Orthobiologics

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Author :
Publisher : Springer Nature
ISBN 13 : 3030847446
Total Pages : 394 pages
Book Rating : 4.0/5 (38 download)

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Book Synopsis Orthobiologics by : Giuseppe Filardo

Download or read book Orthobiologics written by Giuseppe Filardo and published by Springer Nature. This book was released on 2021-12-02 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the evidence related to the use of injectable biologics to provide faster and better healing for musculoskeletal lesions and conditions. The authors discuss approaches, such as blood derivatives and cell concentrates, applied to lesions of muscles, ligaments, tendons, bones, meniscus and cartilage, as well as osteoarthritis. Chapters are written by some of the most influential opinion leaders in the field, with up-to-date review of the current literature, where the authors explore both the potential and the limitations of these minimally invasive and promising treatments. The first section is devoted to the formulations and rationale for the use of injectable orthobiologics, while the second section reviews current treatment methods applied to specific joints and pathologies – ranging from tendinopathies through non-unions to articular degenerative processes – as well as the results of these treatment approaches. The third section explores future perspectives, such as pluripotent stem cells, gene therapy, and the stimulation of intrinsic stromal cell niches. Appealing to a broad readership, this book will be of interest to both laboratory research scientists and clinicians, including orthopedists, sports physicians, physiatrists, and regenerative medicine experts.

Mesenchymal Stem Cell Therapy

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1627032002
Total Pages : 458 pages
Book Rating : 4.6/5 (27 download)

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Book Synopsis Mesenchymal Stem Cell Therapy by : Lucas G. Chase

Download or read book Mesenchymal Stem Cell Therapy written by Lucas G. Chase and published by Springer Science & Business Media. This book was released on 2012-12-12 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past decade, significant efforts have been made to develop stem cell-based therapies for difficult to treat diseases. Multipotent mesenchymal stromal cells, also referred to as mesenchymal stem cells (MSCs), appear to hold great promise in regards to a regenerative cell-based therapy for the treatment of these diseases. Currently, more than 200 clinical trials are underway worldwide exploring the use of MSCs for the treatment of a wide range of disorders including bone, cartilage and tendon damage, myocardial infarction, graft-versus-host disease, Crohn’s disease, diabetes, multiple sclerosis, critical limb ischemia and many others. MSCs were first identified by Friendenstein and colleagues as an adherent stromal cell population within the bone marrow with the ability to form clonogenic colonies in vitro. In regards to the basic biology associated with MSCs, there has been tremendous progress towards understanding this cell population’s phenotype and function from a range of tissue sources. Despite enormous progress and an overall increased understanding of MSCs at the molecular and cellular level, several critical questions remain to be answered in regards to the use of these cells in therapeutic applications. Clinically, both autologous and allogenic approaches for the transplantation of MSCs are being explored. Several of the processing steps needed for the clinical application of MSCs, including isolation from various tissues, scalable in vitro expansion, cell banking, dose preparation, quality control parameters, delivery methods and numerous others are being extensively studied. Despite a significant number of ongoing clinical trials, none of the current therapeutic approaches have, at this point, become a standard of care treatment. Although exceptionally promising, the clinical translation of MSC-based therapies is still a work in progress. The extensive number of ongoing clinical trials is expected to provide a clearer path forward for the realization and implementation of MSCs in regenerative medicine. Towards this end, reviews of current clinical trial results and discussions of relevant topics association with the clinical application of MSCs are compiled in this book from some of the leading researchers in this exciting and rapidly advancing field. Although not absolutely all-inclusive, we hope the chapters within this book can promote and enable a better understanding of the translation of MSCs from bench-to-bedside and inspire researchers to further explore this promising and quickly evolving field.

Stem Cell and Tissue Engineering

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Author :
Publisher : World Scientific
ISBN 13 : 9814317055
Total Pages : 473 pages
Book Rating : 4.8/5 (143 download)

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Book Synopsis Stem Cell and Tissue Engineering by : Song Li

Download or read book Stem Cell and Tissue Engineering written by Song Li and published by World Scientific. This book was released on 2011 with total page 473 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tissue engineering integrates knowledge and tools from biological sciences and engineering for tissue regeneration. A challenge for tissue engineering is to identify appropriate cell sources. The recent advancement of stem cell biology provides enormous opportunities to engineer stem cells for tissue engineering. The impact of stem cell technology on tissue engineering will be revolutionary. This book covers state-of-the-art knowledge on the potential of stem cells for the regeneration of a wide range of tissues and organs and the technologies for studying and engineering stem cells. It serves as a valuable reference book for researchers and students.

