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Download or read book Papers Presented at the 239th ACS National Meeting in San Francisco, CA March 21-25, 2010 written by and published by . This book was released on 2010 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Thomas G. Davies
Publisher : Springer Science & Business Media
ISBN 13 : 3642275400
Total Pages : 235 pages
Book Rating : 4.6/5 (422 download)
Download or read book Fragment-Based Drug Discovery and X-Ray Crystallography written by Thomas G. Davies and published by Springer Science & Business Media. This book was released on 2012-01-24 with total page 235 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction to Fragment-Based Drug Discovery, by Daniel A. Erlanson Fragment Screening Using X-Ray Crystallography, by Thomas G. Davies and Ian J. Tickle Hsp90 Inhibitors and Drugs from Fragment and Virtual Screening, by Stephen Roughley, Lisa Wright, Paul Brough, Andrew Massey and Roderick E. Hubbard Combining NMR and X-ray Crystallography in Fragment-Based Drug Discovery: Discovery of Highly Potent and Selective BACE-1 Inhibitors, by Daniel F. Wyss, Yu-Sen Wang, Hugh L. Eaton, Corey Strickland, Johannes H. Voigt, Zhaoning Zhu and Andrew W. Stamford Combining Biophysical Screening and X-Ray Crystallography for Fragment-Based Drug Discovery, by Michael Hennig, Armin Ruf and Walter Huber Targeting Protein–Protein Interactions and Fragment-Based Drug Discovery, by Eugene Valkov, Tim Sharpe, May Marsh, Sandra Greive and Marko Hyvönen Fragment Screening and HIV Therapeutics, by Joseph D. Bauman, Disha Patel and Eddy Arnold Fragment-Based Approaches and Computer-Aided Drug Discovery, by Didier Rognan
Author : John E. Macor
Publisher : Academic Press
ISBN 13 : 012396492X
Total Pages : 686 pages
Book Rating : 4.1/5 (239 download)
Download or read book Annual Reports in Medicinal Chemistry written by John E. Macor and published by Academic Press. This book was released on 2012-10-08 with total page 686 pages. Available in PDF, EPUB and Kindle. Book excerpt: Annual Reports in Medicinal chemistry continues to be the premier source for reviews of seminal aspects of medicinal chemistry, providing timely and critical reviews of the important topics in medicinal chemistry today.
Author : Chaudhery Mustansar Hussain
Publisher : Royal Society of Chemistry
ISBN 13 : 178262144X
Total Pages : 560 pages
Book Rating : 4.7/5 (826 download)
Download or read book Advanced Environmental Analysis written by Chaudhery Mustansar Hussain and published by Royal Society of Chemistry. This book was released on 2016-11-14 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: Environmental analysis techniques have advanced due to the use of nanotechnologies in improving the detection sensitivity and miniaturization of the devices in analytical procedures. These allow for developments such as increases in analyte concentration, the removal of interfering species and improvements in the detection limits. Bridging a gap in the literature, this book uniquely brings together state-of-the-art research in the applications of novel nanomaterials to each of the classical components of environmental analysis, namely sample preparation and extraction, separation and identification by spectroscopic techniques. Special attention is paid to those approaches that are considered greener and reduce the cost of the analysis process both in terms of chemicals and time consumption. Advanced undergraduates, graduates and researchers at the forefront of environmental science and engineering will find this book a good source of information. It will also help regulators, decision makers, surveillance agencies and the organizations assessing the impact of pollutants on the environment.
