Analysis of Generalized Linear Mixed Models in the Agricultural and Natural Resources Sciences

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Publisher : John Wiley & Sons
ISBN 13 : 0891181822
Total Pages : 304 pages
Book Rating : 4.8/5 (911 download)

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Book Synopsis Analysis of Generalized Linear Mixed Models in the Agricultural and Natural Resources Sciences by : Edward E. Gbur

Download or read book Analysis of Generalized Linear Mixed Models in the Agricultural and Natural Resources Sciences written by Edward E. Gbur and published by John Wiley & Sons. This book was released on 2020-01-22 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: Generalized Linear Mixed Models in the Agricultural and Natural Resources Sciences provides readers with an understanding and appreciation for the design and analysis of mixed models for non-normally distributed data. It is the only publication of its kind directed specifically toward the agricultural and natural resources sciences audience. Readers will especially benefit from the numerous worked examples based on actual experimental data and the discussion of pitfalls associated with incorrect analyses.

Generalized Linear Mixed Models with Applications in Agriculture and Biology

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Publisher : Springer Nature
ISBN 13 : 3031328000
Total Pages : 436 pages
Book Rating : 4.0/5 (313 download)

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Book Synopsis Generalized Linear Mixed Models with Applications in Agriculture and Biology by : Josafhat Salinas Ruíz

Download or read book Generalized Linear Mixed Models with Applications in Agriculture and Biology written by Josafhat Salinas Ruíz and published by Springer Nature. This book was released on 2023-08-16 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book offers an introduction to mixed generalized linear models with applications to the biological sciences, basically approached from an applications perspective, without neglecting the rigor of the theory. For this reason, the theory that supports each of the studied methods is addressed and later - through examples - its application is illustrated. In addition, some of the assumptions and shortcomings of linear statistical models in general are also discussed. An alternative to analyse non-normal distributed response variables is the use of generalized linear models (GLM) to describe the response data with an exponential family distribution that perfectly fits the real response. Extending this idea to models with random effects allows the use of Generalized Linear Mixed Models (GLMMs). The use of these complex models was not computationally feasible until the recent past, when computational advances and improvements to statistical analysis programs allowed users to easily, quickly, and accurately apply GLMM to data sets. GLMMs have attracted considerable attention in recent years. The word "Generalized" refers to non-normal distributions for the response variable and the word "Mixed" refers to random effects, in addition to the fixed effects typical of analysis of variance (or regression). With the development of modern statistical packages such as Statistical Analysis System (SAS), R, ASReml, among others, a wide variety of statistical analyzes are available to a wider audience. However, to be able to handle and master more sophisticated models requires proper training and great responsibility on the part of the practitioner to understand how these advanced tools work. GMLM is an analysis methodology used in agriculture and biology that can accommodate complex correlation structures and types of response variables.

Bayesian Filtering and Smoothing

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Publisher : Cambridge University Press
ISBN 13 : 110703065X
Total Pages : 255 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis Bayesian Filtering and Smoothing by : Simo Särkkä

Download or read book Bayesian Filtering and Smoothing written by Simo Särkkä and published by Cambridge University Press. This book was released on 2013-09-05 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: A unified Bayesian treatment of the state-of-the-art filtering, smoothing, and parameter estimation algorithms for non-linear state space models.

Monte Carlo and Quasi-Monte Carlo Methods 2012

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Publisher : Springer Science & Business Media
ISBN 13 : 3642410952
Total Pages : 680 pages
Book Rating : 4.6/5 (424 download)

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Book Synopsis Monte Carlo and Quasi-Monte Carlo Methods 2012 by : Josef Dick

Download or read book Monte Carlo and Quasi-Monte Carlo Methods 2012 written by Josef Dick and published by Springer Science & Business Media. This book was released on 2013-12-05 with total page 680 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book represents the refereed proceedings of the Tenth International Conference on Monte Carlo and Quasi-Monte Carlo Methods in Scientific Computing that was held at the University of New South Wales (Australia) in February 2012. These biennial conferences are major events for Monte Carlo and the premiere event for quasi-Monte Carlo research. The proceedings include articles based on invited lectures as well as carefully selected contributed papers on all theoretical aspects and applications of Monte Carlo and quasi-Monte Carlo methods. The reader will be provided with information on latest developments in these very active areas. The book is an excellent reference for theoreticians and practitioners interested in solving high-dimensional computational problems arising, in particular, in finance, statistics and computer graphics.

