Paradoxic Mutations

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Publisher :
ISBN 13 :
Total Pages : 30 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis Paradoxic Mutations by : Margot Lovejoy

Download or read book Paradoxic Mutations written by Margot Lovejoy and published by . This book was released on 1994 with total page 30 pages. Available in PDF, EPUB and Kindle. Book excerpt: The structure of Paradoxic Mutations, though bound by only two staples, consists of an elaborate set of folded pages that open individually to reveal the darker side of virtues such as Unity, Joy, and Freedom. The inverse of Knowledge, for example, is Learned Ignorance. A second set of folded pages deals with the human body, infection, and the implications of technologically-driven medicine. The book is lavishly illustrated throughout with a continuous collage of found material, including anatomical engravings, medical photographs, and images of historical sculptures and other artwork from around the world, dealing mostly with science and the body. Lovejoy's work paints a gruesome but fascinating portrait of our physical relationship to a set of abstract values, commenting on the dangerous potential consequences of our attitudes regarding body and mind.

The Paradox of Evolution

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Publisher : Prometheus Books
ISBN 13 : 1633880729
Total Pages : 250 pages
Book Rating : 4.6/5 (338 download)

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Book Synopsis The Paradox of Evolution by : Stephen Rothman

Download or read book The Paradox of Evolution written by Stephen Rothman and published by Prometheus Books. This book was released on 2015 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: "In [this book], psychologist Stephen Rothman exposes a major, through remarkably amost completely neglected problem with Darwin's theory of evolution. Its two essential elements, natural selection and reproduction, are in important respects contradictory. In considering their relationship, Rothman makes the revolutionary claim that the evolution of life's complex and diverse reproductive mechanisms is not the consequence of natural selection. In so doing, he exposes the deepest question possible about life's nature-- its reason for being. In meticulously detailed but accessible terms he lays out the crux of the paradox and offers an intriguing solution within a naturalistic framework. In an obstensibly purposeless universe, somehow purposeful life has evolved. For all living things there are two overarching purposes: survival and the creation of new life. Natural selection is about the survival of existing life but has no interest in life's future, whether it persists or perishes. By contrast, reproduction is only about the future of life and has no interest in existing life except as a means to an end. Where do these purposes come from? As Rothamn demonstrates, at every level life is wired to react to danger. Counterintuitively, without danger life would neithr have come into being nor evolved. In the same way, death drives the creation of new life and has propelled the evolution of the mechanisms of reproduction. Written with great clarity and informed by deep learning, this elegant, thoughtful work tackles some of the most challening questions raised by the theory of evolution."--Page [4] Cover.

The Molecular Basis of Mutation

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Publisher :
ISBN 13 :
Total Pages : 292 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis The Molecular Basis of Mutation by : John W. Drake

Download or read book The Molecular Basis of Mutation written by John W. Drake and published by . This book was released on 1970 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: Prospects for a molecular description of mutation; Why bacteriophages?; Bacteriophage genetics: first principles; Genetic mapping and the dissection of the gene; Mutation rates; Collecting mutants: procedures and precautions; Mutations in viruses; The taxonomy of mutational lesions; The origin and properties of macrolesions; Transitions; Transversions; Frameshift mutations; Chemical mutagenesis: Radiation mutagenesis; Spontaneous mutation; Mutational heterozygotes; Suppression; Complementation and polarity; Pseudomutation.

Debating Cancer: The Paradox In Cancer Research

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Publisher : World Scientific
ISBN 13 : 9814520861
Total Pages : 463 pages
Book Rating : 4.8/5 (145 download)

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Book Synopsis Debating Cancer: The Paradox In Cancer Research by : Henry H Q Heng

Download or read book Debating Cancer: The Paradox In Cancer Research written by Henry H Q Heng and published by World Scientific. This book was released on 2015-10-08 with total page 463 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer research is at a crossroads. Traditionally, cancer has been thought of as a disease of gene mutation, where the stepwise accumulation of cancer gene mutations is the key, and the identification of common gene mutations has been considered to be essential for diagnosis and treatment. Despite extensive research efforts and accumulated knowledge on cancer genes and pathways, the clinical benefits of this traditional approach have been limited. Recently, cancer genome sequencing has revealed an extensive amount of genetic heterogeneity where the long-expected common mutation drivers have been difficult, if not impossible, to identify. These realities ultimately challenge the conceptual framework of current cancer biology.This book introduces a new concept of genome theory of cancer evolution, in an attempt to unify the field. Many important and representative, but often confusing, questions and paradoxes are critically analyzed. By comparing gene- and genome-based theories, the hidden flaws of many popular viewpoints are addressed. This discussion is intended to initiate a much-needed critical re-evaluation of current cancer research.

