Ovarian Cancer In Elderly Patients

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Ovarian Cancer in Elderly Patients

Author : Gilles Freyer
Publisher : Springer
ISBN 13 : 3319235885
Total Pages : 106 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis Ovarian Cancer in Elderly Patients by : Gilles Freyer

Download or read book Ovarian Cancer in Elderly Patients written by Gilles Freyer and published by Springer. This book was released on 2015-11-20 with total page 106 pages. Available in PDF, EPUB and Kindle. Book excerpt: This practical book provides up-to-date information on the particular features of ovarian cancer in older women and the best management approach. The full range of relevant topics is covered. Guidance is provided on geriatric assessment, screening, pathology, diagnosis, and follow-up. The various treatment options are carefully explained, covering surgical approaches, chemotherapy as a first-line strategy, the use of anti-angiogenic agents, and treatment of relapse. The cognitive problems that may arise in elderly women during and after treatment of ovarian cancer are documented, with advice on response. Guidance is also provided on the design of clinical trials, and current directions in biological research are reviewed. This book will be of value to both practitioners and researchers with an interest in ovarian cancer and the elderly.

Cancer and Aging

Author : M. Extermann
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318023078
Total Pages : 179 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis Cancer and Aging by : M. Extermann

Download or read book Cancer and Aging written by M. Extermann and published by Karger Medical and Scientific Publishers. This book was released on 2013-01-18 with total page 179 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer is clearly an age-related disease. Recent research in both aging and cancer has demonstrated the complex interaction between the two phenomena. This affects a wide spectrum of research and practice, anywhere from basic research to health care organization. Core examples of these close associations are addressed in this book. Starting with basic research, the first chapters cover cancer development, mTOR inhibition, senescent cells altering the tumor microenvironment, and immune senescence affecting cancer vaccine response. Taking into account the multidisciplinarity of geriatric oncology, several chapters focus on geriatric and oncologic aspects in patient assessment, treatment options, nursing and exercise programs. The book is rounded off by a discussion on the impact of the metabolic syndrome illustrating the interactions between comorbidity and cancer and a chapter on frailty.This book provides the reader with insights that will hopefully foster his or her reflection in their own research and practice to further the development of this most exciting field. Given the aging of the population worldwide and the high prevalence of cancer, it is essential reading not only for oncologists and geriatricians but for all health practitioners.

Ovarian Cancer Treatment in the Elderly

Author : Charalampos Theofanakis
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (116 download)

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Book Synopsis Ovarian Cancer Treatment in the Elderly by : Charalampos Theofanakis

Download or read book Ovarian Cancer Treatment in the Elderly written by Charalampos Theofanakis and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Background. Treatment of elderly patients with neoplasia is challenging due to the frailty of the patients, existing comorbidities and increased number of concomitant medications1. In addition, elderly patients are usually underrepresented in clinical trials2. Age is a known prognostic factor in ovarian cancer but optimal treatment of elderly patients has not been determined3. We undertook a retrospective analysis to determine clinical practice in advanced stage ovarian cancer patients older than 75 years of age.Methodology. Medical records of women with high grade serous and endometrial ovarian cancer, stage III and IV, treated at Alexandra Hospital from 2011 to 2016 were retrospectively identified. Clinicopathological data, treatment and survival data were analyzed. Kaplan-Meier Survival curves were generated using IBM SPSS version 20; survival differences were estimated using the long-rank test. Results. In total, 158 patients were identified with a median age of 61.1 years. Among them 20 (12.7%) were older than 75 years of age at diagnosis (range 75.03- 92.72 years). First line Progression Free Survival (PFS) and Overall Survival (OS) were statistically significant worse in elderly patients in comparison to the younger ones (mPFS 13.4 months vs 21.9 months, P

Cancer in the Elderly

Author : Carrie P. Hunter
Publisher : CRC Press
ISBN 13 : 0824746457
Total Pages : 591 pages
Book Rating : 4.8/5 (247 download)

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Book Synopsis Cancer in the Elderly by : Carrie P. Hunter

Download or read book Cancer in the Elderly written by Carrie P. Hunter and published by CRC Press. This book was released on 2000-03-01 with total page 591 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents comprehensive assessment and up-to-date discussion of the epidemiology, prevention, and treatment of cancer in the elderly, highlighting the growing demands of the disease, its biology, individual susceptibility, the impact of state-of-the-art and emerging therapies on reducing morbidity, and decision making processes. Describ

