Novel Approaches for the Delivery of Anti-HIV Drugs

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Author :
Publisher : MDPI
ISBN 13 : 3039219006
Total Pages : 208 pages
Book Rating : 4.0/5 (392 download)

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Book Synopsis Novel Approaches for the Delivery of Anti-HIV Drugs by : José das Neves

Download or read book Novel Approaches for the Delivery of Anti-HIV Drugs written by José das Neves and published by MDPI. This book was released on 2020-05-20 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: HIV/AIDS continues to be one of the most challenging individual and public health concerns of the present day. According to the UNAIDS, nearly 38 million individuals were living with the infection by the end of 2018, while 1.7 million new cases occurred during that same year. In spite of the numerous advances in the development and delivery of antiretroviral agents, both for treatment and prevention, several challenges remain. This book includes original research and review articles on innovative strategies and approaches for the formulation and delivery of anti-HIV drugs, including genetic material and other biopharmaceuticals. Different local and systemic delivery strategies are addressed based on different technologies intended for oral, transdermal, subcutaneous, vaginal, or rectal administration. Authored by eminent scientists in academia and nonprofit organizations involved in the development of antiretroviral drug products, this collection provides useful information for all those involved in HIV/AIDS treatment and prevention.

Novel Approaches for the Delivery of Anti-HIV Drugs

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Author :
Publisher :
ISBN 13 : 9783039219018
Total Pages : 208 pages
Book Rating : 4.2/5 (19 download)

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Book Synopsis Novel Approaches for the Delivery of Anti-HIV Drugs by : José das Neves

Download or read book Novel Approaches for the Delivery of Anti-HIV Drugs written by José das Neves and published by . This book was released on 2020 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: HIV/AIDS continues to be one of the most challenging individual and public health concerns of the present day. According to the UNAIDS, nearly 38 million individuals were living with the infection by the end of 2018, while 1.7 million new cases occurred during that same year. In spite of the numerous advances in the development and delivery of antiretroviral agents, both for treatment and prevention, several challenges remain. This book includes original research and review articles on innovative strategies and approaches for the formulation and delivery of anti-HIV drugs, including genetic material and other biopharmaceuticals. Different local and systemic delivery strategies are addressed based on different technologies intended for oral, transdermal, subcutaneous, vaginal, or rectal administration. Authored by eminent scientists in academia and nonprofit organizations involved in the development of antiretroviral drug products, this collection provides useful information for all those involved in HIV/AIDS treatment and prevention.

Consolidated Guidelines on the Use of Antiretroviral Drugs for Treating and Preventing HIV Infection

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Author :
Publisher :
ISBN 13 : 9789241549684
Total Pages : 429 pages
Book Rating : 4.5/5 (496 download)

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Book Synopsis Consolidated Guidelines on the Use of Antiretroviral Drugs for Treating and Preventing HIV Infection by : World Health Organization

Download or read book Consolidated Guidelines on the Use of Antiretroviral Drugs for Treating and Preventing HIV Infection written by World Health Organization and published by . This book was released on 2016 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: These guidelines provide guidance on the diagnosis of human immunodeficiency virus (HIV) infection, the use of antiretroviral (ARV) drugs for treating and preventing HIV infection and the care of people living with HIV. They are structured along the continuum of HIV testing, prevention, treatment and care. This edition updates the 2013 consolidated guidelines on the use of antiretroviral drugs following an extensive review of evidence and consultations in mid-2015, shared at the end of 2015, and now published in full in 2016. It is being published in a changing global context for HIV and for health more broadly.

Drug Delivery and Development of Anti-HIV Microbicides

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Author :
Publisher : CRC Press
ISBN 13 : 9814463566
Total Pages : 709 pages
Book Rating : 4.8/5 (144 download)

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Book Synopsis Drug Delivery and Development of Anti-HIV Microbicides by : José das Neves

