Novel Strategies Targeting Obesity And Metabolic Diseases Volume Ii

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Novel Strategies Targeting Obesity and Metabolic Diseases, Volume II

Author : Xinran Ma
Publisher : Frontiers Media SA
ISBN 13 : 2832544495
Total Pages : 126 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Novel Strategies Targeting Obesity and Metabolic Diseases, Volume II by : Xinran Ma

Download or read book Novel Strategies Targeting Obesity and Metabolic Diseases, Volume II written by Xinran Ma and published by Frontiers Media SA. This book was released on 2024-02-08 with total page 126 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Research Topic is part of the Novel Strategies Targeting Obesity and Metabolic Diseases series (Volume I). The 21st century features excessive food availability and prevalent sedentary lifestyle. Unsurprisingly, obesity has become one of the most serious problems threatening public health with a staggering morbidity/mortality rate. Obesity is the leading risk factor for a series of metabolic diseases, i.e. diabetes, cardiovascular disease, hypertension, non-alcoholic hepatic steatosis, osteoporosis and certain types of cancer. Although, theoretically, body weight could be easily controlled by the balance of food intake and caloric burning, the rapid and stressful pace of modern society has made the healthy life style of eating less and exercising more hard to achieve its popularity. Pharmacotherapeutic solutions targeting appetite or energy expenditure are limited and often with undesired and sometimes dangerous side effects. The problem becomes even more complicated when genetic susceptibility for obesity is taken into account. In result, till now, the long and intense battle for obesity-intervention still wages and we are in urgent need for effective weight-losing strategies.

Novel Strategies Targeting Obesity and Metabolic Diseases

Author : Xinran Ma
Publisher : Frontiers Media SA
ISBN 13 : 2889630412
Total Pages : 169 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Novel Strategies Targeting Obesity and Metabolic Diseases by : Xinran Ma

Download or read book Novel Strategies Targeting Obesity and Metabolic Diseases written by Xinran Ma and published by Frontiers Media SA. This book was released on 2019-10-09 with total page 169 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Disease Control Priorities, Third Edition (Volume 5)

Author : Dorairaj Prabhakaran
Publisher : World Bank Publications
ISBN 13 : 1464805202
Total Pages : 948 pages
Book Rating : 4.4/5 (648 download)

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Book Synopsis Disease Control Priorities, Third Edition (Volume 5) by : Dorairaj Prabhakaran

Download or read book Disease Control Priorities, Third Edition (Volume 5) written by Dorairaj Prabhakaran and published by World Bank Publications. This book was released on 2017-11-17 with total page 948 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiovascular, respiratory, and related conditions cause more than 40 percent of all deaths globally, and their substantial burden is rising, particularly in low- and middle-income countries (LMICs). Their burden extends well beyond health effects to include significant economic and societal consequences. Most of these conditions are related, share risk factors, and have common control measures at the clinical, population, and policy levels. Lives can be extended and improved when these diseases are prevented, detected, and managed. This volume summarizes current knowledge and presents evidence-based interventions that are effective, cost-effective, and scalable in LMICs.

Nutritional and Therapeutic Interventions for Diabetes and Metabolic Syndrome

Author : Debasis Bagchi
Publisher : Academic Press
ISBN 13 : 0123850835
Total Pages : 553 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis Nutritional and Therapeutic Interventions for Diabetes and Metabolic Syndrome by : Debasis Bagchi

Download or read book Nutritional and Therapeutic Interventions for Diabetes and Metabolic Syndrome written by Debasis Bagchi and published by Academic Press. This book was released on 2012-01-31 with total page 553 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diabetes mellitus affects approximately 20 million people in the US, or nearly 7% of the population. It is expected to increase by 70% within the next 25 years, and numerous epidemiologic studies have demonstrated that type 2 diabetes increases the risk of cardiovascular morbidity and mortality. It is estimated to cost over $92 billion in health care costs and lost productivity. The increased risk is due to the detrimental vascular effects of prolonged exposure to a hyperglycemic, oxidant-rich environment yielding associated cardiovascular risk factors: atherosclerosis, hypertension and clotting abnormalities. Hypertension and dyslipidemia in diabetic patients produces substantial decreases in cardiovascular and microvascular diseases. Nutritional and Therapeutic Interventions for Diabetes and Metabolic Syndrome provides an overview of the current epidemic, outlines the consequences of this crisis and lays out strategies to forestall and prevent diabetes, obesity and other intricate issues of metabolic syndrome. The contributing experts from around the world give this book relevant and up-to-date global approaches to the critical consequences of metabolic syndrome and make it an important reference for those working with the treatment, evaluation or public health planning for the effects of metabolic syndrome and diabetes. Scientific discussion of the epidemiology and pathophysiology of the relationship between diabetes and metabolic syndrome Includes coverage of Pre-diabetes conditions plus both Type I and Type II Diabetes Presents both prevention and treatment options

