OECD Series on Testing and Assessment Current Approaches in the Statistical Analysis of Ecotoxicity Data A guidance to application (annexes to this publication exist as a separate document)

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Author :
Publisher : OECD Publishing
ISBN 13 : 9264085270
Total Pages : 147 pages
Book Rating : 4.2/5 (64 download)

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Book Synopsis OECD Series on Testing and Assessment Current Approaches in the Statistical Analysis of Ecotoxicity Data A guidance to application (annexes to this publication exist as a separate document) by : OECD

Download or read book OECD Series on Testing and Assessment Current Approaches in the Statistical Analysis of Ecotoxicity Data A guidance to application (annexes to this publication exist as a separate document) written by OECD and published by OECD Publishing. This book was released on 2006-05-09 with total page 147 pages. Available in PDF, EPUB and Kindle. Book excerpt: This document describes the main statistical methods used for analysis of data from ecotoxicological studies .

Statistical Analysis of Ecotoxicity Studies

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1119488826
Total Pages : 416 pages
Book Rating : 4.1/5 (194 download)

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Book Synopsis Statistical Analysis of Ecotoxicity Studies by : John W. Green

Download or read book Statistical Analysis of Ecotoxicity Studies written by John W. Green and published by John Wiley & Sons. This book was released on 2018-07-04 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: A guide to the issues relevant to the design, analysis, and interpretation of toxicity studies that examine chemicals for use in the environment Statistical Analysis of Ecotoxicity Studies offers a guide to the design, analysis, and interpretation of a range of experiments that are used to assess the toxicity of chemicals. While the book highlights ecotoxicity studies, the methods presented are applicable to the broad range of toxicity studies. The text contains myriad datasets (from laboratory and field research) that clearly illustrate the book's topics. The datasets reveal the techniques, pitfalls, and precautions derived from these studies. The text includes information on recently developed methods for the analysis of severity scores and other ordered responses, as well as extensive power studies of competing tests and computer simulation studies of regression models that offer an understanding of the sensitivity (or lack thereof) of various methods and the quality of parameter estimates from regression models. The authors also discuss the regulatory process indicating how test guidelines are developed and review the statistical methodology in current or pending OECD and USEPA ecotoxicity guidelines. This important guide: Offers the information needed for the design and analysis to a wide array of ecotoxicity experiments and to the development of international test guidelines used to assess the toxicity of chemicals Contains a thorough examination of the statistical issues that arise in toxicity studies, especially ecotoxicity Includes an introduction to toxicity experiments and statistical analysis basics Includes programs in R and excel Covers the analysis of continuous and Quantal data, analysis of data as well as Regulatory Issues Presents additional topics (Mesocosm and Microplate experiments, mixtures of chemicals, benchmark dose models, and limit tests) as well as software Written for directors, scientists, regulators, and technicians, Statistical Analysis of Ecotoxicity Studies provides a sound understanding of the technical and practical issues in designing, analyzing, and interpreting toxicity studies to support or challenge chemicals for use in the environment.

Marine Ecotoxicology

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Author :
Publisher : Academic Press
ISBN 13 : 012803372X
Total Pages : 334 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Marine Ecotoxicology by : Julián Blasco

Download or read book Marine Ecotoxicology written by Julián Blasco and published by Academic Press. This book was released on 2016-08-05 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: Marine Ecotoxicology: Current Knowledge and Future Issues is the first unified resource to cover issues related to contamination, responses, and testing techniques of saltwater from a toxicological perspective. With its unprecedented focus on marine environments and logical chapter progression, this book is useful to graduate students, ecotoxicologists, risk assessors, and regulators involved or interested in marine waters. As human interaction with these environments increases, understanding of the pollutants and toxins introduced into the oceans becomes ever more critical, and this book builds a foundation of knowledge to assist scientists in studying, monitoring, and making decisions that affect both marine environments and human health. A team of world renowned experts provide detailed analyses of the most common contaminants in marine environments and explain the design and purpose of toxicity testing methods, while exploring the future of ecotoxicology studies in relation to the world’s oceans. As the threat of increasing pollution in marine environments becomes an ever more tangible reality, Marine Ecotoxicology offers insights and guidance to mitigate that threat. Provides practical tools and methods for assessing and monitoring the accumulation and effects of contaminants in marine environments Unites world renowned experts in marine ecotoxicology to deliver thorough and diverse perspectives Builds the foundation required for risk assessors and regulators to adequately assess and monitor the impact of pollution in marine environments Offers helpful insights and guidance to graduate students, ecotoxicologists, risk assessors, and regulators interested in mitigating threats to marine waters