Download or read book Drug Delivery and Development of Anti-HIV Microbicides written by José das Neves and published by CRC Press. This book was released on 2014-10-16 with total page 709 pages. Available in PDF, EPUB and Kindle. Book excerpt: The worldwide impact of HIV/AIDS is well recognized. This book provides for the first time a thorough and critical overview of current aspects, recent developments, and trends in the formulation and drug delivery concerning anti-HIV microbicides by leading scientists in the field. Additionally, pertinent regulatory aspects and socioeconomical issues related to the subject are discussed. In the absence of a cure, prophylaxis represents a cornerstone in the battle against infection. One promising strategy comprises the use around the time of sexual intercourse of vaginal/rectal products containing antiviral compounds, termed microbicides. It is now recognized that specific development of drug dosage forms and/or drug delivery systems is an indispensable aspect for the success of microbicides. Different groups strived over the last decade to optimize the biophysical and technological performance of traditional dosage forms (gels, tablets, and suppositories) to fulfill the specificities of microbicides use, without neglecting users’ preferences and affordability issues. Moreover, new formulation approaches, such as vaginal rings and films, nanotechnology-based systems, stimuli-sensitive formulations, targeted drug delivery systems, among others have been proposed and are currently undergoing pre-clinical or even clinical testing.

Novel Approaches Towards the Treatment of HIV Infection

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Author :
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (142 download)

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Book Synopsis Novel Approaches Towards the Treatment of HIV Infection by : Travis Lane Spurling

Download or read book Novel Approaches Towards the Treatment of HIV Infection written by Travis Lane Spurling and published by . This book was released on 1997 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Disease Control Priorities, Third Edition (Volume 6)

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Author :
Publisher : World Bank Publications
ISBN 13 : 1464805253
Total Pages : 1027 pages
Book Rating : 4.4/5 (648 download)

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Book Synopsis Disease Control Priorities, Third Edition (Volume 6) by : King K. Holmes

Download or read book Disease Control Priorities, Third Edition (Volume 6) written by King K. Holmes and published by World Bank Publications. This book was released on 2017-11-06 with total page 1027 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.

Neuro-AIDS

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Publisher : Nova Publishers
ISBN 13 : 9781594546105
Total Pages : 280 pages
Book Rating : 4.5/5 (461 download)

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Book Synopsis Neuro-AIDS by : Alireza Minagar

Download or read book Neuro-AIDS written by Alireza Minagar and published by Nova Publishers. This book was released on 2006 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the past two decades, the world scientific community has witnessed major achievements in our understanding of the pathogenesis of HIV infection of the nervous system and HIV-Associated Dementia (HAD). Despite these giant gains, nervous system involvement during AIDS remains a relentlessly progressive disease with a deadly fate in many cases. This book on NeuroAIDS provides a unique resource for both general neurologists as well as basic neuroscientists with profound interests for research on NeuroAIDS. This book has special emphasis on the mechanisms of disease development and progression of HIV-infected patients with NeuroAIDS. The contributors have provided the readers with comprehensive reviews on clinical manifestations of HAD, mechanisms of HIV entry into the central nervous system, the role of cytokines and chemokines in pathogenesis of NeuroAIDS, drug abuse and NeuroAIDS, virus load in HAD, allostasis in HIV and AIDS, stroke in AIDS patients, and neuroimaging of HIV infection of the central nervous system. In addition, there are chapters on Varicella Zoster virus infection of HIV-seropositive and AIDS patients, as well as the molecular basis for opioids and AIDS virus interactions.

Guidelines for the Psychosocially Assisted Pharmacological Treatment of Opioid Dependence

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Author :
Publisher : World Health Organization
ISBN 13 : 9241547545
Total Pages : 133 pages
Book Rating : 4.2/5 (415 download)

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Book Synopsis Guidelines for the Psychosocially Assisted Pharmacological Treatment of Opioid Dependence by : World Health Organization. Department of Mental Health and Substance Abuse

Download or read book Guidelines for the Psychosocially Assisted Pharmacological Treatment of Opioid Dependence written by World Health Organization. Department of Mental Health and Substance Abuse and published by World Health Organization. This book was released on 2009 with total page 133 pages. Available in PDF, EPUB and Kindle. Book excerpt: "These guidelines were produced by the World Health Organization (WHO), Department of Mental Health and Substance Abuse, in collaboration with the United Nations Office on Drugs and Crime (UNODC) a Guidelines Development Group of technical experts, and in consultation with the International Narcotics Control Board (INCB) secretariat and other WHO departments. WHO also wishes to acknowledge the financial contribution of UNODC and the Joint United Nations Programme on HIV/AIDS (UNAIDS) to this project. " - p. iv

HIV-1 Latency

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Author :
Publisher : Springer
ISBN 13 : 303002816X
Total Pages : 248 pages
Book Rating : 4.0/5 (3 download)

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Book Synopsis HIV-1 Latency by : Guido Silvestri