Cancer as a Metabolic Disease

Author : Thomas Seyfried
Publisher : John Wiley & Sons
ISBN 13 : 1118310306
Total Pages : 482 pages
Book Rating : 4.1/5 (183 download)

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Book Synopsis Cancer as a Metabolic Disease by : Thomas Seyfried

Download or read book Cancer as a Metabolic Disease written by Thomas Seyfried and published by John Wiley & Sons. This book was released on 2012-05-18 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book addresses controversies related to the origins of cancer and provides solutions to cancer management and prevention. It expands upon Otto Warburg's well-known theory that all cancer is a disease of energy metabolism. However, Warburg did not link his theory to the "hallmarks of cancer" and thus his theory was discredited. This book aims to provide evidence, through case studies, that cancer is primarily a metabolic disease requring metabolic solutions for its management and prevention. Support for this position is derived from critical assessment of current cancer theories. Brain cancer case studies are presented as a proof of principle for metabolic solutions to disease management, but similarities are drawn to other types of cancer, including breast and colon, due to the same cellular mutations that they demonstrate.

Obesity Prevention and Treatment

Author : James M. Rippe
Publisher : CRC Press
ISBN 13 : 1000456625
Total Pages : 236 pages
Book Rating : 4.0/5 (4 download)

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Book Synopsis Obesity Prevention and Treatment by : James M. Rippe

Download or read book Obesity Prevention and Treatment written by James M. Rippe and published by CRC Press. This book was released on 2021-09-23 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: The World Health Organization estimates that there are 2.1 billion individuals with obesity globally. Nearly three quarters of adults in the United States are overweight or obese. The average individual with obesity cuts ten years off their life expectancy, yet less than 40% of physicians routinely counsel individuals concerning the adverse health consequences of obesity. Obesity Prevention and Treatment: A Practical Guide equips healthcare practitioners to include effective weight management counselling in the daily practice of medicine. Written by lifestyle medicine pioneer and cardiologist, Dr. James Rippe and obesity expert Dr. John Foreyt, this book provides evidence-based discussions of obesity and its metabolic consequences. A volume in the Lifestyle Medicine Series, it provides evidence-based information about the prevention and treatment of obesity through lifestyle measures, such as regular physical activity and sound nutrition, as well as the use of new medications or bariatric surgery available to assist in weight management. Provides a framework and practical strategies to assist practitioners in safe and effective treatments of obesity. Contains information explaining the relationship between obesity and increased risk of heart disease, diabetes, cancer, osteoarthritis, and other chronic conditions. Chapters begin with bulleted key points and conclude with a list of Clinical Applications. Written for practitioners at all levels, this user-friendly, evidence-based book on obesity prevention and treatment will be valuable to practitioners in general medicine or subspecialty practices.

Metabolic Diseases

Author : E. Gilbert-Barness
Publisher : IOS Press
ISBN 13 : 1614997187
Total Pages : 960 pages
Book Rating : 4.6/5 (149 download)

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Book Synopsis Metabolic Diseases by : E. Gilbert-Barness

Download or read book Metabolic Diseases written by E. Gilbert-Barness and published by IOS Press. This book was released on 2017-01-06 with total page 960 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 2nd Edition of Metabolic Diseases provides readers with a completely updated description of the Foundations of Clinical Management, Genetics, and Pathology. A distinguished group of 31 expert authors has contributed 25 chapters as a tribute to Enid Gilbert-Barness and the late Lewis Barness--- both pioneers in this topic. Enid’s unique perspectives on the pathology of genetic disorders and Lew’s unsurpassed knowledge of metabolism integrated with nutrition have inspired the contributors to write interdisciplinary descriptions of generally rare, and always challenging, hereditary metabolic disorders. Discussions of these interesting genetic disorders are organized in the perspective of molecular abnormalities leading to morphologic disturbances with distinct pathology and clinical manifestations. The book emphasizes recent advances such as development of improved diagnostic methods and discovery of new, more effective therapies for many of the diseases. It includes optimal strategies for diagnosis and information on access to specialized laboratories for specific testing. The target audience is a wide variety of clinicians, including pediatricians, neonatologists, obstetricians, maternal-fetal specialists, internists, pathologists, geneticists, and laboratorians engaged in prenatal and/or neonatal screening. In addition, all scientists and health science professionals interested in metabolic diseases will find the comprehensive, integrated chapters informative on the latest discoveries. It is our hope that the 2nd Edition will open new avenues and vistas for our readers and that they will share with us the interest, excitement and passion of the research into all these challenging disorders.