Jasper's Basic Mechanisms of the Epilepsies

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Publisher : OUP USA
ISBN 13 : 0199746540
Total Pages : 1258 pages
Book Rating : 4.1/5 (997 download)

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Book Synopsis Jasper's Basic Mechanisms of the Epilepsies by : Jeffrey Noebels

Download or read book Jasper's Basic Mechanisms of the Epilepsies written by Jeffrey Noebels and published by OUP USA. This book was released on 2012-06-29 with total page 1258 pages. Available in PDF, EPUB and Kindle. Book excerpt: Jasper's Basic Mechanisms, Fourth Edition, is the newest most ambitious and now clinically relevant publishing project to build on the four-decade legacy of the Jasper's series. In keeping with the original goal of searching for "a better understanding of the epilepsies and rational methods of prevention and treatment.", the book represents an encyclopedic compendium neurobiological mechanisms of seizures, epileptogenesis, epilepsy genetics and comordid conditions. Of practical importance to the clinician, and new to this edition are disease mechanisms of genetic epilepsies and therapeutic approaches, ranging from novel antiepileptic drug targets to cell and gene therapies.

Paradoxical Life

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Publisher : Yale University Press
ISBN 13 : 0300156375
Total Pages : 271 pages
Book Rating : 4.3/5 (1 download)

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Book Synopsis Paradoxical Life by : Andreas Wagner

Download or read book Paradoxical Life written by Andreas Wagner and published by Yale University Press. This book was released on 2009-09-01 with total page 271 pages. Available in PDF, EPUB and Kindle. Book excerpt: What can a fingernail tell us about the mysteries of creation? In one sense, a nail is merely a hunk of mute matter, yet in another, it's an information superhighway quite literally at our fingertips. Every moment, streams of molecular signals direct our cells to move, flatten, swell, shrink, divide, or die. Andreas Wagner's ambitious new book explores this hidden web of unimaginably complex interactions in every living being. In the process, he unveils a host of paradoxes underpinning our understanding of modern biology, contradictions he considers gatekeepers at the frontiers of knowledge. Though we tend to think of concepts in such mutually exclusive pairs as mind-matter, self-other, and nature-nurture, Wagner argues that these opposing ideas are not actually separate. Indeed, they are as inextricably connected as the two sides of a coin. Through a tour of modern biological marvels, Wagner illustrates how this paradoxical tension has a profound effect on the way we define the world around us. Paradoxical Life is thus not only a unique account of modern biology. It ultimately serves a radical--and optimistic--outlook for humans and the world we help create.

Aneurysms-Osteoarthritis Syndrome

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Publisher : Elsevier
ISBN 13 : 0128027118
Total Pages : 180 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Aneurysms-Osteoarthritis Syndrome by : Denise van der Linde

Download or read book Aneurysms-Osteoarthritis Syndrome written by Denise van der Linde and published by Elsevier. This book was released on 2016-10-03 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aneurysms-Osteoarthritis Syndrome: SMAD3 Gene Mutations is a first-of-its-kind compilation of the genetic discovery, research, and care associated with AOS. With the field of genetically triggered aortopathies growing, this important reference will compile the newest discoveries in this field, allowing cardiologists, cardio-thoracic surgeons, clinical geneticists, vascular surgeons, orthopedic surgeons, and researchers to gain the knowledge they need without having to gather the data from various sources. Coverage includes genotype and phenotype correlations, the functional role of SMAD3, and insights into the role of TGFbeta signaling in aortic disease. The book will increase knowledge about AOS, providing awareness and better patient care for this aggressive disease. - Covers Aneurysms-Osteoarthritis Syndrome, from genetic discovery to patient care - Contains clinical management guidance on optimal cardiovascular treatments and surgery - Explains the autosomal dominant syndromes caused by mutations in the SMAD3 gene - Identifies the key features of this syndrome, including arterial aneurysms and tortuosity, early onset arthritis, and mild craniofacial features