Download or read book HIV-1 Latency written by Guido Silvestri and published by Springer. This book was released on 2018-10-11 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume summarizes recent advances in understanding the mechanisms of HIV-1 latency, in characterizing residual viral reservoirs, and in developing targeted interventions to reduce HIV-1 persistence during antiretroviral therapy. Specific chapters address the molecular mechanisms that govern and regulate HIV-1 transcription and latency; assays and technical approaches to quantify viral reservoirs in humans and animal models; the complex interchange between viral reservoirs and the host immune system; computational strategies to model viral reservoir dynamics; and the development of therapeutic approaches that target viral reservoir cells. With contributions from an interdisciplinary group of investigators that cover a broad spectrum of subjects, from molecular virology to proof-of-principle clinical trials, this book is a valuable resource for basic scientists, translational investigators, infectious-disease physicians, individuals living with HIV/AIDS and the general public.

The Social Impact of AIDS in the United States

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Publisher : National Academies Press
ISBN 13 : 0309046289
Total Pages : 337 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis The Social Impact of AIDS in the United States by : National Research Council

Download or read book The Social Impact of AIDS in the United States written by National Research Council and published by National Academies Press. This book was released on 1993-02-01 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: Europe's "Black Death" contributed to the rise of nation states, mercantile economies, and even the Reformation. Will the AIDS epidemic have similar dramatic effects on the social and political landscape of the twenty-first century? This readable volume looks at the impact of AIDS since its emergence and suggests its effects in the next decade, when a million or more Americans will likely die of the disease. The Social Impact of AIDS in the United States addresses some of the most sensitive and controversial issues in the public debate over AIDS. This landmark book explores how AIDS has affected fundamental policies and practices in our major institutions, examining: How America's major religious organizations have dealt with sometimes conflicting values: the imperative of care for the sick versus traditional views of homosexuality and drug use. Hotly debated public health measures, such as HIV antibody testing and screening, tracing of sexual contacts, and quarantine. The potential risk of HIV infection to and from health care workers. How AIDS activists have brought about major change in the way new drugs are brought to the marketplace. The impact of AIDS on community-based organizations, from volunteers caring for individuals to the highly political ACT-UP organization. Coping with HIV infection in prisons. Two case studies shed light on HIV and the family relationship. One reports on some efforts to gain legal recognition for nonmarital relationships, and the other examines foster care programs for newborns with the HIV virus. A case study of New York City details how selected institutions interact to give what may be a picture of AIDS in the future. This clear and comprehensive presentation will be of interest to anyone concerned about AIDS and its impact on the country: health professionals, sociologists, psychologists, advocates for at-risk populations, and interested individuals.

Antiviral Drugs

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 0470455632
Total Pages : 468 pages
Book Rating : 4.4/5 (74 download)

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Book Synopsis Antiviral Drugs by : Wieslaw M. Kazmierski

Download or read book Antiviral Drugs written by Wieslaw M. Kazmierski and published by John Wiley & Sons. This book was released on 2011-08-23 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on new small molecule approaches to combat viral infections. The chapters describe the discovery and development from bench through the clinic of relatively recently-approved antiviral drugs and compounds in advanced clinical development. Organized by a virus (such as HIV, HCV, RSV, influenza, HBV and CMV) and written by top academic and industrial authorities in the field, the book provides a unique opportunity to study, understand and apply discovery and development principles and learning without the need for an individual to research, analyze and synthesize all immense sourcing references. Topics showcase challenges and solutions of issues encountered, offering tremendous experience accumulated over many years of research that will be particularly useful to basic and bench scientists as well as clinicians as they continue discovering and developing new drugs and therapies.

Drug Delivery Across Physiological Barriers

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Author :
Publisher : CRC Press
ISBN 13 : 9814669415
Total Pages : 410 pages
Book Rating : 4.8/5 (146 download)

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Book Synopsis Drug Delivery Across Physiological Barriers by : Silvia Muro

Download or read book Drug Delivery Across Physiological Barriers written by Silvia Muro and published by CRC Press. This book was released on 2016-04-27 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: Transport of pharmaceutical agents in the body is paramount to therapeutic efficacy. Advances in the past decades have rendered a remarkable improvement of drug delivery strategies, which has helped to increase the bioavailability of therapeutic agents by protecting them from degradation, targeting them to diseased sites, and controlling their circ

My Own Country

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Author :
Publisher : BookRags
ISBN 13 :
Total Pages : 42 pages
Book Rating : 4./5 ( download)

