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Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 441 Hershberger Bioassay In Rats A Short Term Screening Assay For Antiandrogenic Properties
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Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 441: Hershberger Bioassay in Rats A Short-term Screening Assay for (Anti)Androgenic Properties by : OECD
Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 441: Hershberger Bioassay in Rats A Short-term Screening Assay for (Anti)Androgenic Properties written by OECD and published by OECD Publishing. This book was released on 2009-09-08 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Hershberger Bioassay is an in vivo short–term screening test. It evaluates the ability of a chemical to elicit biological activities consistent with androgen agonists, antagonists or 5 á-reductase inhibitors. The current bioassay is based on the ...
Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 456: H295R Steroidogenesis Assay by : OECD
Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 456: H295R Steroidogenesis Assay written by OECD and published by OECD Publishing. This book was released on 2011-07-28 with total page 27 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline describes an in vitro screen for chemical effects on steroidogenesis, specifically the production of 17ß-estradiol (E2) and testosterone (T). The human H295R adreno-carcinoma cell line, used for the assay, expresses genes that ...
Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 440: Uterotrophic Bioassay in Rodents A short-term screening test for oestrogenic properties by : OECD
Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 440: Uterotrophic Bioassay in Rodents A short-term screening test for oestrogenic properties written by OECD and published by OECD Publishing. This book was released on 2007-10-15 with total page 21 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Uterotrophic Bioassay is an in vivo short-term screening test. It is based on the increase in uterine weight or uterotrophic response. The Uterotrophic Bioassay relies for its sensitivity on an animal test system in which the ...
Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 443: Extended One-Generation Reproductive Toxicity Study by : OECD
Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 443: Extended One-Generation Reproductive Toxicity Study written by OECD and published by OECD Publishing. This book was released on 2018-06-27 with total page 25 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline is designed to provide an evaluation of reproductive and developmental effects that may occur as a result of pre- and postnatal chemical exposure as well as an evaluation of systemic toxicity in pregnant and lactating females and ...
Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 409: Repeated Dose 90-Day Oral Toxicity Study in Non-Rodents by : OECD
Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 409: Repeated Dose 90-Day Oral Toxicity Study in Non-Rodents written by OECD and published by OECD Publishing. This book was released on 1998-09-21 with total page 9 pages. Available in PDF, EPUB and Kindle. Book excerpt: This method provides information on health hazard likely to arise from short-term exposure to test substance. The determination of sub-chronic oral toxicity using repeated doses may be carried out after initial information on toxicity has been ...
Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 424: Neurotoxicity Study in Rodents by : OECD
Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 424: Neurotoxicity Study in Rodents written by OECD and published by OECD Publishing. This book was released on 1997-07-21 with total page 15 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline has been designed to obtain the information necessary to confirm or to further characterise the potential neurotoxicity of chemicals in adult animals. This Test Guideline is designed for use with the rat. It specifically ...
Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 420: Acute Oral Toxicity - Fixed Dose Procedure by : OECD
Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 420: Acute Oral Toxicity - Fixed Dose Procedure written by OECD and published by OECD Publishing. This book was released on 2002-02-08 with total page 14 pages. Available in PDF, EPUB and Kindle. Book excerpt: A principle of the method is that in the main study only moderately toxic doses are used, and the administration of doses that are expected to be lethal should be avoided. This Guideline is intended primarily for use with rat. Groups of animals of a ...
Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 2 Test No. 230: 21-day Fish Assay A Short-Term Screening for Oestrogenic and Androgenic Activity, and Aromatase Inhibition by : OECD
Download or read book OECD Guidelines for the Testing of Chemicals, Section 2 Test No. 230: 21-day Fish Assay A Short-Term Screening for Oestrogenic and Androgenic Activity, and Aromatase Inhibition written by OECD and published by OECD Publishing. This book was released on 2009-09-08 with total page 38 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline describes an in vivo screening assay for certain endocrine active substances where sexually mature male and spawning female fish are held together and exposed to a chemical during a limited part of their life-cycle (21 days ...
Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 408: Repeated Dose 90-Day Oral Toxicity Study in Rodents by : OECD
Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 408: Repeated Dose 90-Day Oral Toxicity Study in Rodents written by OECD and published by OECD Publishing. This book was released on 2018-06-27 with total page 16 pages. Available in PDF, EPUB and Kindle. Book excerpt: This method provides information on health hazard likely to arise from exposure to test substance via oral administration. The determination of sub-chronic oral toxicity using repeated doses may be carried out after initial information on toxicity has been obtained from acute or repeated dose ...
Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 414: Prenatal Developmental Toxicity Study by : OECD
Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 414: Prenatal Developmental Toxicity Study written by OECD and published by OECD Publishing. This book was released on 2018-06-27 with total page 14 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline for developmental toxicity testing is designed to provide general information concerning the effects of prenatal exposure on the pregnant test animal and on the developing organism. The test substance is normally administered to ...
Book Synopsis OECD Guidelines for the Testing of Chemicals / Section 4: Health Effects Summary of Considerations in the Report from the OECD Expert Groups on Short Term and Long Term Toxicology by : OECD
Download or read book OECD Guidelines for the Testing of Chemicals / Section 4: Health Effects Summary of Considerations in the Report from the OECD Expert Groups on Short Term and Long Term Toxicology written by OECD and published by OECD Publishing. This book was released on 2006-09-11 with total page 12 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 479: Genetic Toxicology: In vitro Sister Chromatid Exchange Assay in Mammalian Cells by : OECD
Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 479: Genetic Toxicology: In vitro Sister Chromatid Exchange Assay in Mammalian Cells written by OECD and published by OECD Publishing. This book was released on 1986-10-23 with total page 5 pages. Available in PDF, EPUB and Kindle. Book excerpt: The sister chromatid exchange (SCE) assay is a short-term test for the detection of reciprocal exchanges of DNA between two sister chromatids of a duplicating chromosome. Detection of SCEs requires some means of differentially labeling sister ...
Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 485: Genetic toxicology, Mouse Heritable Translocation Assay by : OECD
Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 485: Genetic toxicology, Mouse Heritable Translocation Assay written by OECD and published by OECD Publishing. This book was released on 1986-10-23 with total page 6 pages. Available in PDF, EPUB and Kindle. Book excerpt: The mouse heritable translocation test detects structural and numerical chromosome changes in mammalian germ cells as recovered in first generation progeny. The types of chromosome changes detected in this test system are reciprocal translocations ...
Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 421: Reproduction/Developmental Toxicity Screening Test by : OECD
Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 421: Reproduction/Developmental Toxicity Screening Test written by OECD and published by OECD Publishing. This book was released on 2016-07-29 with total page 16 pages. Available in PDF, EPUB and Kindle. Book excerpt: This screening Test Guideline describes the effects of a test chemical on male and female reproductive performance.
Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 2 Test No. 251: Rapid Androgen Disruption Activity Reporter (RADAR) assay by : OECD
Download or read book OECD Guidelines for the Testing of Chemicals, Section 2 Test No. 251: Rapid Androgen Disruption Activity Reporter (RADAR) assay written by OECD and published by OECD Publishing. This book was released on 2022-06-30 with total page 44 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Rapid Androgen Disruption Activity Reporter (RADAR) Test Guideline describes an aquatic assay that utilizes transgenic Oryzias latipes (O. latipes, Japanese medaka) eleutheroembryos at day post hatch zero, in a multi-well format to detect chemicals active on the androgen axis.
Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 403: Acute Inhalation Toxicity by : OECD
Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 403: Acute Inhalation Toxicity written by OECD and published by OECD Publishing. This book was released on 2009-09-08 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt: This method provides information on health hazard likely to arise from short-term exposure to a test article (gas, vapour or aerosol/particulate test article) by inhalation. The revised Test Guideline describes two studies: a traditional LC50 ...
Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 402: Acute Dermal Toxicity by : OECD
Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 402: Acute Dermal Toxicity written by OECD and published by OECD Publishing. This book was released on 2017-10-09 with total page 13 pages. Available in PDF, EPUB and Kindle. Book excerpt: This method provides information on health hazard likely to arise from a short-term exposure to solid or liquid test substance by the dermal route. This Test Guideline is intended primarily for use with rodents (rat, rabbit or guinea pig may be ...