Genetics of Adaptation

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Publisher : Springer Science & Business Media
ISBN 13 : 1402038364
Total Pages : 207 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Genetics of Adaptation by : Rodney Mauricio

Download or read book Genetics of Adaptation written by Rodney Mauricio and published by Springer Science & Business Media. This book was released on 2005-07-20 with total page 207 pages. Available in PDF, EPUB and Kindle. Book excerpt: An enduring controversy in evolutionary biology is the genetic basis of adaptation. Darwin emphasized "many slight differences" as the ultimate source of variation to be acted upon by natural selection. In the early 1900’s, this view was opposed by "Mendelian geneticists", who emphasized the importance of "macromutations" in evolution. The Modern Synthesis resolved this controversy, concluding that mutations in genes of very small effect were responsible for adaptive evolution. A decade ago, Allen Orr and Jerry Coyne reexamined the evidence for this neo-Darwinian view and found that both the theoretical and empirical basis for it were weak. Orr and Coyne encouraged evolutionary biologists to reexamine this neglected question: what is the genetic basis of adaptive evolution? In this volume, a new generation of biologists have taken up this challenge. Using advances in both molecular genetic and statistical techniques, evolutionary geneticists have made considerable progress in this emerging field. In this volume, a diversity of examples from plant and animal studies provides valuable information for those interested in the genetics and evolution of complex traits.

The Paradoxical Situation in Carcinogenesis

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Publisher : Cambridge Scholars Publishing
ISBN 13 : 1527542653
Total Pages : 166 pages
Book Rating : 4.5/5 (275 download)

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Book Synopsis The Paradoxical Situation in Carcinogenesis by : George D. K. Gogichadze

Download or read book The Paradoxical Situation in Carcinogenesis written by George D. K. Gogichadze and published by Cambridge Scholars Publishing. This book was released on 2019-11-01 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is dedicated to the ethical problems related to carcinogenesis. It discusses the karyogamic theory in a new light, using new arguments, and considers the prospects of cancer prevention and treatment. The current stage of scientific development fails to answer such questions as: What is a cancer cell? What is its essence? In the opinion of most cancer researchers, the genetic apparatus of the target cell should be responsible for the conversion of a tumour cell into a normal one. This book, however, highlights the often-disregarded role of non-DNA cellular elements in carcinogenesis. It also investigates the loss of contact inhibition of cancer cells, the cellular mechanism of malignization in the case of hemolytic anemia, and the high oncogenic risk of low and medium doses of carcinogens, as well as the common trigger mechanism of action of diametrically different carcinogens on target cells.

Chaos, Information Processing And Paradoxical Games: The Legacy Of John S Nicolis

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Publisher : World Scientific
ISBN 13 : 9814602140
Total Pages : 474 pages
Book Rating : 4.8/5 (146 download)

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Book Synopsis Chaos, Information Processing And Paradoxical Games: The Legacy Of John S Nicolis by : Gregoire Nicolis

Download or read book Chaos, Information Processing And Paradoxical Games: The Legacy Of John S Nicolis written by Gregoire Nicolis and published by World Scientific. This book was released on 2014-12-30 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a self-contained survey of the mechanisms presiding information processing and communication. The main thesis is that chaos and complexity are the basic ingredients allowing systems composed of interesting subunits to generate and process information and communicate in a meaningful way. Emphasis is placed on communication in the form of games and on the related issue of decision making under conditions of uncertainty. Biological, cognitive, physical, engineering and societal systems are approached from a unifying point of view, both analytically and by numerical simulation, using the methods of nonlinear dynamics and probability theory. Epistemological issues in connection with incompleteness and self-reference are also addressed.

