Optimization Of Rna Purification And Analysis For Automated Pre Symptomatic Disease Diagnostics

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Henry's Clinical Diagnosis and Management by Laboratory Methods E-Book

Author : Richard A. McPherson
Publisher : Elsevier Health Sciences
ISBN 13 : 0323413153
Total Pages : 1823 pages
Book Rating : 4.3/5 (234 download)

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Book Synopsis Henry's Clinical Diagnosis and Management by Laboratory Methods E-Book by : Richard A. McPherson

Download or read book Henry's Clinical Diagnosis and Management by Laboratory Methods E-Book written by Richard A. McPherson and published by Elsevier Health Sciences. This book was released on 2017-04-05 with total page 1823 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recognized as the definitive reference in laboratory medicine since 1908, Henry's Clinical Diagnosis continues to offer state-of-the-art guidance on the scientific foundation and clinical application of today's complete range of laboratory tests. Employing a multidisciplinary approach, it presents the newest information available in the field, including new developments in technologies and the automation platforms on which measurements are performed. Provides guidance on error detection, correction, and prevention, as well as cost-effective test selection. Features a full-color layout, illustrations and visual aids, and an organization based on organ system. Features the latest knowledge on cutting-edge technologies of molecular diagnostics and proteomics. Includes a wealth of information on the exciting subject of omics; these extraordinarily complex measurements reflect important changes in the body and have the potential to predict the onset of diseases such as diabetes mellitus. Coverage of today's hottest topics includes advances in transfusion medicine and organ transplantation; molecular diagnostics in microbiology and infectious diseases; point-of-care testing; pharmacogenomics; and the microbiome. Toxicology and Therapeutic Drug Monitoring chapter discusses the necessity of testing for therapeutic drugs that are more frequently being abused by users.

Rapid Cycle Real-Time PCR

Author : S. Meuer
Publisher : Springer Science & Business Media
ISBN 13 : 3642595243
Total Pages : 390 pages
Book Rating : 4.6/5 (425 download)

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Book Synopsis Rapid Cycle Real-Time PCR by : S. Meuer

Download or read book Rapid Cycle Real-Time PCR written by S. Meuer and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first comprehensive treatise on Rapid Cycle Real-Time PCR. With amplification times of 15-30 minutes of on-line detection and analysis, nucleic acid quantification of mutation analysis finally becomes a routine, powerful and rapid method. Focusing primarily on the LightCycler, an instrument that combines Rapid Cycle PCR with fluorescent monitoring, this technology provides convenient analysis by melting temperatures. PCR products can be identified by product Tm, and single base mismatches can easily be genotyped by probe Tm. Methods chapters detail the theory behind quantification of mutation analysis; the design of synthesis of fluorescent hybridization probes of the preparation of template DNA. Application chapters apply nucleid acid quantification to infectious organisms of intracellular messengers and mutation detection to somatic of acquired mutations.

Epigenetic Biomarkers and Diagnostics

Author : Jose Luis Garcia-Gimenez
Publisher : Academic Press
ISBN 13 : 0128019212
Total Pages : 698 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Epigenetic Biomarkers and Diagnostics by : Jose Luis Garcia-Gimenez