Diabetes, hypertension and cardiovascular diseases, volume II

Author : Soo-Kyoung Choi
Publisher : Frontiers Media SA
ISBN 13 : 283251426X
Total Pages : 145 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Diabetes, hypertension and cardiovascular diseases, volume II by : Soo-Kyoung Choi

Download or read book Diabetes, hypertension and cardiovascular diseases, volume II written by Soo-Kyoung Choi and published by Frontiers Media SA. This book was released on 2023-02-10 with total page 145 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Global Perspectives on Childhood Obesity

Author : Debasis Bagchi
Publisher : Academic Press
ISBN 13 : 0128128410
Total Pages : 506 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Global Perspectives on Childhood Obesity by : Debasis Bagchi

Download or read book Global Perspectives on Childhood Obesity written by Debasis Bagchi and published by Academic Press. This book was released on 2019-02-06 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: Global Perspectives on Childhood Obesity: Current Status, Consequences and Prevention, Second Edition examines the current childhood obesity epidemic, outlines the consequences of this crisis, and develops strategies to forestall and prevent it. This book provides a thorough investigation of the causes of childhood obesity and, more importantly, offers specific prevention strategies that can be used by medical and mental health professionals, policymakers, community organizers, and individuals. New chapters on BMI and cardiovascular disease, exercise, neurotransmitters, neurocognition, nutrigenomics and combined prevention strategies are included, making this a solid introduction on the childhood obesity crisis. Researchers, practitioners, and advanced students in public health, health policy, and health economics, as well those working in medicine, pharmacy, nutrition, school health, physiology, and neuroscience related to obesity will find this to be a comprehensive resource. Covers the multifaceted factors contributing to the rapidly growing childhood obesity epidemic Includes new chapters on BMI and cardiovascular disease, exercise, neurotransmitters, self-regulation, and prevention strategies Examines strategies for childhood obesity prevention and treatment, such as physical activity and exercise, personalized nutrition plans, and school and community involvement

Polypharmacology

Author : Zhiguo Wang
Publisher : Springer Nature
ISBN 13 : 3031049985
Total Pages : 870 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Polypharmacology by : Zhiguo Wang

Download or read book Polypharmacology written by Zhiguo Wang and published by Springer Nature. This book was released on 2022-08-01 with total page 870 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is a growing interest in unmet needs for the development of a new discipline in drug discovery and in university education on polypharmacology. However, there has not been a book with the comprehensive compilation of basic knowledge and advanced methodology that is needed. This book aims to meet the needs making Polypharmacology a new sub-discipline of Pharmacology, not only being a hot area of pharmacological research and education but also a new paradigm for drug discovery. It contains the contents covering the entire scope of Polypharmacology including systemic in-depth exposition of basic knowledge, novel concepts, innovative technologies, and translational and clinical applications by showcasing state-of-the-art strategies and step-by-step instructions of cutting-edge methods. The contents of this book targets broad readerships including scientists in pharmacology research and drug development, and university teachers and graduates in medical school or school of pharmacy.

Myc as a Disease Target Beyond Cancer

Author : Jonathan R. Whitfield
Publisher : Frontiers Media SA
ISBN 13 : 2832553958
Total Pages : 216 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Myc as a Disease Target Beyond Cancer by : Jonathan R. Whitfield

Download or read book Myc as a Disease Target Beyond Cancer written by Jonathan R. Whitfield and published by Frontiers Media SA. This book was released on 2024-09-02 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: Myc is a pleiotropic transcription factor fundamental for many cellular processes. It is an infamous and highly-studied oncogene, with around 10,000 articles published in the last decade. The majority of these link it to cancer. The focus on Myc as a hot target in cancer has led to immense efforts – from academia through to pharmaceutical companies – being directed towards finding a Myc inhibitor. Not surprisingly, given its fundamental nature in many physiological processes, Myc has also been linked to a large variety of pathologies other than cancer. The growing efforts to develop Myc inhibitors as cancer therapies will have important implications for the treatment of these diseases too, whether they have a clearly-demonstrated aetiology linked with Myc, or so far are only at early stages of association with it. Interestingly, the activation of Myc may also prove helpful in the field of regenerative medicine and reversal of ageing. The aim of this Research Topic is therefore to describe non-oncological pathologies and conditions to which Myc modulation could be applied. These will include conditions that have strong links to Myc and where Myc modulation has already been modelled, as well as conditions that so far have more limited data linking them to Myc but where it seems to have a key role. Authors will be expected to briefly review the particular disease and what is known to link Myc to it, plus the possibility of any clinical trials in the near future