Management of Gynecological Cancers in Older Women

Author : Stuart M. Lichtman
Publisher : Springer Science & Business Media
ISBN 13 : 1447146050
Total Pages : 418 pages
Book Rating : 4.4/5 (471 download)

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Book Synopsis Management of Gynecological Cancers in Older Women by : Stuart M. Lichtman

Download or read book Management of Gynecological Cancers in Older Women written by Stuart M. Lichtman and published by Springer Science & Business Media. This book was released on 2013-01-11 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book aims to provide an up-to-date review of the literature in each of the major areas relating to the management of older gynecological cancer patients, and makes recommendations for best practice and future research. The authors come from a broad geographic spread including the UK, mainland Europe and North America to ensure a worldwide relevance.

Clinical Gynecology

Author : Eric J. Bieber
Publisher : Cambridge University Press
ISBN 13 : 1107040396
Total Pages : 1127 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis Clinical Gynecology by : Eric J. Bieber

Download or read book Clinical Gynecology written by Eric J. Bieber and published by Cambridge University Press. This book was released on 2015-04-23 with total page 1127 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written with the busy practice in mind, this book delivers clinically focused, evidence-based gynecology guidance in a quick-reference format. It explores etiology, screening, tests, diagnosis, and treatment for a full range of gynecologic health issues. The coverage includes the full range of gynecologic malignancies, reproductive endocrinology and infertility, infectious diseases, urogynecologic problems, gynecologic concerns in children and adolescents, and surgical interventions including minimally invasive surgical procedures. Information is easy to find and absorb owing to the extensive use of full-color diagrams, algorithms, and illustrations. The new edition has been expanded to include aspects of gynecology important in international and resource-poor settings.

ToleRability of BevacizUmab in Elderly Ovarian Cancer Patients (TURBO Study): a Case-control Study of a Real-life Experience

Author : giulia amadio
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (116 download)

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Book Synopsis ToleRability of BevacizUmab in Elderly Ovarian Cancer Patients (TURBO Study): a Case-control Study of a Real-life Experience by : giulia amadio

Download or read book ToleRability of BevacizUmab in Elderly Ovarian Cancer Patients (TURBO Study): a Case-control Study of a Real-life Experience written by giulia amadio and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Objective. Bevacizumab maintenance following platinum-based chemotherapy is an effective treatment for epithelial ovarian cancer (EOC), both in primary and recurrent disease. Our aim was to identify criteria to select elderly patients who can safely benefit from bevacizumab addition.Methods. This is a case-control study on patients with primary or recurrent EOC who received platinum-based chemotherapy plus bevacizumab, between January 2015 - December 2016. Patient characteristics, treatment details and adverse events were reviewed and analyzed in two setting: younger (65 years, group 1) and elderly (65 years, group 2). A binary logistic model was applied to correlate clinical variables and severe (grade u22653) toxicity risk. Results. Overall, 283 patients with EOC were included, with 72 (25.4%) older patients compared with 211 (74.6%) younger women. Bevacizumab had been administered to 234 patients (82.7%) as first-line treatment and in 49 (17.3%) with recurrent disease. At diagnosis, elderly patients presented with at least one comorbidity and were taking at least 1 medication in 84.7% and 80.6% of the cases respectively, compared with correspondingly 47.4% and 37.4% in group 1 (p0.001). Nonetheless, the occurrence of serous (G3/G4) adverse events did not increase among the older group. Creatinine serum levels 1.1 g/dl, estimated glomerular filtration rate (eGFR)

Johns Hopkins Patients' Guide to Ovarian Cancer

Author : Ritu Salani
Publisher : Jones & Bartlett Publishers
ISBN 13 : 1449611176
Total Pages : 132 pages
Book Rating : 4.4/5 (496 download)

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Book Synopsis Johns Hopkins Patients' Guide to Ovarian Cancer by : Ritu Salani

Download or read book Johns Hopkins Patients' Guide to Ovarian Cancer written by Ritu Salani and published by Jones & Bartlett Publishers. This book was released on 2009-11-04 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Johns Hopkins Patients’ Guide to Ovarian Cancer is a concise, easy-to-follow “how to” guide that puts you on a path to wellness by explaining ovarian cancer treatments from start to finish. It guides you through the overwhelming maze of treatment decisions, simplifies the complicated schedule that lies ahead, and provides valuable tools to help you to put together your plan of care. Empower yourself with accurate, understandable information that will give you the ability to confidently participate in the decision making about your care and treatment.