Monte-Carlo Simulation-Based Statistical Modeling

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Publisher : Springer
ISBN 13 : 9811033072
Total Pages : 440 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Monte-Carlo Simulation-Based Statistical Modeling by : Ding-Geng (Din) Chen

Download or read book Monte-Carlo Simulation-Based Statistical Modeling written by Ding-Geng (Din) Chen and published by Springer. This book was released on 2017-02-01 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book brings together expert researchers engaged in Monte-Carlo simulation-based statistical modeling, offering them a forum to present and discuss recent issues in methodological development as well as public health applications. It is divided into three parts, with the first providing an overview of Monte-Carlo techniques, the second focusing on missing data Monte-Carlo methods, and the third addressing Bayesian and general statistical modeling using Monte-Carlo simulations. The data and computer programs used here will also be made publicly available, allowing readers to replicate the model development and data analysis presented in each chapter, and to readily apply them in their own research. Featuring highly topical content, the book has the potential to impact model development and data analyses across a wide spectrum of fields, and to spark further research in this direction.

Generalized Latent Variable Modeling

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Publisher : CRC Press
ISBN 13 : 0203489438
Total Pages : 523 pages
Book Rating : 4.2/5 (34 download)

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Book Synopsis Generalized Latent Variable Modeling by : Anders Skrondal

Download or read book Generalized Latent Variable Modeling written by Anders Skrondal and published by CRC Press. This book was released on 2004-05-11 with total page 523 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book unifies and extends latent variable models, including multilevel or generalized linear mixed models, longitudinal or panel models, item response or factor models, latent class or finite mixture models, and structural equation models. Following a gentle introduction to latent variable modeling, the authors clearly explain and contrast a wi

Generalized Linear Models

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Publisher : John Wiley & Sons
ISBN 13 : 0470556978
Total Pages : 521 pages
Book Rating : 4.4/5 (75 download)

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Book Synopsis Generalized Linear Models by : Raymond H. Myers

Download or read book Generalized Linear Models written by Raymond H. Myers and published by John Wiley & Sons. This book was released on 2012-01-20 with total page 521 pages. Available in PDF, EPUB and Kindle. Book excerpt: Praise for the First Edition "The obvious enthusiasm of Myers, Montgomery, and Vining and their reliance on their many examples as a major focus of their pedagogy make Generalized Linear Models a joy to read. Every statistician working in any area of applied science should buy it and experience the excitement of these new approaches to familiar activities." —Technometrics Generalized Linear Models: With Applications in Engineering and the Sciences, Second Edition continues to provide a clear introduction to the theoretical foundations and key applications of generalized linear models (GLMs). Maintaining the same nontechnical approach as its predecessor, this update has been thoroughly extended to include the latest developments, relevant computational approaches, and modern examples from the fields of engineering and physical sciences. This new edition maintains its accessible approach to the topic by reviewing the various types of problems that support the use of GLMs and providing an overview of the basic, related concepts such as multiple linear regression, nonlinear regression, least squares, and the maximum likelihood estimation procedure. Incorporating the latest developments, new features of this Second Edition include: A new chapter on random effects and designs for GLMs A thoroughly revised chapter on logistic and Poisson regression, now with additional results on goodness of fit testing, nominal and ordinal responses, and overdispersion A new emphasis on GLM design, with added sections on designs for regression models and optimal designs for nonlinear regression models Expanded discussion of weighted least squares, including examples that illustrate how to estimate the weights Illustrations of R code to perform GLM analysis The authors demonstrate the diverse applications of GLMs through numerous examples, from classical applications in the fields of biology and biopharmaceuticals to more modern examples related to engineering and quality assurance. The Second Edition has been designed to demonstrate the growing computational nature of GLMs, as SAS®, Minitab®, JMP®, and R software packages are used throughout the book to demonstrate fitting and analysis of generalized linear models, perform inference, and conduct diagnostic checking. Numerous figures and screen shots illustrating computer output are provided, and a related FTP site houses supplementary material, including computer commands and additional data sets. Generalized Linear Models, Second Edition is an excellent book for courses on regression analysis and regression modeling at the upper-undergraduate and graduate level. It also serves as a valuable reference for engineers, scientists, and statisticians who must understand and apply GLMs in their work.

