figures and tables, ensure that you stay current with today's medical practice. Contains significant updates throughout, covering all aspects of current diagnosis and treatment. Features 27 all-new topics including chronic rhinosinusitis, subclinical brain infarction, reflux-cough syndrome, radiation pneumonitis, catatonia, end-stage renal disease, and genitourinary syndrome of menopause, among others. Includes new appendices covering common herbs in integrated medicine and herbal activities against pain and chronic diseases; palliative care; and preoperative evaluation. Offers online access to Patient Teaching Guides in both English and Spanish.