Mutants and Mystics

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Publisher : University of Chicago Press
ISBN 13 : 0226453839
Total Pages : 392 pages
Book Rating : 4.2/5 (264 download)

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Book Synopsis Mutants and Mystics by : Jeffrey J. Kripal

Download or read book Mutants and Mystics written by Jeffrey J. Kripal and published by University of Chicago Press. This book was released on 2011-11-15 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Account of how comic book heroes have helped their creators and fans alike explore and express a wealth of paranormal experiences ignored by mainstream science. Delving deeply into the work of major figures in the field - from Jack Kirby's cosmic superhero sagas and Philip K. Dick's futuristic head-trips to Alan Moore's sex magic and Whitley Strieber's communion with visitors - Kripal shows how creators turned to science fiction to convey the reality of the inexplicable and the paranormal they experienced in their lives. Expanded consciousness found its language in the metaphors of sci-fi - incredible powers, unprecedented mutations, time-loops and vast intergalactic intelligences - and the deeper influences of mythology and religion that these in turn drew from ; the wildly creative work that followed caught the imaginations of millions. Moving deftly from Cold War science and Fredric Wertham's anticomics crusade to gnostic revelation and alien abduction, Kripal spins out a hidden history of American culture, rich with mythical themes and shot through with an awareness that there are other realities far beyond our everyday understanding."--Jacket.

Neurogenetics, Part II

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Publisher : Elsevier
ISBN 13 : 0444640770
Total Pages : 480 pages
Book Rating : 4.4/5 (446 download)

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Book Synopsis Neurogenetics, Part II by :

Download or read book Neurogenetics, Part II written by and published by Elsevier. This book was released on 2018-01-29 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurogenetics, Part II, Volume 148, the latest release in the Handbook of Clinical Neurology, provides the latest information on the genetic methodologies that are having a significant impact on the study of neurological and psychiatric disorders. Using genetic science, researchers have identified over 200 genes that cause or contribute to neurological disorders. Still an evolving field of study, defining the relationship between genes and neurological and psychiatric disorders is expected to dramatically grow in scope. Part II builds on the foundation of Part I, expanding the coverage to dementias, paroxysmal disorders, neuromuscular disorders, white matter and demyelination diseases, cerebrovascular diseases, adult psychiatric disorders and cancer and phacomatoses. - Contains comprehensive coverage of neurogenetics - Details the latest science and its impact on our understanding of neurological, psychiatric disorders - Presents a focused reference for clinical practitioners and the neuroscience/neurogenetics research community

Epileptic Syndromes in Infancy, Childhood and Adolescence - 5th edition

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Publisher : John Libbey Eurotext
ISBN 13 : 2742008292
Total Pages : 682 pages
Book Rating : 4.7/5 (42 download)

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Book Synopsis Epileptic Syndromes in Infancy, Childhood and Adolescence - 5th edition by : Bureau Michelle

Download or read book Epileptic Syndromes in Infancy, Childhood and Adolescence - 5th edition written by Bureau Michelle and published by John Libbey Eurotext. This book was released on 2012-11-12 with total page 682 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ultimate reference book : the 5th updated edition of the famous “blue guide”. Incluided : A DVD with new sequences completes each chapter! Epileptology changes. The syndromic approach is completed by an etiological approach, based on the major advances in genetics and functional genetics. New entities have found their place, and a purely descriptive, “electroclinical” approach is no longer adapted in many circumstances. The 5th edition of the Blue Guide includes the most recent advances. It was necessary to justify the physiological, epidemiologic, genetic and therapeutic approaches and to consider them in the light of the new classification efforts, which are still in the making. Nevertheless, the description of epileptic syndromes, both classical and recent, remains at the core of this book.

AACR 2017 Proceedings: Abstracts 3063-5947

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Publisher : CTI Meeting Technology
ISBN 13 :
Total Pages : 2975 pages
Book Rating : 4./5 ( download)

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Book Synopsis AACR 2017 Proceedings: Abstracts 3063-5947 by : American Association for Cancer Research

Download or read book AACR 2017 Proceedings: Abstracts 3063-5947 written by American Association for Cancer Research and published by CTI Meeting Technology. This book was released on 2017-03-13 with total page 2975 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Ontological Catastrophe: Žižek and the Paradoxical Metaphysics of German Idealism

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Publisher : DigiCat
ISBN 13 :
Total Pages : 333 pages
Book Rating : 4.8/5 (596 download)

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Book Synopsis Ontological Catastrophe: Žižek and the Paradoxical Metaphysics of German Idealism by : Joseph Carew