Regenerative Treatments in Sports and Orthopedic Medicine

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Author :
Publisher : Springer Publishing Company
ISBN 13 : 1617052892
Total Pages : 305 pages
Book Rating : 4.6/5 (17 download)

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Book Synopsis Regenerative Treatments in Sports and Orthopedic Medicine by : Gerard A. Malanga, MD

Download or read book Regenerative Treatments in Sports and Orthopedic Medicine written by Gerard A. Malanga, MD and published by Springer Publishing Company. This book was released on 2017-09-28 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: Regenerative medicine offers physicians new tools to help repair damaged tissue, alleviate pain, accelerate healing, and improve function for patients with degenerative conditions or sports injuries. Regenerative Treatments in Sports and Orthopedic Medicine is the first comprehensive book devoted to orthobiologic treatments for orthopedic conditions. Authored by experts in regenerative medicine, this evidence- and experience-based guide is written for clinicians looking to understand and effectively implement these treatments in their practices. Broad yet focused coverage of the scientific underpinnings, regulatory issues, staffing and equipment, nutritional and rehabilitation concerns, and orthobiologic interventions for specific clinical problems make this the ideal procedural reference for anyone working to restore function to athletes or other patients with musculoskeletal pathologies. Key Features Unparallelled coverage of clinical science and practical applications Written by pioneering leaders at the forefront of an emerging standard of care Evidence-based indications for initiating orthobiologic therapies Includes a review of important nomenclature for the novice Covers both Platelet Rich Plasma (PRP) and stem cell procedures A must-read guide for practitioners in academic and private practice settings

Cardiac Regeneration

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Author :
Publisher : Springer
ISBN 13 : 3319561065
Total Pages : 277 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Cardiac Regeneration by : Masaki Ieda

Download or read book Cardiac Regeneration written by Masaki Ieda and published by Springer. This book was released on 2017-10-27 with total page 277 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Volume of the series Cardiac and Vascular Biology offers a comprehensive and exciting, state-of-the-art work on the current options and potentials of cardiac regeneration and repair. Several techniques and approaches have been developed for heart failure repair: direct injection of cells, programming of scar tissue into functional myocardium, and tissue-engineered heart muscle support. The book introduces the rationale for these different approaches in cell-based heart regeneration and discusses the most important considerations for clinical translation. Expert authors discuss when, why, and how heart muscle can be salvaged. The book represents a valuable resource for stem cell researchers, cardiologists, bioengineers, and biomedical scientists studying cardiac function and regeneration.

Orthopedics of the Upper and Lower Limb

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Author :
Publisher : Springer Nature
ISBN 13 : 3030432866
Total Pages : 714 pages
Book Rating : 4.0/5 (34 download)

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Book Synopsis Orthopedics of the Upper and Lower Limb by : K. Mohan Iyer

Download or read book Orthopedics of the Upper and Lower Limb written by K. Mohan Iyer and published by Springer Nature. This book was released on 2020-07-07 with total page 714 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of this book provides a practical guide to the latest diagnostic and therapeutic techniques in orthopedics for both the upper and lower limb. Extensively revised chapters provide detailed step-by-step instructions on how to perform basic clinical and surface, anatomy examinations on joints including the hand, elbow and ankle. The application of relevant surgical procedures and post-operative management techniques are also detailed. New topics covered include cruciate ligament injuries, and robot assisted surgery. Orthopedics of the Upper and Lower Limb is an ideal resource for trainees and junior surgeons seeking an easy to follow clinical manual on how to successfully diagnose and treat patients with orthopedic disorders affecting both limbs. It is also of use to the experienced practitioner seeking a detailed resource on the latest advances in the field.