Author :
Publisher : Elsevier
ISBN 13 : 0128032014
Total Pages : 4609 pages
Book Rating : 4.1/5 (28 download)
Download or read book Comprehensive Medicinal Chemistry III written by and published by Elsevier. This book was released on 2017-06-03 with total page 4609 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive Medicinal Chemistry III, Eight Volume Set provides a contemporary and forward-looking critical analysis and summary of recent developments, emerging trends, and recently identified new areas where medicinal chemistry is having an impact. The discipline of medicinal chemistry continues to evolve as it adapts to new opportunities and strives to solve new challenges. These include drug targeting, biomolecular therapeutics, development of chemical biology tools, data collection and analysis, in silico models as predictors for biological properties, identification and validation of new targets, approaches to quantify target engagement, new methods for synthesis of drug candidates such as green chemistry, development of novel scaffolds for drug discovery, and the role of regulatory agencies in drug discovery. Reviews the strategies, technologies, principles, and applications of modern medicinal chemistry Provides a global and current perspective of today's drug discovery process and discusses the major therapeutic classes and targets Includes a unique collection of case studies and personal assays reviewing the discovery and development of key drugs
Author : J. Dubessy
Publisher : The Mineralogical Society of Great Britain and Ireland
ISBN 13 : 0903056313
Total Pages : 519 pages
Book Rating : 4.9/5 (3 download)
Download or read book Raman Spectroscopy Applied to Earth Sciences and Cultural Heritage written by J. Dubessy and published by The Mineralogical Society of Great Britain and Ireland. This book was released on 2012-11-20 with total page 519 pages. Available in PDF, EPUB and Kindle. Book excerpt: Spectroscopic methods such as Raman are used to investigate the structure and dynamics of matter. They are essential for the study of the different types of mineral or organic materials produced at the Earths surface or interior. As a result of technological improvements in gratings, detectors, filters and personal computers in the last decade, many micro-Raman spectrometers have become plug-and-play instruments, very easy to use and available at a lower cost than the early Raman microprobes. Thus, many laboratories in Earth Sciences and Cultural Heritage are equipped with these new spectrometers. Commercial, portable Raman spectrometers working in the field have also contributed to the spread of Raman spectroscopy. Poor levels of education in terms of Raman spectroscopy in undergraduate courses in Earth Sciences make it difficult for individuals to obtain information of the highest quality relevant to Earth sciences and Cultural Heritage. This volume is, therefore, timely. Four main topics are addressed: Theory; Methodology, including the instrumentation; Experimental aspects; and Application.
Author : Pedro J. Pérez
Publisher : Springer Science & Business Media
ISBN 13 : 9048136989
Total Pages : 277 pages
Book Rating : 4.0/5 (481 download)
Download or read book Alkane C-H Activation by Single-Site Metal Catalysis written by Pedro J. Pérez and published by Springer Science & Business Media. This book was released on 2012-09-15 with total page 277 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past decade, much research effort has been devoted to the design and synthesis of new reagents and catalysts that can influence carbon-hydrogen bond activation, mainly because of the prospect that C−H activation could enable the conversion of cheap and abundant alkanes into valuable functionalized organic compounds. Alkane C-H Activation by Single-Site Metal Catalysis presents the current state-of-the-art development in the catalytic systems for the catalytic trans-formations of alkanes under homogeneous conditions. Chapter 1 offers a comprehensive summary of the main discoveries realized so far. Chapter 2 reviews the so-called electrophilic activation, initiated by Shulpín in the late 60s, and the base for the Catalytica system. Chapter 3 examines the catalytic borylation of alkanes, discovered by Hartwig, whereas chapter 4 provides an updated vision of the alkane dehydrogenation reaction. Chapter 5 covers the oxygenation of C-H bonds, a field of enormous interest with bioinorganic im-plications, and finally chapter 6 presents the functionalization of alkane C-H bonds by carbene or nitrene insertion. The history of C-H bond activation, and the current research described in this book, highlight the current research and present the reader with an outlook of this field which continues to be explored by an increasingly visionary and enthusiastic group of organic, organometallic, biological and physical chemists.
Author : Gertz I. Likhtenshtein
Publisher : John Wiley & Sons
ISBN 13 : 3527647686
Total Pages : 425 pages
Book Rating : 4.5/5 (276 download)
Download or read book Solar Energy Conversion written by Gertz I. Likhtenshtein and published by John Wiley & Sons. This book was released on 2012-02-13 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt: Finally filling a gap in the literature for a text that also adopts the chemist's view of this hot topic, Professor Likhtenshtein, an experienced author and internationally renowned scientist, considers different physical and engineering aspects in solar energy conversion. From theory to real-life systems, he shows exactly which chemical reactions take place when converting light energy, providing an overview of the chemical perspective from fundamentals to molecular harvesting systems and solar cells. This essential guide will thus help researchers in academia and industry better understand solar energy conversion, and so ultimately help this promising, multibillion dollar fi eld to expand. From the contents: * Electron Transfer Theories * Principle Stages of Photosynthetic Light Energy Conversion * Photochemical Systems of Light Energy Conversion * Redox Processes on Surface of Semiconductors and Metals * Dye-Sensitized Solar Cells * Photocatalytic Reduction and Oxidation of Water
Author : Stanisław Grundas
Publisher : BoD – Books on Demand
ISBN 13 : 9533075228
Total Pages : 770 pages
Book Rating : 4.5/5 (33 download)
Download or read book Advances in Induction and Microwave Heating of Mineral and Organic Materials written by Stanisław Grundas and published by BoD – Books on Demand. This book was released on 2011-02-14 with total page 770 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book offers comprehensive coverage of the broad range of scientific knowledge in the fields of advances in induction and microwave heating of mineral and organic materials. Beginning with industry application in many areas of practical application to mineral materials and ending with raw materials of agriculture origin the authors, specialists in different scientific area, present their results in the two sections: Section 1-Induction and Microwave Heating of Mineral Materials, and Section 2-Microwave Heating of Organic Materials.
