Author :
Publisher :
ISBN 13 :
Total Pages : 29 pages
Book Rating : 4.:/5 (742 download)
Book Synopsis Oral Contraceptives Use by Young Women Reduces Peak Bone Mass by :
Download or read book Oral Contraceptives Use by Young Women Reduces Peak Bone Mass written by and published by . This book was released on 2002 with total page 29 pages. Available in PDF, EPUB and Kindle. Book excerpt: The goal of these studies was to determine the role that hypoandrogenemia plays in the effects of oral contraceptives (OC) on bone metabolism and peak bone mass (PBM) in young female rats. Adolescent/young adult Sprague-Dawley rats were treated with 1) placebo, 2) OC, 3) OC supplemented with an androgen (methyltestosterone), or 4) an anti-androgen (bicalutamide) to determine the potential role that suppression of androgens plays on bone metabolism, bone architecture, and the attainment of PBM. Our specific aims were to determine: 1. If oral contraceptive steroid (OC) treatment leads to decreased peak bone mass in young intact female rats. Findings: OC use decreased the peak bone mass of young intact females rats. 2. If the addition of a non-aromatizable androgenic steroid to OCs prevents the detrimental effects of OC use on peak bone mass. Findings: The non