Understanding Risk to Wildlife from Exposures to Per- and Polyfluorinated Alkyl Substances (PFAS)

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Author :
Publisher : CRC Press
ISBN 13 : 1000375862
Total Pages : 177 pages
Book Rating : 4.0/5 (3 download)

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Book Synopsis Understanding Risk to Wildlife from Exposures to Per- and Polyfluorinated Alkyl Substances (PFAS) by : Mark S. Johnson

Download or read book Understanding Risk to Wildlife from Exposures to Per- and Polyfluorinated Alkyl Substances (PFAS) written by Mark S. Johnson and published by CRC Press. This book was released on 2021-04-21 with total page 177 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understanding Risk to Wildlife from Exposures to Per- and Polyfluorinated Alkyl Substances (PFAS) provides the most recent summary of toxicity data relevant to mammals, birds, reptiles, and amphibians, and provides values for use in risk assessment applications. Predicting the bioaccumulation of PFAS in terrestrial wildlife (including humans) has proven to be extremely complex. As a group, PFAS act differently than traditional non-ionic organic molecules, where PFAS can break down and reform, whereas some are demonstrated to be extremely persistent. Where sufficient data are provided, this book establishes toxicity reference values (TRVs), which are derived to assist in characterizing environmental sources of contamination and making risk-based decisions. Features: Provides toxicity reference values (TRVs) for vertebrates (mammals, birds, amphibians) for PFAS, where sufficient data are available, and includes objective supporting background information. Assigns a level of confidence to each TRV to provide the risk assessor with an understanding of the relative uncertainty associated with each value. Presents toxicity data in the formats of scatter diagrams and tables for quick review and assessment. Provides TRVs relevant for screening and decision making This book serves as a useful aid for risk assessors and managers in those industries that have sites contaminated with PFAS, consultants tasked with evaluating risks at such sites, and staff at regulatory agencies at various governmental levels, who need to know how much contamination is considered safe for wildlife. It will also appeal to researchers with an interest in filling the gaps in the current toxicological data for PFAS exposure.

Toxicants in Food Packaging and Household Plastics

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Author :
Publisher : Springer
ISBN 13 : 1447165004
Total Pages : 311 pages
Book Rating : 4.4/5 (471 download)

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Book Synopsis Toxicants in Food Packaging and Household Plastics by : Suzanne M. Snedeker

Download or read book Toxicants in Food Packaging and Household Plastics written by Suzanne M. Snedeker and published by Springer. This book was released on 2014-08-13 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book serves as a comprehensive resource on toxicants that can be released from food packaging materials and household plastics. Chapters include sources and levels of chemical exposure, known and suspected health effects and the identification of data gaps with recommendations for further research. In addition, regulatory approaches and risk assessment challenges in the United States and Europe are discussed. Chapters cover both the more widely known chemicals that can migrate from food packaging (bisphenol A, perfluorinated chemicals), and household plastics (lead, phthalates, brominated flame retardants), as well as chemicals that are just entering use in food packaging (nanomaterials in polymer food packaging) and chemicals recently identified as migrating from food packaging to food stuffs (phthalates, benzophenones, antimony, methylnaphthalene and the alkylphenols nonylphenol and octylphenol). Chapters on phthalates and brominated flame retardants discuss challenges that arise with the use of replacement chemicals. The health effect sections of chapters have drawn on a wide variety of toxicological endpoints and recommend approaches to better assess toxicological risks in vulnerable human populations. Reflecting the global nature of our food supply and household consumer goods, contributions have been drawn from international experts. A wide range of scientists will find this book to be useful, including toxicologists, environmental health scientists, food scientists, and regulators.

Science and Decisions

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Author :
Publisher : National Academies Press
ISBN 13 : 0309120462
Total Pages : 422 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Science and Decisions by : National Research Council