Generalized, Linear, and Mixed Models

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Publisher : John Wiley & Sons
ISBN 13 : 1118209966
Total Pages : 281 pages
Book Rating : 4.1/5 (182 download)

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Book Synopsis Generalized, Linear, and Mixed Models by : Charles E. McCulloch

Download or read book Generalized, Linear, and Mixed Models written by Charles E. McCulloch and published by John Wiley & Sons. This book was released on 2011-09-20 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: An accessible and self-contained introduction to statistical models-now in a modernized new edition Generalized, Linear, and Mixed Models, Second Edition provides an up-to-date treatment of the essential techniques for developing and applying a wide variety of statistical models. The book presents thorough and unified coverage of the theory behind generalized, linear, and mixed models and highlights their similarities and differences in various construction, application, and computational aspects. A clear introduction to the basic ideas of fixed effects models, random effects models, and mixed models is maintained throughout, and each chapter illustrates how these models are applicable in a wide array of contexts. In addition, a discussion of general methods for the analysis of such models is presented with an emphasis on the method of maximum likelihood for the estimation of parameters. The authors also provide comprehensive coverage of the latest statistical models for correlated, non-normally distributed data. Thoroughly updated to reflect the latest developments in the field, the Second Edition features: A new chapter that covers omitted covariates, incorrect random effects distribution, correlation of covariates and random effects, and robust variance estimation A new chapter that treats shared random effects models, latent class models, and properties of models A revised chapter on longitudinal data, which now includes a discussion of generalized linear models, modern advances in longitudinal data analysis, and the use between and within covariate decompositions Expanded coverage of marginal versus conditional models Numerous new and updated examples With its accessible style and wealth of illustrative exercises, Generalized, Linear, and Mixed Models, Second Edition is an ideal book for courses on generalized linear and mixed models at the upper-undergraduate and beginning-graduate levels. It also serves as a valuable reference for applied statisticians, industrial practitioners, and researchers.

Foundations of Linear and Generalized Linear Models

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Publisher : John Wiley & Sons
ISBN 13 : 1118730038
Total Pages : 471 pages
Book Rating : 4.1/5 (187 download)

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Book Synopsis Foundations of Linear and Generalized Linear Models by : Alan Agresti