Download or read book Epigenetic Biomarkers and Diagnostics written by Jose Luis Garcia-Gimenez and published by Academic Press. This book was released on 2015-12-07 with total page 698 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epigenetic Biomarkers and Diagnostics comprises 31 chapters contributed by leading active researchers in basic and clinical epigenetics. The book begins with the basis of epigenetic mechanisms and descriptions of epigenetic biomarkers that can be used in clinical diagnostics and prognostics. It goes on to discuss classical methods and next generation sequencing-based technologies to discover and analyze epigenetic biomarkers. The book concludes with an account of DNA methylation, post-translational modifications and noncoding RNAs as the most promising biomarkers for cancer (i.e. breast, lung, colon, etc.), metabolic disorders (i.e. diabetes and obesity), autoimmune diseases, infertility, allergy, infectious diseases, and neurological disorders. The book describes the challenging aspects of research in epigenetics, and current findings regarding new epigenetic elements and modifiers, providing guidance for researchers interested in the most advanced technologies and tested biomarkers to be used in the clinical diagnosis or prognosis of disease. - Focuses on recent progress in several areas of epigenetics, general concepts regarding epigenetics, and the future prospects of this discipline in clinical diagnostics and prognostics - Describes the importance of the quality of samples and clinical associated data, and also the ethical issues for epigenetic diagnostics - Discusses the advances in epigenomics technologies, including next-generation sequencing based tools and applications - Expounds on the utility of epigenetic biomarkers for diagnosis and prognosis of several diseases, highlighting the study of these biomarkers in cancer, cardiovascular and metabolic diseases, infertility, and infectious diseases - Includes a special section that discusses the relevance of biobanks in the maintenance of high quality biosamples and clinical-associated data, and the relevance of the ethical aspects in epigenetic studies

Disease Control Priorities, Third Edition (Volume 6)

Author : King K. Holmes
Publisher : World Bank Publications
ISBN 13 : 1464805253
Total Pages : 1027 pages
Book Rating : 4.4/5 (648 download)

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Book Synopsis Disease Control Priorities, Third Edition (Volume 6) by : King K. Holmes

Download or read book Disease Control Priorities, Third Edition (Volume 6) written by King K. Holmes and published by World Bank Publications. This book was released on 2017-11-06 with total page 1027 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.

Cumulated Index Medicus

Author :
Publisher :
ISBN 13 :
Total Pages : 1472 pages
Book Rating : 4.:/5 (31 download)

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Book Synopsis Cumulated Index Medicus by :

Download or read book Cumulated Index Medicus written by and published by . This book was released on 1991 with total page 1472 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Medical Biosensors for Point of Care (POC) Applications

Author : Roger Narayan
Publisher : Woodhead Publishing
ISBN 13 : 0081000782
Total Pages : 318 pages
Book Rating : 4.0/5 (81 download)

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Book Synopsis Medical Biosensors for Point of Care (POC) Applications by : Roger Narayan

Download or read book Medical Biosensors for Point of Care (POC) Applications written by Roger Narayan and published by Woodhead Publishing. This book was released on 2016-08-21 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medical Biosensors for Point of Care (POC) Applications discusses advances in this important and emerging field which has the potential to transform patient diagnosis and care. Part 1 covers the fundamentals of medical biosensors for point-of-care applications. Chapters in part 2 go on to look at materials and fabrication of medical biosensors while the next part looks at different technologies and operational techniques. The final set of chapters provide an overview of the current applications of this technology. Traditionally medical diagnostics have been dependent on sophisticated technologies which only trained professionals were able to operate. Recent research has focused on creating point-of-care diagnostic tools. These biosensors are miniaturised, portable, and are designed to be used at the point-of-care by untrained individuals, providing real-time and remote health monitoring. - Provides essential knowledge for designers and manufacturers of biosensors for point-of-care applications - Provides comprehensive coverage of the fundamentals, materials, technologies, and applications of medical biosensors for point-of-care applications - Includes contributions from leading international researchers with extensive experience in developing medical biosensors - Discusses advances in this important and emerging field which has the potential to transform patient diagnosis and care

Combinatorial Group Testing and Its Applications

Author : Dingzhu Du
Publisher : World Scientific
ISBN 13 : 9810241070
Total Pages : 337 pages
Book Rating : 4.8/5 (12 download)

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Book Synopsis Combinatorial Group Testing and Its Applications by : Dingzhu Du