Download or read book Science and Decisions written by National Research Council and published by National Academies Press. This book was released on 2009-03-24 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: Risk assessment has become a dominant public policy tool for making choices, based on limited resources, to protect public health and the environment. It has been instrumental to the mission of the U.S. Environmental Protection Agency (EPA) as well as other federal agencies in evaluating public health concerns, informing regulatory and technological decisions, prioritizing research needs and funding, and in developing approaches for cost-benefit analysis. However, risk assessment is at a crossroads. Despite advances in the field, risk assessment faces a number of significant challenges including lengthy delays in making complex decisions; lack of data leading to significant uncertainty in risk assessments; and many chemicals in the marketplace that have not been evaluated and emerging agents requiring assessment. Science and Decisions makes practical scientific and technical recommendations to address these challenges. This book is a complement to the widely used 1983 National Academies book, Risk Assessment in the Federal Government (also known as the Red Book). The earlier book established a framework for the concepts and conduct of risk assessment that has been adopted by numerous expert committees, regulatory agencies, and public health institutions. The new book embeds these concepts within a broader framework for risk-based decision-making. Together, these are essential references for those working in the regulatory and public health fields.

Toxicity Assessment

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Author :
Publisher :
ISBN 13 : 9781071610916
Total Pages : 266 pages
Book Rating : 4.6/5 (19 download)

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Book Synopsis Toxicity Assessment by : Carlos M. Palmeira

Download or read book Toxicity Assessment written by Carlos M. Palmeira and published by . This book was released on 2021 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book collects protocols from different areas of knowledge to assist in the identification of toxic effects exerted by different xenobiotics. At the same time as classical techniques are presented, modern techniques with alternative models to the use of animals are also presented. Given the ever-increasing exposure to different compounds and their effects on population health, the assessment of multiple endpoints is of utmost importance for better risk assessment, and this collection addresses that need. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Toxicity Assessment: Methods and Protocols aims to serve researchers in this vast field of science as they seek to better understand the mechanisms of action of different xenobiotics.

Fluorinated Surfactants and Repellents, Second Edition,

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Author :
Publisher : CRC Press
ISBN 13 : 9780824704728
Total Pages : 650 pages
Book Rating : 4.7/5 (47 download)

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Book Synopsis Fluorinated Surfactants and Repellents, Second Edition, by : Erik Kissa

Download or read book Fluorinated Surfactants and Repellents, Second Edition, written by Erik Kissa and published by CRC Press. This book was released on 2001-02-09 with total page 650 pages. Available in PDF, EPUB and Kindle. Book excerpt: A discussion of the synthesis, problems, theories and applications of fluorinated surfactants, this second edition is updated with four new chapters on repellency and protection against soiling and staining and over 2900 references, equations, and drawings (800 more than the previous edition). It lists alphabetically and explores numerous applications of fluorinated surfactants. Called "...a most useful introduction to these fascinating materials" by the Journal of Dispersion Science and Technology and "...a coherent and stimulating handbook...the most useful book in the fluorinated surfactants field to date. Recommended." by the Journal of the Chemical Society, Faraday Transactions - this book is a source of factual data, methods of manufacture, and chemical structures for the surfactant scientist and user.

Polyfluorinated Chemicals and Transformation Products

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3642218717
Total Pages : 183 pages
Book Rating : 4.6/5 (422 download)

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Book Synopsis Polyfluorinated Chemicals and Transformation Products by : Thomas P. Knepper

Download or read book Polyfluorinated Chemicals and Transformation Products written by Thomas P. Knepper and published by Springer Science & Business Media. This book was released on 2011-09-21 with total page 183 pages. Available in PDF, EPUB and Kindle. Book excerpt: Due to their unparalleled effectiveness and efficiency, polyfluorinated chemicals (PFC) have become essential in numerous technical applications. However, many PFCs brought to market show limited biodegradability, and their environmental persistence combined with toxic and bioaccumulative potential have become a matter of concern in some instances. This volume highlights the synthesis of PFCs, focusing on substances with improved application and environmental properties, which are a challenge for synthetic chemists. Further, modern mass spectrometric techniques for the detection and identification of biotransformation products of PFCs are described. The sorption and leaching behavior of PFC in soil is also addressed in order to predict their fate in the environment. Several contributions discuss the monitoring of PFCs in European surface, ground and drinking waters, treatment options for PFC removal from drinking water, occurrence in food, and the human biomonitoring of PFCs.