Download or read book Ontological Catastrophe: Žižek and the Paradoxical Metaphysics of German Idealism written by Joseph Carew and published by DigiCat. This book was released on 2023-12-23 with total page 333 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is an original investigation into Slavoj Žižek's return to German Idealism in the wake of Lacanian psychoanalysis. As is well known, Žižek creates productive friction between these traditions by isolating their mutually compatible notions of the death drive, paving the way for Žižek's highly original model of the subject. Joseph Carew systematizes the stark metaphysical consequences of Žižek's account. If the emergence of the Symbolic out of the Real marks the advent of a completely self-enclosed structural system, then we must posit the absolute as a fragile not-all wrought by negativity and antagonism.

Williams Textbook of Endocrinology E-Book

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Publisher : Elsevier Health Sciences
ISBN 13 : 0323711545
Total Pages : 2239 pages
Book Rating : 4.3/5 (237 download)

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Book Synopsis Williams Textbook of Endocrinology E-Book by : Shlomo Melmed

Download or read book Williams Textbook of Endocrinology E-Book written by Shlomo Melmed and published by Elsevier Health Sciences. This book was released on 2019-11-14 with total page 2239 pages. Available in PDF, EPUB and Kindle. Book excerpt: Expertly bridging the gap between basic science and clinical information, Williams Textbook of Endocrinology, 14th Edition, brings together an outstanding collection of world-renowned authors to provide authoritative discussions of the full spectrum of adult and pediatric endocrine system disorders. New chapters and significant revisions throughout keep you up to date with recent advances in medications, therapies, clinical trials, and more. This essential reference is a must-have resource for endocrinologists, endocrine surgeons, gynecologists, internists, pediatricians, and other clinicians who need current, comprehensive coverage of this multifaceted field. Up to date with recent advances in medications, therapies, and clinical trials. Provides state-of-the-art coverage of diabetes, metabolic syndrome, metabolic bones disorders, obesity, thyroid disease, testicular disorders, newly defined adrenal disorders and much more - all designed to help you provide optimal care to every patient. Contains new chapters on Global Burden of Endocrine Disease, Navigation of Endocrine Guidelines, and Transgender Endocrinology. Includes significant updates to the Diabetes section, including a new chapter on Physiology of Insulin Secretion and greater coverage of Type 2 Diabetes. Presents current information in a highly illustrated, user-friendly format for quick reference.

Cassidy and Allanson's Management of Genetic Syndromes

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Publisher : John Wiley & Sons
ISBN 13 : 1119432677
Total Pages : 1104 pages
Book Rating : 4.1/5 (194 download)

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Book Synopsis Cassidy and Allanson's Management of Genetic Syndromes by : John C. Carey

Download or read book Cassidy and Allanson's Management of Genetic Syndromes written by John C. Carey and published by John Wiley & Sons. This book was released on 2021-01-27 with total page 1104 pages. Available in PDF, EPUB and Kindle. Book excerpt: MANAGEMENT OF GENETIC SYNDROMES THE MOST RECENT UPDATE TO ONE OF THE MOST ESSENTIAL REFERENCES ON MEDICAL GENETICS Cassidy and Allanson’s Management of Genetic Syndromes, Fourth Edition is the latest version of a classic text in medical genetics. With newly covered disorders and cutting-edge, up-to-date information, this resource remains the most crucial reference on the management of genetic syndromes in the field of medical genetics for students, clinicians, caregivers, and researchers. The fourth edition includes current information on the identification of genetic syndromes (including newly developed diagnostic criteria), the genetic basis (including diagnostic testing), and the routine care and management for more than 60 genetic disorders. Written by experts, each chapter includes sections on: Incidence Diagnostic criteria Etiology, pathogenesis and genetics Diagnostic testing Differential diagnosis Manifestations and Management (by system) The book focuses on genetic syndromes, primarily those involving developmental disabilities and congenital defects. The chapter sections dealing with Manifestations and Management represents the centerpiece of each entry and is unmatched by other genetic syndrome references. Management of Genetic Syndromes is perfect for medical geneticists, genetic counselors, primary care physicians and all healthcare professionals seeking to stay current on the routine care and management of individuals with genetic disorders.