OECD Guidelines for the Testing of Chemicals, Section 2 Test No. 249: Fish Cell Line Acute Toxicity - The RTgill-W1 cell line assay

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Author :
Publisher : OECD Publishing
ISBN 13 : 9264714138
Total Pages : 51 pages
Book Rating : 4.2/5 (647 download)

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Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 2 Test No. 249: Fish Cell Line Acute Toxicity - The RTgill-W1 cell line assay by : OECD

Download or read book OECD Guidelines for the Testing of Chemicals, Section 2 Test No. 249: Fish Cell Line Acute Toxicity - The RTgill-W1 cell line assay written by OECD and published by OECD Publishing. This book was released on 2021-06-18 with total page 51 pages. Available in PDF, EPUB and Kindle. Book excerpt: The RTgill-W1 cell line assay describes a 24-well plate format fish cell line acute toxicity test using the permanent cell line from rainbow trout (Oncorhynchus mykiss) gill, RTgill-W1. After 24 h of exposure to the test chemical, cell viability is assessed based on three fluorescent cell viability indicator dyes, measured on the same set of cells. Resazurin enters the cells in its non-fluorescent form and is converted to the fluorescent product, resorufin, by mitochondrial, microsomal or cytoplasmic oxidoreductases.

OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Report of the OECD Workshop on Statistical Analysis of Aquatic Toxicity Data

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Author :
Publisher : OECD Publishing
ISBN 13 : 9264078282
Total Pages : 133 pages
Book Rating : 4.2/5 (64 download)

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Book Synopsis OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Report of the OECD Workshop on Statistical Analysis of Aquatic Toxicity Data by : OECD

Download or read book OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Report of the OECD Workshop on Statistical Analysis of Aquatic Toxicity Data written by OECD and published by OECD Publishing. This book was released on 2002-05-10 with total page 133 pages. Available in PDF, EPUB and Kindle. Book excerpt: The workshop report reviews the options available for the analysis of data from ecotoxicity tests; compares their advantages and disadvantages; a recommends (a) the most appropriate approach for deriving summary parameter(s) and (b) further work to be undertaken.

OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Guidance Notes for Analysis and Evaluation of Repeat-Dose Toxicity Studies

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Author :
Publisher : OECD Publishing
ISBN 13 : 9264078487
Total Pages : 87 pages
Book Rating : 4.2/5 (64 download)

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Book Synopsis OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Guidance Notes for Analysis and Evaluation of Repeat-Dose Toxicity Studies by : OECD

Download or read book OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Guidance Notes for Analysis and Evaluation of Repeat-Dose Toxicity Studies written by OECD and published by OECD Publishing. This book was released on 2002-05-10 with total page 87 pages. Available in PDF, EPUB and Kindle. Book excerpt: This document presents a general guide to the analysis and evaluation of data from studies involving repeated exposures of toxicity test species to pesticides and other chemicals.

OECD Series on Testing and Assessment Guidance Document on the Reporting of Defined Approaches to be Used Within Integrated Approaches to Testing and Assessment

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Author :
Publisher : OECD Publishing
ISBN 13 : 9264274820
Total Pages : 23 pages
Book Rating : 4.2/5 (642 download)

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Book Synopsis OECD Series on Testing and Assessment Guidance Document on the Reporting of Defined Approaches to be Used Within Integrated Approaches to Testing and Assessment by : OECD

Download or read book OECD Series on Testing and Assessment Guidance Document on the Reporting of Defined Approaches to be Used Within Integrated Approaches to Testing and Assessment written by OECD and published by OECD Publishing. This book was released on 2017-04-13 with total page 23 pages. Available in PDF, EPUB and Kindle. Book excerpt: With a view to assisting the evaluation of integrated approaches to testing and assessment (IATA) in regulatory decision-making within OECD Member Countries, this guidance document provides a set of principles for reporting defined approaches to testing and assessment that can be used as one of ...

OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Guidance Notes for Analysis and Evaluation of Chronic Toxicity and Carcinogenicity Studies

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Author :
Publisher : OECD Publishing
ISBN 13 : 9264078495
Total Pages : 112 pages
Book Rating : 4.2/5 (64 download)

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Book Synopsis OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Guidance Notes for Analysis and Evaluation of Chronic Toxicity and Carcinogenicity Studies by : OECD

Download or read book OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Guidance Notes for Analysis and Evaluation of Chronic Toxicity and Carcinogenicity Studies written by OECD and published by OECD Publishing. This book was released on 2002-12-12 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt: These Guidance Notes outline core concepts in order to obviate the need to consult large numbers of text books, while still pointing the reader to sources of more detailed or specific information.

OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Revised Analysis of Responses Received from Member Countries to the Questionnaire on Data Requirements for Acute Oral Toxicity

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Author :
Publisher : OECD Publishing
ISBN 13 : 9264078436
Total Pages : 53 pages
Book Rating : 4.2/5 (64 download)

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Book Synopsis OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Revised Analysis of Responses Received from Member Countries to the Questionnaire on Data Requirements for Acute Oral Toxicity by : OECD

Download or read book OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Revised Analysis of Responses Received from Member Countries to the Questionnaire on Data Requirements for Acute Oral Toxicity written by OECD and published by OECD Publishing. This book was released on 2002-05-10 with total page 53 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report presents a revised anlaysis of responses received from member countries to the Questionnaire on Data Requirements for Acute Oral Toxicity.

OECD Series on Testing and Assessment Guidance Document 116 on the Conduct and Design of Chronic Toxicity and Carcinogenicity Studies, Supporting Test Guidelines 451, 452 and 453 Second edition

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Author :
Publisher : OECD Publishing
ISBN 13 : 9264221476
Total Pages : 156 pages
Book Rating : 4.2/5 (642 download)

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Book Synopsis OECD Series on Testing and Assessment Guidance Document 116 on the Conduct and Design of Chronic Toxicity and Carcinogenicity Studies, Supporting Test Guidelines 451, 452 and 453 Second edition by : OECD

Download or read book OECD Series on Testing and Assessment Guidance Document 116 on the Conduct and Design of Chronic Toxicity and Carcinogenicity Studies, Supporting Test Guidelines 451, 452 and 453 Second edition written by OECD and published by OECD Publishing. This book was released on 2014-09-03 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: This guidance provides additional information on the conduct of studies performed using Test Guidelines 451, 452 and Test Guideline 453.

OECD Series on Testing and Assessment Guidance Document for the Use of Adverse Outcome Pathways in Developing Integrated Approaches to Testing and Assessment (IATA)

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Author :
Publisher : OECD Publishing
ISBN 13 : 9264891048
Total Pages : 33 pages
Book Rating : 4.2/5 (648 download)

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Book Synopsis OECD Series on Testing and Assessment Guidance Document for the Use of Adverse Outcome Pathways in Developing Integrated Approaches to Testing and Assessment (IATA) by : OECD

Download or read book OECD Series on Testing and Assessment Guidance Document for the Use of Adverse Outcome Pathways in Developing Integrated Approaches to Testing and Assessment (IATA) written by OECD and published by OECD Publishing. This book was released on 2017-03-10 with total page 33 pages. Available in PDF, EPUB and Kindle. Book excerpt: The OECD has been developing guidance documents and tools for the use of alternative methods such as (Q)SAR, chemical categories and Adverse Outcome Pathways (AOPs) as a part of Integrated Approaches for Testing and Assessment (IATA). However, there is a need for a systematic framework to characterise the individual biological and toxicological relevance of alternative methods in assessing chemicals in predicting toxicological endpoints.

OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Guidance Document on the Use of the Harmonised System for the Classification of Chemicals which are Hazardous for the Aquatic Environment

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Author :
Publisher : OECD Publishing
ISBN 13 : 9264078444
Total Pages : 115 pages
Book Rating : 4.2/5 (64 download)

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Book Synopsis OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Guidance Document on the Use of the Harmonised System for the Classification of Chemicals which are Hazardous for the Aquatic Environment by : OECD

Download or read book OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Guidance Document on the Use of the Harmonised System for the Classification of Chemicals which are Hazardous for the Aquatic Environment written by OECD and published by OECD Publishing. This book was released on 2002-05-10 with total page 115 pages. Available in PDF, EPUB and Kindle. Book excerpt: This document provides a description of a Harmonised System for the Classification of Chemicals which are Hazardous for the Aquatic Environment and guidance to how the system will work.