Perfluorinated Chemicals (PFCs)

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1119363837
Total Pages : 271 pages
Book Rating : 4.1/5 (193 download)

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Book Synopsis Perfluorinated Chemicals (PFCs) by : Nicholas P. Cheremisinoff

Download or read book Perfluorinated Chemicals (PFCs) written by Nicholas P. Cheremisinoff and published by John Wiley & Sons. This book was released on 2016-11-29 with total page 271 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new volume provides a timely study on the environmental challenges from a specific class of perfluorinated chemical compounds (PFCs) that are now being recognized as a worldwide health threat. Recent studies report that levels of classes of PFCs known as polyfluoroalkyl and perfluoroalkyl (PFASs) exceed federally recommended safety levels in public drinking-water supplies for 6 million people in the United States and that as many as 100 million people could be at risk from exposure to these chemicals. These chemicals occur globally in wildlife and humans. Both PFCAs and PFSAs have been produced for more than 50 years, but have only become of interest to regulators and environmentalists since the late 1990s. Recent advances in analytical methodology has enabled widespread detection in the environment and humans at trace levels. These toxic chemicals have been found in outdoor and indoor air, surface and drinking water, house dust, animal tissue, human blood serum, and human breast milk. Of great concern to communities is the presence of these compounds in a number of drinking water supplies in the U.S. and other countries. This new volume provides a timely explanation of the chemicals, provides a detailed review of the regulations both in the US and European Community, explains the health risk literature, and then explores in great detail available treatment technologies. The volume is a must for public water supply facilities, industrial operations that have historically used these chemicals and face legacy pollution issues, policy makers and the general public.

Toxicological Effects of Perfluoroalkyl and Polyfluoroalkyl Substances

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Author :
Publisher : Humana Press
ISBN 13 : 3319155180
Total Pages : 500 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Toxicological Effects of Perfluoroalkyl and Polyfluoroalkyl Substances by : Jamie C. DeWitt

Download or read book Toxicological Effects of Perfluoroalkyl and Polyfluoroalkyl Substances written by Jamie C. DeWitt and published by Humana Press. This book was released on 2015-04-14 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book serves as a timely and comprehensive overview of the latest science for perfluoroalkyl and polyfluoroalkyl substances (PFASs), covering the development of methods for assessing PFASs in biological fluids and tissues as well as the current knowledge regarding their toxicity to vertebrate organisms. This book includes chapters on human and wildlife exposure/body burdens, reviews of metabolism and toxicological effects by organ system/developmental stage and aspects of PFAS toxicity that are driving PFAS research and regulatory oversight. Toxicological Effects of Perfluoroalkyl and Polyfluoroalkyl Substances provide critical assessments of the most controversial topics surrounding toxicological evaluation of PFASs to give readers an expert perspective on the issues. Emphasis is placed on the integration of modes and mechanisms of action with functional endpoints that are relevant to human and wildlife health. This book will be a useful resource for toxicologists, environmental chemists, risk assessors and researchers with an interest in the class of compounds known as perfluoroalkyl and polyfluoroalkyl substances.

Reviews of Environmental Contamination and Toxicology Volume 213

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1441998608
Total Pages : 176 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Reviews of Environmental Contamination and Toxicology Volume 213 by : David M. Whitacre

Download or read book Reviews of Environmental Contamination and Toxicology Volume 213 written by David M. Whitacre and published by Springer Science & Business Media. This book was released on 2011-05-04 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reviews of Environmental Contamination and Toxicology attempts to provide concise, critical reviews of timely advances, philosophy and significant areas of accomplished or needed endeavor in the total field of xenobiotics, in any segment of the environment, as well as toxicological implications.

Toxicological Profile for Perfluoroalkyls

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Publisher :
ISBN 13 :
Total Pages : 412 pages
Book Rating : 4.:/5 (9 download)

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Book Synopsis Toxicological Profile for Perfluoroalkyls by :

Download or read book Toxicological Profile for Perfluoroalkyls written by and published by . This book was released on 2009 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This toxicological profile for perfluoroalkyls was prepared consistent with guidelines developed by the Agency for Toxic Substances and Disease Registry (ATSDR) and the Environmental Protection Agency (EPA) for the preparation of toxicological profiles. The original guidelines were published in the Federal Register on April 17, 1987. While Perfluoroalkyls are not found on the ATSDR list of Priority Hazardous Substances, ATSDR has determined that a profile for these substances was necessary because data indicate that some perfluoroalkyls are found in the blood of the U.S. general population and in the environment. The agency also determined that it was important to characterize the current available information regarding the health effects from exposure in order to support and inform public health responses and activities by ATSDR and other." -- p. v