The Knee

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Author :
Publisher : Berlin : Springer-Verlag
ISBN 13 :
Total Pages : 214 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Knee by : W. Bandi

Download or read book The Knee written by W. Bandi and published by Berlin : Springer-Verlag. This book was released on 1978 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Stem Cell Cure

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Author :
Publisher : Humanix Books
ISBN 13 : 1630061190
Total Pages : 206 pages
Book Rating : 4.6/5 (3 download)

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Book Synopsis The Stem Cell Cure by : Gaurav K. Goswami

Download or read book The Stem Cell Cure written by Gaurav K. Goswami and published by Humanix Books. This book was released on 2020-03-31 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 150+ year lifespan of our ancient ancestors can be achieved once again by harnessing the power of our own cells with The Stem Cell Cure! Renowned regenerative and restorative sports medicine doctor Gaurav Goswami, M.D. provides advanced minimally invasive, non-surgical treatments to help his patients get back to peak performance levels – no matter their age. Harnessing the transformative power of stem cells is central to his expertise. In fact, stem cell therapy is proven to be effective in the treatment of many common conditions from arthritis and back pain to Alzheimer’s, Parkinson’s, and cancer. This book is an accessible and informative introduction to the amazing powers of Stem Cell Therapy – the biggest revolution in medicine since the discovery of penicillin, and a wave of the future. Co-authored by bestselling author and popular keynote speaker Kerry Johnson MBA PhD, The Stem Cell Cure provides specific ways for readers to boost their health and vitality for a lifetime by recovering, regenerating, and repairing injuries and disease.

Stem Cell Therapy: A Rising Tide: How Stem Cells Are Disrupting Medicine and Transforming Lives

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Author :
Publisher : Neil H Riordan
ISBN 13 : 9780999045305
Total Pages : 302 pages
Book Rating : 4.0/5 (453 download)

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Book Synopsis Stem Cell Therapy: A Rising Tide: How Stem Cells Are Disrupting Medicine and Transforming Lives by : Neil H. Riordan

Download or read book Stem Cell Therapy: A Rising Tide: How Stem Cells Are Disrupting Medicine and Transforming Lives written by Neil H. Riordan and published by Neil H Riordan. This book was released on 2017-06-20 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stem cells are the repair cells of your body. When there aren't enough of them, or they aren't working properly, chronic diseases can manifest and persist. From industry leaders, sport stars, and Hollywood icons to thousands of everyday, ordinary people, stem cell therapy has helped when standard medicine failed. Many of them had lost hope. These are their stories. Neil H Riordan, author of MSC: Clinical Evidence Leading Medicine's Next Frontier, the definitive textbook on clinical stem cell therapy, brings you an easy-to-read book about how and why stem cells work, and why they're the wave of the future.

Principles of Regenerative Medicine

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Publisher : Academic Press
ISBN 13 : 0123814235
Total Pages : 1203 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis Principles of Regenerative Medicine by : Anthony Atala

Download or read book Principles of Regenerative Medicine written by Anthony Atala and published by Academic Press. This book was released on 2010-12-16 with total page 1203 pages. Available in PDF, EPUB and Kindle. Book excerpt: Virtually any disease that results from malfunctioning, damaged, or failing tissues may be potentially cured through regenerative medicine therapies, by either regenerating the damaged tissues in vivo, or by growing the tissues and organs in vitro and implanting them into the patient. Principles of Regenerative Medicine discusses the latest advances in technology and medicine for replacing tissues and organs damaged by disease and of developing therapies for previously untreatable conditions, such as diabetes, heart disease, liver disease, and renal failure. - Key for all researchers and instituions in Stem Cell Biology, Bioengineering, and Developmental Biology - The first of its kind to offer an advanced understanding of the latest technologies in regenerative medicine - New discoveries from leading researchers on restoration of diseased tissues and organs

Orthopedic Stem Cell Surgery

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Author :
Publisher : Springer Nature
ISBN 13 : 3030732991
Total Pages : 281 pages
Book Rating : 4.0/5 (37 download)

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Book Synopsis Orthopedic Stem Cell Surgery by : Jeffrey N. Weiss

Download or read book Orthopedic Stem Cell Surgery written by Jeffrey N. Weiss and published by Springer Nature. This book was released on 2021-06-26 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a concise guide that provides an easy to follow template for other physicians to develop similar stem cell based treatments within their specialty. It identifies and summarizes the current world-wide orthopedic stem cell trials. Organized into three sections, Orthopedic Stem Cell Surgery presents clinical studies that examine the procedures for setting up and implementing stem cell surgery within the specialty of orthopedics. Chapters maintain an accessible narrative while also addressing complex studies related to orthopedic stem cell surgery. A sister text to the recently published, Retinal and Optic Nerve Stem Cell Surgery, and Neurologic Stem Cell Surgery this expertly written book examines critical Institutional Review Board (IRB) approved studies.