Author : Christopher Barner-Kowollik
Publisher : John Wiley & Sons
ISBN 13 : 3527641831
Total Pages : 501 pages
Book Rating : 4.5/5 (276 download)
Download or read book Mass Spectrometry in Polymer Chemistry written by Christopher Barner-Kowollik and published by John Wiley & Sons. This book was released on 2012-01-27 with total page 501 pages. Available in PDF, EPUB and Kindle. Book excerpt: Combining an up-to-date insight into mass-spectrometric polymer analysis beyond MALDI with application details of the instrumentation, this is a balanced and thorough presentation of the most important and widely used mass-spectrometric methods. Written by the world's most proficient experts in the field, the book focuses on the latest developments, covering such technologies and applications as ionization protocols, tandem and liquid chromatography mass spectrometry, gas-phase ion-separation techniques and automated data processing. Chapters on sample preparation, polymer degradation and the usage of mass-spectrometric tools on an industrial scale round off the book. As a result, both entrants to the field and experienced researchers are able to choose the appropriate methods and instrumentations -- and to assess their respective strengths and limitations -- for the characterization of polymer compounds.
Author : Boris I. Kharisov
Publisher : CRC Press
ISBN 13 : 1439853436
Total Pages : 867 pages
Book Rating : 4.4/5 (398 download)
Download or read book Handbook of Less-Common Nanostructures written by Boris I. Kharisov and published by CRC Press. This book was released on 2012-03-19 with total page 867 pages. Available in PDF, EPUB and Kindle. Book excerpt: As nanotechnology has developed over the last two decades, some nanostructures, such as nanotubes, nanowires, and nanoparticles, have become very popular. However, recent research has led to the discovery of other, less-common nanoforms, which often serve as building blocks for more complex structures. In an effort to organize the field, the Handbook of Less-Common Nanostructures presents an informal classification based mainly on the less-common nanostructures. A small nanotechnological encyclopedia, this book: Describes a range of little-known nanostructures Offers a unifying vision of the synthesis of nanostructures and the generalization of rare nanoforms Includes a CD-ROM with color versions of more than 100 nanostructures Explores the fabrication of rare nanostructures, including modern physical, chemical, and biological synthesis techniques The Handbook of Less-Common Nanostructures discusses a classification system not directly related to the dimensionality and chemical composition of nanostructure-forming compounds or composite. Instead, it is based mainly on the less-common nanostructures. Possessing unusual shapes and high surface areas, these structures are potentially very useful for catalytic, medical, electronic, and many other applications.
Author : Jun-Ping Xu
Publisher : CRC Press
ISBN 13 : 1351260987
Total Pages : 452 pages
Book Rating : 4.3/5 (512 download)
Download or read book Natural Substances for Cancer Prevention written by Jun-Ping Xu and published by CRC Press. This book was released on 2018-02-01 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural Substances for Cancer Prevention explores in detail how numerous investigations in chemical biology and molecular biology have established strong scientific evidence demonstrating how the properties of naturally occurring bioactive chemicals hamper all stages of cancers (from initiation to metastasis). Accordingly, important goals for cancer prevention are the modification of our dietary habits and an increase in the intake of more anticancer-related natural substances. More significantly, the bioactive chemicals presented in the functional foods should be readily available, inexpensive, non-toxic, and nutritional.
Author : Nesrin Horzum
Publisher : Walter de Gruyter GmbH & Co KG
ISBN 13 : 3110588633
Total Pages : 405 pages
Book Rating : 4.1/5 (15 download)
Download or read book Green Electrospinning written by Nesrin Horzum and published by Walter de Gruyter GmbH & Co KG. This book was released on 2019-07-22 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: The last two decades have seen electrospinning of nanofibers performed mainly from solutions of toxic organic solvents. The increase in demand for scaling up electrospinning in recent years therefore requires an environmentally friendly process free of organic solvents. This book addresses techniques for clean and safe electrospinning in the fabrication of green nanofibers and their potential applications.