Download or read book Combinatorial Group Testing and Its Applications written by Dingzhu Du and published by World Scientific. This book was released on 2000 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: Group testing has been used in medical, chemical and electrical testing, coding, drug screening, pollution control, multiaccess channel management, and recently in data verification, clone library screening and AIDS testing. The mathematical model can be either combinatorial or probabilistic. This book summarizes all important results under the combinatorial model, and demonstrates their applications in real problems. Some other search problems, including the famous counterfeit-coins problem, are also studied in depth. There are two reasons for publishing a second edition of this book. The first is the usual need to update the text (after six years) and correct errors. The second -- and more important -- reason is to accommodate the recent sudden growth of interest in applying the idea of group testing to clone library screening. This development is much more than just a new application, since the new application brings with it new objectives which require a new twist of theory. It also embraces the growing importance of two topics: nonadaptive algorithms and error tolerance. Two new chapters, one on clone library screening and the other on error tolerance, have been added. Also included is a new chapter on counterfeit coins, the most famous search problem historically, which recently drew on an unexpected connection to some deep mathematical theory to yield new results. Finally, the chapters have been recognized into parts to provide focuses and perspectives.

Index Medicus

Author :
Publisher :
ISBN 13 :
Total Pages : 2098 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Index Medicus by :

Download or read book Index Medicus written by and published by . This book was released on 2004 with total page 2098 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.

Filoviruses

Author : Jens Kuhn
Publisher : Springer Science & Business Media
ISBN 13 : 3211694951
Total Pages : 410 pages
Book Rating : 4.2/5 (116 download)

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Book Synopsis Filoviruses by : Jens Kuhn

Download or read book Filoviruses written by Jens Kuhn and published by Springer Science & Business Media. This book was released on 2008-05-29 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first comprehensive review of the world literature on filovirus research and provides the most extensive bibliography of the subject yet published. There is special emphasis on foreign literature that has never been summarized. Every aspect of filovirus research, including their history, epidemiology, clinical picture, pathology, molecular biology, and political aspects are reviewed in detail.

CRISPR-Cas Systems

Author : Rodolphe Barrangou
Publisher : Springer Science & Business Media
ISBN 13 : 364234657X
Total Pages : 300 pages
Book Rating : 4.6/5 (423 download)

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Book Synopsis CRISPR-Cas Systems by : Rodolphe Barrangou

Download or read book CRISPR-Cas Systems written by Rodolphe Barrangou and published by Springer Science & Business Media. This book was released on 2012-12-13 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: CRISPR/Cas is a recently described defense system that protects bacteria and archaea against invasion by mobile genetic elements such as viruses and plasmids. A wide spectrum of distinct CRISPR/Cas systems has been identified in at least half of the available prokaryotic genomes. On-going structural and functional analyses have resulted in a far greater insight into the functions and possible applications of these systems, although many secrets remain to be discovered. In this book, experts summarize the state of the art in this exciting field.

Laboratory Biosafety Guidelines

Author : Laboratory Centre for Disease Control (Canada)
Publisher :
ISBN 13 :
Total Pages : 92 pages
Book Rating : 4.:/5 (31 download)

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Book Synopsis Laboratory Biosafety Guidelines by : Laboratory Centre for Disease Control (Canada)

Download or read book Laboratory Biosafety Guidelines written by Laboratory Centre for Disease Control (Canada) and published by . This book was released on 1996 with total page 92 pages. Available in PDF, EPUB and Kindle. Book excerpt: The focus of this document is on the use of bacteria, viruses, parasites, fungi, and other infectious agents which are pathogenic to humans. The document provides guidelines for those who design, build, operate, or work in laboratories in which such pathogens are grown for research or development purposes. Sections of the document cover biohazard containment; regulations governing the import, export, and transport of pathogens; classification of biological agents according to risk; physical containment levels, and the physical and operational requirements for each level; large-scale production of micro-organisms, and related considerations regarding safety, containment, and transportation; and laboratory design. Appendices include information on safety equipment and systems for laboratories.