OECD Series on Testing and Assessment The Guidance Document for Using the OECD (Q)SAR Application Toolbox to Develop Chemical Categories According to the OECD Guidance on Grouping Chemicals

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Author :
Publisher : OECD Publishing
ISBN 13 : 9264221484
Total Pages : 118 pages
Book Rating : 4.2/5 (642 download)

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Book Synopsis OECD Series on Testing and Assessment The Guidance Document for Using the OECD (Q)SAR Application Toolbox to Develop Chemical Categories According to the OECD Guidance on Grouping Chemicals by : OECD

Download or read book OECD Series on Testing and Assessment The Guidance Document for Using the OECD (Q)SAR Application Toolbox to Develop Chemical Categories According to the OECD Guidance on Grouping Chemicals written by OECD and published by OECD Publishing. This book was released on 2014-09-03 with total page 118 pages. Available in PDF, EPUB and Kindle. Book excerpt: This document provides guidance on how to use the OECD (Q)SAR Application Toolbox to build chemical categories according to the OECD Guidance on Grouping of Chemicals. It is part of an overall effort to provide guidance on the use of the (Q)SAR Application Toolbox.

OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Guidance Document for the Conduct of Studies of Occupational Exposure to Pesticides During Agricultural Application

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Author :
Publisher : OECD Publishing
ISBN 13 : 926407807X
Total Pages : 57 pages
Book Rating : 4.2/5 (64 download)

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Book Synopsis OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Guidance Document for the Conduct of Studies of Occupational Exposure to Pesticides During Agricultural Application by : OECD

Download or read book OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Guidance Document for the Conduct of Studies of Occupational Exposure to Pesticides During Agricultural Application written by OECD and published by OECD Publishing. This book was released on 2002-05-10 with total page 57 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Guidance Document presents an internationally harmonized approach to the conduct of studies of occupational exposure to pesticides during agricultural application.

OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Guidance Document on Acute Oral Toxicity Testing

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Author :
Publisher : OECD Publishing
ISBN 13 : 926407841X
Total Pages : 24 pages
Book Rating : 4.2/5 (64 download)

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Book Synopsis OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Guidance Document on Acute Oral Toxicity Testing by : OECD

Download or read book OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Guidance Document on Acute Oral Toxicity Testing written by OECD and published by OECD Publishing. This book was released on 2002-05-10 with total page 24 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Guidance Document provides information for both the regulated community and regulators to assist with the choice of the most appropriate Guideline to enable particular data requirements to be met while reducing the number of animals used and animal suffering.

OECD Series on Testing and Assessment Guidance Document on the Reporting of Defined Approaches and Individual Information Sources to be Used within Integrated Approaches to Testing and Assessment (IATA) for Skin Sensitisation

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Author :
Publisher : OECD Publishing
ISBN 13 : 9264279288
Total Pages : 311 pages
Book Rating : 4.2/5 (642 download)

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Book Synopsis OECD Series on Testing and Assessment Guidance Document on the Reporting of Defined Approaches and Individual Information Sources to be Used within Integrated Approaches to Testing and Assessment (IATA) for Skin Sensitisation by : OECD

Download or read book OECD Series on Testing and Assessment Guidance Document on the Reporting of Defined Approaches and Individual Information Sources to be Used within Integrated Approaches to Testing and Assessment (IATA) for Skin Sensitisation written by OECD and published by OECD Publishing. This book was released on 2017-07-11 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: With a view to assisting the evaluation of integrated approaches to testing and assessment (IATA) in regulatory decision-making within OECD Member Countries, this guidance document provides guidance on the reporting of defined approaches to testing and assessment in the area of skin ...

OECD Series on Testing and Assessment Guidance on the Incorporation of Bioavailability Concepts for Assessing the Chemical Ecological Risk and/or Environmental Threshold Values of Metals and Inorganic Metal Compounds

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Publisher : OECD Publishing
ISBN 13 : 9264274839
Total Pages : 85 pages
Book Rating : 4.2/5 (642 download)

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Book Synopsis OECD Series on Testing and Assessment Guidance on the Incorporation of Bioavailability Concepts for Assessing the Chemical Ecological Risk and/or Environmental Threshold Values of Metals and Inorganic Metal Compounds by : OECD

Download or read book OECD Series on Testing and Assessment Guidance on the Incorporation of Bioavailability Concepts for Assessing the Chemical Ecological Risk and/or Environmental Threshold Values of Metals and Inorganic Metal Compounds written by OECD and published by OECD Publishing. This book was released on 2017-04-13 with total page 85 pages. Available in PDF, EPUB and Kindle. Book excerpt: Several models, tools and methods have been published in the past 20 years to include bioavailability in risk assessment and several OECD member countries already have developed frameworks and published guidance documents for taking metal specificities into account in environmental risk ...