Download or read book Foundations of Linear and Generalized Linear Models written by Alan Agresti and published by John Wiley & Sons. This book was released on 2015-02-23 with total page 471 pages. Available in PDF, EPUB and Kindle. Book excerpt: A valuable overview of the most important ideas and results in statistical modeling Written by a highly-experienced author, Foundations of Linear and Generalized Linear Models is a clear and comprehensive guide to the key concepts and results of linearstatistical models. The book presents a broad, in-depth overview of the most commonly usedstatistical models by discussing the theory underlying the models, R software applications,and examples with crafted models to elucidate key ideas and promote practical modelbuilding. The book begins by illustrating the fundamentals of linear models, such as how the model-fitting projects the data onto a model vector subspace and how orthogonal decompositions of the data yield information about the effects of explanatory variables. Subsequently, the book covers the most popular generalized linear models, which include binomial and multinomial logistic regression for categorical data, and Poisson and negative binomial loglinear models for count data. Focusing on the theoretical underpinnings of these models, Foundations ofLinear and Generalized Linear Models also features: An introduction to quasi-likelihood methods that require weaker distributional assumptions, such as generalized estimating equation methods An overview of linear mixed models and generalized linear mixed models with random effects for clustered correlated data, Bayesian modeling, and extensions to handle problematic cases such as high dimensional problems Numerous examples that use R software for all text data analyses More than 400 exercises for readers to practice and extend the theory, methods, and data analysis A supplementary website with datasets for the examples and exercises An invaluable textbook for upper-undergraduate and graduate-level students in statistics and biostatistics courses, Foundations of Linear and Generalized Linear Models is also an excellent reference for practicing statisticians and biostatisticians, as well as anyone who is interested in learning about the most important statistical models for analyzing data.

Analysis of Mixed Data

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Publisher : CRC Press
ISBN 13 : 1439884722
Total Pages : 262 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Analysis of Mixed Data by : Alexander R. de Leon

Download or read book Analysis of Mixed Data written by Alexander R. de Leon and published by CRC Press. This book was released on 2013-01-16 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive source on mixed data analysis, Analysis of Mixed Data: Methods & Applications summarizes the fundamental developments in the field. Case studies are used extensively throughout the book to illustrate interesting applications from economics, medicine and health, marketing, and genetics. Carefully edited for smooth readability and

Foundations of Linear and Generalized Linear Models

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Publisher : John Wiley & Sons
ISBN 13 : 1118730305
Total Pages : 480 pages
Book Rating : 4.1/5 (187 download)

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Book Synopsis Foundations of Linear and Generalized Linear Models by : Alan Agresti

Download or read book Foundations of Linear and Generalized Linear Models written by Alan Agresti and published by John Wiley & Sons. This book was released on 2015-01-15 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: A valuable overview of the most important ideas and results in statistical modeling Written by a highly-experienced author, Foundations of Linear and Generalized Linear Models is a clear and comprehensive guide to the key concepts and results of linearstatistical models. The book presents a broad, in-depth overview of the most commonly usedstatistical models by discussing the theory underlying the models, R software applications,and examples with crafted models to elucidate key ideas and promote practical modelbuilding. The book begins by illustrating the fundamentals of linear models, such as how the model-fitting projects the data onto a model vector subspace and how orthogonal decompositions of the data yield information about the effects of explanatory variables. Subsequently, the book covers the most popular generalized linear models, which include binomial and multinomial logistic regression for categorical data, and Poisson and negative binomial loglinear models for count data. Focusing on the theoretical underpinnings of these models, Foundations ofLinear and Generalized Linear Models also features: An introduction to quasi-likelihood methods that require weaker distributional assumptions, such as generalized estimating equation methods An overview of linear mixed models and generalized linear mixed models with random effects for clustered correlated data, Bayesian modeling, and extensions to handle problematic cases such as high dimensional problems Numerous examples that use R software for all text data analyses More than 400 exercises for readers to practice and extend the theory, methods, and data analysis A supplementary website with datasets for the examples and exercises An invaluable textbook for upper-undergraduate and graduate-level students in statistics and biostatistics courses, Foundations of Linear and Generalized Linear Models is also an excellent reference for practicing statisticians and biostatisticians, as well as anyone who is interested in learning about the most important statistical models for analyzing data.

Linear and Generalized Linear Mixed Models and Their Applications

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Publisher : Springer Science & Business Media
ISBN 13 : 0387479465
Total Pages : 269 pages
Book Rating : 4.3/5 (874 download)

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Book Synopsis Linear and Generalized Linear Mixed Models and Their Applications by : Jiming Jiang

Download or read book Linear and Generalized Linear Mixed Models and Their Applications written by Jiming Jiang and published by Springer Science & Business Media. This book was released on 2007-05-30 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers two major classes of mixed effects models, linear mixed models and generalized linear mixed models. It presents an up-to-date account of theory and methods in analysis of these models as well as their applications in various fields. The book offers a systematic approach to inference about non-Gaussian linear mixed models. Furthermore, it includes recently developed methods, such as mixed model diagnostics, mixed model selection, and jackknife method in the context of mixed models. The book is aimed at students, researchers and other practitioners who are interested in using mixed models for statistical data analysis.