Chronic Inflammation

Author : Masayuki Miyasaka
Publisher : Springer
ISBN 13 : 4431560688
Total Pages : 679 pages
Book Rating : 4.4/5 (315 download)

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Book Synopsis Chronic Inflammation by : Masayuki Miyasaka

Download or read book Chronic Inflammation written by Masayuki Miyasaka and published by Springer. This book was released on 2016-11-01 with total page 679 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides readers with the most up-to-date information on cutting-edge research concerning chronic inflammation. We now know that when inflammation becomes chronic, it acts as a strong disease-promoting factor in a variety of disorders including arteriosclerosis, obesity, cancer, and Alzheimer disease. Chronic inflammation is hence called as the “silent killer”; it upsets the body’s homeostatic mechanism insidiously. In spite of these developments, we know very little about the mechanism underlying chronic inflammation. Particularly, we do not know precisely what induces chronic inflammation or what promotes its prolongation in a spatiotemporal framework. Neither do we have clear knowledge about how chronic inflammation destroys various tissues or how it predisposes individuals to many different diseases. To make the situation worse, we have no effective treatment against chronic inflammation. Since 2010, two major research programs (CREST and PRESTO) aimed at clarifying the mechanisms underlying chronic inflammation were launched in Japan, and investigators of different research areas with a brilliant track record were selected by their research proposals. Subsequently they have made their best efforts to answer the conundrum concerning chronic inflammation. This book is a compendium of such research efforts. In each chapter, the CREST- or PRESTO-funded researchers summarize their original work concerning mechanisms of induction, progression, or resolution underlying chronic inflammation. The most emphasized characteristic is the molecular aspect of chronic inflammation. The book thus presents the most recent progress made in the molecular understanding of chronic inflammation.

Double-edged Swords: Genetic Factors That Influence the Pathogenesis of Both Metabolic Disease and Cancer

Author : Che-Pei Kung
Publisher : Frontiers Media SA
ISBN 13 : 2889630307
Total Pages : 130 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Double-edged Swords: Genetic Factors That Influence the Pathogenesis of Both Metabolic Disease and Cancer by : Che-Pei Kung

Download or read book Double-edged Swords: Genetic Factors That Influence the Pathogenesis of Both Metabolic Disease and Cancer written by Che-Pei Kung and published by Frontiers Media SA. This book was released on 2019-09-23 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metabolic diseases and cancers account for half of all mortalities in the world, underscoring the significance of understanding the etiology of these diseases and developing effective therapies. Genomic research in the 21st century has brought cancer and metabolic disease, two once seemingly parallel ailments, as close to each other as they’ve ever been. Many genetic factors have been found to display functions regulating both cancer and metabolic disease. In this research topic: "Double-edged Swords: Genetic Factors That Influence The Pathogenesis of Both MetabolicDisease and Cancer", you will be introduced to individual genes, as well as genetic pathways that play important roles in influencing the progression of both metabolic disease and cancer. By no means covering an exhaustive list of genes qualified, this collection of articles rather serves as a precursor of what is yet to come in biomedical research. It paints the big picture of one of the major fields contributing to the future of “precision medicine”.

Drug Delivery Systems for Metabolic Disorders

Author : Harish Dureja
Publisher : Academic Press
ISBN 13 : 0323996337
Total Pages : 527 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Drug Delivery Systems for Metabolic Disorders by : Harish Dureja