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Book Synopsis My Own Country by : Abraham Verghese

Download or read book My Own Country written by Abraham Verghese and published by BookRags. This book was released on 1998 with total page 42 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The AIDS Conspiracy

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Publisher : Columbia University Press
ISBN 13 : 0231149123
Total Pages : 240 pages
Book Rating : 4.2/5 (311 download)

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Book Synopsis The AIDS Conspiracy by : Nicoli Nattrass

Download or read book The AIDS Conspiracy written by Nicoli Nattrass and published by Columbia University Press. This book was released on 2012 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Examines conspiracy theories surrounding HIV and AIDS, focusing on two main widely believed falsehoods--that America manufactured AIDS to be a biological weapon and the belief that HIV is harmless and the true cause of AIDS are antiretroviral drugs.

Medical Apartheid

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Publisher : Vintage
ISBN 13 : 076791547X
Total Pages : 530 pages
Book Rating : 4.7/5 (679 download)

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Book Synopsis Medical Apartheid by : Harriet A. Washington

Download or read book Medical Apartheid written by Harriet A. Washington and published by Vintage. This book was released on 2008-01-08 with total page 530 pages. Available in PDF, EPUB and Kindle. Book excerpt: NATIONAL BOOK CRITICS CIRCLE AWARD WINNER • The first full history of Black America’s shocking mistreatment as unwilling and unwitting experimental subjects at the hands of the medical establishment. No one concerned with issues of public health and racial justice can afford not to read this masterful book. "[Washington] has unearthed a shocking amount of information and shaped it into a riveting, carefully documented book." —New York Times From the era of slavery to the present day, starting with the earliest encounters between Black Americans and Western medical researchers and the racist pseudoscience that resulted, Medical Apartheid details the ways both slaves and freedmen were used in hospitals for experiments conducted without their knowledge—a tradition that continues today within some black populations. It reveals how Blacks have historically been prey to grave-robbing as well as unauthorized autopsies and dissections. Moving into the twentieth century, it shows how the pseudoscience of eugenics and social Darwinism was used to justify experimental exploitation and shoddy medical treatment of Blacks. Shocking new details about the government’s notorious Tuskegee experiment are revealed, as are similar, less-well-known medical atrocities conducted by the government, the armed forces, prisons, and private institutions. The product of years of prodigious research into medical journals and experimental reports long undisturbed, Medical Apartheid reveals the hidden underbelly of scientific research and makes possible, for the first time, an understanding of the roots of the African American health deficit. At last, it provides the fullest possible context for comprehending the behavioral fallout that has caused Black Americans to view researchers—and indeed the whole medical establishment—with such deep distrust.

HIV/AIDS Treatment Drugs

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Author :
Publisher : Infobase Publishing
ISBN 13 : 1438102070
Total Pages : 121 pages
Book Rating : 4.4/5 (381 download)

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Book Synopsis HIV/AIDS Treatment Drugs by : Brigid M. Kane

Download or read book HIV/AIDS Treatment Drugs written by Brigid M. Kane and published by Infobase Publishing. This book was released on 2008 with total page 121 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drugs are everywhere--on our streets, in our homes, and in our schools--but the straight facts about drugs are not.

Frontiers in Clinical Drug Research: HIV

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Author :
Publisher : Bentham Science Publishers
ISBN 13 : 1681082012
Total Pages : 348 pages
Book Rating : 4.6/5 (81 download)

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Book Synopsis Frontiers in Clinical Drug Research: HIV by : Atta-ur-Rahman

Download or read book Frontiers in Clinical Drug Research: HIV written by Atta-ur-Rahman and published by Bentham Science Publishers. This book was released on 2015-11-27 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Frontiers in Clinical Drug Research – HIV is an eBook series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of acquired immune deficiency syndrome (AIDS) and other disorders associated with human immunodeficiency virus (HIV) infection. The scope of the eBook series covers a range of topics including the medicinal chemistry and pharmacology of natural and synthetic drugs employed in the treatment of AIDS (including HAART) and resulting complications, and the virology and immunological study of HIV and related viruses. Frontiers in Clinical Drug Research – HIV is a valuable resource for pharmaceutical scientists, clinicians and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in HIV/AIDS research. The second volume of this series features 5 chapters that cover a variety of topics including: - HIV-1 Integrase Inhibitors - HIV in vaginal mucosa - Long-Acting Antiretroviral Formulations -The world of people living with HIV/AIDS.