Orthopedic Regenerative Medicine

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Author :
Publisher : AuthorHouse
ISBN 13 : 1438940998
Total Pages : 334 pages
Book Rating : 4.4/5 (389 download)

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Book Synopsis Orthopedic Regenerative Medicine by : Alimorad Farshchian, M.D.

Download or read book Orthopedic Regenerative Medicine written by Alimorad Farshchian, M.D. and published by AuthorHouse. This book was released on 2009 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Handbook of Histology Methods for Bone and Cartilage

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1592594174
Total Pages : 582 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Handbook of Histology Methods for Bone and Cartilage by : Yuehuei H. An

Download or read book Handbook of Histology Methods for Bone and Cartilage written by Yuehuei H. An and published by Springer Science & Business Media. This book was released on 2003-05-01 with total page 582 pages. Available in PDF, EPUB and Kindle. Book excerpt: Histotechnology and histomorphometry are the major methodologies in bone and cartila- related research. Handbook of Histology Methods for Bone and Cartilage is an outgrowth of the editors’ own quest for information on bone and cartilage histology and histomorphometry. It is designed to be an experimental guide for personnel who work in the areas of basic and clinical bone and cartilage, orthopedic, or dental research. It is the first inclusive and organized reference book on histological and histomorphometrical techniques on bone and cartilage specimens. The topic has not previously been covered adequately by any existing books in the field. Handbook of Histology Methods for Bone and Cartilage has six major parts and is designed to be concise as well as inclusive, and more practical than theoretical. The text is simple and straightforward. Large numbers of tables, line drawings, and micro- or macro-photographs, are used to help readers better understand the content. Full bibliographies at the end of each chapter guide readers to more detailed information. A book of this length cannot discuss every method for bone and cartilage histology that has been used over the years, but it is hoped that major methods and their applications have been included.

Articular Cartilage Lesions

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 0387215530
Total Pages : 346 pages
Book Rating : 4.3/5 (872 download)

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Book Synopsis Articular Cartilage Lesions by : Brian J. Cole

Download or read book Articular Cartilage Lesions written by Brian J. Cole and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drs. Cole and Malek, recognized leaders in the field, wrote this cutting-edge text to fill the void in the literature regarding the management of articular cartilage disease and meniscal deficiency. The book enables orthopedic surgeons to develop an evidence-based decision-making framework that guides the management of articular cartilage lesions. Carefully chosen contributors provide readers with a practical background in articular lesions, patient assessment, and management strategies. Subsequent chapters address the gamut of current surgical techniques, from arthroscopy and debridement to unicondylar arthroplasty, in a step-by-step manner. More than 500 detailed illustrations, many in color, help readers understand and master treatments. Case studies, which include preoperative planning and postoperative outcomes, reinforce the decision-making process. Nearly every permutation and treatment option is covered, making this text a prime resource for surgeons committed to exercising sound judgement.

Stem Cell Therapies

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Author :
Publisher : National Academy Press
ISBN 13 : 9780309303002
Total Pages : 108 pages
Book Rating : 4.3/5 (3 download)

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Book Synopsis Stem Cell Therapies by : Adam C. Berger