Ovarian Cancers

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309380499
Total Pages : 397 pages
Book Rating : 4.3/5 (93 download)

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Book Synopsis Ovarian Cancers by : National Academies of Sciences, Engineering, and Medicine

Download or read book Ovarian Cancers written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2016-04-25 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: In an era of promising advances in cancer research, there are considerable and even alarming gaps in the fundamental knowledge and understanding of ovarian cancer. Researchers now know that ovarian cancer is not a single disease-several distinct subtypes exist with different origins, risk factors, genetic mutations, biological behaviors, and prognoses. However, persistent questions have impeded progress toward improving the prevention, early detection, treatment, and management of ovarian cancers. Failure to significantly improve morbidity and mortality during the past several decades is likely due to several factors, including the lack of research being performed by specific disease subtype, lack of definitive knowledge of the cell of origin and disease progression, and incomplete understanding of genetic and non-genetic risk factors. Ovarian Cancers examines the state of the science in ovarian cancer research, identifies key gaps in the evidence base and the challenges to addressing those gaps, considers opportunities for advancing ovarian cancer research, and examines avenues for translation and dissemination of new findings and communication of new information to patients and others. This study makes recommendations for public- and private-sector efforts that could facilitate progress in reducing the incidence of morbidity and mortality from ovarian cancers.

Diagnosis and Management of Ovarian Disorders

Author : Albert Altchek
Publisher : Elsevier
ISBN 13 : 008049451X
Total Pages : 595 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Diagnosis and Management of Ovarian Disorders by : Albert Altchek

Download or read book Diagnosis and Management of Ovarian Disorders written by Albert Altchek and published by Elsevier. This book was released on 2003-09-04 with total page 595 pages. Available in PDF, EPUB and Kindle. Book excerpt: This updated second edition of Diagnosis and Management of Ovarian Disorders provides thorough, yet succinct insight into the ever-changing realm of ovarian disorders. It presents a novel multidisciplinary approach to the subject as described by clinicians, surgeons, pathologists, basic scientists and related medical researchers. Topics covered include reproductive technology, early diagnosis of ovarian cancer, and management of menopause among others. The breadth of information provided by this book will appeal to clinicians and researchers involved in the study and treatment of ovarian disorders.KEY FEATURES* Includes updated information on early diagnosis of ovarian cancer* Reviews new diagnostic techniques for ovarian disorders* Discusses latest information on reproductive technology* Presents translational treatment linking laboratory research with clinical medicine

Ovarian Cancers

Author : Eric Pujade-Lauraine
Publisher : Springer
ISBN 13 : 3319321102
Total Pages : 288 pages
Book Rating : 4.3/5 (193 download)

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Book Synopsis Ovarian Cancers by : Eric Pujade-Lauraine

Download or read book Ovarian Cancers written by Eric Pujade-Lauraine and published by Springer. This book was released on 2016-10-17 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an overview of the latest developments in the concepts and management of ovarian cancer. The new data presented throughout opens the way to radically different therapeutic approaches. Surgery remains the core of ovarian cancer treatment, but its ultimate goal and the standard surgical procedure have evolved, giving rise to the question of how to label expert centers for debulking surgery. Neo-adjuvant chemotherapy is becoming more popular and is also a new field for testing novel drug combinations. Over recent years, ovarian cancer management has embraced molecular biology. It is now more correct to talk about cancers of the ovary rather than ovarian cancer, since it is not a unique disease but several entities with different molecular drivers. The significant advances in drugs targeting the microenvironment or the tumor cell DNA repair mechanisms are presented in detail together with exciting future perspectives. All these advances would not have been possible without collaborative groups such as the GINECO group in France and their integration in wider clinical research networks at the European (ENGOT) and international (GCIG) level.

Interval Debulking Surgery for Advanced Ovarian Cancer in Elderly Patients (>70y): Does the Age Matter?