Analysis of Generalized Linear Mixed Models in the Agricultural and Natural Resources Sciences

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Publisher :
ISBN 13 : 9780891181835
Total Pages : 283 pages
Book Rating : 4.1/5 (818 download)

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Book Synopsis Analysis of Generalized Linear Mixed Models in the Agricultural and Natural Resources Sciences by : Edward E. Gbur

Download or read book Analysis of Generalized Linear Mixed Models in the Agricultural and Natural Resources Sciences written by Edward E. Gbur and published by . This book was released on 2012 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: Generalized Linear Mixed Models in the Agricultural and Natural Resources Sciences provides readers with an understanding and appreciation for the design and analysis of mixed models for non-normally distributed data. It is the only publication of its kind directed specifically toward the agricultural and natural resources sciences audience. Readers will especially benefit from the numerous worked examples based on actual experimental data and the discussion of pitfalls associated with incorrect analyses.

Mixed Models

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Publisher : John Wiley & Sons
ISBN 13 : 1118091574
Total Pages : 768 pages
Book Rating : 4.1/5 (18 download)

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Book Synopsis Mixed Models by : Eugene Demidenko

Download or read book Mixed Models written by Eugene Demidenko and published by John Wiley & Sons. This book was released on 2013-08-05 with total page 768 pages. Available in PDF, EPUB and Kindle. Book excerpt: Praise for the First Edition “This book will serve to greatly complement the growing number of texts dealing with mixed models, and I highly recommend including it in one’s personal library.” —Journal of the American Statistical Association Mixed modeling is a crucial area of statistics, enabling the analysis of clustered and longitudinal data. Mixed Models: Theory and Applications with R, Second Edition fills a gap in existing literature between mathematical and applied statistical books by presenting a powerful examination of mixed model theory and application with special attention given to the implementation in R. The new edition provides in-depth mathematical coverage of mixed models’ statistical properties and numerical algorithms, as well as nontraditional applications, such as regrowth curves, shapes, and images. The book features the latest topics in statistics including modeling of complex clustered or longitudinal data, modeling data with multiple sources of variation, modeling biological variety and heterogeneity, Healthy Akaike Information Criterion (HAIC), parameter multidimensionality, and statistics of image processing. Mixed Models: Theory and Applications with R, Second Edition features unique applications of mixed model methodology, as well as: Comprehensive theoretical discussions illustrated by examples and figures Over 300 exercises, end-of-section problems, updated data sets, and R subroutines Problems and extended projects requiring simulations in R intended to reinforce material Summaries of major results and general points of discussion at the end of each chapter Open problems in mixed modeling methodology, which can be used as the basis for research or PhD dissertations Ideal for graduate-level courses in mixed statistical modeling, the book is also an excellent reference for professionals in a range of fields, including cancer research, computer science, and engineering.

Generalized Linear Mixed Models

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Publisher : IMS
ISBN 13 : 9780940600546
Total Pages : 100 pages
Book Rating : 4.6/5 (5 download)

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Book Synopsis Generalized Linear Mixed Models by : Charles E. McCulloch