Principles of Route-to-route Extrapolation for Risk Assessment

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Author :
Publisher : Elsevier Publishing Company
ISBN 13 : 9780444015822
Total Pages : 322 pages
Book Rating : 4.0/5 (158 download)

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Book Synopsis Principles of Route-to-route Extrapolation for Risk Assessment by : Timothy R. Gerrity

Download or read book Principles of Route-to-route Extrapolation for Risk Assessment written by Timothy R. Gerrity and published by Elsevier Publishing Company. This book was released on 1990 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Preparation, Properties, and Industrial Applications of Organofluorine Compounds

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Author :
Publisher : Ellis Horwood
ISBN 13 :
Total Pages : 360 pages
Book Rating : 4.:/5 (44 download)

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Book Synopsis Preparation, Properties, and Industrial Applications of Organofluorine Compounds by : Ronald Eric Banks

Download or read book Preparation, Properties, and Industrial Applications of Organofluorine Compounds written by Ronald Eric Banks and published by Ellis Horwood. This book was released on 1982 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt:

National Report on Human Exposure to Environmental Chemicals

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Publisher :
ISBN 13 :
Total Pages : 266 pages
Book Rating : 4.:/5 (7 download)

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Book Synopsis National Report on Human Exposure to Environmental Chemicals by :

Download or read book National Report on Human Exposure to Environmental Chemicals written by and published by . This book was released on 2003 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Perfluoroalkyl Substances in the Environment

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Publisher : CRC Press
ISBN 13 : 0429945027
Total Pages : 495 pages
Book Rating : 4.4/5 (299 download)

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Book Synopsis Perfluoroalkyl Substances in the Environment by : David M. Kempisty

Download or read book Perfluoroalkyl Substances in the Environment written by David M. Kempisty and published by CRC Press. This book was released on 2018-08-06 with total page 495 pages. Available in PDF, EPUB and Kindle. Book excerpt: Per- and polyfluorinated alkyl substances (PFAS), often referred to as per- (and poly) fluorinated compounds (PFCs), have been used for years in many everyday3⁄4 and some lifesaving3⁄4 products. However, their use has been linked to adverse health effects in humans, a problem compounded by their persistence in the environment. This book discusses the various challenges of PFAS in our environment today, including their historical use as well as their chemical and toxicological properties. It also presents robust discussion of analytical challenges and special considerations in sampling. The work goes on to give practical recommendations for dealing with these compounds in today's dynamic regulatory landscape and includes several chapters on various remediation techniques. Key Features: Comprehensive overview of per- and polyfluorinated alkyl substances (PFAS) historical use and chemical/physical properties which help us understand their persistence, transport, and transformation pathways in the environment In-depth analysis of PFAS toxicology Detailed descriptions of conventional and state-of-the-art remediation technologies Practical recommendations for dealing with PFAS in a dynamic regulatory landscape Robust discussion of important sampling and analytical considerations Perfluoroalkyl Substances in the Environment: Theory, Practice, and Innovation explores the challenges across the topical areas of regulation and management, toxicology, environmental remediation, and analytical sampling and analysis.Readers will find this text helpful in understanding complexities associated with PFAS and informing management strategies to effectively protect this and future generations.

Methods to Assess DNA Damage and Repair

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Author :
Publisher :
ISBN 13 :
Total Pages : 300 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis Methods to Assess DNA Damage and Repair by : Robert G. Tardiff

Download or read book Methods to Assess DNA Damage and Repair written by Robert G. Tardiff and published by . This book was released on 1994-08-16 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Integrates data obtained from a variety of disciplines to evaluate the current state of knowledge regarding defense mechanisms and applies this information to estimate health risks to humans exposed to substances that alter genetic material. Recognized experts document, to a large extent, which carcinogens can cause injury to human beings and their surroundings, providing guidance for the structured acquisition of key information to reduce cancer risks throughout the environment.

Dermal Exposure

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Author :
Publisher : Environmental Health Criteria
ISBN 13 : 9789241572422
Total Pages : 0 pages
Book Rating : 4.5/5 (724 download)

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Book Synopsis Dermal Exposure by : World Health Organization

Download or read book Dermal Exposure written by World Health Organization and published by Environmental Health Criteria. This book was released on 2014 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "IPCS, International Programme on Chemical Safety."