Download or read book Drug Delivery Systems for Metabolic Disorders written by Harish Dureja and published by Academic Press. This book was released on 2022-08-26 with total page 527 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug Delivery Systems for Metabolic Disorders presents the most recent developments on the targeted delivery of drugs to deal with metabolic disorders in a safe, compliant and continuous way. The book covers recent developments in advanced drug delivery systems in various metabolic disorders, including disturbances in protein, lipid, carbohydrate and hormone metabolism and lysosomal and mitochondrial disorders. It provides a brief introduction to metabolic disorders, along with a focus on the current landscape and trends in understanding disease pathology using different in vitro and in vivo models required for clinical applications and developments of new therapeutics. Each subsequent chapter covers drug delivery systems dedicated to metabolic diseases caused by disturbances in protein, lipid, carbohydrate and hormone metabolism. Then, it moves on to cover lysosomal storage disorders and applications of phytopharmaceuticals in this context. This is the perfect reference for researchers in pharmaceutical science who are interested in developing new treatments for metabolic diseases. Offers comprehensive coverage of drug delivery to treat metabolic diseases Provides insights into how advanced drug delivery systems can be effectively used for the management of various types of metabolic disorders Includes the most recent research on diagnostic methods and treatment strategies using controlled drug delivery systems

Novel Therapeutic Approaches Targeting Oxidative Stress

Author : Pawan Kumar Maurya
Publisher : Academic Press
ISBN 13 : 032390906X
Total Pages : 294 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Novel Therapeutic Approaches Targeting Oxidative Stress by : Pawan Kumar Maurya

Download or read book Novel Therapeutic Approaches Targeting Oxidative Stress written by Pawan Kumar Maurya and published by Academic Press. This book was released on 2022-02-18 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: Novel Therapeutic Approaches Targeting Oxidative Stress investigates the role of oxidative stress in disease and explores the latest methods and approaches to targeting oxidative stress for treatment and diagnosis. The book begins with an introduction to oxidative stress and its significance. Subsequent sections cover biochemical methods for detecting free radicals and novel therapeutic approaches for targeting oxidative stress in a number of different diseases. This includes age-related illnesses, neuropsychiatric disorders such as schizophrenia and bipolar disorder, and neurodegenerative diseases like Alzheimer’s and Parkinson’s disease. Novel approaches for targeting oxidative stress in cancer and cardiovascular diseases are also explored. The book then moves on to discuss advances in drug delivery systems and detecting oxidative stress biomarkers using biosensors. It concludes with case studies that illustrate the targeting of oxidative stress and future perspectives. Explores oxidative stress in a variety of diseases, including neurological disorders, cardiovascular diseases, age-related diseases, and cancer Covers a range of therapeutic approaches to target oxidative stress Includes chapters on the application of novel drug delivery systems and diagnostic biosensors to oxidative stress Features case studies illustrating the targeting of oxidative stress

Physiology and Physiopathology of Adipose Tissue

Author : Jean-Philippe Bastard
Publisher : Springer Science & Business Media
ISBN 13 : 2817803434
Total Pages : 432 pages
Book Rating : 4.8/5 (178 download)

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Book Synopsis Physiology and Physiopathology of Adipose Tissue by : Jean-Philippe Bastard

Download or read book Physiology and Physiopathology of Adipose Tissue written by Jean-Philippe Bastard and published by Springer Science & Business Media. This book was released on 2012-11-28 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: The scientific advances in the physiology and pathophysiology of adipose tissue over the last two decades have been considerable. Today, the cellular and molecular mechanisms of adipogenesis are well known. In addition, adipose tissue is now recognized as a real endocrine organ that produces hormones such as the leptin acting to regulate food intake and energy balance in the central nervous system, a finding that has completely revolutionized the paradigm of energy homeostasis. Other adipokines have now been described and these molecules are taking on increasing importance in physiology and pathophysiology. Moreover, numerous works have shown that in obesity, but also in cases of lipodystophy, adipose tissue was the site of a local low-grade inflammation that involves immune cells such as macrophages and certain populations of lymphocytes. This new information is an important step in the pathophysiology of both obesity and related metabolic and cardiovascular complications. Finally, it is a unique and original work focusing on adipose tissue, covering biology and pathology by investigating aspects of molecular and cellular biology, general, metabolic, genetic and genomic biochemistry.

Weighing the Options

Author : Paul R. Thomas
Publisher : National Academies
ISBN 13 :
Total Pages : 44 pages
Book Rating : 4.1/5 (419 download)

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Book Synopsis Weighing the Options by : Paul R. Thomas

Download or read book Weighing the Options written by Paul R. Thomas and published by National Academies. This book was released on 1995-03-01 with total page 44 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume presents criteria for evaluating treatment programs for obesity and explores what these criteria mean--to health care providers, program designers, researchers, and even overweight people seeking help. Discusses information necessary to make wise program choices and evaluations; examines how client demographics and characteristics--including health status, knowledge of weight-loss issues, and attitude toward weight and body image--affect these programs.