Download or read book Stem Cell Therapies written by Adam C. Berger and published by National Academy Press. This book was released on 2014-06-18 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stem cells offer tremendous promise for advancing health and medicine. Whether being used to replace damaged cells and organs or else by supporting the body's intrinsic repair mechanisms, stem cells hold the potential to treat such debilitating conditions as Parkinson's disease, diabetes, and spinal cord injury. Clinical trials of stem cell treatments are under way in countries around the world, but the evidence base to support the medical use of stem cells remains limited. Despite this paucity of clinical evidence, consumer demand for treatments using stem cells has risen, driven in part by a lack of available treatment options for debilitating diseases as well as direct-to-consumer advertising and public portrayals of stem cell-based treatments. Clinics that offer stem cell therapies for a wide range of diseases and conditions have been established throughout the world, both in newly industrialized countries such as China, India, and Mexico and in developed countries such as the United States and various European nations. Though these therapies are often promoted as being established and effective, they generally have not received stringent regulatory oversight and have not been tested with rigorous trials designed to determine their safety and likely benefits. In the absence of substantiated claims, the potential for harm to patients - as well as to the field of stem cell research in general - may outweigh the potential benefits. To explore these issues, the Institute of Medicine, the National Academy of Sciences, and the International Society for Stem Cell Research held a workshop in November 2013. "Stem Cell Therapies" summarizes the workshop. Researchers, clinicians, patients, policy makers, and others from North America, Europe, and Asia met to examine the global pattern of treatments and products being offered, the range of patient experiences, and options to maximize the well-being of patients, either by protecting them from treatments that are dangerous or ineffective or by steering them toward treatments that are effective. This report discusses the current environment in which patients are receiving unregulated stem cell offerings, focusing on the treatments being offered and their risks and benefits. The report considers the evidence base for clinical application of stem cell technologies and ways to assure the quality of stem cell offerings.

Stem Cell Therapy for Diabetes

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1607613662
Total Pages : 294 pages
Book Rating : 4.6/5 (76 download)

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Book Synopsis Stem Cell Therapy for Diabetes by : Shimon Efrat

Download or read book Stem Cell Therapy for Diabetes written by Shimon Efrat and published by Springer Science & Business Media. This book was released on 2009-12-01 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stem Cell Therapy for Diabetes, one of the latest installments of the Stem Cell Biology and Regenerative Medicine series, reviews the three main approaches for generation of sufficient numbers of insulin-producing cells for restoration of an adequate beta-cell mass: beta-cell expansion, stem-cell differentiation, and nuclear reprogramming. Adeptly collecting the research of the leading scientists in the field, Stem Cell Therapy for Diabetes compares the merits of employing autologous versus banked allogeneic cell sources for generation of surrogate beta cells, and addresses tissue engineering and ways for cell protection from recurring autoimmunity and graft rejection. Stem Cell Therapy for Diabetes provides essential reading for those especially interested in tracking the progress in applying of one of the most exciting new developments in bio-medicine towards a cure for diabetes.

Atlas of Ultrasound-Guided Musculoskeletal Injections

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Author :
Publisher : McGraw Hill Professional
ISBN 13 : 0071772049
Total Pages : 478 pages
Book Rating : 4.0/5 (717 download)

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Book Synopsis Atlas of Ultrasound-Guided Musculoskeletal Injections by : Gerard Malanga

Download or read book Atlas of Ultrasound-Guided Musculoskeletal Injections written by Gerard Malanga and published by McGraw Hill Professional. This book was released on 2014-03-22 with total page 478 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clear, concise description of more than 100 US-guided injections in musculoskeletal medicine. Atlas of Ultrasound-Guided Musculoskeletal Injections includes numerous tips and tricks from the field's most experienced and respected practitioners. This unique and state-of–the-art text is ideal for physiatrists, rheumatologists, sports medicine physicians, radiologists, pain medicine specialists, and orthopedic surgeons. With a focus on safety and efficacy, this atlas is a worthwhile investment for any practitioner looking to add ultrasound-guided procedures to their practice or is looking to sharpen their skills. The book opens with informative coverage of the fundamentals of MSK US, including ultrasound physics, preparation and set-up for MSK US procedures, and the rationale and evidence for performing these procedures. The main body of the book dedicates one chapter to a specific US-guided injection or procedure. Each chapter design includes sections on key points, pertinent anatomy, common pathology, US imaging, indications, and technique. The book is divided into 8 sections: Shoulder Elbow Hand and wrist Pelvis Knee Foot and ankle Special procedures (rotator cuff, Percutaneous Trigger finger release, Ultrasound-guided Carpal Tunnel release, and Tenex) Atlas of Ultrasound-Guided Musculoskeletal Injections includes coverage of the full spectrum of procedures, ranging from basic US guided joint injections to perinerual injections, tenotomies, and surgical procedures such as percutaneous A1 pulley release, making the book the field's first true cornerstone text and the "go to" resource for any clinician interested in the subject.