Computational Sustainability

Author : Jörg Lässig
Publisher : Springer
ISBN 13 : 3319318586
Total Pages : 277 pages
Book Rating : 4.3/5 (193 download)

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Book Synopsis Computational Sustainability by : Jörg Lässig

Download or read book Computational Sustainability written by Jörg Lässig and published by Springer. This book was released on 2016-04-20 with total page 277 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book at hand gives an overview of the state of the art research in Computational Sustainability as well as case studies of different application scenarios. This covers topics such as renewable energy supply, energy storage and e-mobility, efficiency in data centers and networks, sustainable food and water supply, sustainable health, industrial production and quality, etc. The book describes computational methods and possible application scenarios.

Molecular Diagnostics: Promises and Possibilities

Author : Mousumi Debnath
Publisher : Springer Science & Business Media
ISBN 13 : 9048132614
Total Pages : 527 pages
Book Rating : 4.0/5 (481 download)

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Book Synopsis Molecular Diagnostics: Promises and Possibilities by : Mousumi Debnath

Download or read book Molecular Diagnostics: Promises and Possibilities written by Mousumi Debnath and published by Springer Science & Business Media. This book was released on 2010-01-29 with total page 527 pages. Available in PDF, EPUB and Kindle. Book excerpt: A rapid development in diverse areas of molecular biology and genetic engineering resulted in emergence of variety of tools. These tools are not only applicable to basic researches being carried out world over, but also exploited for precise detection of abnormal conditions in plants, animals and human body. Although a basic researcher is well versed with few techniques used by him/her in the laboratory, they may not be well acquainted with methodologies, which can be used to work out some of their own research problems. The picture is more blurred when the molecular diagnostic tools are to be used by physicians, scientists and technicians working in diagnostic laboratories in hospitals, industry and academic institutions. Since many of them are not trained in basics of these methods, they come across several gray areas in understanding of these tools. The accurate application of molecular diagnostic tools demands in depth understanding of the methodology for precise detection of the abnormal condition of living body. To meet the requirements of a good book on molecular diagnostics of students, physicians, scientists working in agricultural, veterinary, medical and pharmaceutical sciences, it needs to expose the reader lucidly to: Give basic science behind commonly used tools in diagnostics Expose the readers to detailed applications of these tools and Make them aware the availability of such diagnostic tools The book will attract additional audience of pathologists, medical microbiologists, pharmaceutical sciences, agricultural scientists and veterinary doctors if the following topics are incorporated at appropriate places in Unit II or separately as a part of Unit-III in the book. Molecular diagnosis of diseases in agricultural crops Molecular diagnosis of veterinary diseases. Molecular epidemiology, which helps to differentiate various epidemic strains and sources of disease outbreaks. Even in different units of the same hospital, the infections could be by different strains of the same species and the information becomes valuable for infection control strategies. Drug resistance is a growing problem for bacterial, fungal and parasitic microbes and the molecular biology tools can help to detect the drug resistance genes without the cultivation and in vitro sensitivity testing. Molecular diagnostics offers faster help in the selection of the proper antibiotic for the treatment of tuberculosis, which is a major problem of the in the developing world. The conventional culture and drug sensitivity testing of tuberculosis bacilli is laborious and time consuming, whereas molecular diagnosis offers rapid drug resistant gene detection even from direct clinical samples. The same approach for HIV, malaria and many more diseases needs to be considered. Molecular diagnostics in the detection of diseases during foetal life is an upcoming area in the foetal medicine in case of genetic abnormalities and infectious like TORCH complex etc. The book will be equally useful to students, scientists and professionals working in the field of molecular diagnostics.

CRISPR-Cas Enzymes

Author :
Publisher : Academic Press
ISBN 13 : 0128167610
Total Pages : 454 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis CRISPR-Cas Enzymes by :

Download or read book CRISPR-Cas Enzymes written by and published by Academic Press. This book was released on 2019-01-25 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: CRISPR-Cas Enzymes, Volume 616, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Topics covered in this release include CRISPR bioinformatics, A method for one-step assembly of Class 2 CRISPR arrays, Biochemical reconstitution and structural analysis of ribonucleoprotein complexes in Type I-E CRISPR-Cas systems, Mechanistic dissection of the CRISPR interference pathway in Type I-E CRISPR-Cas system, Site-specific fluorescent labeling of individual proteins within CRISPR complexes, Fluorescence-based methods for measuring target interference by CRISPR-Cas systems, Native State Structural Characterization of CRISRP Associated Complexes using Mass Spectrometry, and more. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in the Methods in Enzymology series - Updated release includes the latest information on the CRISPR-Cas Enzymes