Author : Tomas Torres
Publisher : John Wiley & Sons
ISBN 13 : 1118354362
Total Pages : 636 pages
Book Rating : 4.1/5 (183 download)
Download or read book Organic Nanomaterials written by Tomas Torres and published by John Wiley & Sons. This book was released on 2013-08-05 with total page 636 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discover a new generation of organic nanomaterials and their applications Recent developments in nanoscience and nanotechnology have given rise to a new generation of functional organic nanomaterials with controlled morphology and well-defined properties, which enable a broad range of useful applications. This book explores some of the most important of these organic nanomaterials, describing how they are synthesized and characterized. Moreover, the book explains how researchers have incorporated organic nanomaterials into devices for real-world applications. Featuring contributions from an international team of leading nanoscientists, Organic Nanomaterials is divided into five parts: Part One introduces the fundamentals of nanomaterials and self-assembled nanostructures Part Two examines carbon nanostructures from fullerenes to carbon nanotubes to graphene reporting on properties, theoretical studies, and applications Part Three investigates key aspects of some inorganic materials, self-assembled monolayers, organic field effect transistors, and molecular self-assembly at solid surfaces Part Four explores topics that involve both biological aspects and nanomaterials such as biofunctionalized surfaces Part Five offers detailed examples of how organic nanomaterials enhance sensors and molecular photovoltaics Most of the chapters end with a summary highlighting the key points. References at the end of each chapter guide readers to the growing body of original research reports and reviews in the field. Reflecting the interdisciplinary nature of organic nanomaterials, this book is recommended for researchers in chemistry, physics, materials science, polymer science, and chemical and materials engineering. All readers will learn the principles of synthesizing and characterizing new organic nanomaterials in order to support a broad range of exciting new applications.
Author : James F. Carter
Publisher : CRC Press
ISBN 13 : 1351647687
Total Pages : 503 pages
Book Rating : 4.3/5 (516 download)
Download or read book Food Forensics written by James F. Carter and published by CRC Press. This book was released on 2017-07-28 with total page 503 pages. Available in PDF, EPUB and Kindle. Book excerpt: Food forensics is a multi-disciplinary science involving advanced analytical techniques, plant and animal metabolism, and sophisticated data interpretation tools. This book explains how plants, and in turn animals eating those plants, assimilate stable isotopes and trace elements from their environments. It provides extensive reviews of the use of stable isotope and trace element measurements for the authentication of major food groups and how these can be used to detect fraudsters. The book emphasises the use of correct methods for sample preparation and measurement so that data can be compared to existing datasets, with a dedicated chapter discussing interpretations.
Author : Peter Jeschke
Publisher : John Wiley & Sons
ISBN 13 : 3527655921
Total Pages : 429 pages
Book Rating : 4.5/5 (276 download)
Download or read book Modern Methods in Crop Protection Research written by Peter Jeschke and published by John Wiley & Sons. This book was released on 2013-02-05 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook and ready reference highlights a couple of basic aspects of recently developed new methods in modern crop protection research, authored by renowned experts from major agrochemical companies. Organized into four major parts that trace the key phases of the compound development process, the first section addresses compound design, while the second covers newly developed methods for the identification of the mode of action of agrochemical compounds. The third part describes methods used in improving the bioavailability of compounds, and the final section looks at modern methods for risk assessment. As a result, the agrochemical developer will find here a valuable toolbox of advanced methods, complete with first-hand practical advice and copious examples from current industrial practice.
Author : Se-Kwon Kim
Publisher : CRC Press
ISBN 13 : 1439892296
Total Pages : 457 pages
Book Rating : 4.4/5 (398 download)
Download or read book Marine Pharmacognosy written by Se-Kwon Kim and published by CRC Press. This book was released on 2012-12-06 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diverse and abundant, marine-derived bioactive compounds offer a plethora of pharmacologically active agents with the potential to produce valuable therapeutic entities. Marine-derived organisms, including some macroalgae, microalgae, blue-green algae, invertebrates, and vertebrates—valued in traditional Chinese medicine since ancient times—are now recognized as rich sources of pharmaceutically active compounds. These factors, coupled with the growing need for novel bioactives for the treatment of severe human diseases such as cancer, diabetes, microbial infections, and inflammatory processes, has brought marine pharmaceuticals to the forefront of pharmacology. Marine Pharmacognosy: Trends and Applications provides a comprehensive account of marine-derived bioactive pharmaceuticals and their potential health benefits, including antioxidant, anticancer, antiviral, anticoagulant, antidiabetic, antiallergy, anti-inflammatory, antihypertensive, antibacterial, and radioprotective activities. Moreover, it discusses the sources, isolation and purification, chemistry, functionality interactions, applications, and industrial features of a variety of marine-derived pharmaceuticals. Marine pharmacognosy is a dynamic field that has been systematically investigated over the last 50 years, and the number of publications and patents are increasing every year. Bringing together a global team of experts, Marine Pharmacognosy: Trends and Applications reviews current research on marine-derived bioactive compounds and provides insight into future research on their potential as pharmacologically active agents.