Download or read book Generalized Linear Mixed Models written by Charles E. McCulloch and published by IMS. This book was released on 2003 with total page 100 pages. Available in PDF, EPUB and Kindle. Book excerpt: Wiley Series in Probability and Statistics A modern perspective on mixed models The availability of powerful computing methods in recent decades has thrust linear and nonlinear mixed models into the mainstream of statistical application. This volume offers a modern perspective on generalized, linear, and mixed models, presenting a unified and accessible treatment of the newest statistical methods for analyzing correlated, nonnormally distributed data. As a follow-up to Searle's classic, Linear Models, and Variance Components by Searle, Casella, and McCulloch, this new work progresses from the basic one-way classification to generalized linear mixed models. A variety of statistical methods are explained and illustrated, with an emphasis on maximum likelihood and restricted maximum likelihood. An invaluable resource for applied statisticians and industrial practitioners, as well as students interested in the latest results, Generalized, Linear, and Mixed Models features: * A review of the basics of linear models and linear mixed models * Descriptions of models for nonnormal data, including generalized linear and nonlinear models * Analysis and illustration of techniques for a variety of real data sets * Information on the accommodation of longitudinal data using these models * Coverage of the prediction of realized values of random effects * A discussion of the impact of computing issues on mixed models

Mixed Effects Models for Complex Data

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Publisher : CRC Press
ISBN 13 : 9781420074086
Total Pages : 431 pages
Book Rating : 4.0/5 (74 download)

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Book Synopsis Mixed Effects Models for Complex Data by : Lang Wu

Download or read book Mixed Effects Models for Complex Data written by Lang Wu and published by CRC Press. This book was released on 2009-11-11 with total page 431 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although standard mixed effects models are useful in a range of studies, other approaches must often be used in correlation with them when studying complex or incomplete data. Mixed Effects Models for Complex Data discusses commonly used mixed effects models and presents appropriate approaches to address dropouts, missing data, measurement errors, censoring, and outliers. For each class of mixed effects model, the author reviews the corresponding class of regression model for cross-sectional data. An overview of general models and methods, along with motivating examples After presenting real data examples and outlining general approaches to the analysis of longitudinal/clustered data and incomplete data, the book introduces linear mixed effects (LME) models, generalized linear mixed models (GLMMs), nonlinear mixed effects (NLME) models, and semiparametric and nonparametric mixed effects models. It also includes general approaches for the analysis of complex data with missing values, measurement errors, censoring, and outliers. Self-contained coverage of specific topics Subsequent chapters delve more deeply into missing data problems, covariate measurement errors, and censored responses in mixed effects models. Focusing on incomplete data, the book also covers survival and frailty models, joint models of survival and longitudinal data, robust methods for mixed effects models, marginal generalized estimating equation (GEE) models for longitudinal or clustered data, and Bayesian methods for mixed effects models. Background material In the appendix, the author provides background information, such as likelihood theory, the Gibbs sampler, rejection and importance sampling methods, numerical integration methods, optimization methods, bootstrap, and matrix algebra. Failure to properly address missing data, measurement errors, and other issues in statistical analyses can lead to severely biased or misleading results. This book explores the biases that arise when naïve methods are used and shows which approaches should be used to achieve accurate results in longitudinal data analysis.

Accelerating Monte Carlo methods for Bayesian inference in dynamical models

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Publisher : Linköping University Electronic Press
ISBN 13 : 9176857972
Total Pages : 139 pages
Book Rating : 4.1/5 (768 download)

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Book Synopsis Accelerating Monte Carlo methods for Bayesian inference in dynamical models by : Johan Dahlin