Author : Roberto Tozzi
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (116 download)

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Book Synopsis Interval Debulking Surgery for Advanced Ovarian Cancer in Elderly Patients (>70y): Does the Age Matter? by : Roberto Tozzi

Download or read book Interval Debulking Surgery for Advanced Ovarian Cancer in Elderly Patients (>70y): Does the Age Matter? written by Roberto Tozzi and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Background:Elderly ovarian cancer (OC) patients are more likely to be managed suboptimally, with worse clinical outcomes as a result. Strategies to decrease morbidity are lacking.Methodology:Retrospective analysis for consecutive patients with advanced stage OC (IIIC-IV) who were managed in Oxford University Hospital between January 2016 and July 2018 were analysed. All patients underwent neoadjuvant chemotherapy (NACT) and interval debulking surgery (IDS) according to our institution protocol. We divided patients into two groups: an u201colder groupu201d (ageu226570 years) (Group 1) and a u201cyounger group (age

Handbook of Geriatric Oncology

Author : Beatriz Korc-Grodzicki, MD, PhD
Publisher : Springer Publishing Company
ISBN 13 : 1617052825
Total Pages : 385 pages
Book Rating : 4.6/5 (17 download)

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Book Synopsis Handbook of Geriatric Oncology by : Beatriz Korc-Grodzicki, MD, PhD

Download or read book Handbook of Geriatric Oncology written by Beatriz Korc-Grodzicki, MD, PhD and published by Springer Publishing Company. This book was released on 2017-06-16 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Geriatric Oncology is a practical resource for oncologists and related clinicians who want to provide comprehensive, patient-centered care to the elderly cancer patient. Divided into nine succinct sections, it includes topics spanning an Overview of Geriatric Oncology and Aging, Geriatric Syndromes, Geriatric Assessment, Select Cancers Commonly Diagnosed in the Elderly, Communication with the Older Cancer Patient, the Nursing Home Patient with Cancer, Models of Care and Survivorship, Palliative Care, and Integrative Medicine. Complex issues such as the physiologic changes of aging and their effect on cancer, corresponding social and psychological aspects that accompany aging and a cancer diagnosis, assessment of frailty, managing comorbid conditions and diseases, effective communication among healthcare providers, the patient and caregivers, as well as the risks and benefits of cancer screening, are made simpler with helpful clinical guidance and clinical pearls. Spearheaded by world experts in geriatric oncology from Memorial Sloan Kettering Cancer Center in New York, this book is the definitive resource for oncologists and related clinicians to meet the demands of clinical management along the continuum of geriatric cancer care. Key Features: Provides best practices for evaluating geriatric syndromes such as functional dependency, falls, cognitive impairment and dementia, delirium, depression and anxiety, social isolation as well as syndromes related to nutrition, comorbid conditions, and polypharmacy. Includes practical guidance on when to treat and when not to treat cancer in older patients Discusses unique factors associated with breast cancer, prostate cancer, colorectal cancer, lung cancer, ovarian cancer, bladder cancer, pancreatic cancer, head and neck cancers, and myelodysplastic syndromes in the elderly that impact care plans and treatment.

Cancer in the Elderly

Author : Ian S. Fentiman
Publisher :
ISBN 13 :
Total Pages : 204 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Cancer in the Elderly by : Ian S. Fentiman

Download or read book Cancer in the Elderly written by Ian S. Fentiman and published by . This book was released on 1994 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aged population is at the greatest risk for cancer and therefore the disease is becoming any ever-increasing problem as human longevity increases. Approximately one half of the common cancers occur in patients over 70. Paradoxically, however, they are excluded from clinical trails on grounds of "frailty". Such data as are available indicated that elderly cancer patients are often undertreated, giving rise to an increased risk of recurrence and death. This book considers the relationship between aging and malignancy and brings together a breadth of international clinical research on cancer in the elderly. The management of common tumors is examined from the perspective of surgery, radiotherapy, and medical oncology. Additionally, the psychosocial problems of the elderly and the specific needs for palliative care in older patients are discussed. Cancer in the Elderly makes recommendations for optimal treatment, but the authors also identify areas where knowledge is scarce and there is a need for both basic and applied research.