Biotechnology Research Abstracts

Author :
Publisher :
ISBN 13 :
Total Pages : 966 pages
Book Rating : 4.:/5 ( download)

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Book Synopsis Biotechnology Research Abstracts by :

Download or read book Biotechnology Research Abstracts written by and published by . This book was released on 1991 with total page 966 pages. Available in PDF, EPUB and Kindle. Book excerpt: Monthly. Classified listing of references to worldwide articles dealing with all aspects of biotechnology. Also includes books and conferences. Each entry gives bibliographic information, institutional address of author(s), and abstract. Author and subject index.

Red Book Atlas of Pediatric Infectious Diseases

Author : American Academy of Pediatrics
Publisher :
ISBN 13 : 9781581102475
Total Pages : 440 pages
Book Rating : 4.1/5 (24 download)

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Book Synopsis Red Book Atlas of Pediatric Infectious Diseases by : American Academy of Pediatrics

Download or read book Red Book Atlas of Pediatric Infectious Diseases written by American Academy of Pediatrics and published by . This book was released on 2007 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: Based on key content from Red Book: 2006 Report of the Committee on Infectious Diseases, 27th Edition, the new Red Bookr Atlas is a useful quick reference tool for the clinical diagnosis and treatment of more than 75 of the most commonly seen pediatric infectious diseases. Includes more than 500 full-color images adjacent to concise diagnostic and treatment guidelines. Essential information on each condition is presented in the precise sequence needed in the clinical setting: Clinical manifestations, Etiology, Epidemiology, Incubation period, Diagnostic tests, Treatment

Angiogenesis Assays

Author : Carolyn A. Staton
Publisher : John Wiley & Sons
ISBN 13 : 047002934X
Total Pages : 410 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Angiogenesis Assays by : Carolyn A. Staton

Download or read book Angiogenesis Assays written by Carolyn A. Staton and published by John Wiley & Sons. This book was released on 2007-01-11 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: Angiogenesis, the development of new blood vessels from the existing vasculature, is essential for physiological growth and over 18,000 research articles have been published describing the role of angiogenesis in over 70 different diseases, including cancer, diabetic retinopathy, rheumatoid arthritis and psoriasis. One of the most important technical challenges in such studies has been finding suitable methods for assessing the effects of regulators of eh angiogenic response. While increasing numbers of angiogenesis assays are being described both in vitro and in vivo, it is often still necessary to use a combination of assays to identify the cellular and molecular events in angiogenesis and the full range of effects of a given test protein. Although the endothelial cell - its migration, proliferation, differentiation and structural rearrangement - is central to the angiogenic process, it is not the only cell type involved. the supporting cells, the extracellular matrix and the circulating blood with its cellular and humoral components also contribute. In this book, experts in the use of a diverse range of assays outline key components of these and give a critical appraisal of their strengths and weaknesses. Examples include assays for the proliferation, migration and differentiation of endothelial cells in vitro, vessel outgrowth from organ cultures, assessment of endothelial and mural cell interactions, and such in vivo assays as the chick chorioallantoic membrane, zebrafish, corneal, chamber and tumour angiogenesis models. These are followed by a critical analysis of the biological end-points currently being used in clinical trials to assess the clinical efficacy of anti-angiogenic drugs, which leads into a discussion of the direction future studies should take. This valuable book is of interest to research scientists currently working on angiogenesis in both the academic community and in the biotechnology and pharmaceutical industries. Relevant disciplines include cell and molecular biology, oncology, cardiovascular research, biotechnology, pharmacology, pathology and physiology.