Download or read book Accelerating Monte Carlo methods for Bayesian inference in dynamical models written by Johan Dahlin and published by Linköping University Electronic Press. This book was released on 2016-03-22 with total page 139 pages. Available in PDF, EPUB and Kindle. Book excerpt: Making decisions and predictions from noisy observations are two important and challenging problems in many areas of society. Some examples of applications are recommendation systems for online shopping and streaming services, connecting genes with certain diseases and modelling climate change. In this thesis, we make use of Bayesian statistics to construct probabilistic models given prior information and historical data, which can be used for decision support and predictions. The main obstacle with this approach is that it often results in mathematical problems lacking analytical solutions. To cope with this, we make use of statistical simulation algorithms known as Monte Carlo methods to approximate the intractable solution. These methods enjoy well-understood statistical properties but are often computational prohibitive to employ. The main contribution of this thesis is the exploration of different strategies for accelerating inference methods based on sequential Monte Carlo (SMC) and Markov chain Monte Carlo (MCMC). That is, strategies for reducing the computational effort while keeping or improving the accuracy. A major part of the thesis is devoted to proposing such strategies for the MCMC method known as the particle Metropolis-Hastings (PMH) algorithm. We investigate two strategies: (i) introducing estimates of the gradient and Hessian of the target to better tailor the algorithm to the problem and (ii) introducing a positive correlation between the point-wise estimates of the target. Furthermore, we propose an algorithm based on the combination of SMC and Gaussian process optimisation, which can provide reasonable estimates of the posterior but with a significant decrease in computational effort compared with PMH. Moreover, we explore the use of sparseness priors for approximate inference in over-parametrised mixed effects models and autoregressive processes. This can potentially be a practical strategy for inference in the big data era. Finally, we propose a general method for increasing the accuracy of the parameter estimates in non-linear state space models by applying a designed input signal. Borde Riksbanken höja eller sänka reporäntan vid sitt nästa möte för att nå inflationsmålet? Vilka gener är förknippade med en viss sjukdom? Hur kan Netflix och Spotify veta vilka filmer och vilken musik som jag vill lyssna på härnäst? Dessa tre problem är exempel på frågor där statistiska modeller kan vara användbara för att ge hjälp och underlag för beslut. Statistiska modeller kombinerar teoretisk kunskap om exempelvis det svenska ekonomiska systemet med historisk data för att ge prognoser av framtida skeenden. Dessa prognoser kan sedan användas för att utvärdera exempelvis vad som skulle hända med inflationen i Sverige om arbetslösheten sjunker eller hur värdet på mitt pensionssparande förändras när Stockholmsbörsen rasar. Tillämpningar som dessa och många andra gör statistiska modeller viktiga för många delar av samhället. Ett sätt att ta fram statistiska modeller bygger på att kontinuerligt uppdatera en modell allteftersom mer information samlas in. Detta angreppssätt kallas för Bayesiansk statistik och är särskilt användbart när man sedan tidigare har bra insikter i modellen eller tillgång till endast lite historisk data för att bygga modellen. En nackdel med Bayesiansk statistik är att de beräkningar som krävs för att uppdatera modellen med den nya informationen ofta är mycket komplicerade. I sådana situationer kan man istället simulera utfallet från miljontals varianter av modellen och sedan jämföra dessa mot de historiska observationerna som finns till hands. Man kan sedan medelvärdesbilda över de varianter som gav bäst resultat för att på så sätt ta fram en slutlig modell. Det kan därför ibland ta dagar eller veckor för att ta fram en modell. Problemet blir särskilt stort när man använder mer avancerade modeller som skulle kunna ge bättre prognoser men som tar för lång tid för att bygga. I denna avhandling använder vi ett antal olika strategier för att underlätta eller förbättra dessa simuleringar. Vi föreslår exempelvis att ta hänsyn till fler insikter om systemet och därmed minska antalet varianter av modellen som behöver undersökas. Vi kan således redan utesluta vissa modeller eftersom vi har en bra uppfattning om ungefär hur en bra modell ska se ut. Vi kan också förändra simuleringen så att den enklare rör sig mellan olika typer av modeller. På detta sätt utforskas rymden av alla möjliga modeller på ett mer effektivt sätt. Vi föreslår ett antal olika kombinationer och förändringar av befintliga metoder för att snabba upp anpassningen av modellen till observationerna. Vi visar att beräkningstiden i vissa fall kan minska ifrån några dagar till någon timme. Förhoppningsvis kommer detta i framtiden leda till att man i praktiken kan använda mer avancerade modeller som i sin tur resulterar i bättre prognoser och beslut.