Surgery for Ovarian Cancer

Author : Robert E. Bristow
Publisher : CRC Press
ISBN 13 : 0429578857
Total Pages : 437 pages
Book Rating : 4.4/5 (295 download)

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Book Synopsis Surgery for Ovarian Cancer by : Robert E. Bristow

Download or read book Surgery for Ovarian Cancer written by Robert E. Bristow and published by CRC Press. This book was released on 2019-02-21 with total page 437 pages. Available in PDF, EPUB and Kindle. Book excerpt: Updated and expanded, the third edition of Surgery for Ovarian Cancer focuses on essential techniques for the effective management of ovarian cancer. It reflects the most contemporary science and surgical applications for the management of patients with ovarian cancer and related peritoneal surface malignancies. This new edition takes a step-by-step approach and includes new intraoperative photographs and videos illustrating surgical procedures. It is principally devoted to the technical aspects of cytoreductive surgery, with chapters divided according to anatomic region. The chapters cover relevant anatomical considerations, surgical challenges specific to each region, and operative approaches and techniques favored by the authors. The list of contributing authors has been expanded from the previous edition and includes international and world-renowned experts from the fields of gynecologic oncology and surgical oncology. The topics of minimally invasive surgery, secondary cytoreduction, palliative surgery, and postoperative care are also covered in detail. New to the third edition are chapters on preoperative risk stratification, regional therapeutics and peritonectomy procedures, and quality assurance relating to ovarian cancer surgery. This comprehensive text is essential reading for all practitioners working with patients with ovarian cancers.

Cancer and Aging Handbook

Author : Keith M. Bellizzi
Publisher : John Wiley & Sons
ISBN 13 : 1118312481
Total Pages : 499 pages
Book Rating : 4.1/5 (183 download)

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Book Synopsis Cancer and Aging Handbook by : Keith M. Bellizzi

Download or read book Cancer and Aging Handbook written by Keith M. Bellizzi and published by John Wiley & Sons. This book was released on 2012-07-20 with total page 499 pages. Available in PDF, EPUB and Kindle. Book excerpt: A state-of-the-art, multidisciplinary approach to cancer and aging With the majority of cancers occurring in individuals over the age of 65 against a backdrop of an expanding aging population, there is an urgent need to integrate the areas of clinical oncology and geriatric care. This timely work tackles these issues head-on, presenting a truly multidisciplinary and international perspective on cancer and aging from world-renowned experts in geriatrics, oncology, behavioral science, psychology, gerontology, and public health. Unlike other books on geriatric oncology that focus mainly on treatment, Cancer and Aging Handbook: Research and Practice examines all phases of the cancer care continuum, from prevention through evidence-based diagnosis and treatment to end-of-life care. Detailed clinical and research information helps guide readers on effective patient care as well as caregiver training, research, and intervention. Coverage includes: Epidemiology of cancer in older adults, plus the unique physical, mental, and social issues involved Strategies and guidelines for prevention, screening, and treatment of older individuals with cancer The most common cancers in the elderly, including breast, colorectal, lung, prostate, and ovarian cancer Cancer survivorship in older adults as well as the all-critical issues of palliative care and pain management Emerging topics such as caregiver and family issues, different models of care, and cost considerations An essential resource for clinicians and caregivers as well as researchers interested in this evolving field, Cancer and Aging Handbook is also useful for public health professionals and policymakers who need to formulate services and allocate resources for the growing population of older cancer patients.

Problem Solving in Older Cancer Patients

Author : Alistair Ring
Publisher : Evidence-based Networks Ltd
ISBN 13 : 1846921104
Total Pages : 329 pages
Book Rating : 4.8/5 (469 download)

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Book Synopsis Problem Solving in Older Cancer Patients by : Alistair Ring

Download or read book Problem Solving in Older Cancer Patients written by Alistair Ring and published by Evidence-based Networks Ltd. This book was released on 2016-01-04 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: This practical manual in the care of older cancer patients won best oncology book in the BMA Medical Book Awards 2016, and is an essential tool created as a joint project of the Association of Cancer Physicians (ACP) and the British Geriatric Society (BGS). Written by 134 contributors who are all experts in their fields, it offers an overview of the latest developments, with 32 real life case studies. It is a valuable learning and reference resource for doctors, nurses, trainees and other professionals managing cancer in older patients. This evidence-based guidebook will assist the physician in managing the older cancer patient when implementing the appropriate treatment strategy, taking account of comorbidities, frailty, and patient choice. Each clinical case includes a concise discussion on patient presentation and of scenarios underpinning issues experienced by older patients followed by a clear appraisal of how the latest clinical research impacts on patient management. This large cohort of patients requires both innovative care and individual attention, and this carefully crafted book shares the experience of an expert multidisciplinary team in the interest of patient-centred care. It is essential reading for specialists in oncology, specialists in geriatric care, general physicians, doctors in training, oncology nurses, healthcare managers and administrators.